Med12 (mediator complex subunit 12) - Rat Genome Database

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Gene: Med12 (mediator complex subunit 12) Heterocephalus glaber
Analyze
Symbol: Med12
Name: mediator complex subunit 12
RGD ID: 18933796
Description: ENCODES a protein that exhibits chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); embryonic neurocranium morphogenesis (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); angiosarcoma (ortholog); FOUND IN CKM complex (ortholog); ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mediator of RNA polymerase II transcription subunit 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249031,412,474 - 1,436,474 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249031,412,346 - 1,436,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Med12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249031,412,474 - 1,436,474 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249031,412,346 - 1,436,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MED12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,118,596 - 71,142,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX71,118,543 - 71,144,103 (+)EnsemblGRCh38hg38GRCh38
GRCh37X70,338,446 - 70,362,300 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,255,131 - 70,279,029 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X70,121,593 - 70,145,168NCBI
CeleraX70,692,310 - 70,716,179 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX64,157,722 - 64,181,176 (+)NCBIHuRef
CHM1_1X70,231,161 - 70,255,024 (+)NCBICHM1_1
T2T-CHM13v2.0X69,551,517 - 69,576,535 (+)NCBIT2T-CHM13v2.0
Med12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,317,697 - 100,342,540 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX100,317,636 - 100,341,071 (+)EnsemblGRCm39 Ensembl
GRCm38X101,274,091 - 101,298,934 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,274,030 - 101,297,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X98,469,430 - 98,494,273 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X97,477,613 - 97,499,990 (+)NCBIMGSCv36mm8
CeleraX88,190,265 - 88,214,981 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX43.91NCBI
Med12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X70,444,615 - 70,467,780 (+)NCBIGRCr8
mRatBN7.2X66,404,807 - 66,427,775 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX66,404,760 - 66,428,387 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX67,888,182 - 67,911,125 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X71,388,570 - 71,411,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X68,949,477 - 68,972,420 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X71,174,653 - 71,197,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,174,699 - 71,197,812 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X72,027,135 - 72,050,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,351,546 - 89,374,489 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX66,760,730 - 66,783,673 (+)NCBICelera
Cytogenetic MapXq22NCBI
Med12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547510,687,367 - 10,710,053 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547510,687,168 - 10,710,286 (+)NCBIChiLan1.0ChiLan1.0
MED12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X70,795,965 - 70,819,857 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X70,799,572 - 70,823,460 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X70,443,467 - 70,467,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,443,667 - 70,466,942 (+)Ensemblpanpan1.1panPan2
MED12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,487,629 - 55,508,941 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,482,013 - 55,509,992 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX46,314,714 - 46,337,057 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X56,456,534 - 56,465,517 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X54,424,767 - 54,447,085 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X55,756,191 - 55,778,506 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X55,683,336 - 55,705,668 (+)NCBIUU_Cfam_GSD_1.0
Med12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,697,933 - 46,721,139 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936762460,342 - 483,195 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936762460,342 - 483,264 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX57,150,919 - 57,175,333 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X57,150,884 - 57,174,367 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X64,681,038 - 64,704,523 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MED12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,915,796 - 60,939,220 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX60,915,703 - 60,937,677 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660652,776,278 - 2,799,983 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004872632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004872633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021250540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01102126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000007535   ⟹   ENSHGLP00000007450
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249031,412,474 - 1,436,474 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000007536   ⟹   ENSHGLP00000007451
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249031,412,537 - 1,436,241 (+)Ensembl
RefSeq Acc Id: XM_004872632   ⟹   XP_004872689
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,352 - 1,436,391 (+)NCBI
RefSeq Acc Id: XM_004872633   ⟹   XP_004872690
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,351 - 1,436,391 (+)NCBI
RefSeq Acc Id: XM_021250526   ⟹   XP_021106185
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,349 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250527   ⟹   XP_021106186
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,348 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250528   ⟹   XP_021106187
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,348 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250529   ⟹   XP_021106188
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,350 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250530   ⟹   XP_021106189
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,350 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250531   ⟹   XP_021106190
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,347 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250532   ⟹   XP_021106191
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,346 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250533   ⟹   XP_021106192
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,346 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250535   ⟹   XP_021106194
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,515 - 1,436,474 (+)NCBI
RefSeq Acc Id: XM_021250536   ⟹   XP_021106195
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,350 - 1,436,391 (+)NCBI
RefSeq Acc Id: XM_021250537   ⟹   XP_021106196
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,350 - 1,436,391 (+)NCBI
RefSeq Acc Id: XM_021250538   ⟹   XP_021106197
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,349 - 1,436,391 (+)NCBI
RefSeq Acc Id: XM_021250539   ⟹   XP_021106198
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,351 - 1,436,391 (+)NCBI
RefSeq Acc Id: XM_021250540   ⟹   XP_021106199
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249031,412,350 - 1,436,391 (+)NCBI
RefSeq Acc Id: XP_021106191   ⟸   XM_021250532
- Peptide Label: isoform X7
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106192   ⟸   XM_021250533
- Peptide Label: isoform X8
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106190   ⟸   XM_021250531
- Peptide Label: isoform X6
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106186   ⟸   XM_021250527
- Peptide Label: isoform X2
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106187   ⟸   XM_021250528
- Peptide Label: isoform X3
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106185   ⟸   XM_021250526
- Peptide Label: isoform X1
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106197   ⟸   XM_021250538
- Peptide Label: isoform X14
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106188   ⟸   XM_021250529
- Peptide Label: isoform X4
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106189   ⟸   XM_021250530
- Peptide Label: isoform X5
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106195   ⟸   XM_021250536
- Peptide Label: isoform X10
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106196   ⟸   XM_021250537
- Peptide Label: isoform X11
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106199   ⟸   XM_021250540
- Peptide Label: isoform X16
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106198   ⟸   XM_021250539
- Peptide Label: isoform X15
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872690   ⟸   XM_004872633
- Peptide Label: isoform X13
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872689   ⟸   XM_004872632
- Peptide Label: isoform X12
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106194   ⟸   XM_021250535
- Peptide Label: isoform X9
- UniProtKB: G5BW30 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000007451   ⟸   ENSHGLT00000007536
Ensembl Acc Id: ENSHGLP00000007450   ⟸   ENSHGLT00000007535


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005421 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007535 ENTREZGENE
  ENSHGLT00000007536 ENTREZGENE
InterPro Mediator_comp_sub12 UniProtKB/TrEMBL
  Mediator_Med12 UniProtKB/TrEMBL
  Mediator_Med12_catenin-bd UniProtKB/TrEMBL
  Mediator_Med12_LCEWAV UniProtKB/TrEMBL
NCBI Gene Med12 ENTREZGENE
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 UniProtKB/TrEMBL
  MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 UniProtKB/TrEMBL
Pfam Med12 UniProtKB/TrEMBL
  Med12-LCEWAV UniProtKB/TrEMBL
  Med12-PQL UniProtKB/TrEMBL
SMART Med12 UniProtKB/TrEMBL
UniProt G5BW30 ENTREZGENE, UniProtKB/TrEMBL