PDXK (pyridoxal kinase) - Rat Genome Database

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Gene: PDXK (pyridoxal kinase) Homo sapiens
Analyze
Symbol: PDXK
Name: pyridoxal kinase
RGD ID: 30302202
HGNC Page HGNC:8819
Description: Enables several functions, including heterocyclic compound binding activity; metal ion binding activity; and protein homodimerization activity. Involved in pyridoxal 5'-phosphate salvage. Located in nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C21orf124; C21orf97; epididymis secretory sperm binding protein Li 1a; HEL-S-1a; HMSN6C; PKH; PNK; PRED79; pyridoxal (pyridoxine, vitamin B6) kinase; pyridoxamine kinase; pyridoxine kinase; vitamin B6 kinase
RGD Orthologs
Dog
Pig
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,719,129 - 43,762,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,719,094 - 43,762,307 (+)EnsemblGRCh38hg38GRCh38
GRCh372145,139,010 - 45,182,180 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map21q22.3NCBI
HuRef2130,506,765 - 30,550,585 (+)NCBIHuRef
CHM1_12144,699,825 - 44,742,673 (+)NCBICHM1_1
T2T-CHM13v2.02142,074,671 - 42,117,910 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 13 of 13 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHumanautistic disorder  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
PDXKHumancataract 9 multiple types  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Cataract 9 multiple typesClinVarPMID:28492532
PDXKHumanCharcot-Marie-Tooth Disease Type 6C  IAGP (Homo sapiens) more ...8554872ClinVar more ...ClinVarPMID:25741868
PDXKHumanCharcot-Marie-Tooth Disease Type 6C  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: CHARCOT-MARIE-TOOTH DISEASE and TYPE 6CClinVarPMID:25741868 and PMID:31187503
PDXKHumanCharcot-Marie-Tooth Disease Type 6C  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Neuropathy more ...ClinVarPMID:31187503
PDXKHumandevelopmental and epileptic encephalopathy 30  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 30ClinVarPMID:28492532 and PMID:8596935
PDXKHumandevelopmental and epileptic encephalopathy 30  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 30ClinVarPMID:28492532
PDXKHumandevelopmental and epileptic encephalopathy 30  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 30ClinVarPMID:25839329 and PMID:28492532
PDXKHumanhomocystinuria  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: HYPERHOMOCYSTEINEMIA more ...ClinVarPMID:10338090 more ...
PDXKHumanNeurodevelopmental Disorders  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
PDXKHumanprimary ciliary dyskinesia  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Primary ciliary dyskinesiaClinVarPMID:28492532
PDXKHumanprogressive myoclonus epilepsy  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532 and PMID:8596935
PDXKHumanprogressive myoclonus epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532
1 to 13 of 13 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHumanstatus epilepticus  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:19356691
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHumanCharcot-Marie-Tooth Disease Type 6C  IAGP 7240710 OMIM 

1 to 20 of 62 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHuman17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of PDXK mRNACTDPMID:30165855
PDXKHuman17beta-hydroxy-17-methylestra-4,9,11-trien-3-one decreases expressionEXP 6480464Metribolone results in decreased expression of PDXK proteinCTDPMID:17152098
PDXKHuman17beta-hydroxy-17-methylestra-4,9,11-trien-3-one affects splicingEXP 6480464Metribolone affects the splicing of PDXK mRNACTDPMID:17010196
PDXKHuman3,3',5,5'-tetrabromobisphenol A decreases expressionEXP 6480464tetrabromobisphenol A results in decreased expression of PDXK proteinCTDPMID:31675489
PDXKHuman3-isobutyl-1-methyl-7H-xanthine multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDXK mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PDXK mRNACTDPMID:28628672
PDXKHuman4,4'-sulfonyldiphenol decreases methylationEXP 6480464bisphenol S results in decreased methylation of PDXK geneCTDPMID:31601247
PDXKHuman4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of PDXK proteinCTDPMID:34186270
PDXKHuman5-fluorouracil decreases expressionEXP 6480464Fluorouracil results in decreased expression of PDXK mRNACTDPMID:16510598
PDXKHumanactinomycin D multiple interactionsEXP 6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of PDXK proteinCTDPMID:38460933
PDXKHumanaflatoxin B1 decreases methylationEXP 6480464Aflatoxin B1 results in decreased methylation of PDXK intronCTDPMID:30157460
PDXKHumanall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of PDXK mRNACTDPMID:15498508
PDXKHumanall-trans-retinoic acid decreases expressionEXP 6480464Tretinoin results in decreased expression of PDXK proteinCTDPMID:17051635
PDXKHumanarsenous acid decreases response to substanceEXP 6480464PDXK protein results in decreased susceptibility to Arsenic TrioxideCTDPMID:20707922
PDXKHumanbenzene increases expressionEXP 6480464Benzene results in increased expression of PDXK mRNACTDPMID:19162166
PDXKHumanbenzo[a]pyrene increases methylationEXP 6480464Benzo(a)pyrene results in increased methylation of PDXK 3' UTRCTDPMID:27901495
PDXKHumanbenzo[a]pyrene diol epoxide I decreases expressionEXP 64804647 more ...CTDPMID:19150397
PDXKHumanbisphenol A multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PDXK mRNACTDPMID:28628672
PDXKHumanbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of PDXK proteinCTDPMID:34186270
PDXKHumanbisphenol A decreases methylationEXP 6480464bisphenol A results in decreased methylation of PDXK geneCTDPMID:31601247
PDXKHumanBisphenol B increases expressionEXP 6480464bisphenol B results in increased expression of PDXK proteinCTDPMID:34186270

1 to 20 of 62 rows

Biological Process
1 to 9 of 9 rows

  
1 to 9 of 9 rows

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHumancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
PDXKHumancytosol located_inTAS 150520179 ReactomeReactome:R-HSA-964958 more ...
PDXKHumancytosol is_active_inIBAMGI:1351869 more ...150520179 GO_CentralGO_REF:0000033
PDXKHumancytosol located_inIEAUniProtKB-SubCell:SL-0091150520179 UniProtGO_REF:0000044
PDXKHumancytosol located_inHDA 150520179 PMID:16780588UniProtPMID:16780588
PDXKHumancytosol located_inIEAUniProtKB:Q8K183 and ensembl:ENSMUSP00000038540150520179 EnsemblGO_REF:0000107
PDXKHumanextracellular exosome located_inHDA 150520179 PMID:19056867UniProtPMID:19056867
PDXKHumanextracellular region located_inTAS 150520179 ReactomeReactome:R-HSA-6798748 and Reactome:R-HSA-6798749
PDXKHumannucleoplasm located_inIDA 150520179 HPAGO_REF:0000052
PDXKHumannucleus located_inHDA 150520179 PMID:21630459UniProtPMID:21630459
PDXKHumansecretory granule lumen located_inTAS 150520179 ReactomeReactome:R-HSA-6798748
PDXKHumanspecific granule lumen located_inTAS 150520179 ReactomeReactome:R-HSA-6798749
1 to 12 of 12 rows

Molecular Function
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHumanATP binding enablesIDA 150520179 PMID:16600635 and PMID:17766369UniProtPMID:16600635 and PMID:17766369
PDXKHumanATP binding enablesIEAUniProtKB-KW:KW-0067150520179 UniProtGO_REF:0000043
PDXKHumankinase activity enablesIEAUniProtKB-KW:KW-0418150520179 UniProtGO_REF:0000043
PDXKHumanlithium ion binding enablesIDA 150520179 PMID:9252787UniProtPMID:9252787
PDXKHumanmagnesium ion binding enablesIDA 150520179 PMID:17766369UniProtPMID:17766369
PDXKHumanmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
PDXKHumanphosphotransferase activity, alcohol group as acceptor enablesIEAUniProtKB:Q8K183 and ensembl:ENSMUSP00000038540150520179 EnsemblGO_REF:0000107
PDXKHumanpotassium ion binding enablesIDA 150520179 PMID:17766369 and PMID:9252787UniProtPMID:17766369 and PMID:9252787
PDXKHumanprotein homodimerization activity enablesIDA 150520179 PMID:16600635 and PMID:17766369UniProtPMID:16600635 and PMID:17766369
PDXKHumanpyridoxal kinase activity enablesIEAUniProtKB:Q8K183 and ensembl:ENSMUSP00000038540150520179 EnsemblGO_REF:0000107
PDXKHumanpyridoxal kinase activity enablesIBAMGI:1351869 more ...150520179 GO_CentralGO_REF:0000033
PDXKHumanpyridoxal kinase activity enablesIEAInterPro:IPR004625150520179 InterProGO_REF:0000002
PDXKHumanpyridoxal kinase activity enablesIEARHEA:10224150520179 RHEAGO_REF:0000116
PDXKHumanpyridoxal kinase activity enablesIMP 150520179 PMID:31187503UniProtPMID:31187503
PDXKHumanpyridoxal kinase activity enablesIDA 150520179 PMID:10987144 more ...UniProtPMID:10987144 more ...
PDXKHumanpyridoxal kinase activity enablesIEAEC:2.7.1.35150520179 UniProtGO_REF:0000003
PDXKHumanpyridoxal phosphate binding enablesIDA 150520179 PMID:16600635UniProtPMID:16600635
PDXKHumansodium ion binding enablesIDA 150520179 PMID:17766369 and PMID:9252787UniProtPMID:17766369 and PMID:9252787
PDXKHumanzinc ion binding enablesIDA 150520179 PMID:10987144UniProtPMID:10987144
1 to 19 of 19 rows

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PDXKHumanAutism  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
PDXKHumanGeneralized myoclonic seizure  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532
PDXKHumanGeneralized myoclonic seizure  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532 and PMID:8596935
PDXKHumanGeneralized myoclonic seizure  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532
PDXKHumanGeneralized myoclonic seizure  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532
PDXKHumanGeneralized myoclonic seizure  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive myoclonic epilepsyClinVarPMID:28492532 and PMID:8596935
PMID:2009   PMID:6088736   PMID:8125298   PMID:8510562   PMID:9099727   PMID:9252787   PMID:9354586   PMID:10024608   PMID:10830953   PMID:10930737   PMID:10987144   PMID:12477932  
PMID:14702039   PMID:15082224   PMID:15154080   PMID:15161933   PMID:15489334   PMID:16021519   PMID:16344560   PMID:16600635   PMID:16704963   PMID:16780588   PMID:17766369   PMID:18029348  
PMID:19056867   PMID:19086053   PMID:19322201   PMID:19351586   PMID:20035503   PMID:20373357   PMID:20639122   PMID:21145461   PMID:21630459   PMID:21697133   PMID:21873635   PMID:22647618  
PMID:22658674   PMID:22990118   PMID:23376485   PMID:26344197   PMID:26618866   PMID:27542412   PMID:28611215   PMID:29509190   PMID:30652415   PMID:30711629   PMID:30773093   PMID:30833792  
PMID:30948266   PMID:31187503   PMID:31578392   PMID:31586073   PMID:32416067   PMID:32513696   PMID:32696745   PMID:32807901   PMID:33001583   PMID:33545068   PMID:35013556   PMID:35256949  
PMID:35831314   PMID:35987950   PMID:36215168   PMID:36736316   PMID:37317656   PMID:37433992   PMID:37827155  



PDXK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,719,129 - 43,762,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,719,094 - 43,762,307 (+)EnsemblGRCh38hg38GRCh38
GRCh372145,139,010 - 45,182,180 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map21q22.3NCBI
HuRef2130,506,765 - 30,550,585 (+)NCBIHuRef
CHM1_12144,699,825 - 44,742,673 (+)NCBICHM1_1
T2T-CHM13v2.02142,074,671 - 42,117,910 (+)NCBIT2T-CHM13v2.0
PDXK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13137,686,002 - 37,710,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3137,685,492 - 37,707,767 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3136,836,971 - 36,865,273 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03137,225,468 - 37,251,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3137,225,486 - 37,253,813 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13137,093,275 - 37,121,572 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03137,079,116 - 37,107,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,571,216 - 37,599,584 (+)NCBIUU_Cfam_GSD_1.0
PDXK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13206,676,730 - 206,703,326 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113206,676,905 - 206,699,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

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Variants in PDXK
53 total Variants

1 to 10 of 186 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
NM_003681.5(PDXK):c.407A>G (p.Tyr136Cys) single nucleotide variant not specified [RCV004307915] Chr21:43749023 [GRCh38]
Chr21:45168904 [GRCh37]
Chr21:21q22.3
uncertain significance
NM_003681.5(PDXK):c.148G>A (p.Ala50Thr) single nucleotide variant not specified [RCV004296033] Chr21:43741672 [GRCh38]
Chr21:45161553 [GRCh37]
Chr21:21q22.3
uncertain significance
NM_003681.5(PDXK):c.760-8C>A single nucleotide variant PDXK-related disorder [RCV003980837]|not provided [RCV001643644] Chr21:43755690 [GRCh38]
Chr21:45175571 [GRCh37]
Chr21:21q22.3
benign
NM_003681.5(PDXK):c.631G>A (p.Ala211Thr) single nucleotide variant not provided [RCV001532460]|not specified [RCV004039230] Chr21:43753591 [GRCh38]
Chr21:45173472 [GRCh37]
Chr21:21q22.3
uncertain significance
NM_003681.5(PDXK):c.379-167T>C single nucleotide variant not provided [RCV001691226] Chr21:43748828 [GRCh38]
Chr21:45168709 [GRCh37]
Chr21:21q22.3
benign
NM_003681.5(PDXK):c.88-199A>G single nucleotide variant not provided [RCV001708058] Chr21:43733870 [GRCh38]
Chr21:45153751 [GRCh37]
Chr21:21q22.3
benign
NC_000021.9:g.43718989_43718996dup duplication not provided [RCV001648676] Chr21:43718988..43718989 [GRCh38]
Chr21:45138869..45138870 [GRCh37]
Chr21:21q22.3
benign
GRCh37/hg19 21q22.2-22.3(chr21:41254101-48097372)x1 copy number loss See cases [RCV000511808] Chr21:41254101..48097372 [GRCh37]
Chr21:21q22.2-22.3
pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:34789953-46636538)x1 copy number loss See cases [RCV000136828] Chr21:34789953..46636538 [GRCh38]
Chr21:36162250..48056450 [GRCh37]
Chr21:35084120..46880878 [NCBI36]
Chr21:21q22.12-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000140103] Chr21:7749532..46670346 [GRCh38]
Chr21:14577894..48090258 [GRCh37]
Chr21:13499765..46914686 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
1 to 10 of 186 rows

The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
406909094GWAS558070_Hbreast carcinoma QTL GWAS558070 (human)0.000002breast carcinoma214373382543733826Human
407006315GWAS655291_Hsystolic blood pressure change measurement QTL GWAS655291 (human)0.000001systolic blood pressure change measurementchange in systolic blood pressure (CMO:0000746)214376156543761566Human
2303081MAMTS49_HMammary tumor susceptibility QTL 49 (human)1.72Mammary tumor susceptibility211795044843950448Human
407006312GWAS655288_Hsystolic blood pressure change measurement QTL GWAS655288 (human)0.0000007systolic blood pressure change measurementchange in systolic blood pressure (CMO:0000746)214376156543761566Human






1 to 30 of 75 rows
RefSeq Transcripts NM_001331030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005261195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005261196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005261199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011529758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011529760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011529761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011529762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017028483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017028484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047441001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047441002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047441003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047441004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047441005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047441006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB621819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI131245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI652877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK024977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 75 rows

RefSeq Acc Id: NM_001331030   ⟹   NP_001317959
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,741,486 - 43,762,299 (+)NCBI
T2T-CHM13v2.02142,097,093 - 42,117,910 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003681   ⟹   NP_003672
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,719,129 - 43,762,299 (+)NCBI
T2T-CHM13v2.02142,074,671 - 42,117,910 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005261195   ⟹   XP_005261252
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,719,457 - 43,762,299 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005261196   ⟹   XP_005261253
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,733,578 - 43,762,299 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005261199   ⟹   XP_005261256
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,728,993 - 43,762,299 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011529761   ⟹   XP_011528063
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,741,486 - 43,762,299 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011529762   ⟹   XP_011528064
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,719,457 - 43,739,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047441001   ⟹   XP_047296957
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,730,928 - 43,762,299 (+)NCBI
RefSeq Acc Id: XM_047441002   ⟹   XP_047296958
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,734,069 - 43,762,299 (+)NCBI
RefSeq Acc Id: XM_047441003   ⟹   XP_047296959
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,741,666 - 43,762,299 (+)NCBI
RefSeq Acc Id: XM_047441004   ⟹   XP_047296960
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,728,900 - 43,762,299 (+)NCBI
RefSeq Acc Id: XM_047441005   ⟹   XP_047296961
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,719,129 - 43,762,299 (+)NCBI
RefSeq Acc Id: XM_047441006   ⟹   XP_047296962
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,733,323 - 43,762,299 (+)NCBI
RefSeq Acc Id: XM_054324884   ⟹   XP_054180859
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,075,052 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324885   ⟹   XP_054180860
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,086,469 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324886   ⟹   XP_054180861
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,089,121 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324887   ⟹   XP_054180862
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,089,612 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324888   ⟹   XP_054180863
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,097,273 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324889   ⟹   XP_054180864
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,074,671 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324890   ⟹   XP_054180865
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,074,930 - 42,094,404 (+)NCBI
RefSeq Acc Id: XM_054324891   ⟹   XP_054180866
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,084,534 - 42,117,910 (+)NCBI
RefSeq Acc Id: XM_054324892   ⟹   XP_054180867
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02142,088,866 - 42,117,910 (+)NCBI
1 to 30 of 48 rows
Protein RefSeqs NP_001317959 (Get FASTA)   NCBI Sequence Viewer  
  NP_003672 (Get FASTA)   NCBI Sequence Viewer  
  XP_005261252 (Get FASTA)   NCBI Sequence Viewer  
  XP_005261253 (Get FASTA)   NCBI Sequence Viewer  
  XP_005261256 (Get FASTA)   NCBI Sequence Viewer  
  XP_011528063 (Get FASTA)   NCBI Sequence Viewer  
  XP_011528064 (Get FASTA)   NCBI Sequence Viewer  
  XP_047296957 (Get FASTA)   NCBI Sequence Viewer  
  XP_047296958 (Get FASTA)   NCBI Sequence Viewer  
  XP_047296959 (Get FASTA)   NCBI Sequence Viewer  
  XP_047296960 (Get FASTA)   NCBI Sequence Viewer  
  XP_047296961 (Get FASTA)   NCBI Sequence Viewer  
  XP_047296962 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180859 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180860 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180861 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180862 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180863 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180864 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180865 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180866 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180867 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC51233 (Get FASTA)   NCBI Sequence Viewer  
  AAH00123 (Get FASTA)   NCBI Sequence Viewer  
  AAH05825 (Get FASTA)   NCBI Sequence Viewer  
  AAH08008 (Get FASTA)   NCBI Sequence Viewer  
  AAH21550 (Get FASTA)   NCBI Sequence Viewer  
  AAH41020 (Get FASTA)   NCBI Sequence Viewer  
  AAP73047 (Get FASTA)   NCBI Sequence Viewer  
  ACJ13696 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 48 rows
1 to 5 of 22 rows
1 to 5 of 22 rows
RefSeq Acc Id: NP_003672   ⟸   NM_003681
- Peptide Label: isoform 1
- UniProtKB: Q7Z2Y0 (UniProtKB/Swiss-Prot),   Q9BS02 (UniProtKB/Swiss-Prot),   O00764 (UniProtKB/Swiss-Prot),   V9HWC3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011528064   ⟸   XM_011529762
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_005261252   ⟸   XM_005261195
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005261256   ⟸   XM_005261199
- Peptide Label: isoform X5
- UniProtKB: O00764 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005261253   ⟸   XM_005261196
- Peptide Label: isoform X3
- Sequence:
Name Modeler Protein Id AA Range Protein Structure
AF-O00764-F1-model_v2 AlphaFold O00764 1-312 view protein structure

RGD ID:13602980
Promoter ID:EPDNEW_H27674
Type:initiation region
Name:PDXK_1
Description:pyridoxal kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H27675  EPDNEW_H27676  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,719,132 - 43,719,192EPDNEW
RGD ID:13602982
Promoter ID:EPDNEW_H27675
Type:initiation region
Name:PDXK_2
Description:pyridoxal kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H27674  EPDNEW_H27676  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,734,093 - 43,734,153EPDNEW
RGD ID:13602984
Promoter ID:EPDNEW_H27676
Type:initiation region
Name:PDXK_3
Description:pyridoxal kinase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H27674  EPDNEW_H27675  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,741,513 - 43,741,573EPDNEW


1 to 36 of 36 rows
Database
Acc Id
Source(s)
COSMIC PDXK COSMIC
Ensembl Genes ENSG00000160209 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000291565 ENTREZGENE
  ENST00000291565.9 UniProtKB/Swiss-Prot
  ENST00000327574.4 UniProtKB/TrEMBL
  ENST00000398081.5 UniProtKB/TrEMBL
  ENST00000467908 ENTREZGENE
  ENST00000467908.1 UniProtKB/TrEMBL
  ENST00000468090.5 UniProtKB/Swiss-Prot
  ENST00000621478.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1190.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000160209 GTEx
HGNC ID HGNC:8819 ENTREZGENE
Human Proteome Map PDXK Human Proteome Map
InterPro PM/HMP-P_kinase-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlKinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribokinase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8566 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene PDXK ENTREZGENE
OMIM 179020 OMIM
PANTHER PTHR10534 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PYRIDOXAL KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Phos_pyr_kin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA33162 PharmGKB
Superfamily-SCOP SSF53613 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0B4J2C9_HUMAN UniProtKB/TrEMBL
  A8MT14_HUMAN UniProtKB/TrEMBL
  A8MV33_HUMAN UniProtKB/TrEMBL
  F2Z2Y4 ENTREZGENE, UniProtKB/TrEMBL
  G1UI32_HUMAN UniProtKB/TrEMBL
  O00764 ENTREZGENE, UniProtKB/Swiss-Prot
  Q7Z2Y0 ENTREZGENE
  Q9BS02 ENTREZGENE
  V9HWC3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q7Z2Y0 UniProtKB/Swiss-Prot
  Q9BS02 UniProtKB/Swiss-Prot
1 to 36 of 36 rows