Arhgap33 (Rho GTPase activating protein 33) - Rat Genome Database

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Gene: Arhgap33 (Rho GTPase activating protein 33) Rattus norvegicus
Analyze
Symbol: Arhgap33
Name: Rho GTPase activating protein 33
RGD ID: 2318374
Description: Predicted to enable GTPase activator activity and protein kinase binding activity. Involved in regulation of dendritic spine morphogenesis and response to toxic substance. Located in dendritic spine. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human ARHGAP33 (Rho GTPase activating protein 33); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100362311; LOC361540; rho GTPase-activating protein 33; Snx26; sorting nexin 26
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   WAG.OXYS-(D1Rat30-D1Rat219)/Nov  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,903,566 - 94,917,074 (-)NCBIGRCr8
mRatBN7.2185,776,112 - 85,789,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0188,977,460 - 88,990,780 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,978,344 - 88,989,552 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,132,465 - 90,145,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,568,846 - 85,581,069 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera180,147,918 - 80,160,861 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap33Ratautism spectrum disorder  ISOArhgap33 (Mus musculus)126848764 RGD 
Arhgap33Ratdisease of mental health  ISOArhgap33 (Mus musculus)11343316 RGD 
Arhgap33Rattemporal lobe epilepsy  ISOArhgap33 (Mus musculus)126848765protein:increased phosphorylation:hippocampusRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap33RatBrugada syndrome 5  ISOARHGAP33 (Homo sapiens)8554872ClinVar Annotator: match by term: Brugada syndrome 5ClinVarPMID:28492532
Arhgap33Rathereditary spastic paraplegia 75  ISOARHGAP33 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 75ClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap33Rat1,2-dimethylhydrazine increases expressionISOArhgap33 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of ARHGAP33 mRNACTDPMID:22206623
Arhgap33Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of ARHGAP33 mRNACTDPMID:35192832
Arhgap33Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOArhgap33 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARHGAP33 promoter]CTDPMID:19654925
Arhgap33Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of ARHGAP33 mRNACTDPMID:33387578
Arhgap33Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of ARHGAP33 mRNACTDPMID:21346803
Arhgap33Rat3,4-methylenedioxymethamphetamine increases expressionISOArhgap33 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ARHGAP33 mRNACTDPMID:26251327
Arhgap33Ratarsane affects methylationISOARHGAP33 (Homo sapiens)6480464Arsenic affects the methylation of ARHGAP33 geneCTDPMID:25304211
Arhgap33Ratarsenic atom affects methylationISOARHGAP33 (Homo sapiens)6480464Arsenic affects the methylation of ARHGAP33 geneCTDPMID:25304211
Arhgap33Ratbenzo[a]pyrene decreases methylationISOARHGAP33 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of ARHGAP33 3' UTRCTDPMID:27901495
Arhgap33Ratbeta-lapachone decreases expressionISOARHGAP33 (Homo sapiens)6480464beta-lapachone results in decreased expression of ARHGAP33 mRNACTDPMID:38218311
Arhgap33Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of ARHGAP33 mRNACTDPMID:25181051 more ...
Arhgap33Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of ARHGAP33 mRNACTDPMID:38750585
Arhgap33Ratbisphenol A decreases expressionISOArhgap33 (Mus musculus)6480464bisphenol A results in decreased expression of ARHGAP33 mRNACTDPMID:32156529 and PMID:38074096
Arhgap33RatC60 fullerene decreases expressionEXP 6480464fullerene C60 results in decreased expression of ARHGAP33 mRNACTDPMID:19167457
Arhgap33Ratcadmium atom multiple interactionsISOARHGAP33 (Homo sapiens)6480464[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ARHGAP33 mRNACTDPMID:35301059
Arhgap33Ratcadmium dichloride multiple interactionsISOARHGAP33 (Homo sapiens)6480464[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ARHGAP33 mRNACTDPMID:35301059
Arhgap33Ratcarbon nanotube multiple interactionsISOARHGAP33 (Homo sapiens)6480464[Nanotubes and Carbon co-treated with calfactant] results in increased expression of ARHGAP33 proteinCTDPMID:23026733
Arhgap33Ratchlorpyrifos increases expressionISOArhgap33 (Mus musculus)6480464Chlorpyrifos results in increased expression of ARHGAP33 mRNACTDPMID:37019170
Arhgap33Ratcisplatin decreases expressionISOARHGAP33 (Homo sapiens)6480464Cisplatin results in decreased expression of ARHGAP33 mRNACTDPMID:27392435
Arhgap33Ratcisplatin multiple interactionsISOARHGAP33 (Homo sapiens)6480464[Cisplatin co-treated with jinfukang] results in decreased expression of ARHGAP33 mRNACTDPMID:27392435

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Biological Process

  

Cellular Component
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap33Ratactin cytoskeleton is_active_inIBAMGI:2450166 and PANTHER:PTN0026965761600115GO_REF:0000033GO_CentralGO_REF:0000033
Arhgap33Ratcell cortex is_active_inIBAMGI:2450166 and PANTHER:PTN0026965761600115GO_REF:0000033GO_CentralGO_REF:0000033
Arhgap33Ratcytoplasm located_inIEAUniProtKB:Q80YF9 and ensembl:ENSMUSP000001466021600115GO_REF:0000107EnsemblGO_REF:0000107
Arhgap33Ratcytoplasm located_inISOArhgap33 (Mus musculus)1624291 PMID:12773384RGDPMID:12773384
Arhgap33Ratdendritic spine  IDA 13508596 RGD 
Arhgap33Ratfibrillar center is_active_inIBAPANTHER:PTN002696576 and UniProtKB:A7KAX91600115GO_REF:0000033GO_CentralGO_REF:0000033
Arhgap33Ratglutamatergic synapse is_active_inIMP 13508596PMID:24003235SynGO 
Arhgap33Ratglutamatergic synapse is_active_inISOArhgap33 (Mus musculus)1624291 PMID:24003235RGDPMID:24003235
Arhgap33Ratglutamatergic synapse is_active_inIEAUniProtKB:Q80YF9 and ensembl:ENSMUSP000001466021600115GO_REF:0000107EnsemblGO_REF:0000107
Arhgap33Ratglutamatergic synapse is_active_inIDA 13508596PMID:24003235SynGO 
Arhgap33RatGolgi apparatus is_active_inIBAPANTHER:PTN002696576 and UniProtKB:A7KAX91600115GO_REF:0000033GO_CentralGO_REF:0000033
Arhgap33Ratnucleoplasm is_active_inIBAPANTHER:PTN002696576 and UniProtKB:A7KAX91600115GO_REF:0000033GO_CentralGO_REF:0000033
Arhgap33Ratplasma membrane located_inIEAUniProtKB:Q80YF9 and ensembl:ENSMUSP000001466021600115GO_REF:0000107EnsemblGO_REF:0000107
Arhgap33Ratplasma membrane located_inISOArhgap33 (Mus musculus)1624291 PMID:12773384RGDPMID:12773384
Arhgap33Ratplasma membrane is_active_inIBAMGI:2673998 and PANTHER:PTN0085614121600115GO_REF:0000033GO_CentralGO_REF:0000033
Arhgap33Ratpostsynaptic density is_active_inIMP 13508596PMID:24003235SynGO 
Arhgap33Ratpostsynaptic density is_active_inIDA 13508596PMID:24003235SynGO 
Arhgap33Ratprotein-containing complex part_ofISOARHGAP33 (Homo sapiens)1624291 PMID:20873783RGDPMID:20873783
Arhgap33Ratprotein-containing complex part_ofIEAUniProtKB:O14559 and ensembl:ENSP000000075101600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. SNX26, a GTPase-activating protein for Cdc42, interacts with PSD-95 protein and is involved in activity-dependent dendritic spine formation in mature neurons. Kim Y, etal., J Biol Chem. 2013 Oct 11;288(41):29453-66. doi: 10.1074/jbc.M113.468801. Epub 2013 Sep 3.
3. Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders. Nakazawa T, etal., Nat Commun. 2016 Feb 3;7:10594. doi: 10.1038/ncomms10594.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. NOMA-GAP/ARHGAP33 regulates synapse development and autistic-like behavior in the mouse. Schuster S, etal., Mol Psychiatry. 2015 Sep;20(9):1120-31. doi: 10.1038/mp.2015.42. Epub 2015 Apr 14.
7. [Chronic phosphoproteomic in temporal lobe epilepsy mouse models induced by kainic acid]. Sun ZM, etal., Beijing Da Xue Xue Bao Yi Xue Ban. 2019 Apr 18;51(2):197-205.
PMID:12773384   PMID:20873783  



Arhgap33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,903,566 - 94,917,074 (-)NCBIGRCr8
mRatBN7.2185,776,112 - 85,789,767 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0188,977,460 - 88,990,780 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,978,344 - 88,989,552 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,132,465 - 90,145,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,568,846 - 85,581,069 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera180,147,918 - 80,160,861 (-)NCBICelera
Cytogenetic Map1q21NCBI
ARHGAP33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,775,564 - 35,788,822 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,774,532 - 35,788,822 (+)EnsemblGRCh38hg38GRCh38
GRCh371936,266,466 - 36,279,724 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,958,316 - 40,971,564 (+)NCBINCBI36Build 36hg18NCBI36
Build 341940,958,315 - 40,971,564NCBI
Celera1932,979,892 - 32,993,199 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,771,250 - 32,784,558 (+)NCBIHuRef
CHM1_11936,267,718 - 36,281,025 (+)NCBICHM1_1
T2T-CHM13v2.01938,320,866 - 38,334,124 (+)NCBIT2T-CHM13v2.0
Arhgap33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,221,651 - 30,234,596 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,221,651 - 30,234,485 (-)EnsemblGRCm39 Ensembl
GRCm38730,522,225 - 30,535,171 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,522,226 - 30,535,060 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,307,245 - 31,320,028 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,230,986 - 30,243,769 (-)NCBIMGSCv36mm8
Celera725,113,538 - 25,126,798 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map718.43NCBI
Arhgap33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554682,769,493 - 2,783,155 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554682,769,108 - 2,783,746 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,769,327 - 41,783,117 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,754,625 - 43,768,439 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,704,877 - 32,710,778 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,438,870 - 41,452,173 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,439,010 - 41,452,173 (+)Ensemblpanpan1.1panPan2
ARHGAP33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,851,341 - 116,864,696 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,851,328 - 116,864,561 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,256,654 - 116,269,983 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,454,351 - 117,467,681 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,454,358 - 117,467,680 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,017,748 - 117,031,089 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,641,363 - 116,654,689 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,696,728 - 117,710,063 (-)NCBIUU_Cfam_GSD_1.0
Arhgap33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,092,833 - 11,106,043 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570539,830 - 553,086 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936570539,839 - 553,018 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,199,456 - 45,213,653 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,198,657 - 45,213,655 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,643,417 - 40,645,900 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,684,679 - 30,697,943 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,684,731 - 30,697,556 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660738,476,038 - 8,489,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479410,075,462 - 10,088,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479410,075,329 - 10,089,356 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Arhgap33
17 total Variants

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:9
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000034001
Prediction methods:Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 39 rows
AW324378  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2185,776,417 - 85,776,507 (+)MAPPERmRatBN7.2
Rnor_6.0188,977,757 - 88,977,846NCBIRnor6.0
Rnor_5.0190,132,762 - 90,132,851UniSTSRnor5.0
RGSC_v3.4185,568,786 - 85,568,875UniSTSRGSC3.4
Celera180,148,215 - 80,148,304UniSTS
Cytogenetic Map1q21UniSTS
RH132495  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2838,049,478 - 38,049,668 (+)MAPPERmRatBN7.2
mRatBN7.2185,776,181 - 85,776,366 (+)MAPPERmRatBN7.2
Rnor_6.0188,977,521 - 88,977,705NCBIRnor6.0
Rnor_6.0840,745,691 - 40,745,880NCBIRnor6.0
Rnor_5.0840,740,124 - 40,740,313UniSTSRnor5.0
Rnor_5.0190,132,526 - 90,132,710UniSTSRnor5.0
RGSC_v3.4185,568,550 - 85,568,734UniSTSRGSC3.4
RGSC_v3.4839,651,899 - 39,652,088UniSTSRGSC3.4
Celera836,416,128 - 36,416,317UniSTS
Celera180,147,979 - 80,148,163UniSTS
RH 3.4 Map81141.5UniSTS
Cytogenetic Map1q21UniSTS
UniSTS:235645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2838,048,541 - 38,048,781 (+)MAPPERmRatBN7.2
mRatBN7.2185,777,056 - 85,777,276 (+)MAPPERmRatBN7.2
Rnor_6.0188,978,908 - 88,979,127NCBIRnor6.0
Rnor_6.0840,744,754 - 40,744,993NCBIRnor6.0
Rnor_5.0840,739,187 - 40,739,426UniSTSRnor5.0
Rnor_5.0190,133,913 - 90,134,132UniSTSRnor5.0
RGSC_v3.4185,569,460 - 85,569,679UniSTSRGSC3.4
RGSC_v3.4839,650,962 - 39,651,201UniSTSRGSC3.4
Celera836,417,015 - 36,417,254UniSTS
Celera180,148,863 - 80,149,082UniSTS
Cytogenetic Map1q21UniSTS
MARC_4163-4164:996679454:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2185,782,059 - 85,782,488 (+)MAPPERmRatBN7.2
Rnor_6.0188,983,910 - 88,984,338NCBIRnor6.0
Rnor_5.0190,138,915 - 90,139,343UniSTSRnor5.0
RGSC_v3.4185,574,462 - 85,574,890UniSTSRGSC3.4
Celera180,153,865 - 80,154,293UniSTS
Cytogenetic Map1q21UniSTS


The following Strains have been annotated to Arhgap33
WAG.OXYS-(D1Rat30-D1Rat219)/Nov    




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 18 of 18 rows
RefSeq Transcripts NM_001432740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001432742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003753235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 18 of 18 rows

Ensembl Acc Id: ENSRNOT00000034001   ⟹   ENSRNOP00000033946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)Ensembl
Rnor_6.0 Ensembl188,978,344 - 88,989,552 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098974   ⟹   ENSRNOP00000095489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl185,776,108 - 85,789,678 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112416   ⟹   ENSRNOP00000087660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl185,778,283 - 85,789,678 (-)Ensembl
RefSeq Acc Id: XM_039093893   ⟹   XP_038949821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,995 (-)NCBI
mRatBN7.2185,776,112 - 85,789,706 (-)NCBI
RefSeq Acc Id: XM_039093902   ⟹   XP_038949830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,917,000 (-)NCBI
mRatBN7.2185,776,112 - 85,789,615 (-)NCBI
RefSeq Acc Id: XM_039093910   ⟹   XP_038949838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,997 (-)NCBI
mRatBN7.2185,776,112 - 85,789,615 (-)NCBI
RefSeq Acc Id: XM_039093911   ⟹   XP_038949839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,835 (-)NCBI
mRatBN7.2185,776,112 - 85,789,392 (-)NCBI
RefSeq Acc Id: XM_039093913   ⟹   XP_038949841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,908,110 - 94,917,074 (-)NCBI
mRatBN7.2185,780,666 - 85,789,713 (-)NCBI
RefSeq Acc Id: XM_063277857   ⟹   XP_063133927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,834 (-)NCBI
RefSeq Acc Id: XM_063277859   ⟹   XP_063133929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,916,021 (-)NCBI
RefSeq Acc Id: XM_063277862   ⟹   XP_063133932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,903,566 - 94,914,919 (-)NCBI
RefSeq Acc Id: XR_005494027
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,907,340 - 94,917,074 (-)NCBI
mRatBN7.2185,779,987 - 85,789,767 (-)NCBI
RefSeq Acc Id: XR_005494029
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8194,907,340 - 94,917,074 (-)NCBI
mRatBN7.2185,779,987 - 85,789,767 (-)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
Ensembl Acc Id: ENSRNOP00000033946   ⟸   ENSRNOT00000034001
RefSeq Acc Id: XP_038949821   ⟸   XM_039093893
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949838   ⟸   XM_039093910
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949830   ⟸   XM_039093902
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949839   ⟸   XM_039093911
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AJS5 (UniProtKB/TrEMBL),   D4A9G6 (UniProtKB/TrEMBL)
Rho-GAP   SH3

Name Modeler Protein Id AA Range Protein Structure
AF-D4A9G6-F1-model_v2 AlphaFold D4A9G6 1-1310 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-60105 BioCyc
Ensembl Genes ENSRNOG00000024677 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034001 ENTREZGENE
  ENSRNOT00000034001.5 UniProtKB/TrEMBL
  ENSRNOT00000098974 ENTREZGENE
  ENSRNOT00000098974.1 UniProtKB/TrEMBL
  ENSRNOT00000112416.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro PX-Rho_GAP UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene 100362311 ENTREZGENE
PANTHER CDC42 GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
  PTHR15729:SF11 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Arhgap33 PhenoGen
PROSITE RHOGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024677 RatGTEx
SMART RhoGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP 64268 UniProtKB/TrEMBL
  Rho_GAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
UniProt A0A8I6A7N0_RAT UniProtKB/TrEMBL
  A0A8I6AJS5 ENTREZGENE, UniProtKB/TrEMBL
  A6J9Y1 ENTREZGENE, UniProtKB/TrEMBL
  D4A9G6 ENTREZGENE, UniProtKB/TrEMBL
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-18 Arhgap33  Rho GTPase activating protein 33  Snx26  sorting nexin 26  Data merged from RGD:1308780 737654 APPROVED
2012-08-27 Arhgap33  Rho GTPase activating protein 33  LOC100362311  sorting nexin 26  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100362311  sorting nexin 26      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Snx26  sorting nexin 26   Snx26_predicted  sorting nexin 26 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Snx26_predicted  sorting nexin 26 (predicted)      Symbol and Name status set to approved 70820 APPROVED