Parp9 (poly(ADP-ribose) polymerase family member 9) - Rat Genome Database

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Gene: Parp9 (poly(ADP-ribose) polymerase family member 9) Chinchilla lanigera
Analyze
Symbol: Parp9
Name: poly(ADP-ribose) polymerase family member 9
RGD ID: 9060054
Description: ENCODES a protein that exhibits ADP-D-ribose binding (ortholog); enzyme binding (ortholog); enzyme inhibitor activity (ortholog); INVOLVED IN DNA damage checkpoint signaling (ortholog); double-strand break repair (ortholog); negative regulation of catalytic activity (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH alkaptonuria (ortholog); familial hypocalciuric hypercalcemia (ortholog); Primary Lymphedema with Myelodysplasia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly (ADP-ribose) polymerase family, member 9; poly [ADP-ribose] polymerase 9
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,770,577 - 21,804,717 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,770,158 - 21,806,091 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Parp9Chinchillaalkaptonuria  ISOPARP9 (Homo sapiens)8554872ClinVar Annotator: match by term: AlkaptonuriaClinVarPMID:12501223 more ...
Parp9Chinchillafamilial hypocalciuric hypercalcemia  ISOPARP9 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial hypocalciuric hypercalcemiaClinVarPMID:28492532
Parp9ChinchillaPrimary Lymphedema with Myelodysplasia  ISOPARP9 (Homo sapiens)8554872ClinVar Annotator: match by term: Lymphedema more ...ClinVarPMID:19449416 more ...


Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Parp9ChinchillaDNA damage checkpoint signaling involved_inISOPARP9 (Homo sapiens)9068941 PMID:28525742UniProtPMID:28525742
Parp9Chinchilladouble-strand break repair involved_inISOPARP9 (Homo sapiens)9068941 PMID:23230272UniProtPMID:23230272
Parp9Chinchillanegative regulation of catalytic activity involved_inISOPARP9 (Homo sapiens)9068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillanegative regulation of gene expression involved_inISOPARP9 (Homo sapiens)9068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillanegative regulation of transcription by RNA polymerase II involved_inISOPARP9 (Homo sapiens)9068941 PMID:16061477UniProtPMID:16061477
Parp9Chinchillapositive regulation of defense response to virus by host involved_inISOUniProtKB:P42224 and UniProtKB:Q8TDB69068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillapositive regulation of DNA-templated transcription involved_inISOUniProtKB:P42224 and UniProtKB:Q8TDB69068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillapositive regulation of protein localization to nucleus involved_inISOUniProtKB:Q8TDB69068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillapositive regulation of type II interferon-mediated signaling pathway involved_inISOPARP9 (Homo sapiens)9068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillapositive regulation of type II interferon-mediated signaling pathway involved_inISOParp9 (Mus musculus)9068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillapositive regulation of tyrosine phosphorylation of STAT protein involved_inISOPARP9 (Homo sapiens)9068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillapost-transcriptional regulation of gene expression involved_inISOPARP9 (Homo sapiens)9068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillaprotein poly-ADP-ribosylation NOT|involved_inISOPARP9 (Homo sapiens)9068941 PMID:16061477UniProtPMID:16061477
Parp9Chinchillaregulation of response to type II interferon involved_inISOPARP9 (Homo sapiens)9068941 PMID:16809771UniProtPMID:16809771
1 to 14 of 14 rows

Cellular Component

  

Molecular Function
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Parp9ChinchillaADP-D-ribose binding enablesISOPARP9 (Homo sapiens)9068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillaenzyme binding enablesISOUniProtKB:Q460N59068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillaenzyme inhibitor activity enablesISOPARP9 (Homo sapiens)9068941 PMID:27796300UniProtPMID:27796300
Parp9Chinchillahistone binding enablesISOUniProtKB:Q930799068941 PMID:26479788UniProtPMID:26479788
Parp9ChinchillaNAD+ binding NOT|enablesISOPARP9 (Homo sapiens)9068941 PMID:16061477UniProtPMID:16061477
Parp9ChinchillaNAD+ poly-ADP-ribosyltransferase activity NOT|enablesISOPARP9 (Homo sapiens)9068941 PMID:16061477UniProtPMID:16061477
Parp9ChinchillaNAD+ poly-ADP-ribosyltransferase activity enablesISOPARP9 (Homo sapiens)9068941 PMID:23230272UniProtPMID:23230272
Parp9ChinchillaNAD+-protein-C-terminal glycine ADP-ribosyltransferase activity enablesISOPARP9 (Homo sapiens)9068941 PMID:28525742UniProtPMID:28525742
Parp9Chinchillaprotein binding enablesISOUniProtKB:P42224 more ...9068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillaprotein binding enablesISOUniProtKB:P09874 and UniProtKB:Q8TDB69068941 PMID:23230272UniProtPMID:23230272
Parp9Chinchillaprotein binding enablesISOUniProtKB:Q8TDB69068941 PMID:16809771UniProtPMID:16809771
Parp9ChinchillaSTAT family protein binding enablesISOUniProtKB:P422249068941 PMID:26479788UniProtPMID:26479788
Parp9Chinchillatranscription corepressor activity enablesISOPARP9 (Homo sapiens)9068941 PMID:16061477UniProtPMID:16061477
Parp9Chinchillaubiquitin-like protein ligase binding enablesISOUniProtKB:Q8TDB69068941 PMID:28525742UniProtPMID:28525742
1 to 14 of 14 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Parp9ChinchillaADP-ribosylation pathway, mono and poly-ribosylation  ISOPARP9 (Homo sapiens)9068941 RGDPMID:26091342 and REF_RGD_ID:11100038

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Parp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,770,577 - 21,804,717 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,770,158 - 21,806,091 (-)NCBIChiLan1.0ChiLan1.0
PARP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383122,527,924 - 122,564,784 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3122,527,924 - 122,564,577 (-)EnsemblGRCh38hg38GRCh38
GRCh373122,246,771 - 122,283,631 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,729,461 - 123,766,114 (-)NCBINCBI36Build 36hg18NCBI36
Build 343123,729,462 - 123,766,114NCBI
Celera3120,656,569 - 120,693,333 (-)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3119,620,038 - 119,656,801 (-)NCBIHuRef
CHM1_13122,210,449 - 122,247,205 (-)NCBICHM1_1
T2T-CHM13v2.03125,247,222 - 125,284,030 (-)NCBIT2T-CHM13v2.0
Parp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,759,360 - 35,792,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,758,840 - 35,792,975 (+)EnsemblGRCm39 Ensembl
GRCm381635,938,470 - 35,972,621 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,938,470 - 35,972,605 (+)EnsemblGRCm38mm10GRCm38
MGSCv371635,938,556 - 35,972,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,858,217 - 35,892,352 (+)NCBIMGSCv36mm8
Celera1636,418,713 - 36,452,749 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.43NCBI
Parp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,286,282 - 78,320,409 (-)NCBIGRCr8
mRatBN7.21164,780,977 - 64,814,995 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,780,981 - 64,815,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1173,606,279 - 73,638,748 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,268,543 - 66,301,015 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,299,789 - 65,332,261 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01167,724,071 - 67,758,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,724,076 - 67,756,799 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,812,294 - 70,846,215 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,615,587 - 66,648,294 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,673,175 - 66,702,103 (-)NCBI
Celera1164,246,917 - 64,279,634 (-)NCBICelera
Cytogenetic Map11q22NCBI
PARP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,472,642 - 120,509,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,477,421 - 120,514,085 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,617,722 - 119,655,039 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,522,859 - 126,559,609 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,522,859 - 126,559,647 (-)Ensemblpanpan1.1panPan2
PARP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,643,439 - 25,676,979 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,643,883 - 25,677,462 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,667,797 - 25,701,331 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,878,555 - 25,912,166 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,878,555 - 25,912,539 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,675,496 - 25,709,331 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,718,998 - 25,752,634 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,276,577 - 26,310,190 (-)NCBIUU_Cfam_GSD_1.0
Parp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,677,266 - 128,715,188 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,806,818 - 8,840,746 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,806,824 - 8,845,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,966,562 - 138,000,846 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,960,987 - 138,000,862 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213147,581,288 - 147,621,200 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARP9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,297,526 - 58,336,243 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,298,046 - 58,337,124 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,011,893 - 108,049,617 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parp9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912827,547 - 859,199 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912827,112 - 968,501 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000014570   ⟹   ENSCLAP00000014412
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542721,770,577 - 21,804,717 (-)Ensembl
RefSeq Acc Id: XM_013515094   ⟹   XP_013370548
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542721,770,161 - 21,806,091 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515095   ⟹   XP_013370549
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542721,770,158 - 21,805,864 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515096   ⟹   XP_013370550
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542721,770,158 - 21,804,369 (-)NCBI
Sequence:
Protein RefSeqs XP_013370548 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370549 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370550 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000014412
  ENSCLAP00000014412.1
RefSeq Acc Id: XP_013370549   ⟸   XM_013515095
- UniProtKB: A0A8C2VEI9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370550   ⟸   XM_013515096
- UniProtKB: A0A8C2VEI9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370548   ⟸   XM_013515094
- UniProtKB: A0A8C2VEI9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000014412   ⟸   ENSCLAT00000014570
Macro   PARP catalytic



1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000009939 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014570 ENTREZGENE
  ENSCLAT00000014570.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.220.10 UniProtKB/TrEMBL
  3.90.228.10 UniProtKB/TrEMBL
InterPro Macro_dom UniProtKB/TrEMBL
  Macro_dom-like UniProtKB/TrEMBL
  Mono-ARTD/PARP UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
NCBI Gene Parp9 ENTREZGENE
PANTHER PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP9 UniProtKB/TrEMBL
Pfam Macro UniProtKB/TrEMBL
PROSITE MACRO UniProtKB/TrEMBL
  PARP_CATALYTIC UniProtKB/TrEMBL
SMART A1pp UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
  SSF52949 UniProtKB/TrEMBL
UniProt A0A8C2VEI9 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Parp9  poly(ADP-ribose) polymerase family member 9    poly (ADP-ribose) polymerase family, member 9  Symbol and/or name change 5135510 APPROVED