Rab1b (RAB1B, member RAS oncogene family) - Rat Genome Database

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Gene: Rab1b (RAB1B, member RAS oncogene family) Mus musculus
Analyze
Symbol: Rab1b
Name: RAB1B, member RAS oncogene family
RGD ID: 1553174
MGI Page MGI
Description: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in several processes, including autophagosome assembly; endoplasmic reticulum to Golgi vesicle-mediated transport; and regulation of autophagosome assembly. Predicted to act upstream of or within autophagy and protein transport. Located in endoplasmic reticulum-Golgi intermediate compartment. Is expressed in diaphragm. Orthologous to human RAB1B (RAB1B, member RAS oncogene family).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110011F09Rik; ras-related protein Rab-1B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,149,235 - 5,157,024 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,149,233 - 5,157,100 (-)EnsemblGRCm39 Ensembl
GRCm38195,099,207 - 5,106,996 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,099,205 - 5,107,072 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,099,207 - 5,106,996 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,099,207 - 5,106,996 (-)NCBIMGSCv36mm8
Celera194,968,413 - 4,976,202 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7642711   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11773082   PMID:11856727   PMID:12477932   PMID:12578829   PMID:14610273   PMID:15489334   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16923123   PMID:17967808   PMID:18614015   PMID:18799693   PMID:18842593   PMID:20059953   PMID:21187406   PMID:21873635   PMID:22794259   PMID:24457600  
PMID:28378742   PMID:28520221   PMID:30068389   PMID:30550785   PMID:32968282   PMID:33898333   PMID:36417873   PMID:36808153  


Genomics

Comparative Map Data
Rab1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,149,235 - 5,157,024 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,149,233 - 5,157,100 (-)EnsemblGRCm39 Ensembl
GRCm38195,099,207 - 5,106,996 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,099,205 - 5,107,072 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,099,207 - 5,106,996 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,099,207 - 5,106,996 (-)NCBIMGSCv36mm8
Celera194,968,413 - 4,976,202 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.25NCBI
RAB1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381166,268,639 - 66,277,492 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1166,268,590 - 66,277,492 (+)EnsemblGRCh38hg38GRCh38
GRCh371166,036,110 - 66,044,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,792,632 - 65,801,539 (+)NCBINCBI36Build 36hg18NCBI36
Build 341165,792,680 - 65,801,539NCBI
Cytogenetic Map11q13.2NCBI
HuRef1162,361,564 - 62,370,459 (+)NCBIHuRef
CHM1_11165,920,155 - 65,929,064 (+)NCBICHM1_1
T2T-CHM13v2.01166,262,312 - 66,271,155 (+)NCBIT2T-CHM13v2.0
Rab1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,835,133 - 211,843,408 (-)NCBIGRCr8
mRatBN7.21202,405,759 - 202,413,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,857,916 - 50,859,762 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1202,405,759 - 202,413,868 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,758,818 - 210,766,910 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01217,851,200 - 217,859,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,542,234 - 210,550,325 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,483,529 - 220,491,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,480,834 - 220,491,469 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,414,583 - 227,422,523 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41207,720,833 - 207,727,458 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1199,945,209 - 199,953,183 (-)NCBICelera
Cytogenetic Map1q43NCBI
Rab1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,039,632 - 19,047,088 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,039,741 - 19,047,088 (-)NCBIChiLan1.0ChiLan1.0
RAB1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2967,502,340 - 67,511,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11168,545,212 - 68,554,168 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,634,017 - 61,642,945 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,959,957 - 64,968,843 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,959,957 - 64,968,843 (+)Ensemblpanpan1.1panPan2
RAB1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,026,975 - 51,034,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,028,013 - 51,034,473 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,635,724 - 49,643,112 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,065,422 - 52,072,793 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,065,422 - 52,072,757 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,165,421 - 51,172,793 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01850,739,588 - 50,746,974 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,529,728 - 51,537,099 (-)NCBIUU_Cfam_GSD_1.0
Rab1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049476,874,909 - 6,881,904 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,317,258 - 3,324,213 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,317,258 - 3,324,208 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,102,354 - 6,116,221 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,110,438 - 6,116,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,185,936 - 5,188,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.117,989,521 - 7,998,371 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl17,989,101 - 7,998,105 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,271,045 - 105,280,234 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,090,441 - 20,098,913 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,091,120 - 20,098,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rab1b
217 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:558
Count of miRNA genes:368
Interacting mature miRNAs:396
Transcripts:ENSMUST00000025804
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950648178957825Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse

Markers in Region
AW212649  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,108,020 - 5,108,128UniSTSGRCm38
MGSCv37195,108,020 - 5,108,128UniSTSGRCm37
Celera194,977,319 - 4,977,427UniSTS
Cytogenetic Map19AUniSTS
cM Map199.0UniSTS
Whitehead/MRC_RH1959.81UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_029576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB232584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000025804   ⟹   ENSMUSP00000025804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,149,233 - 5,157,100 (-)Ensembl
GRCm38.p6 Ensembl195,099,205 - 5,107,072 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236149   ⟹   ENSMUSP00000158567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,150,416 - 5,157,033 (-)Ensembl
GRCm38.p6 Ensembl195,100,388 - 5,107,005 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237201   ⟹   ENSMUSP00000157487
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,150,437 - 5,156,273 (-)Ensembl
GRCm38.p6 Ensembl195,100,409 - 5,106,245 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237438   ⟹   ENSMUSP00000157879
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,150,336 - 5,157,004 (-)Ensembl
GRCm38.p6 Ensembl195,100,308 - 5,106,976 (-)Ensembl
RefSeq Acc Id: NM_029576   ⟹   NP_083852
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,149,235 - 5,157,024 (-)NCBI
GRCm38195,099,207 - 5,106,996 (-)NCBI
MGSCv37195,099,207 - 5,106,996 (-)RGD
Celera194,968,413 - 4,976,202 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_083852   ⟸   NM_029576
- UniProtKB: Q3U0N1 (UniProtKB/Swiss-Prot),   Q9D1G1 (UniProtKB/Swiss-Prot),   Q0PD66 (UniProtKB/TrEMBL),   Q3V3C2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000157487   ⟸   ENSMUST00000237201
RefSeq Acc Id: ENSMUSP00000157879   ⟸   ENSMUST00000237438
RefSeq Acc Id: ENSMUSP00000025804   ⟸   ENSMUST00000025804
RefSeq Acc Id: ENSMUSP00000158567   ⟸   ENSMUST00000236149

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D1G1-F1-model_v2 AlphaFold Q9D1G1 1-201 view protein structure

Promoters
RGD ID:6847584
Promoter ID:MM_ACW:25828
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6
Transcripts:RAB1B.ASEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,105,651 - 5,106,151 (-)MPROMDB
RGD ID:6830350
Promoter ID:MM_KWN:26055
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000025804
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,106,526 - 5,107,102 (-)MPROMDB
RGD ID:13678492
Promoter ID:EPDNEW_M23395
Type:initiation region
Name:Rab1b_1
Description:Mus musculus RAB1B, member RAS oncogene family , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38195,106,979 - 5,107,039EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923558 AgrOrtholog
Ensembl Genes ENSMUSG00000024870 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025804 ENTREZGENE
  ENSMUST00000025804.7 UniProtKB/Swiss-Prot
  ENSMUST00000236149.2 UniProtKB/TrEMBL
  ENSMUST00000237201.2 UniProtKB/TrEMBL
  ENSMUST00000237438.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:76308 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1923558 ENTREZGENE
NCBI Gene 76308 ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-1B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rab1b PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494B945_MOUSE UniProtKB/TrEMBL
  A0A494BA38_MOUSE UniProtKB/TrEMBL
  A0A494BBL7_MOUSE UniProtKB/TrEMBL
  Q0PD66 ENTREZGENE, UniProtKB/TrEMBL
  Q3U0N1 ENTREZGENE
  Q3V3C2 ENTREZGENE, UniProtKB/TrEMBL
  Q9D1G1 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3U0N1 UniProtKB/Swiss-Prot