RAB1B (RAB1B, member RAS oncogene family) - Rat Genome Database

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Gene: RAB1B (RAB1B, member RAS oncogene family) Chlorocebus sabaeus
Analyze
Symbol: RAB1B
Name: RAB1B, member RAS oncogene family
RGD ID: 18585876
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); INVOLVED IN establishment of endothelial intestinal barrier (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autosomal recessive cutis laxa type IB (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN endoplasmic reticulum-Golgi intermediate compartment (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-1B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.117,989,521 - 7,998,371 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl17,989,101 - 7,998,105 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,271,045 - 105,280,234 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RAB1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.117,989,521 - 7,998,371 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl17,989,101 - 7,998,105 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,271,045 - 105,280,234 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RAB1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381166,268,639 - 66,277,492 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1166,268,590 - 66,277,492 (+)EnsemblGRCh38hg38GRCh38
GRCh371166,036,110 - 66,044,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,792,632 - 65,801,539 (+)NCBINCBI36Build 36hg18NCBI36
Build 341165,792,680 - 65,801,539NCBI
Cytogenetic Map11q13.2NCBI
HuRef1162,361,564 - 62,370,459 (+)NCBIHuRef
CHM1_11165,920,155 - 65,929,064 (+)NCBICHM1_1
T2T-CHM13v2.01166,262,312 - 66,271,155 (+)NCBIT2T-CHM13v2.0
Rab1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,149,235 - 5,157,024 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,149,233 - 5,157,100 (-)EnsemblGRCm39 Ensembl
GRCm38195,099,207 - 5,106,996 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,099,205 - 5,107,072 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,099,207 - 5,106,996 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,099,207 - 5,106,996 (-)NCBIMGSCv36mm8
Celera194,968,413 - 4,976,202 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.25NCBI
Rab1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,835,133 - 211,843,408 (-)NCBIGRCr8
mRatBN7.21202,405,759 - 202,413,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,857,916 - 50,859,762 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1202,405,759 - 202,413,868 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,758,818 - 210,766,910 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01217,851,200 - 217,859,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,542,234 - 210,550,325 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,483,529 - 220,491,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,480,834 - 220,491,469 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,414,583 - 227,422,523 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41207,720,833 - 207,727,458 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1199,945,209 - 199,953,183 (-)NCBICelera
Cytogenetic Map1q43NCBI
Rab1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,039,632 - 19,047,088 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,039,741 - 19,047,088 (-)NCBIChiLan1.0ChiLan1.0
RAB1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2967,502,340 - 67,511,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11168,545,212 - 68,554,168 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,634,017 - 61,642,945 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,959,957 - 64,968,843 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,959,957 - 64,968,843 (+)Ensemblpanpan1.1panPan2
RAB1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,026,975 - 51,034,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,028,013 - 51,034,473 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,635,724 - 49,643,112 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01852,065,422 - 52,072,793 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,065,422 - 52,072,757 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,165,421 - 51,172,793 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01850,739,588 - 50,746,974 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,529,728 - 51,537,099 (-)NCBIUU_Cfam_GSD_1.0
Rab1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049476,874,909 - 6,881,904 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,317,258 - 3,324,213 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,317,258 - 3,324,208 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,102,354 - 6,116,221 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,110,438 - 6,116,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,185,936 - 5,188,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rab1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,090,441 - 20,098,913 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476720,091,120 - 20,098,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 13 60
Low 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000006197   ⟹   ENSCSAP00000004405
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl17,989,101 - 7,998,105 (-)Ensembl
RefSeq Acc Id: XM_007976931   ⟹   XP_007975122
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.117,989,521 - 7,997,875 (-)NCBI
Vero_WHO_p1.0NW_023666038105,271,045 - 105,279,548 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007977020   ⟹   XP_007975211
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.117,989,521 - 7,998,371 (-)NCBI
Vero_WHO_p1.0NW_023666038105,271,045 - 105,280,234 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037999051   ⟹   XP_037854979
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038105,271,045 - 105,279,692 (-)NCBI
RefSeq Acc Id: XM_037999052   ⟹   XP_037854980
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038105,271,045 - 105,280,222 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007975122 (Get FASTA)   NCBI Sequence Viewer  
  XP_007975211 (Get FASTA)   NCBI Sequence Viewer  
  XP_037854979 (Get FASTA)   NCBI Sequence Viewer  
  XP_037854980 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004405
  ENSCSAP00000004405.1
Reference Protein Sequences
RefSeq Acc Id: XP_007975211   ⟸   XM_007977020
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007975122   ⟸   XM_007976931
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R716 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000004405   ⟸   ENSCSAT00000006197
RefSeq Acc Id: XP_037854980   ⟸   XM_037999052
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037854979   ⟸   XM_037999051
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006197.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene RAB1B ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-1B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9R716 ENTREZGENE, UniProtKB/TrEMBL