Myoc (myocilin) - Rat Genome Database

Name: Myoc
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Myoc (myocilin) Chinchilla lanigera

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Symbol:

Myoc

Name:

myocilin

RGD ID:

8776781

Description:

ENCODES a protein that exhibits fibronectin binding (ortholog); frizzled binding (ortholog); myosin light chain binding (ortholog); INVOLVED IN bone development (ortholog); cellular response to nerve growth factor stimulus (ortholog); clustering of voltage-gated sodium channels (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); autoimmune lymphoproliferative syndrome (ortholog); Brain Injuries (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); cytoplasmic vesicle (ortholog); endoplasmic reticulum (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

myocilin, trabecular meshwork inducible glucocorticoid response

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYOC (myocilin)	NCBI	Ortholog
Mus musculus (house mouse):	Myoc (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Myoc (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYOC (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MYOC (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Myoc (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYOC (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MYOC (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Myoc (myocilin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	12,182,046 - 12,199,669 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	12,182,115 - 12,194,683 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

1q24 Deletion Syndrome (ISO)

autoimmune lymphoproliferative syndrome (ISO)

Brain Injuries (ISO)

buphthalmos (ISO)

congestive heart failure (ISO)

Experimental Liver Cirrhosis (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

glaucoma (ISO)

Glaucoma 1, Open Angle, E (ISO)

juvenile glaucoma (ISO)

low tension glaucoma (ISO)

membranoproliferative glomerulonephritis (ISO)

ocular hypertension (ISO)

open-angle glaucoma (ISO)

parathyroid carcinoma (ISO)

primary open angle glaucoma (ISO)

severe combined immunodeficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone development (ISO)

cellular response to nerve growth factor stimulus (ISO)

clustering of voltage-gated sodium channels (ISO)

ERBB2-ERBB3 signaling pathway (ISO)

myelination in peripheral nervous system (ISO)

negative regulation of cell-matrix adhesion (ISO)

negative regulation of Rho protein signal transduction (ISO)

negative regulation of stress fiber assembly (ISO)

nerve development (ISO)

neuron projection development (ISO)

non-canonical Wnt signaling pathway (ISO)

osteoblast differentiation (ISO)

positive regulation of cell migration (ISO)

positive regulation of focal adhesion assembly (ISO)

positive regulation of JNK cascade (ISO)

positive regulation of mitochondrial depolarization (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of stress fiber assembly (ISO)

positive regulation of substrate adhesion-dependent cell spreading (ISO)

regulation of MAPK cascade (ISO)

skeletal muscle hypertrophy (ISO)

Cellular Component

collagen-containing extracellular matrix (ISO)

cytoplasmic vesicle (ISO)

endoplasmic reticulum (ISO)

extracellular space (ISO)

Golgi apparatus (ISO)

mesaxon (ISO)

mitochondrial inner membrane (ISO)

mitochondrial intermembrane space (ISO)

mitochondrial outer membrane (ISO)

myelin sheath abaxonal region (ISO)

node of Ranvier (ISO)

Schmidt-Lanterman incisure (ISO)

Molecular Function

fibronectin binding (ISO)

frizzled binding (ISO)

myosin light chain binding (ISO)

protein binding (ISO)

receptor tyrosine kinase binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Myoc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	12,182,046 - 12,199,669 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	12,182,115 - 12,194,683 (-)	NCBI	ChiLan1.0	ChiLan1.0

MYOC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	171,635,417 - 171,652,688 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	171,635,417 - 171,652,688 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	171,604,557 - 171,621,828 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	169,871,180 - 169,888,396 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	168,336,215 - 168,353,430	NCBI
Celera	1	144,713,951 - 144,731,166 (-)	NCBI		Celera
Cytogenetic Map	1	q24.3	NCBI
HuRef	1	142,827,834 - 142,845,046 (-)	NCBI		HuRef
CHM1_1	1	173,026,640 - 173,043,840 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	170,991,882 - 171,009,153 (-)	NCBI		T2T-CHM13v2.0

Myoc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	162,466,719 - 162,477,263 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	162,466,724 - 162,477,262 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	162,639,150 - 162,649,694 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	162,639,155 - 162,649,693 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	164,569,281 - 164,579,825 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	164,475,844 - 164,486,368 (+)	NCBI		MGSCv36	mm8
Celera	1	165,085,895 - 165,096,434 (+)	NCBI		Celera
Cytogenetic Map	1	H2.1	NCBI
cM Map	1	70.29	NCBI

Myoc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	77,509,963 - 77,520,361 (+)	NCBI		GRCr8
mRatBN7.2	13	74,976,730 - 74,987,128 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	74,976,730 - 74,987,127 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	77,554,373 - 77,564,765 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	78,858,850 - 78,869,297 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	76,118,721 - 76,129,168 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	80,517,531 - 80,527,928 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	80,517,536 - 80,527,928 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	85,409,611 - 85,420,008 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	78,303,830 - 78,314,228 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	78,318,017 - 78,328,415 (+)	NCBI
Celera	13	74,726,592 - 74,736,986 (+)	NCBI		Celera
Cytogenetic Map	13	q22	NCBI

MYOC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	78,104,233 - 78,121,545 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	77,778,772 - 77,797,111 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	147,128,541 - 147,146,227 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	150,841,630 - 150,858,628 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	150,841,630 - 150,858,628 (-)	Ensembl	panpan1.1		panPan2

MYOC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	27,335,314 - 27,346,821 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	27,335,314 - 27,346,820 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	26,857,046 - 26,868,545 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	27,136,587 - 27,148,065 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	27,136,391 - 27,148,079 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	26,988,106 - 26,999,596 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	27,022,462 - 27,033,986 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	27,264,790 - 27,276,291 (+)	NCBI		UU_Cfam_GSD_1.0

Myoc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	97,697,971 - 97,710,064 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	15,544,660 - 15,556,857 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	15,544,733 - 15,556,813 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYOC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	114,087,378 - 114,098,745 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	114,087,370 - 114,098,765 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	125,551,261 - 125,562,662 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYOC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	57,458,615 - 57,475,329 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	57,459,374 - 57,475,322 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	59,088,230 - 59,104,345 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Myoc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	10,065,788 - 10,080,680 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624771	10,066,170 - 10,080,257 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005374847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01005911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01005912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01011840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000017581 ⟹ ENSCLAP00000017411

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955406	12,182,046 - 12,199,669 (-)	Ensembl

RefSeq Acc Id:

XM_005374847 ⟹ XP_005374904

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955406	12,182,115 - 12,194,683 (-)	NCBI

Sequence:

show sequence

CCTCCCTCGGGCTCAGGCAAGAGCCAGGAGGCCCACCCGTCCAGACACCCGTGGGGCAGCAGAG
CTTTGCCGAGGAAGCCTCCCTCAGCCTCTGTACTGAGGCTCTTCCTTGTCCTTGCTCCAGCTGC
AGGCCCAAGATGCCAGCTGTCCAGCTGCTGCTGCTGGCCTGCCTGGTGTGGGGAGCAGGGGCCA
GGGCAGCCCAGCTCCGCAAGGCCAATGATCGGAGTGGCCGGTGCCAGTACACCTTCAGTGTGGC
CAGCCCCAATGAATCCAGCTGCCCCGAGCAGGGCCAGGCCATGGCGGCCATCCAAGACCTACAG
AGAGACAGCAGCACCCAGCATGCAGAGCTGGAGTCCACCAAAGCCCGGCTCAGCTCCCTGGAGA
GCCTCCTCCACCGGCTGAACTTGGACCAGGTTGCTGGGCCCCAGGAGACCCAGGAAGGGCCACA
GAGGCAGGTAGATGCCCTGAGGAGGGACCGGGACCGGCTGGAGACCCAAGCCAGGGAGCTGGAG
GTGGCCTATAGCAACCTCCTTCGGGACAAATCAGCACTGGAGGAAGAGAAGAGGCGACTGGGGC
AGGAGAACGAGGAGCTGGCCAGGAGGCTGGAAAGCAGCCTCCAGGAGGCGGCGAGGCTGAGACG
GGGCCAGTGCCTCCAGGCCCGGGTCCCCTCTCAGGACATTCTGCCAGGCGCCAGGGAAGTTTCT
CAGTGGAATCTGGACAGTTTGGCCTTCCAAGAATTGAAGTCAGAGTTGACTGAAGTTCCTGCTT
CCGGAATCTTGAAGGAGAGCCCGTCTGACCGTCCCAGGACTGAGGAGGGAAACAATGGATGTGG
ACAACTAGTTTGGGTGGGAGAGCCTGTCACTCTGAGGACTGCTGAGACGATCACTGGCAAGTAT
GGAGTGTGGATGAGGGACCCCAAACCCACGTACCCCTACACCCGGGAGACCACATGGAGAATTG
ACACGGTTGGCGTAGACATCCGCCAGGTCTTTGAATACAACCGCATCAGCGACTTCGTGCAGGG
CTATCCTTCAAAGGTCCATGTGCTGCCCCGGCCGCTAGAAAGCACAGGCGCCGTGGTGTATGCG
GGGAGCCTCTATTTCCAGGGCGCTGAGTCTAGAAGCGTGATCAGGTACGAGCTGAATACTGAGG
CAGTGAAGGCTAAGAAGGAAATCCCTGGAGCTGGCTACCATGGACAGTTCCCATATTCTTGGGG
CGGCTACACAGACATTGACTTGGCTGTAGATGAGAGCGGCCTATGGGTCATTTACAGCACCGAA
GAGGCCAAAGGCGCCATTGTCCTCTCCCAGCTGAACCCAGAGAATCTGGAACTTGAACGAACCT
GGGAGACTAACATCCGTAAGCAGTCAGTCGCCAACGCCTTTGTCATCTGTGGCACCTTGTACAC
CATCAGCAGCTACTCCTCAAACGACGCCACTGTCAACTTCGCTTATGACACAGCCACAGGGAGC
AGCAAGAGCCTGACCATCCCGTTCAAGAACCGCTACAAATACACCAGCATGATTGACTACAACC
CCTCAGAGAGGAAGCTATTTGCCTGGGACAACTTCAACATGGTCACCTACGACATCAAGCTCTC
CAAGATGTGAGAAGTTCCAGGCCTCACCAGCACAGGCAAAAGATCATGACATCCAGGGCCCTGA
AGGGGATCAGAGTGAAGGAGAGCCAGCCAGCCAGGCCCACGTTTCTCTCTGCTTTCCAGCTTTC
ACTAACCTAGGAGACTGTGTGTGCTCACCATCGACCACACAAGGACAGCAGTCTGCAGGCTTAG
ACAGCTTCATGCTATGACAGGTATTCTTTTCTTCTATCAGCTTGGGAAGGACTGTTTATCCAAA
AGAGTCGAAGTTTTCTGGCAATTTAGGGAAAGAGATACAAGGCCTAGTAATTTCTTTATGAAAT
CCTTGCTCTTGCAATTTGCATGGTTCCCATAGGCCATGCTCAAAAGCAGCCCTTCTAAAGGAAG
AGGGAAAGCCAGGATTGAACGTATATGTAAGGTGTGTTTGATATGATTAGCTGCATGATTCAGA
TACAACTCAGCTGGGCATTATATAACCCGTTGCCCTGTGAAATAAAGGCATCTCACCACA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005374904	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000017411
	ENSCLAP00000017411.1

RefSeq Acc Id:

XP_005374904 ⟸ XM_005374847

- UniProtKB:

A0A8C2VNS9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPAVQLLLLACLVWGAGARAAQLRKANDRSGRCQYTFSVASPNESSCPEQGQAMAAIQDLQRDS
STQHAELESTKARLSSLESLLHRLNLDQVAGPQETQEGPQRQVDALRRDRDRLETQARELEVAY
SNLLRDKSALEEEKRRLGQENEELARRLESSLQEAARLRRGQCLQARVPSQDILPGAREVSQWN
LDSLAFQELKSELTEVPASGILKESPSDRPRTEEGNNGCGQLVWVGEPVTLRTAETITGKYGVW
MRDPKPTYPYTRETTWRIDTVGVDIRQVFEYNRISDFVQGYPSKVHVLPRPLESTGAVVYAGSL
YFQGAESRSVIRYELNTEAVKAKKEIPGAGYHGQFPYSWGGYTDIDLAVDESGLWVIYSTEEAK
GAIVLSQLNPENLELERTWETNIRKQSVANAFVICGTLYTISSYSSNDATVNFAYDTATGSSKS
LTIPFKNRYKYTSMIDYNPSERKLFAWDNFNMVTYDIKLSKM

hide sequence

Ensembl Acc Id:

ENSCLAP00000017411 ⟸ ENSCLAT00000017581

Protein Domains

Olfactomedin-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011961	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000017581	ENTREZGENE
	ENSCLAT00000017581.1	UniProtKB/TrEMBL
InterPro	Olfac-like_dom	UniProtKB/TrEMBL
	Olfactomedin-like_domain	UniProtKB/TrEMBL
NCBI Gene	Myoc	ENTREZGENE
PANTHER	OLFACTOMEDIN-RELATED	UniProtKB/TrEMBL
	PTHR23192:SF33	UniProtKB/TrEMBL
Pfam	OLF	UniProtKB/TrEMBL
PROSITE	OLF	UniProtKB/TrEMBL
SMART	OLF	UniProtKB/TrEMBL
UniProt	A0A8C2VNS9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Myoc	myocilin		myocilin, trabecular meshwork inducible glucocorticoid response	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM