Cdk9 (cyclin dependent kinase 9) - Rat Genome Database

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Gene: Cdk9 (cyclin dependent kinase 9) Chinchilla lanigera
Analyze
Symbol: Cdk9
Name: cyclin dependent kinase 9
RGD ID: 9042778
Description: ENCODES a protein that exhibits 7SK snRNA binding (ortholog); chromatin binding (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to cytokine stimulus (ortholog); negative regulation of protein localization to chromatin (ortholog); nucleus localization (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; RNA polymerase II transcription pathway; ASSOCIATED WITH congenital disorder of glycosylation Iu (ortholog); congestive heart failure (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN cyclin/CDK positive transcription elongation factor complex (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-dependent kinase 9
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419873,289 - 883,160 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955419874,959 - 883,160 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cdk9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419873,289 - 883,160 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955419874,959 - 883,160 (-)NCBIChiLan1.0ChiLan1.0
CDK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,786,034 - 127,790,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,785,679 - 127,790,792 (+)EnsemblGRCh38hg38GRCh38
GRCh379130,548,313 - 130,553,071 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,588,152 - 129,592,184 (+)NCBINCBI36Build 36hg18NCBI36
Build 349127,627,890 - 127,631,917NCBI
Celera9101,199,168 - 101,203,915 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,164,574 - 100,169,598 (+)NCBIHuRef
CHM1_19130,699,854 - 130,704,602 (+)NCBICHM1_1
T2T-CHM13v2.09139,993,485 - 139,998,243 (+)NCBIT2T-CHM13v2.0
Cdk9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,595,794 - 32,608,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,595,796 - 32,603,088 (-)EnsemblGRCm39 Ensembl
GRCm38232,705,782 - 32,712,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,705,784 - 32,713,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,561,302 - 32,568,304 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,529,447 - 32,534,794 (-)NCBIMGSCv36mm8
Celera232,412,389 - 32,419,391 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Cdk9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,394,168 - 36,399,016 (-)NCBIGRCr8
mRatBN7.2315,996,467 - 16,001,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,996,468 - 16,002,410 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx319,065,041 - 19,069,877 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,650,044 - 27,654,880 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,901,304 - 25,906,154 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,742,269 - 11,747,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,742,266 - 11,747,113 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,081,164 - 17,086,012 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,672,861 - 11,677,709 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,569,232 - 11,574,081 (-)NCBI
Celera310,737,357 - 10,742,205 (-)NCBICelera
Cytogenetic Map3p11NCBI
CDK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,558,761 - 11,569,295 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,561,106 - 11,571,580 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,905,468 - 98,909,923 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,580,862 - 127,584,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,580,862 - 127,584,935 (+)Ensemblpanpan1.1panPan2
CDK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,615,271 - 55,619,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,615,827 - 55,620,236 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,808,829 - 54,812,940 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,536,951 - 56,541,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,536,954 - 56,541,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,296,987 - 55,301,098 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,611,719 - 55,615,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,703,144 - 55,707,256 (-)NCBIUU_Cfam_GSD_1.0
Cdk9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,678,357 - 195,682,223 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,446,858 - 15,452,796 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,446,864 - 15,450,750 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,276,841 - 268,281,052 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,277,083 - 268,280,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,142,973 - 302,146,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,342,240 - 10,346,792 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,342,801 - 10,346,502 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,874,123 - 5,879,334 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247607,760,474 - 7,765,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000012268   ⟹   ENSCLAP00000012127
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955419873,289 - 883,160 (-)Ensembl
RefSeq Acc Id: XM_005382409   ⟹   XP_005382466
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955419874,959 - 883,160 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005382466 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000012127
  ENSCLAP00000012127.1
RefSeq Acc Id: XP_005382466   ⟸   XM_005382409
- Sequence:
Ensembl Acc Id: ENSCLAP00000012127   ⟸   ENSCLAT00000012268
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008361 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012268 ENTREZGENE
  ENSCLAT00000012268.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CDK UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Cdk9 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 9 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VBE6_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cdk9  cyclin dependent kinase 9    cyclin-dependent kinase 9  Symbol and/or name change 5135510 APPROVED