Rab1b (RAB1B, member RAS oncogene family)

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Gene: Rab1b (RAB1B, member RAS oncogene family) Chinchilla lanigera

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Symbol:

Rab1b

Name:

RAB1B, member RAS oncogene family

RGD ID:

8711447

Description:

ENCODES a protein that exhibits GTP binding (ortholog); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); establishment of endothelial intestinal barrier (ortholog); Golgi organization (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autosomal recessive cutis laxa type IB (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN endoplasmic reticulum-Golgi intermediate compartment (ortholog); Golgi apparatus (ortholog); phagophore assembly site membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras-related protein Rab-1B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	19,039,632 - 19,047,088 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	19,039,741 - 19,047,088 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 3 (ISO)

autosomal recessive cutis laxa type IB (ISO)

Bardet-Biedl syndrome (ISO)

glycogen storage disease V (ISO)

intellectual disability (ISO)

Myocardial Ischemia (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum to Golgi vesicle-mediated transport (ISO)

establishment of endothelial intestinal barrier (ISO)

Golgi organization (ISO)

positive regulation of glycoprotein metabolic process (ISO)

regulation of autophagosome assembly (ISO)

Cellular Component

endoplasmic reticulum-Golgi intermediate compartment (ISO)

Golgi apparatus (ISO)

phagophore assembly site membrane (ISO)

synapse (ISO)

Molecular Function

GTP binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Rab1b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	19,039,632 - 19,047,088 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	19,039,741 - 19,047,088 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAB1B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	66,268,639 - 66,277,492 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	66,268,590 - 66,277,492 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	66,036,110 - 66,044,963 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	65,792,632 - 65,801,539 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	65,792,680 - 65,801,539	NCBI
Cytogenetic Map	11	q13.2	NCBI
HuRef	11	62,361,564 - 62,370,459 (+)	NCBI		HuRef
CHM1_1	11	65,920,155 - 65,929,064 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	66,262,312 - 66,271,155 (+)	NCBI		T2T-CHM13v2.0

Rab1b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	5,149,235 - 5,157,024 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	5,149,233 - 5,157,100 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	5,099,207 - 5,106,996 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	5,099,205 - 5,107,072 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	5,099,207 - 5,106,996 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	5,099,207 - 5,106,996 (-)	NCBI		MGSCv36	mm8
Celera	19	4,968,413 - 4,976,202 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	4.25	NCBI

Rab1b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	211,835,133 - 211,843,408 (-)	NCBI		GRCr8
mRatBN7.2	1	202,405,759 - 202,413,850 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	50,857,916 - 50,859,762 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	202,405,759 - 202,413,868 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	210,758,818 - 210,766,910 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	217,851,200 - 217,859,291 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	210,542,234 - 210,550,325 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	220,483,529 - 220,491,469 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	220,480,834 - 220,491,469 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	227,414,583 - 227,422,523 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	207,720,833 - 207,727,458 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	199,945,209 - 199,953,183 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

RAB1B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	67,502,340 - 67,511,293 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	68,545,212 - 68,554,168 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	61,634,017 - 61,642,945 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	64,959,957 - 64,968,843 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	64,959,957 - 64,968,843 (+)	Ensembl	panpan1.1		panPan2

RAB1B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	51,026,975 - 51,034,356 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	51,028,013 - 51,034,473 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	49,635,724 - 49,643,112 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	52,065,422 - 52,072,793 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	52,065,422 - 52,072,757 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	51,165,421 - 51,172,793 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	50,739,588 - 50,746,974 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	51,529,728 - 51,537,099 (-)	NCBI		UU_Cfam_GSD_1.0

Rab1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	6,874,909 - 6,881,904 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	3,317,258 - 3,324,213 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	3,317,258 - 3,324,208 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	6,102,354 - 6,116,221 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	6,110,438 - 6,116,443 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	5,185,936 - 5,188,256 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAB1B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	7,989,521 - 7,998,371 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	7,989,101 - 7,998,105 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	105,271,045 - 105,280,234 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rab1b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	20,090,441 - 20,098,913 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	20,091,120 - 20,098,855 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005384425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01022973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01003487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000023203 ⟹ ENSCLAP00000022987

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955422	19,039,632 - 19,047,088 (-)	Ensembl

RefSeq Acc Id:

XM_005384425 ⟹ XP_005384482

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955422	19,039,741 - 19,047,088 (-)	NCBI

Sequence:

show sequence

TGCGGGTGGGGCCTCTGGGGCGGAGCGGCCACCATCTTGGAACGGAGGCGGAGCAGAGCCGACT
GGGAGCGACCGAGCGGGCCTCCGCCGCCGCCATGAACCCCGAATATGACTACCTGTTTAAGCTG
CTTTTGATTGGTGACTCGGGTGTGGGCAAGTCATGCCTGCTTCTGCGGTTCGCTGATGACACAT
ACACGGAGAGCTACATCAGCACCATTGGGGTGGACTTCAAGATCCGAACCATTGAGCTGGATGG
CAAAACCATCAAACTTCAGATTTGGGACACAGCTGGTCAGGAACGGTTTCGGACCATCACTTCC
AGCTACTACCGGGGGGCCCATGGCATCATCGTGGTGTATGATGTCACTGACCAGGAATCCTATG
CCAATGTGAAGCAATGGCTGCAGGAGATTGACCGCTATGCCAGCGAGAATGTCAATAAGCTCCT
GGTGGGCAACAAGAGTGACCTCACCACCAAGAAGGTGGTGGACAACACCACAGCCAAGGAGTTC
GCAGACTCTCTGGGCATCCCCTTCCTAGAGACAAGTGCCAAGAATGCCACCAATGTCGAGCAGG
CTTTCATGACTATGGCTGCTGAGATCAAGAAGCGGATGGGGCCTGGGGCAGCCTCAGGAGGAGA
ACGGCCCAACCTCAAGATCGACAGCACCCCTGTGAAGCCAGCTGGTGGTGGCTGTTGCTAGGAG
GGGCACTTGGGATGGGACAGGAGGGGACACCTTCAGATGATGCCTCTGGAGGGGTCAGGAGATG
CCTCCTTCCTCTCCTGGGCATTTGAGTCTGTGGCTTTGAGGTGTCCTGGGCTCCCCATCTCCTT
CTGGCCCATCTGCCTGCTGTCCTGAGCCCTGGTTCTGTCAGGGTCCCCAAGGGAGGACGTCCAG
GACCTGTGGCAAGGGCAGGGACGGGGGCTGCTCTGCTGCTGCCTCTAGATACCTTGGAAAGATG
CCGCCTTCCTTTGGAACGAGGGCTCCTCTGTCTCCCTTTCCCCGTGTATGCTGCACTGGGTTTC
TCTTTCTCTCGCCCCTTCCCAAGAGCTGAGTCCTCCTTGACCTCTGCTGCCCCTGGCTGCAGTC
AGCACCTTGGGTCAGGACTGTAGCCAGGGGATCCACGGCCTGTGATTGGATCTAGGGCCCTGGG
CTGGACCTCAGGACGGGTATGGGGGGCGCAGAAGTCCAGCAGCCCACCCTTTTCCTCTGCCTCT
ACACCCCTACACTCACAGCTCAAGCCGTCCAGCTACAGTAGGCTCAGAGCACAGCTAGGGCAGG
TGGGCGGGCAGTTACGCTGGGCCTGTGTCTTGAGCCCAGGGGGAGCCTGCTCCTGCCGTCCCCT
ACCCTGCCAGAGGCAGGCCTGTGTGCTGCCTGCTCACCGTGCCCCTTTGTGCCCGAGGCAGGCG
GAGGCGGAAGGCCCACCGTGCCAGAGGCCAGGCACCAGCCTTAACCCTTACTCTGCCAGCACCC
CTCCTCTTTCCCTGAGGCAGCACATCTGGCTCATTCTTCCTCTCATTGCTTAGAGCCTAAGGGG
GCAGAGCCTCATCCCTGCCTCTATTCTGGGGAATGTGGGTGCACCCCAGGACTGGGGGCTTCTT
TGCTCACCCTCTACCCACCCAGGATCCTGGCCCTCTGCCCTCTGGCACAGCTTCTTCCTGCGGA
AAGCAAACCTGGTCTCTACCTAAGAAGCCATGTCCCTGTGCTGTCTCTTGTCTGTCCCAACCAC
ACCCTGCCCCCTCTCCAGCTTGTATTTAAATCCCTGGGCCACCCCTTTGGGGCCCTCCCAGGTT
CCCCTCTGGTGTCATGTCGGGCATTTTGCAAGGAAAAGCCACTTGGGGAAAAATGGAAAAGGAC
AACAAAACAATAAATTTCCACTGGCCCTTGGAGGAGCCGAGGGTTTTTGCAAGGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005384482	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021580.1
	ENSCLAP00000022987
	ENSCLAP00000022987.1

RefSeq Acc Id:

XP_005384482 ⟸ XM_005384425

- UniProtKB:

A0A8C2YTW4 (UniProtKB/TrEMBL), A0A8C2VWM7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDT
AGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTK
KVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTP
VKPAGGGCC

hide sequence

Ensembl Acc Id:

ENSCLAP00000022987 ⟸ ENSCLAT00000023203

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014766	UniProtKB/TrEMBL
	ENSCLAG00000015776	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021783.1	UniProtKB/TrEMBL
	ENSCLAT00000023203	ENTREZGENE
	ENSCLAT00000023203.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Rab	UniProtKB/TrEMBL
	Sigma_54_int_dom_ATP-bd_1	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
NCBI Gene	Rab1b	ENTREZGENE
PANTHER	LD21953P	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB-1B	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	ARF	UniProtKB/TrEMBL
	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
	SIGMA54_INTERACT_1	UniProtKB/TrEMBL
SMART	ARF	UniProtKB/TrEMBL
	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8C2VWM7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YTW4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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