PDXK (pyridoxal kinase) - Rat Genome Database

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Gene: PDXK (pyridoxal kinase) Canis lupus familiaris
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Symbol: PDXK
Name: pyridoxal kinase
RGD ID: 12192240
Description: ENCODES a protein that exhibits ATP binding (ortholog); lithium ion binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN pyridoxal 5'-phosphate salvage (inferred); vitamin B6 metabolic process (inferred); ASSOCIATED WITH autistic disorder (ortholog); cataract 9 multiple types (ortholog); Charcot-Marie-Tooth Disease Type 6C (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pyridoxal (pyridoxine, vitamin B6) kinase
RGD Orthologs
Human
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13137,686,002 - 37,710,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3137,685,492 - 37,707,767 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3136,836,971 - 36,865,273 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03137,225,468 - 37,251,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3137,225,486 - 37,253,813 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13137,093,275 - 37,121,572 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03137,079,116 - 37,107,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,571,216 - 37,599,584 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PDXK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13137,686,002 - 37,710,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3137,685,492 - 37,707,767 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3136,836,971 - 36,865,273 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03137,225,468 - 37,251,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3137,225,486 - 37,253,813 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13137,093,275 - 37,121,572 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03137,079,116 - 37,107,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,571,216 - 37,599,584 (+)NCBIUU_Cfam_GSD_1.0
PDXK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,719,129 - 43,762,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,719,094 - 43,762,307 (+)EnsemblGRCh38hg38GRCh38
GRCh372145,139,010 - 45,182,180 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map21q22.3NCBI
HuRef2130,506,765 - 30,550,585 (+)NCBIHuRef
CHM1_12144,699,825 - 44,742,673 (+)NCBICHM1_1
T2T-CHM13v2.02142,074,671 - 42,117,910 (+)NCBIT2T-CHM13v2.0
PDXK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13206,676,730 - 206,703,326 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113206,676,905 - 206,699,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in PDXK
817 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005638956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014109778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038443615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038443616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038443617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038461771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038518027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038581601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000049673   ⟹   ENSCAFP00000040867
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3137,698,743 - 37,707,767 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000081682   ⟹   ENSCAFP00000064875
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3137,688,984 - 37,707,767 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000084026   ⟹   ENSCAFP00000044317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3137,685,492 - 37,707,767 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845032379   ⟹   ENSCAFP00845025310
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3137,225,486 - 37,253,813 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845032494   ⟹   ENSCAFP00845025409
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3137,225,486 - 37,253,813 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845032602   ⟹   ENSCAFP00845025500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3137,225,534 - 37,252,344 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845032673   ⟹   ENSCAFP00845025557
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3137,232,797 - 37,251,442 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845032751   ⟹   ENSCAFP00845025624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3137,242,510 - 37,253,813 (+)Ensembl
RefSeq Acc Id: XM_005638956   ⟹   XP_005639013
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13137,689,099 - 37,710,059 (+)NCBI
Dog10K_Boxer_Tasha3136,844,360 - 36,865,273 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014109778   ⟹   XP_013965253
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13137,686,002 - 37,710,059 (+)NCBI
Dog10K_Boxer_Tasha3136,841,493 - 36,865,273 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038443615   ⟹   XP_038299543
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03137,229,991 - 37,251,568 (+)NCBI
RefSeq Acc Id: XM_038443616   ⟹   XP_038299544
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03137,232,851 - 37,251,568 (+)NCBI
RefSeq Acc Id: XM_038443617   ⟹   XP_038299545
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03137,225,468 - 37,251,568 (+)NCBI
RefSeq Acc Id: XM_038461771   ⟹   XP_038317699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3136,836,971 - 36,865,273 (+)NCBI
RefSeq Acc Id: XM_038518025   ⟹   XP_038373953
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13137,097,790 - 37,121,572 (+)NCBI
RefSeq Acc Id: XM_038518026   ⟹   XP_038373954
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13137,100,644 - 37,121,572 (+)NCBI
RefSeq Acc Id: XM_038518027   ⟹   XP_038373955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13137,093,275 - 37,121,572 (+)NCBI
RefSeq Acc Id: XM_038581601   ⟹   XP_038437529
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03137,571,216 - 37,599,584 (+)NCBI
RefSeq Acc Id: XM_038645991   ⟹   XP_038501919
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03137,083,631 - 37,107,424 (+)NCBI
RefSeq Acc Id: XM_038645992   ⟹   XP_038501920
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03137,086,482 - 37,107,424 (+)NCBI
RefSeq Acc Id: XM_038645993   ⟹   XP_038501921
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03137,079,116 - 37,107,424 (+)NCBI
RefSeq Acc Id: XP_013965253   ⟸   XM_014109778
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L5R9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005639013   ⟸   XM_005638956
- Peptide Label: isoform X2
- UniProtKB: A0A8P0PDH8 (UniProtKB/TrEMBL),   A0A8C0SI18 (UniProtKB/TrEMBL),   A0A8P0SUQ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000040867   ⟸   ENSCAFT00000049673
Ensembl Acc Id: ENSCAFP00000044317   ⟸   ENSCAFT00000084026
Ensembl Acc Id: ENSCAFP00000064875   ⟸   ENSCAFT00000081682
RefSeq Acc Id: XP_038373955   ⟸   XM_038518027
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038373953   ⟸   XM_038518025
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038373954   ⟸   XM_038518026
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038501921   ⟸   XM_038645993
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038501919   ⟸   XM_038645991
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038501920   ⟸   XM_038645992
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038299545   ⟸   XM_038443617
- Peptide Label: isoform X3
- UniProtKB: A0A8I3NV46 (UniProtKB/TrEMBL),   A0A8I3P3Y0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299543   ⟸   XM_038443615
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L5R9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299544   ⟸   XM_038443616
- Peptide Label: isoform X2
- UniProtKB: A0A8I3NWJ0 (UniProtKB/TrEMBL),   A0A8I3NVW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038317699   ⟸   XM_038461771
- Peptide Label: isoform X3
- UniProtKB: A0A8C0SJ14 (UniProtKB/TrEMBL),   A0A8P0PII2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038437529   ⟸   XM_038581601
- Peptide Label: isoform X3
- UniProtKB: A0A8C0SJ14 (UniProtKB/TrEMBL),   A0A8P0PII2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845025624   ⟸   ENSCAFT00845032751
Ensembl Acc Id: ENSCAFP00845025557   ⟸   ENSCAFT00845032673
Ensembl Acc Id: ENSCAFP00845025310   ⟸   ENSCAFT00845032379
Ensembl Acc Id: ENSCAFP00845025409   ⟸   ENSCAFT00845032494
Ensembl Acc Id: ENSCAFP00845025500   ⟸   ENSCAFT00845032602

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031322 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040013368 UniProtKB/TrEMBL
  ENSCAFG00845018299 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049673.3 UniProtKB/TrEMBL
  ENSCAFT00000081682.2 UniProtKB/TrEMBL
  ENSCAFT00000084026.2 UniProtKB/TrEMBL
  ENSCAFT00000094807.1 UniProtKB/TrEMBL
  ENSCAFT00000096495.1 UniProtKB/TrEMBL
  ENSCAFT00000097572.1 UniProtKB/TrEMBL
  ENSCAFT00000100594.1 UniProtKB/TrEMBL
  ENSCAFT00000104986.1 UniProtKB/TrEMBL
  ENSCAFT00040024912.1 UniProtKB/TrEMBL
  ENSCAFT00040024995.1 UniProtKB/TrEMBL
  ENSCAFT00040025076.1 UniProtKB/TrEMBL
  ENSCAFT00040025139.1 UniProtKB/TrEMBL
  ENSCAFT00845032379 ENTREZGENE
  ENSCAFT00845032379.1 UniProtKB/TrEMBL
  ENSCAFT00845032494.1 UniProtKB/TrEMBL
  ENSCAFT00845032602.1 UniProtKB/TrEMBL
  ENSCAFT00845032673 ENTREZGENE
  ENSCAFT00845032673.1 UniProtKB/TrEMBL
  ENSCAFT00845032751.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1190.20 UniProtKB/TrEMBL
InterPro PM/HMP-P_kinase-1 UniProtKB/TrEMBL
  PyrdxlKinase UniProtKB/TrEMBL
  Ribokinase-like UniProtKB/TrEMBL
KEGG Report cfa:487788 UniProtKB/TrEMBL
NCBI Gene PDXK ENTREZGENE
PANTHER PTHR10534 UniProtKB/TrEMBL
  PYRIDOXAL KINASE UniProtKB/TrEMBL
Pfam Phos_pyr_kin UniProtKB/TrEMBL
Superfamily-SCOP SSF53613 UniProtKB/TrEMBL
UniProt A0A8C0L5R9 ENTREZGENE
  A0A8C0SI18 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SIM8_CANLF UniProtKB/TrEMBL
  A0A8C0SIU8_CANLF UniProtKB/TrEMBL
  A0A8C0SJ14 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NV46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NVW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NWJ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P2I9_CANLF UniProtKB/TrEMBL
  A0A8I3P3Y0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PDH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PII2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SUQ8 ENTREZGENE
  A0A8P0SXK0_CANLF UniProtKB/TrEMBL
  A0A8P0TIT1_CANLF UniProtKB/TrEMBL
  A0A8P0TLC1_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0PFN3 UniProtKB/TrEMBL
  A0A8P0PRA5 UniProtKB/TrEMBL
  A0A8P0SUQ8 UniProtKB/TrEMBL
VGNC ID VGNC:49939 ENTREZGENE