Pgm3 (phosphoglucomutase 3) - Rat Genome Database

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Gene: Pgm3 (phosphoglucomutase 3) Rattus norvegicus
Analyze
Symbol: Pgm3
Name: phosphoglucomutase 3
RGD ID: 1305221
Description: Predicted to enable phosphoacetylglucosamine mutase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process; hemopoiesis; and protein glycosylation. Predicted to act upstream of or within spermatogenesis. Human ortholog(s) of this gene implicated in immunodeficiency 23 and teratoma. Orthologous to human PGM3 (phosphoglucomutase 3); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; glycogen biosynthetic pathway; INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363109; phosphoacetylglucosamine mutase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8896,398,331 - 96,416,045 (-)NCBIGRCr8
mRatBN7.2887,518,317 - 87,536,021 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,517,701 - 87,536,022 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx893,199,592 - 93,217,282 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0891,398,793 - 91,416,483 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0889,239,804 - 89,257,497 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0894,225,513 - 94,243,230 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,225,515 - 94,243,215 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0893,738,656 - 93,756,367 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4891,810,223 - 91,827,293 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1891,828,427 - 91,845,308 (-)NCBI
Celera887,122,461 - 87,139,531 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fenpyroximate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The cellular fate of glucose and its relevance in type 2 diabetes. Bouche C, etal., Endocr Rev. 2004 Oct;25(5):807-30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Gene loss in human teratomas. Linder D, Proc Natl Acad Sci U S A. 1969 Jul;63(3):699-704.
5. Isoenzymes of hexokinase, 6-phosphogluconate dehydrogenase, phosphoglucomutase and lactate dehydrogenase in uterine cancer. Marshall MJ, etal., Br J Cancer. 1979 Sep;40(3):380-90.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. A phylogenetic approach to the identification of phosphoglucomutase genes. Whitehouse DB, etal., Mol Biol Evol. 1998 Apr;15(4):456-62.
Additional References at PubMed
PMID:6241468   PMID:6457599   PMID:7323947   PMID:11004509   PMID:12477932   PMID:17548465   PMID:24589341  


Genomics

Comparative Map Data
Pgm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8896,398,331 - 96,416,045 (-)NCBIGRCr8
mRatBN7.2887,518,317 - 87,536,021 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,517,701 - 87,536,022 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx893,199,592 - 93,217,282 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0891,398,793 - 91,416,483 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0889,239,804 - 89,257,497 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0894,225,513 - 94,243,230 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,225,515 - 94,243,215 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0893,738,656 - 93,756,367 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4891,810,223 - 91,827,293 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1891,828,427 - 91,845,308 (-)NCBI
Celera887,122,461 - 87,139,531 (-)NCBICelera
Cytogenetic Map8q31NCBI
PGM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38683,148,705 - 83,193,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl683,147,324 - 83,193,936 (-)EnsemblGRCh38hg38GRCh38
GRCh37683,860,447 - 83,903,619 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36683,935,347 - 83,959,654 (-)NCBINCBI36Build 36hg18NCBI36
Celera684,311,934 - 84,336,241 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef681,102,841 - 81,131,905 (-)NCBIHuRef
CHM1_1683,972,285 - 84,001,348 (-)NCBICHM1_1
T2T-CHM13v2.0684,373,968 - 84,417,223 (-)NCBIT2T-CHM13v2.0
Pgm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39986,423,997 - 86,453,927 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl986,436,430 - 86,453,895 (-)EnsemblGRCm39 Ensembl
GRCm38986,552,476 - 86,571,878 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl986,554,377 - 86,571,842 (-)EnsemblGRCm38mm10GRCm38
MGSCv37986,446,083 - 86,465,449 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36986,349,194 - 86,368,545 (-)NCBIMGSCv36mm8
Celera983,629,204 - 83,648,570 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map946.58NCBI
Pgm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541110,904,022 - 10,924,216 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541110,904,022 - 10,925,613 (-)NCBIChiLan1.0ChiLan1.0
PGM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25103,267,675 - 103,294,756 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16101,161,135 - 101,189,788 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0681,062,356 - 81,090,215 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1684,336,092 - 84,364,515 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl684,336,092 - 84,364,515 (-)Ensemblpanpan1.1panPan2
PGM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11243,582,472 - 43,611,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1243,584,940 - 43,611,777 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1243,398,757 - 43,424,981 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01244,352,674 - 44,378,899 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1244,352,396 - 44,378,862 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11243,692,121 - 43,718,325 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01243,640,874 - 43,667,265 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01243,801,971 - 43,828,223 (-)NCBIUU_Cfam_GSD_1.0
Pgm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494678,848,275 - 78,884,092 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365107,586,837 - 7,609,267 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365107,586,817 - 7,622,586 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl183,003,604 - 83,029,897 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1183,003,622 - 83,029,392 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2193,255,151 - 93,280,921 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PGM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1137,841,724 - 7,871,013 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl137,844,765 - 7,871,002 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040184,051,414 - 184,080,284 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479911,395,615 - 11,423,876 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479911,395,465 - 11,423,878 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pgm3
51 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:35
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000067699
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
RH132930  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2887,518,418 - 87,518,638 (+)MAPPERmRatBN7.2
Rnor_6.0894,225,615 - 94,225,834NCBIRnor6.0
Rnor_5.0893,738,758 - 93,738,977UniSTSRnor5.0
RGSC_v3.4891,809,693 - 91,809,912UniSTSRGSC3.4
Celera887,121,931 - 87,122,150UniSTS
RH 3.4 Map81001.1UniSTS
Cytogenetic Map8q31UniSTS
RH135322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2887,517,873 - 87,518,067 (+)MAPPERmRatBN7.2
Rnor_6.0894,225,070 - 94,225,263NCBIRnor6.0
Rnor_5.0893,738,213 - 93,738,406UniSTSRnor5.0
RGSC_v3.4891,809,148 - 91,809,341UniSTSRGSC3.4
Celera887,121,386 - 87,121,579UniSTS
RH 3.4 Map8999.7UniSTS
Cytogenetic Map8q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 18 23 21 4 21 1 1 74 35 33 10 1
Low 25 34 20 15 20 7 10 8 1 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000067699   ⟹   ENSRNOP00000062246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,517,701 - 87,535,984 (-)Ensembl
Rnor_6.0 Ensembl894,226,145 - 94,243,215 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084694   ⟹   ENSRNOP00000070465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,518,320 - 87,536,022 (-)Ensembl
Rnor_6.0 Ensembl894,225,515 - 94,243,137 (-)Ensembl
RefSeq Acc Id: NM_001401193   ⟹   NP_001388122
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,398,331 - 96,416,021 (-)NCBI
mRatBN7.2887,518,317 - 87,536,007 (-)NCBI
RefSeq Acc Id: XM_008766451   ⟹   XP_008764673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,398,331 - 96,416,029 (-)NCBI
mRatBN7.2887,518,740 - 87,536,021 (-)NCBI
Rnor_6.0894,225,911 - 94,243,230 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063265788   ⟹   XP_063121858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,398,331 - 96,416,045 (-)NCBI
RefSeq Acc Id: XM_063265789   ⟹   XP_063121859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8896,398,331 - 96,416,029 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008764673   ⟸   XM_008766451
- Peptide Label: isoform X1
- UniProtKB: A6I1U8 (UniProtKB/TrEMBL),   A6I1U9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000062246   ⟸   ENSRNOT00000067699
RefSeq Acc Id: ENSRNOP00000070465   ⟸   ENSRNOT00000084694
RefSeq Acc Id: NP_001388122   ⟸   NM_001401193
- UniProtKB: D3ZFX4 (UniProtKB/TrEMBL),   B2RYN0 (UniProtKB/TrEMBL),   A0A9K3Y705 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121858   ⟸   XM_063265788
- Peptide Label: isoform X1
- UniProtKB: A6I1U8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121859   ⟸   XM_063265789
- Peptide Label: isoform X2
- UniProtKB: A0A9K3Y705 (UniProtKB/TrEMBL),   B2RYN0 (UniProtKB/TrEMBL),   D3ZFX4 (UniProtKB/TrEMBL)
Protein Domains
Alpha-D-phosphohexomutase alpha/beta/alpha   Alpha-D-phosphohexomutase C-terminal   Phosphoacetylglucosamine mutase AMG1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFX4-F1-model_v2 AlphaFold D3ZFX4 1-552 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696169
Promoter ID:EPDNEW_R6684
Type:initiation region
Name:Pgm3_1
Description:phosphoglucomutase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0894,243,173 - 94,243,233EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305221 AgrOrtholog
BioCyc Gene G2FUF-29641 BioCyc
BioCyc Pathway UDPNACETYLGALSYN-PWY [UDP-N-acetyl-D-glucosamine biosynthesis II] BioCyc
BioCyc Pathway Image UDPNACETYLGALSYN-PWY BioCyc
Ensembl Genes ENSRNOG00000009515 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067699 ENTREZGENE
  ENSRNOT00000067699.2 UniProtKB/TrEMBL
  ENSRNOT00000084694.2 UniProtKB/TrEMBL
Gene3D-CATH Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 UniProtKB/TrEMBL
  Alpha-D-phosphohexomutase, C-terminal domain UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9027278 IMAGE-MGC_LOAD
InterPro A-D-PHexomutase_a/b/a-I UniProtKB/TrEMBL
  A-D-PHexomutase_a/b/a-I/II/III UniProtKB/TrEMBL
  A-D-PHexomutase_C UniProtKB/TrEMBL
  A-D-PHexomutase_C_sf UniProtKB/TrEMBL
  A-D-PHexomutase_CS UniProtKB/TrEMBL
  AMG1_II UniProtKB/TrEMBL
  AMG1_III UniProtKB/TrEMBL
  PAGM UniProtKB/TrEMBL
KEGG Report rno:363109 UniProtKB/TrEMBL
MGC_CLONE MGC:188729 IMAGE-MGC_LOAD
NCBI Gene 363109 ENTREZGENE
PANTHER PHOSPHOACETYLGLUCOSAMINE MUTASE UniProtKB/TrEMBL
  PHOSPHOACETYLGLUCOSAMINE MUTASE UniProtKB/TrEMBL
Pfam AMG1_II UniProtKB/TrEMBL
  AMG1_III UniProtKB/TrEMBL
  PGM_PMM_I UniProtKB/TrEMBL
  PGM_PMM_IV UniProtKB/TrEMBL
PhenoGen Pgm3 PhenoGen
PIRSF PAGM UniProtKB/TrEMBL
PROSITE PGM_PMM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009515 RatGTEx
Superfamily-SCOP A-D-PHexomutase_a/b/a-I/II/III UniProtKB/TrEMBL
  SSF55957 UniProtKB/TrEMBL
UniProt A0A0G2JY00_RAT UniProtKB/TrEMBL
  A0A9K3Y705 ENTREZGENE, UniProtKB/TrEMBL
  A6I1U6_RAT UniProtKB/TrEMBL
  A6I1U8 ENTREZGENE, UniProtKB/TrEMBL
  A6I1U9 ENTREZGENE, UniProtKB/TrEMBL
  B2RYN0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZFX4 ENTREZGENE
UniProt Secondary D3ZFX4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Pgm3  phosphoglucomutase 3   Pgm3_predicted  phosphoglucomutase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pgm3_predicted  phosphoglucomutase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED