Dyrk1a (dual specificity tyrosine phosphorylation regulated kinase 1A) - Rat Genome Database

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Gene: Dyrk1a (dual specificity tyrosine phosphorylation regulated kinase 1A) Chinchilla lanigera
Analyze
Symbol: Dyrk1a
Name: dual specificity tyrosine phosphorylation regulated kinase 1A
RGD ID: 8918371
Description: ENCODES a protein that exhibits actin binding (ortholog); cyclin binding (ortholog); cytoskeletal protein binding (ortholog); INVOLVED IN calcineurin-NFAT signaling cascade (ortholog); cardiac muscle hypertrophy (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 7 (ortholog); FOUND IN actin filament (ortholog); axon (ortholog); centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dual specificity tyrosine-phosphorylation-regulated kinase 1A; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540736,453,098 - 36,589,382 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540736,456,628 - 36,588,940 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
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Reference
Notes
Source
Original Reference(s)
Dyrk1aChinchillaCardiomegaly treatmentISODyrk1a (Rattus norvegicus)9068941 RGDPMID:24524606 more ...
Dyrk1aChinchillaCardiomegaly  ISODyrk1a (Rattus norvegicus)9068941protein:decreased expression:heart (rat)RGDPMID:19906449 and REF_RGD_ID:401959215
Dyrk1aChinchillacongestive heart failure treatmentISODyrk1a (Rattus norvegicus)9068941associated with myocardial infarctionRGDPMID:26067684 and REF_RGD_ID:11097969
Dyrk1aChinchilladilated cardiomyopathy severityISODyrk1a (Rattus norvegicus)9068941rat cDNA in mouse modelRGDPMID:27056896 and REF_RGD_ID:401959209
Dyrk1aChinchillaDown syndrome  ISODYRK1A (Homo sapiens)9068941protein:increased expression:brain (human)RGDPMID:18658135 and REF_RGD_ID:401940180
Dyrk1aChinchillaDown syndrome treatmentISODyrk1a (Mus musculus)9068941 RGDPMID:23220201 more ...
Dyrk1aChinchillaDown syndrome  ISODYRK1A (Homo sapiens)9068941protein:increased expression:brain:RGDPMID:18696092 and REF_RGD_ID:14974029
Dyrk1aChinchillaFebrile Seizures susceptibilityISODyrk1a (Mus musculus)9068941 RGDPMID:29223763 and REF_RGD_ID:27095962
Dyrk1aChinchillahyperhomocysteinemia  ISODyrk1a (Rattus norvegicus)9068941protein:decreased expression:heart (rat)RGDPMID:19906449 and REF_RGD_ID:401959215
Dyrk1aChinchillamyocardial infarction treatmentISODyrk1a (Rattus norvegicus)9068941associated with heart failure more ...RGDPMID:26067684 and REF_RGD_ID:11097969
Dyrk1aChinchillarenovascular hypertension treatmentISODyrk1a (Rattus norvegicus)9068941 RGDPMID:26619200 and REF_RGD_ID:401940196
1 to 11 of 11 rows
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Original Reference(s)
Dyrk1aChinchillaamyotrophic lateral sclerosis type 1  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Amyotrophic lateral sclerosis type 1ClinVarPMID:17237124 more ...
Dyrk1aChinchillaautism spectrum disorder  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:25741868 more ...
Dyrk1aChinchillaautosomal dominant intellectual developmental disorder 7  ISODYRK1A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
Dyrk1aChinchilladevelopmental and epileptic encephalopathy 11  ISODYRK1A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17576681 more ...
Dyrk1aChinchillaDevelopmental Disabilities  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25167861 more ...
Dyrk1aChinchillaenophthalmos  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: EnophthalmosClinVarPMID:25167861 more ...
Dyrk1aChinchillaepilepsy  ISODYRK1A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:18414213 more ...
Dyrk1aChinchillaepilepsy  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: SeizureClinVarPMID:18414213 more ...
Dyrk1aChinchillaFamilial Platelet Disorder with Associated Myeloid Malignancy  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1ClinVarPMID:17237124 more ...
Dyrk1aChinchillageneralized epilepsy  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Generalized-onset seizureClinVarPMID:25167861 more ...
Dyrk1aChinchillagenetic disease  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:18414213 more ...
Dyrk1aChinchillaimmunodeficiency 28  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 28ClinVarPMID:17237124 more ...
Dyrk1aChinchillaintellectual disability  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:23099646 more ...
Dyrk1aChinchillaintellectual disability  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:17576681 more ...
Dyrk1aChinchillaintellectual disability  ISODYRK1A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17576681 more ...
Dyrk1aChinchillamicrocephaly  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: MicrocephalyClinVarPMID:25167861 more ...
Dyrk1aChinchillamicrophthalmia  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: MicrophthalmiaClinVarPMID:25167861 more ...
Dyrk1aChinchillaNeurodevelopmental Disorders  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868 and PMID:28492532
Dyrk1aChinchillaspermatogenic failure 5  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: Male infertility with spermatogenesis disorderClinVarPMID:25741868
Dyrk1aChinchillasudden infant death syndrome  ISODYRK1A (Homo sapiens)8554872ClinVar Annotator: match by term: SUDDEN INFANT DEATH SYNDROMEClinVarPMID:25741868
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Original Reference(s)
Dyrk1aChinchillapancreatic cancer  ISODYRK1A (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:31838052
Object Symbol
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Original Reference(s)
Dyrk1aChinchillaDown syndrome  ISODyrk1a (Mus musculus)9068941OMIM:190685MouseDO 
Object Symbol
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Original Reference(s)
Dyrk1aChinchillaautosomal dominant intellectual developmental disorder 7  ISODYRK1A (Homo sapiens)7240710 OMIM 


Biological Process
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Original Reference(s)
Dyrk1aChinchillacalcineurin-NFAT signaling cascade  ISODyrk1a (Rattus norvegicus)9068941 RGDPMID:21273244 and REF_RGD_ID:401940178
Dyrk1aChinchillacardiac muscle hypertrophy  ISODyrk1a (Rattus norvegicus)9068941 RGDPMID:19906449 and REF_RGD_ID:401959215
Dyrk1aChinchillacircadian rhythm involved_inISODyrk1a (Mus musculus)9068941 PMID:20123978UniProtPMID:20123978
Dyrk1aChinchillanegative regulation of cell cycle  ISODyrk1a (Rattus norvegicus)9068941 RGDPMID:27056896 and REF_RGD_ID:401959209
Dyrk1aChinchillanegative regulation of DNA damage response, signal transduction by p53 class mediator involved_inISODyrk1a (Mus musculus)9068941 PMID:20736167BHF-UCLPMID:20736167
Dyrk1aChinchillanegative regulation of gene expression  ISOCcnd2 more ...9068941 RGDPMID:27056896 and REF_RGD_ID:401959209
Dyrk1aChinchillanegative regulation of heterochromatin formation involved_inISODYRK1A (Homo sapiens)9068941 PMID:24820035GO_CentralPMID:24820035
Dyrk1aChinchillanegative regulation of microtubule polymerization involved_inISODyrk1a (Mus musculus)9068941 PMID:17906291ARUK-UCLPMID:17906291
Dyrk1aChinchillanegative regulation of mRNA splicing, via spliceosome acts_upstream_of_or_withinISODyrk1a (Mus musculus)9068941 PMID:21470964MGIPMID:21470964
Dyrk1aChinchillanegative regulation of protein phosphorylation  ISORb19068941 RGDPMID:27056896 and REF_RGD_ID:401959209
Dyrk1aChinchillapeptidyl-serine phosphorylation involved_inISODyrk1a (Rattus norvegicus)9068941PMID:22767602UniProtPMID:22767602 and REF_RGD_ID:8554210
Dyrk1aChinchillapeptidyl-serine phosphorylation involved_inISODyrk1a (Mus musculus)9068941 PMID:20123978UniProtPMID:20123978
Dyrk1aChinchillapeptidyl-tyrosine autophosphorylation involved_inISODyrk1a (Mus musculus)9068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillapeptidyl-tyrosine phosphorylation involved_inISODyrk1a (Rattus norvegicus)9068941PMID:8631952UniProtPMID:8631952 and REF_RGD_ID:728738
Dyrk1aChinchillapeptidyl-tyrosine phosphorylation acts_upstream_of_or_withinISODyrk1a (Mus musculus)9068941 PMID:21470964MGIPMID:21470964
Dyrk1aChinchillapeptidyl-tyrosine phosphorylation acts_upstream_of_or_withinISODYRK1A (Homo sapiens)9068941 PMID:9748265MGIPMID:9748265
Dyrk1aChinchillapositive regulation of RNA splicing involved_inISODYRK1A (Homo sapiens)9068941 PMID:28377597ARUK-UCLPMID:28377597
Dyrk1aChinchillapositive regulation of RNA splicing involved_inISODyrk1a (Rattus norvegicus)9068941PMID:28377597ARUK-UCLPMID:28377597 and REF_RGD_ID:13464257
Dyrk1aChinchillaprotein autophosphorylation involved_inISODyrk1a (Rattus norvegicus)9068941PMID:8631952UniProtPMID:8631952 and REF_RGD_ID:728738
Dyrk1aChinchillaprotein import into nucleus  ISODyrk1a (Rattus norvegicus)9068941 RGDPMID:21273244 and REF_RGD_ID:401940178
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Cellular Component
1 to 20 of 21 rows

  
Object Symbol
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Original Reference(s)
Dyrk1aChinchillaactin filament located_inISOUniProtKB:P607099068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillaaxon located_inISODyrk1a (Mus musculus)9068941 PMID:21878370ARUK-UCLPMID:21878370
Dyrk1aChinchillacentrosome located_inISODYRK1A (Homo sapiens)9068941 HPAGO_REF:0000052
Dyrk1aChinchillacytoplasm located_inISODyrk1a (Mus musculus)9068941 PMID:21878370ARUK-UCLPMID:21878370
Dyrk1aChinchillacytoplasm located_inISODYRK1A (Homo sapiens)9068941 PMID:15694837UniProtPMID:15694837
Dyrk1aChinchillacytoskeleton located_inISODYRK1A (Homo sapiens)9068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillacytoskeleton located_inISODyrk1a (Mus musculus)9068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillacytosol located_inISODYRK1A (Homo sapiens)9068941 HPAGO_REF:0000052
Dyrk1aChinchilladendrite located_inISODyrk1a (Mus musculus)9068941 PMID:21878370ARUK-UCLPMID:21878370
Dyrk1aChinchillamicrotubule located_inISOUniProtKB:P683669068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillaneurofilament located_inISOUniProtKB:P120369068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillanuclear speck located_inISODyrk1a (Rattus norvegicus)9068941PMID:9748265UniProtPMID:9748265 and REF_RGD_ID:8554265
Dyrk1aChinchillanuclear speck located_inISODYRK1A (Homo sapiens)9068941 HPAGO_REF:0000052
Dyrk1aChinchillanuclear speck located_inISODyrk1a (Rattus norvegicus)9068941PMID:22767602UniProtPMID:22767602 and REF_RGD_ID:8554210
Dyrk1aChinchillanucleolus NOT|located_inISODyrk1a (Rattus norvegicus)9068941PMID:9748265UniProtPMID:9748265 and REF_RGD_ID:8554265
Dyrk1aChinchillanucleoplasm located_inISODYRK1A (Homo sapiens)9068941 HPAGO_REF:0000052
Dyrk1aChinchillanucleus located_inISODYRK1A (Homo sapiens)9068941 PMID:15694837 and PMID:23415227UniProtPMID:15694837 and PMID:23415227
Dyrk1aChinchillanucleus located_inISODyrk1a (Mus musculus)9068941 PMID:21878370 and PMID:9070862ARUK-UCLPMID:21878370 and PMID:9070862
Dyrk1aChinchillanucleus located_inISODyrk1a (Rattus norvegicus)9068941PMID:9748265UniProtPMID:9748265 and REF_RGD_ID:8554265
Dyrk1aChinchillanucleus is_active_inISODYRK1A (Homo sapiens)9068941 PMID:25620562UniProtPMID:25620562
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Molecular Function
1 to 20 of 43 rows

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Dyrk1aChinchillaactin binding enablesISOUniProtKB:P607099068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillacyclin binding  ISOCcnd1 more ...9068941rat constructs in human cellsRGDPMID:27056896 and REF_RGD_ID:401959209
Dyrk1aChinchillacytoskeletal protein binding enablesISOUniProtKB:P120369068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillahistone H3T45 kinase activity enablesISODYRK1A (Homo sapiens)9068941 PMID:24820035GO_CentralPMID:24820035
Dyrk1aChinchillaidentical protein binding enablesISOUniProtKB:Q13627-19068941 PMID:23665168IntActPMID:23665168
Dyrk1aChinchillaidentical protein binding enablesISOUniProtKB:Q612149068941 PMID:21965663 and PMID:9070862IntActPMID:21965663 and PMID:9070862
Dyrk1aChinchillanon-membrane spanning protein tyrosine kinase activity enablesISODYRK1A (Homo sapiens)9068941 PMID:9748265MGIPMID:9748265
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:Q5T7499068941 PMID:32296183IntActPMID:32296183
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:Q9ERC89068941 PMID:35914814IntActPMID:35914814
Dyrk1aChinchillaprotein binding enablesISOPR:Q620939068941 PMID:21470964MGIPMID:21470964
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:P53805-2 and UniProtKB:Q9JHG69068941 PMID:21965663IntActPMID:21965663
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:Q9R1949068941 PMID:20123978UniProtPMID:20123978
Dyrk1aChinchillaprotein binding enablesISOPR:Q99NG09068941 PMID:15199138MGIPMID:15199138
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:P06400 more ...9068941 PMID:32707033IntActPMID:32707033
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:P619629068941 PMID:14593110 more ...IntActPMID:14593110 more ...
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:Q7Z698 and UniProtKB:Q7Z6999068941 PMID:20736167BHF-UCLPMID:20736167
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:Q12815 and UniProtKB:Q9BRK49068941 PMID:26949739IntActPMID:26949739
Dyrk1aChinchillaprotein binding  ISORGDID:37179068941 RGDPMID:28755400 and REF_RGD_ID:401959218
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:P607099068941 PMID:24327345ARUK-UCLPMID:24327345
Dyrk1aChinchillaprotein binding enablesISOUniProtKB:Q925619068941 PMID:15694837UniProtPMID:15694837
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#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
PMID:22301074   PMID:30032202  



Dyrk1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540736,453,098 - 36,589,382 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540736,456,628 - 36,588,940 (+)NCBIChiLan1.0ChiLan1.0
DYRK1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382137,365,573 - 37,526,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2137,365,573 - 37,526,358 (+)EnsemblGRCh38hg38GRCh38
GRCh372138,737,875 - 38,898,660 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362137,661,729 - 37,809,549 (+)NCBINCBI36Build 36hg18NCBI36
Build 342137,714,470 - 37,809,347NCBI
Celera2123,938,247 - 24,086,068 (+)NCBICelera
Cytogenetic Map21q22.13NCBI
HuRef2124,215,875 - 24,363,782 (+)NCBIHuRef
CHM1_12138,301,002 - 38,448,854 (+)NCBICHM1_1
T2T-CHM13v2.02135,747,888 - 35,908,739 (+)NCBIT2T-CHM13v2.0
Dyrk1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391694,370,770 - 94,496,378 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1694,370,869 - 94,496,376 (+)EnsemblGRCm39 Ensembl
GRCm381694,569,947 - 94,695,519 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1694,570,010 - 94,695,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv371694,791,813 - 94,917,126 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361694,720,258 - 94,801,189 (+)NCBIMGSCv36mm8
Celera1695,699,096 - 95,783,175 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1655.3NCBI
Dyrk1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81147,360,824 - 47,479,033 (+)NCBIGRCr8
mRatBN7.21133,890,706 - 34,009,420 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,890,490 - 34,009,420 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1142,573,541 - 42,666,554 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,244,902 - 35,337,921 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01134,390,728 - 34,483,971 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,858,339 - 34,958,733 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,865,532 - 34,956,536 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01138,453,019 - 38,550,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,879,733 - 34,970,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11134,935,975 - 35,027,241 (+)NCBI
Celera1134,444,072 - 34,535,020 (-)NCBICelera
Cytogenetic Map11q11NCBI
DYRK1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22233,475,597 - 33,629,787 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12128,339,782 - 28,489,307 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02123,729,204 - 23,878,820 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12137,092,172 - 37,231,916 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2137,137,253 - 37,231,987 (+)Ensemblpanpan1.1panPan2
DYRK1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13132,564,970 - 32,655,232 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3132,511,502 - 32,652,572 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3131,572,154 - 31,719,378 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03131,812,898 - 31,959,979 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3131,811,351 - 31,960,042 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13131,682,502 - 31,829,001 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03131,695,751 - 31,842,602 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03132,186,102 - 32,332,696 (+)NCBIUU_Cfam_GSD_1.0
Dyrk1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497132,044,360 - 32,150,716 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365005,316,164 - 5,404,353 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365005,317,109 - 5,423,593 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYRK1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13201,009,480 - 201,159,948 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113201,008,506 - 201,159,946 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213211,096,538 - 211,247,962 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYRK1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1281,318,509 - 81,467,227 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl281,425,902 - 81,467,677 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660549,164,197 - 9,315,412 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dyrk1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474526,180,864 - 26,315,234 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474526,180,858 - 26,316,848 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000017409   ⟹   ENSCLAP00000017240
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540736,453,098 - 36,589,382 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000017410   ⟹   ENSCLAP00000017241
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540736,456,628 - 36,589,382 (+)Ensembl
RefSeq Acc Id: XM_005375747   ⟹   XP_005375804
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540736,480,234 - 36,588,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375749   ⟹   XP_005375806
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540736,456,628 - 36,588,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375750   ⟹   XP_005375807
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540736,456,628 - 36,588,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375751   ⟹   XP_005375808
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540736,498,333 - 36,588,940 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504724   ⟹   XP_013360178
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540736,482,237 - 36,588,940 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs XP_005375804 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375806 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375807 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375808 (Get FASTA)   NCBI Sequence Viewer  
  XP_013360178 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017240
  ENSCLAP00000017240.1
  ENSCLAP00000017241
  ENSCLAP00000017241.1
1 to 9 of 9 rows
RefSeq Acc Id: XP_005375806   ⟸   XM_005375749
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005375807   ⟸   XM_005375750
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005375804   ⟸   XM_005375747
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005375808   ⟸   XM_005375751
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013360178   ⟸   XM_013504724
- Peptide Label: isoform X2
- Sequence:
Protein kinase



1 to 24 of 24 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000011834 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017409 ENTREZGENE
  ENSCLAT00000017409.1 UniProtKB/TrEMBL
  ENSCLAT00000017410 ENTREZGENE
  ENSCLAT00000017410.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PKc_DYR1A/1B UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_dual-spec_kinase UniProtKB/TrEMBL
NCBI Gene Dyrk1a ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN KINASE UniProtKB/TrEMBL
  PTHR24058:SF121 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VN77_CHILA UniProtKB/TrEMBL
  A0A8C2VQ93_CHILA UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Dyrk1a  dual specificity tyrosine phosphorylation regulated kinase 1A    dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A  Symbol and/or name change 5135510 APPROVED