Vom2r31 (vomeronasal 2 receptor, 31) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Vom2r31 (vomeronasal 2 receptor, 31) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r31
Name: vomeronasal 2 receptor, 31
RGD ID: 708412
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane; INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC286985; putative pheromone receptor (Go-VN7); vomeronasal 2 receptor 31
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8180,255,245 - 80,283,462 (+)NCBIGRCr8
mRatBN7.2171,183,055 - 71,211,273 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl170,831,826 - 70,896,261 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl171,185,371 - 71,211,267 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx176,573,782 - 76,599,630 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0185,138,129 - 85,163,979 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,261,527 - 78,293,826 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0174,975,364 - 75,001,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl174,975,364 - 75,001,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0173,554,037 - 73,579,885 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4170,654,662 - 70,680,510NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1170,732,772 - 70,758,621NCBI
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r31Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of VOM2R31 mRNACTDPMID:28959563
Vom2r31Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of VOM2R31 mRNACTDPMID:16483693
Vom2r31Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of VOM2R31 mRNACTDPMID:30816183
Vom2r31RatCuprizon decreases expressionEXP 6480464Cuprizone results in decreased expression of VOM2R31 mRNACTDPMID:27523638
Vom2r31Ratfenvalerate increases expressionEXP 6480464fenvalerate results in increased expression of VOM2R31 mRNACTDPMID:30307764
Vom2r31Ratmethamphetamine decreases expressionEXP 6480464Methamphetamine results in decreased expression of VOM2R31 mRNACTDPMID:19564919


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r31RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Vom2r31RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Vom2r31Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r31Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Vom2r31Ratmembrane located_inIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Vom2r31Ratplasma membrane is_active_inIBAMGI:2429498 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Vom2r31Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Vom2r31Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r31RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Vom2r31RatG protein-coupled receptor activity enablesIBAMGI:2429498 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Vom2r31RatG protein-coupled receptor activity enablesIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution. Herrada G and Dulac C, Cell 1997 Aug 22;90(4):763-73.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:17382427  



.

.
Variants in Vom2r31
1288 total Variants

Predicted Target Of
Summary Value
Count of predictions:408
Count of miRNA genes:243
Interacting mature miRNAs:282
Transcripts:ENSRNOT00000047147
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat

1 to 10 of 46 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 9 14 29 41 43 15 25 15 3 95 53 16 11 29 28



Ensembl Acc Id: ENSRNOT00000040441   ⟹   ENSRNOP00000050611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl170,831,826 - 70,856,007 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000047147   ⟹   ENSRNOP00000051358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl171,185,371 - 71,211,267 (+)Ensembl
Rnor_6.0 Ensembl174,975,364 - 75,001,206 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080755   ⟹   ENSRNOP00000069672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl170,831,826 - 70,856,007 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090708   ⟹   ENSRNOP00000069490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl170,831,826 - 70,896,261 (-)Ensembl
Rnor_6.0 Ensembl174,975,388 - 74,999,726 (+)Ensembl
RefSeq Acc Id: NM_173319   ⟹   NP_775441
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8180,257,616 - 80,283,462 (+)NCBI
mRatBN7.2171,185,427 - 71,211,273 (+)NCBI
Rnor_6.0174,975,364 - 75,001,212 (+)NCBI
Rnor_5.0173,554,037 - 73,579,885 (-)NCBI
RGSC_v3.4170,654,662 - 70,680,510 (+)RGD
Celera165,837,915 - 65,840,154 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102751   ⟹   XP_038958679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8180,255,245 - 80,281,976 (+)NCBI
mRatBN7.2171,183,055 - 71,209,787 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_775441 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958679 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53331 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003660
  ENSRNOP00000050611.6
  ENSRNOP00000051358
  ENSRNOP00000051358.4
  ENSRNOP00000069490.2
  ENSRNOP00000069672.2
1 to 9 of 9 rows
RefSeq Acc Id: NP_775441   ⟸   NM_173319
- Peptide Label: precursor
- UniProtKB: Q9QWK0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069490   ⟸   ENSRNOT00000090708
Ensembl Acc Id: ENSRNOP00000051358   ⟸   ENSRNOT00000047147
RefSeq Acc Id: XP_038958679   ⟸   XM_039102751
- Peptide Label: isoform X1
- UniProtKB: E9PT57 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000050611   ⟸   ENSRNOT00000040441
G-protein coupled receptors family 3 profile

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVH8-F1-model_v2 AlphaFold A0A0G2JVH8 1-798 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 40 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-60795 BioCyc
Ensembl Genes ENSRNOG00000031562 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000068273 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003660 ENTREZGENE
  ENSRNOT00000040441.6 UniProtKB/TrEMBL
  ENSRNOT00000047147 ENTREZGENE
  ENSRNOT00000047147.5 UniProtKB/TrEMBL
  ENSRNOT00000080755.2 UniProtKB/TrEMBL
  ENSRNOT00000090708.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  ATPase_P-typ_TM_dom UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report rno:286985 UniProtKB/TrEMBL
NCBI Gene 286985 ENTREZGENE
PANTHER EC2-V2R PHEROMONE RECEPTOR PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR24061 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r31 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031562 RatGTEx
  ENSRNOG00000068273 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
  SSF81665 UniProtKB/TrEMBL
UniProt A0A0G2JVH8_RAT UniProtKB/TrEMBL
  A0A0G2JVY7_RAT UniProtKB/TrEMBL
  D3ZB66_RAT UniProtKB/TrEMBL
  E9PT57 ENTREZGENE, UniProtKB/TrEMBL
  Q9QWK0 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 40 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-23 Vom2r31  vomeronasal 2 receptor, 31    vomeronasal 2 receptor 31  Symbol and Name updated 1299863 APPROVED
2008-05-01 Vom2r31  vomeronasal 2 receptor 31  LOC286985  putative pheromone receptor (Go-VN7)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 LOC286985        Symbol and Name status set to provisional 70820 PROVISIONAL