Pdxk (pyridoxal kinase) - Rat Genome Database

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Gene: Pdxk (pyridoxal kinase) Chinchilla lanigera
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Symbol: Pdxk
Name: pyridoxal kinase
RGD ID: 8918779
Description: ENCODES a protein that exhibits phosphotransferase activity, alcohol group as acceptor (ortholog); pyridoxal binding (ortholog); pyridoxal kinase activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); pyridoxal metabolic process (ortholog); pyridoxal phosphate biosynthetic process (ortholog); PARTICIPATES IN hypophosphatasia pathway; vitamin B6 metabolic pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pyridoxal (pyridoxine, vitamin B6) kinase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,482,216 - 41,494,177 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540741,482,216 - 41,494,174 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pdxk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,482,216 - 41,494,177 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540741,482,216 - 41,494,174 (-)NCBIChiLan1.0ChiLan1.0
PDXK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,737,000 - 43,738,097 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,719,094 - 43,762,307 (+)EnsemblGRCh38hg38GRCh38
GRCh372145,138,978 - 45,182,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,963,406 - 44,006,616 (+)NCBINCBI36Build 36hg18NCBI36
Build 342143,963,405 - 44,006,608NCBI
Celera2130,244,819 - 30,287,780 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2130,506,765 - 30,550,585 (+)NCBIHuRef
CHM1_12144,717,696 - 44,718,791 (+)NCBICHM1_1
T2T-CHM13v2.02142,092,543 - 42,093,640 (+)NCBIT2T-CHM13v2.0
Pdxk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,272,581 - 78,300,782 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,272,578 - 78,300,809 (-)EnsemblGRCm39 Ensembl
GRCm381078,436,747 - 78,464,948 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,436,744 - 78,464,975 (-)EnsemblGRCm38mm10GRCm38
MGSCv371077,899,492 - 77,927,693 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361077,842,099 - 77,868,104 (-)NCBIMGSCv36mm8
Celera1079,458,844 - 79,487,046 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Pdxk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82010,209,975 - 10,232,012 (+)NCBIGRCr8
mRatBN7.22010,210,276 - 10,232,314 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2010,210,289 - 10,232,110 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2010,909,956 - 10,931,608 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02010,270,865 - 10,292,517 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02010,742,295 - 10,763,997 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02010,930,651 - 10,952,194 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,930,518 - 10,952,391 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,102,429 - 13,123,972 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,541,656 - 10,563,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12010,541,882 - 10,563,426 (+)NCBI
Celera2011,721,159 - 11,742,702 (+)NCBICelera
Cytogenetic Map20p12NCBI
PDXK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22239,727,200 - 39,771,206 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12134,577,814 - 34,621,766 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02129,977,286 - 30,021,266 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12143,276,660 - 43,319,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2143,273,237 - 43,313,637 (+)Ensemblpanpan1.1panPan2
Pdxk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497136,928,712 - 36,956,834 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936500509,510 - 529,455 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936500510,977 - 539,166 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDXK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1287,489,249 - 87,534,376 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl287,489,315 - 87,531,621 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605415,561,891 - 15,606,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdxk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474530,157,446 - 30,175,803 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474530,157,446 - 30,175,905 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000007196   ⟹   ENSCLAP00000007084
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540741,482,216 - 41,494,177 (-)Ensembl
RefSeq Acc Id: XM_013505430   ⟹   XP_013360884
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540741,482,216 - 41,494,174 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013360884 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007084
  ENSCLAP00000007084.1
RefSeq Acc Id: XP_013360884   ⟸   XM_013505430
- UniProtKB: A0A8C2V0S0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000007084   ⟸   ENSCLAT00000007196

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004982 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007196 ENTREZGENE
  ENSCLAT00000007196.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1190.20 UniProtKB/TrEMBL
InterPro PM/HMP-P_kinase-1 UniProtKB/TrEMBL
  PyrdxlKinase UniProtKB/TrEMBL
  Ribokinase-like UniProtKB/TrEMBL
NCBI Gene Pdxk ENTREZGENE
PANTHER PTHR10534 UniProtKB/TrEMBL
  PYRIDOXAL KINASE UniProtKB/TrEMBL
Pfam Phos_pyr_kin UniProtKB/TrEMBL
Superfamily-SCOP SSF53613 UniProtKB/TrEMBL
UniProt A0A8C2V0S0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-17 Pdxk  pyridoxal kinase    pyridoxal (pyridoxine, vitamin B6) kinase  Symbol and/or name change 5135510 APPROVED