Sost (sclerostin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Sost (sclerostin) Mus musculus
Analyze
Symbol: Sost
Name: sclerostin
RGD ID: 737335
MGI Page MGI
Description: Predicted to enable several functions, including BMP binding activity; DNA-binding transcription factor binding activity; and carbohydrate binding activity. Acts upstream of or within negative regulation of ossification; negative regulation of signal transduction; and ossification. Predicted to be located in Golgi apparatus. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space. Is expressed in several structures, including arterial system; jaw; limb bud; nervous system; and skeleton. Used to study SOST-related sclerosing bone dysplasia and sclerosteosis 1. Human ortholog(s) of this gene implicated in autosomal dominant craniodiaphyseal dysplasia; sclerosteosis; and sclerosteosis 1. Orthologous to human SOST (sclerostin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 5430411E23Rik
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,853,284 - 101,857,841 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,853,284 - 101,857,841 (-)EnsemblGRCm39 Ensembl
GRCm3811101,962,458 - 101,967,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,962,458 - 101,967,015 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,823,772 - 101,828,329 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,778,626 - 101,783,105 (-)NCBIMGSCv36mm8
Celera11113,667,734 - 113,672,291 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1165.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Brunkow ME, etal., Am J Hum Genet 2001 Mar;68(3):577-89.
2. Secreted and transmembrane wnt inhibitors and activators. Cruciat CM and Niehrs C, Cold Spring Harb Perspect Biol. 2013 Mar 1;5(3):a015081. doi: 10.1101/cshperspect.a015081.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11544199   PMID:12412008   PMID:12477932   PMID:12702725   PMID:14633986   PMID:15199066   PMID:15217980   PMID:15545262   PMID:15946907  
PMID:15965026   PMID:16081646   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17002572   PMID:17032150   PMID:17185821   PMID:17185824   PMID:17195180   PMID:17696759   PMID:18089564  
PMID:18269310   PMID:18351662   PMID:18521528   PMID:18927151   PMID:19075223   PMID:19166819   PMID:19389359   PMID:19419300   PMID:19594304   PMID:19837663   PMID:19874086   PMID:19896444  
PMID:19936252   PMID:20359476   PMID:20562862   PMID:20816666   PMID:20952383   PMID:21079361   PMID:21267068   PMID:21285247   PMID:21312267   PMID:21329818   PMID:21677750   PMID:21703370  
PMID:21855668   PMID:21873635   PMID:21890008   PMID:21945937   PMID:21952235   PMID:22075208   PMID:22434688   PMID:22560000   PMID:22735261   PMID:22768243   PMID:22886088   PMID:22886599  
PMID:22927401   PMID:23044658   PMID:23171658   PMID:23233270   PMID:23308287   PMID:23362266   PMID:23494985   PMID:23530237   PMID:23638027   PMID:23737439   PMID:23776575   PMID:23782749  
PMID:23901037   PMID:23918385   PMID:23994639   PMID:24131868   PMID:24211207   PMID:24225945   PMID:24312339   PMID:24432364   PMID:24446199   PMID:24699186   PMID:24753092   PMID:24780398  
PMID:24789067   PMID:24821585   PMID:24876121   PMID:24917674   PMID:24949665   PMID:25046534   PMID:25056116   PMID:25271055   PMID:25331958   PMID:25404300   PMID:25445453   PMID:25640331  
PMID:25660312   PMID:25721666   PMID:25757567   PMID:25808845   PMID:25847683   PMID:25953900   PMID:26094741   PMID:26218891   PMID:26273529   PMID:26337453   PMID:26361013   PMID:26456319  
PMID:26553151   PMID:26608966   PMID:26713363   PMID:26763740   PMID:26845353   PMID:26925839   PMID:27085457   PMID:27089204   PMID:27163932   PMID:27188231   PMID:27349550   PMID:27402532  
PMID:27524798   PMID:27528549   PMID:27601226   PMID:27653320   PMID:27759007   PMID:27804995   PMID:28062506   PMID:28081119   PMID:28327634   PMID:28460416   PMID:28529307   PMID:28543818  
PMID:28571484   PMID:28794403   PMID:28842678   PMID:28880886   PMID:29024567   PMID:29149200   PMID:29162742   PMID:29174564   PMID:29175269   PMID:29229807   PMID:29349060   PMID:29351359  
PMID:29377313   PMID:29561836   PMID:29734465   PMID:29750826   PMID:29845410   PMID:29875318   PMID:29967369   PMID:30041240   PMID:30071108   PMID:30172741   PMID:30266511   PMID:30283358  
PMID:30622831   PMID:30689868   PMID:30735798   PMID:30837894   PMID:30842262   PMID:31088250   PMID:31202927   PMID:31292298   PMID:31437568   PMID:31480885   PMID:31501981   PMID:31505764  
PMID:31584963   PMID:31708103   PMID:31828128   PMID:31970653   PMID:31975377   PMID:32134561   PMID:32652075   PMID:32792620   PMID:32976505   PMID:33078679   PMID:33148174   PMID:33339872  
PMID:33436499   PMID:33479403   PMID:33767359   PMID:33907818   PMID:33996804   PMID:34091985   PMID:34172578   PMID:34254395   PMID:34260913   PMID:34321664   PMID:34376651   PMID:34421825  
PMID:34502021   PMID:34606641   PMID:35099616   PMID:35169297   PMID:35278242   PMID:35381389   PMID:35472633   PMID:36087347   PMID:36240434   PMID:36462771   PMID:36606556   PMID:36840409  
PMID:36891756   PMID:36973504   PMID:37121919   PMID:37154419   PMID:37534168   PMID:37709732   PMID:38042445   PMID:38274045   PMID:38910391   PMID:39074536  


Genomics

Comparative Map Data
Sost
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,853,284 - 101,857,841 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,853,284 - 101,857,841 (-)EnsemblGRCm39 Ensembl
GRCm3811101,962,458 - 101,967,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,962,458 - 101,967,015 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,823,772 - 101,828,329 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,778,626 - 101,783,105 (-)NCBIMGSCv36mm8
Celera11113,667,734 - 113,672,291 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1165.48NCBI
SOST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381743,753,738 - 43,758,791 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1743,753,738 - 43,758,791 (-)EnsemblGRCh38hg38GRCh38
GRCh371741,831,106 - 41,836,159 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361739,186,625 - 39,191,682 (-)NCBINCBI36Build 36hg18NCBI36
Build 341739,186,624 - 39,191,682NCBI
Celera1738,539,106 - 38,544,164 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1737,595,207 - 37,600,265 (-)NCBIHuRef
CHM1_11742,066,723 - 42,071,781 (-)NCBICHM1_1
T2T-CHM13v2.01744,606,296 - 44,611,349 (-)NCBIT2T-CHM13v2.0
Sost
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81087,412,722 - 87,415,766 (-)NCBIGRCr8
mRatBN7.21086,912,517 - 86,915,561 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,911,517 - 86,915,561 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,941,934 - 91,944,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01091,417,549 - 91,420,598 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,810,861 - 86,813,910 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,897,087 - 89,900,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,897,087 - 89,900,131 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,689,512 - 89,692,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,023,712 - 91,026,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11091,038,081 - 91,041,129 (-)NCBI
Celera1085,631,705 - 85,634,749 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Sost
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545117,054,939 - 17,058,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545117,054,939 - 17,058,027 (-)NCBIChiLan1.0ChiLan1.0
SOST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21921,149,763 - 21,155,219 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11723,114,052 - 23,119,508 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01713,639,088 - 13,644,152 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11713,804,374 - 13,809,432 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1713,804,374 - 13,809,432 (+)Ensemblpanpan1.1panPan2
SOST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1919,538,713 - 19,544,650 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl919,539,435 - 19,544,651 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha918,928,494 - 18,933,390 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,234,523 - 20,239,413 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,234,719 - 20,239,089 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,087,300 - 19,092,190 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,270,262 - 19,275,387 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,415,616 - 19,420,514 (+)NCBIUU_Cfam_GSD_1.0
Sost
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560218,876,390 - 18,881,316 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936541313,287 - 318,176 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936541313,308 - 318,109 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,355,234 - 19,360,352 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11219,354,912 - 19,360,348 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21219,588,864 - 19,592,789 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SOST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11662,649,053 - 62,656,192 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1662,651,146 - 62,654,570 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607733,418,277 - 33,423,353 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sost
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,006,813 - 1,008,685 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,006,811 - 1,009,437 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sost
207 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:569
Count of miRNA genes:351
Interacting mature miRNAs:419
Transcripts:ENSMUST00000001534
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
14700693Ppiq12_mprepulse inhibition QTL 12 (mouse)11101504820114472363Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
14700694Ppiq13_mprepulse inhibition QTL 13 (mouse)11101504820114472363Mouse
14700695Ppiq14_mprepulse inhibition QTL 14 (mouse)11101504820114472363Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
14700696Ppiq15_mprepulse inhibition QTL 15 (mouse)11101504820114472363Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000001534   ⟹   ENSMUSP00000001534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11101,853,284 - 101,857,841 (-)Ensembl
GRCm38.p6 Ensembl11101,962,458 - 101,967,015 (-)Ensembl
RefSeq Acc Id: NM_024449   ⟹   NP_077769
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,853,284 - 101,857,841 (-)NCBI
GRCm3811101,962,458 - 101,967,015 (-)ENTREZGENE
MGSCv3711101,823,772 - 101,828,329 (-)RGD
Celera11113,667,734 - 113,672,291 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534376   ⟹   XP_006534439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911101,853,287 - 101,855,438 (-)NCBI
GRCm3811101,962,461 - 101,964,601 (-)NCBI
Sequence:
RefSeq Acc Id: NP_077769   ⟸   NM_024449
- Peptide Label: precursor
- UniProtKB: Q9D3L7 (UniProtKB/Swiss-Prot),   Q99P68 (UniProtKB/Swiss-Prot),   B2RQA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006534439   ⟸   XM_006534376
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000001534   ⟸   ENSMUST00000001534
Protein Domains
CTCK

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99P68-F1-model_v2 AlphaFold Q99P68 1-211 view protein structure

Promoters
RGD ID:8676840
Promoter ID:EPDNEW_M16450
Type:single initiation site
Name:Sost_1
Description:Mus musculus sclerostin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811101,967,015 - 101,967,075EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921749 AgrOrtholog
Ensembl Genes ENSMUSG00000001494 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000001534 ENTREZGENE
  ENSMUST00000001534.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot
  Sclerostin/SOSTDC1 UniProtKB/Swiss-Prot
KEGG Report mmu:74499 UniProtKB/Swiss-Prot
MGD MGI:1921749 ENTREZGENE
NCBI Gene 74499 ENTREZGENE
PANTHER PTHR14903 UniProtKB/Swiss-Prot
  PTHR14903:SF4 UniProtKB/Swiss-Prot
Pfam Sclerostin UniProtKB/Swiss-Prot
PhenoGen Sost PhenoGen
UniProt B2RQA5 ENTREZGENE
  Q99P68 ENTREZGENE
  Q9D3L7 ENTREZGENE
  SOST_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary B2RQA5 UniProtKB/Swiss-Prot
  Q9D3L7 UniProtKB/Swiss-Prot