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Gene: Med12 (mediator complex subunit 12) Heterocephalus glaber

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Symbol:

Med12

Name:

mediator complex subunit 12

RGD ID:

18933796

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); embryonic neurocranium morphogenesis (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); angiosarcoma (ortholog); FOUND IN CKM complex (ortholog); ubiquitin ligase complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mediator of RNA polymerase II transcription subunit 12

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624903	1,412,474 - 1,436,474 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624903	1,412,346 - 1,436,474 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	leiomyosarcoma		ISO	MED12 (Homo sapiens)	9068941	DNA:missense mutations:cds:	RGD	PMID:26891131 and REF_RGD_ID:11353203
Med12	Naked Mole-Rat	major depressive disorder		ISO	MED12 (Homo sapiens)	9068941	DNA:mutation:multiple	RGD	PMID:12216017 and REF_RGD_ID:1358728
Med12	Naked Mole-Rat	phobic disorder		ISO	MED12 (Homo sapiens)	9068941	DNA:mutation:multiple	RGD	PMID:12216017 and REF_RGD_ID:1358728
Med12	Naked Mole-Rat	X-Linked Intellectual Developmental Disorders		ISO	MED12 (Homo sapiens)	9068941	DNA:missense mutation:cds:2881C>T(p.R961W)(human)	RGD	PMID:17334363 and REF_RGD_ID:12910952
Med12	Naked Mole-Rat	X-Linked Intellectual Developmental Disorders		ISO	MED12 (Homo sapiens)	9068941	DNA:duplication mutation:cds:c.5898dupC(p.S1967Qfs84)(human)	RGD	PMID:24039113 and REF_RGD_ID:12910947

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	Agenesis of Corpus Callosum		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Corpus callosum agenesis	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	angiosarcoma		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Angiosarcoma	ClinVar	PMID:26822237
Med12	Naked Mole-Rat	Anorectal Malformations		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Anorectal stenosis	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	autistic disorder		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism	ClinVar	PMID:21681106 and PMID:30208311
Med12	Naked Mole-Rat	autosomal hemophilia A		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA A	ClinVar	PMID:31690835
Med12	Naked Mole-Rat	autosomal recessive dyskeratosis congenita 5		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita and autosomal recessive 5	ClinVar	PMID:20301719 more ...
Med12	Naked Mole-Rat	Developmental Disabilities		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Global developmental delay	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	dilated cardiomyopathy 1Y		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dilated cardiomyopathy 1Y	ClinVar	PMID:28492532
Med12	Naked Mole-Rat	Ehlers-Danlos syndrome classic type 1		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Ehlers-Danlos syndrome and classic type	ClinVar	PMID:28492532
Med12	Naked Mole-Rat	factor VIII deficiency		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Factor 8 deficiency and congenital	ClinVar	PMID:31690835
Med12	Naked Mole-Rat	FG syndrome		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	FG Syndrome 1		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: FG syndrome 1	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	genetic disease		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	glioblastoma		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Glioblastoma	ClinVar	PMID:26822237
Med12	Naked Mole-Rat	Hardikar Syndrome		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:20301719 more ...
Med12	Naked Mole-Rat	imperforate anus		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Anal atresia	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	intellectual disability		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	nephroblastoma		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:25741868 and PMID:26822237
Med12	Naked Mole-Rat	Ohdo Syndrome, X-Linked		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	Simpson-Golabi-Behmel syndrome type 1		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Simpson-Golabi-Behmel syndrome type 1	ClinVar	PMID:25741868
Med12	Naked Mole-Rat	syndromic X-linked intellectual disability Lubs type		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs type	ClinVar	PMID:25741868
Med12	Naked Mole-Rat	syndromic X-linked intellectual disorder Lujan-Fryns-type		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	thoracic aortic aneurysm		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	thoracic aortic aneurysm		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	thoracic aortic aneurysm		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:10405444 more ...
Med12	Naked Mole-Rat	thoracic aortic aneurysm		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:17576681 more ...
Med12	Naked Mole-Rat	thoracic aortic aneurysm		ISO	MED12 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:17576681 more ...
Med12	Naked Mole-Rat	uterine fibroid		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Uterine leiomyoma	ClinVar	PMID:26822237
Med12	Naked Mole-Rat	X-linked severe combined immunodeficiency		ISO	MED12 (Homo sapiens)	8554872	ClinVar Annotator: match by term: X-linked severe combined immunodeficiency	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	adrenocortical carcinoma		ISO	MED12 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:24747642
Med12	Naked Mole-Rat	Breast Neoplasms		ISO	MED12 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25038752 and PMID:26437033
Med12	Naked Mole-Rat	Fibroadenoma		ISO	MED12 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25038752 and PMID:26437033
Med12	Naked Mole-Rat	Ohdo syndrome		ISO	MED12 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD
Med12	Naked Mole-Rat	Phyllodes Tumor		ISO	MED12 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:26437033
Med12	Naked Mole-Rat	Prostatic Neoplasms		ISO	MED12 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22610119 and PMID:29610475

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	FG Syndrome 1		ISO	MED12 (Homo sapiens)	7240710		OMIM
Med12	Naked Mole-Rat	Hardikar Syndrome		ISO	MED12 (Homo sapiens)	7240710		OMIM
Med12	Naked Mole-Rat	Ohdo Syndrome, X-Linked		ISO	MED12 (Homo sapiens)	7240710		OMIM
Med12	Naked Mole-Rat	syndromic X-linked intellectual disorder Lujan-Fryns-type		ISO	MED12 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	axis elongation involved in somitogenesis	acts_upstream_of_or_within	ISO	MGI:4839484	9068941	PMID:20630950	MGI	PMID:20630950
Med12	Naked Mole-Rat	embryonic brain development	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	embryonic neurocranium morphogenesis	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	embryonic organ development	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	endoderm development	acts_upstream_of_or_within	ISO	MGI:4839486	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	heart development	acts_upstream_of_or_within	ISO	MGI:4839484	9068941	PMID:20630950	MGI	PMID:20630950
Med12	Naked Mole-Rat	neural tube closure	acts_upstream_of_or_within	ISO	MGI:4839484	9068941	PMID:20630950	MGI	PMID:20630950
Med12	Naked Mole-Rat	neural tube development	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	oligodendrocyte development	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:23575864	MGI	PMID:23575864
Med12	Naked Mole-Rat	positive regulation of DNA-templated transcription	involved_in	ISO	MED12 (Homo sapiens)	9068941	PMID:10198638	UniProt	PMID:10198638
Med12	Naked Mole-Rat	positive regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	ISO	MED12 (Homo sapiens)	9068941	PMID:12037571	MGI	PMID:12037571
Med12	Naked Mole-Rat	positive regulation of transcription by RNA polymerase II	involved_in	IEA	PANTHER:PTN000300815 and PANTHER:PTN001400486	150520179		TreeGrafter	GO_REF:0000118
Med12	Naked Mole-Rat	positive regulation of transcription initiation by RNA polymerase II	involved_in	ISO	MED12 (Homo sapiens)	9068941	PMID:12218053	UniProt	PMID:12218053
Med12	Naked Mole-Rat	post-anal tail morphogenesis	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	protein ubiquitination		ISO	Med12 (Rattus norvegicus)	9068941		RGD	PMID:12149480 and REF_RGD_ID:2304264
Med12	Naked Mole-Rat	regulation of transcription by RNA polymerase II	involved_in	IEA	InterPro:IPR019035	150520179		InterPro	GO_REF:0000002
Med12	Naked Mole-Rat	Schwann cell development	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:23575864	MGI	PMID:23575864
Med12	Naked Mole-Rat	somatic stem cell population maintenance	acts_upstream_of_or_within	ISO	Med12 (Mus musculus)	9068941	PMID:20720539	MGI	PMID:20720539
Med12	Naked Mole-Rat	somitogenesis	acts_upstream_of_or_within	ISO	MGI:4839486	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	spinal cord development	acts_upstream_of_or_within	ISO	MGI:4839485	9068941	PMID:20589884	MGI	PMID:20589884
Med12	Naked Mole-Rat	Wnt signaling pathway, planar cell polarity pathway	acts_upstream_of_or_within	ISO	MGI:4839486	9068941	PMID:20630950	MGI	PMID:20630950

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	CKM complex	part_of	ISO	MED12 (Homo sapiens)	9068941	PMID:19047373	ComplexPortal	PMID:19047373
Med12	Naked Mole-Rat	mediator complex	part_of	IEA	InterPro:IPR019035 and InterPro:IPR021989	150520179		InterPro	GO_REF:0000002
Med12	Naked Mole-Rat	mediator complex	part_of	IEA	PANTHER:PTN000300815 and PANTHER:PTN001400486	150520179		TreeGrafter	GO_REF:0000118
Med12	Naked Mole-Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
Med12	Naked Mole-Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
Med12	Naked Mole-Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
Med12	Naked Mole-Rat	ubiquitin ligase complex		ISO	Med12 (Rattus norvegicus)	9068941		RGD	PMID:12149480 and REF_RGD_ID:2304264

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	beta-catenin binding	enables	IEA	InterPro:IPR021989	150520179		InterPro	GO_REF:0000002
Med12	Naked Mole-Rat	chromatin binding	enables	ISO	Med12 (Mus musculus)	9068941	PMID:20720539	MGI	PMID:20720539
Med12	Naked Mole-Rat	nuclear thyroid hormone receptor binding	enables	ISO	MED12 (Homo sapiens)	9068941	PMID:10198638	UniProt	PMID:10198638
Med12	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:Q8R3L8	9068941	PMID:20720539 and PMID:25344755	IntAct	PMID:20720539 and PMID:25344755
Med12	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:P05067 more ...	9068941	PMID:21293490	IntAct	PMID:21293490
Med12	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:Q99698	9068941	PMID:11984006	UniProt	PMID:11984006
Med12	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:P10071	9068941	PMID:17000779	UniProt	PMID:17000779
Med12	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:Q9NPJ6	9068941	PMID:25281560 more ...	IntAct	PMID:25281560 more ...
Med12	Naked Mole-Rat	protein binding	enables	ISO	UniProtKB:P37173	9068941	PMID:23178117	IntAct	PMID:23178117
Med12	Naked Mole-Rat	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	ISO	Med12 (Mus musculus)	9068941	PMID:23575864	MGI	PMID:23575864
Med12	Naked Mole-Rat	transcription coactivator activity	enables	IEA	PANTHER:PTN000300815 and PANTHER:PTN001400486	150520179		TreeGrafter	GO_REF:0000118
Med12	Naked Mole-Rat	transcription coregulator activity	enables	IEA	InterPro:IPR019035	150520179		InterPro	GO_REF:0000002
Med12	Naked Mole-Rat	ubiquitin protein ligase activity	contributes_to	ISO	Med12 (Rattus norvegicus)	9068941		RGD	PMID:12149480 and REF_RGD_ID:2304264

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Med12	Naked Mole-Rat	RNA polymerase II transcription pathway		ISO	MED12 (Homo sapiens)	9068941		RGD	PMID:24088064 and REF_RGD_ID:9681732

PMID:22301074	PMID:30032202

Med12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624903	1,412,474 - 1,436,474 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624903	1,412,346 - 1,436,474 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

MED12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	71,118,596 - 71,142,450 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	71,118,543 - 71,144,103 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	70,338,446 - 70,362,300 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	70,255,131 - 70,279,029 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	70,121,593 - 70,145,168	NCBI
Celera	X	70,692,310 - 70,716,179 (+)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	64,157,722 - 64,181,176 (+)	NCBI		HuRef
CHM1_1	X	70,231,161 - 70,255,024 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	69,551,517 - 69,576,535 (+)	NCBI		T2T-CHM13v2.0

Med12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	100,317,697 - 100,342,540 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	100,317,636 - 100,341,071 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	101,274,091 - 101,298,934 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	101,274,030 - 101,297,465 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	98,469,430 - 98,494,273 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	97,477,613 - 97,499,990 (+)	NCBI		MGSCv36	mm8
Celera	X	88,190,265 - 88,214,981 (+)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	43.91	NCBI

Med12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	70,444,615 - 70,467,780 (+)	NCBI		GRCr8
mRatBN7.2	X	66,404,807 - 66,427,775 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	66,404,760 - 66,428,387 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,888,182 - 67,911,125 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	71,388,570 - 71,411,513 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	68,949,477 - 68,972,420 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	71,174,653 - 71,197,812 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	71,174,699 - 71,197,812 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	72,027,135 - 72,050,293 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	89,351,546 - 89,374,489 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	66,760,730 - 66,783,673 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

Med12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955475	10,687,367 - 10,710,053 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955475	10,687,168 - 10,710,286 (+)	NCBI	ChiLan1.0	ChiLan1.0

MED12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	70,795,965 - 70,819,857 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	70,799,572 - 70,823,460 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	60,386,820 - 60,410,730 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	70,443,467 - 70,467,178 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	70,443,667 - 70,466,942 (+)	Ensembl	panpan1.1		panPan2

MED12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	55,487,629 - 55,508,941 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	55,482,013 - 55,509,992 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	46,314,714 - 46,337,057 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	56,456,534 - 56,465,517 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	54,424,767 - 54,447,085 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	55,756,191 - 55,778,506 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	55,683,336 - 55,705,668 (+)	NCBI		UU_Cfam_GSD_1.0

Med12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	46,697,933 - 46,721,139 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936762	460,342 - 483,195 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936762	460,342 - 483,264 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MED12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	57,150,919 - 57,175,333 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	57,150,884 - 57,174,367 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	64,681,038 - 64,704,523 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MED12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	60,915,796 - 60,939,220 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	60,915,703 - 60,937,677 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	2,776,278 - 2,799,983 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_004872632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_004872633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250530	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021250540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01102126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSHGLT00000007535 ⟹ ENSHGLP00000007450

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624903	1,412,474 - 1,436,474 (+)	Ensembl

Ensembl Acc Id:

ENSHGLT00000007536 ⟹ ENSHGLP00000007451

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624903	1,412,537 - 1,436,241 (+)	Ensembl

RefSeq Acc Id:

XM_004872632 ⟹ XP_004872689

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,352 - 1,436,391 (+)	NCBI

RefSeq Acc Id:

XM_004872633 ⟹ XP_004872690

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,351 - 1,436,391 (+)	NCBI

RefSeq Acc Id:

XM_021250526 ⟹ XP_021106185

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,349 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250527 ⟹ XP_021106186

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,348 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250528 ⟹ XP_021106187

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,348 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250529 ⟹ XP_021106188

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,350 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250530 ⟹ XP_021106189

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,350 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250531 ⟹ XP_021106190

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,347 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250532 ⟹ XP_021106191

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,346 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250533 ⟹ XP_021106192

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,346 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250535 ⟹ XP_021106194

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,515 - 1,436,474 (+)	NCBI

RefSeq Acc Id:

XM_021250536 ⟹ XP_021106195

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,350 - 1,436,391 (+)	NCBI

RefSeq Acc Id:

XM_021250537 ⟹ XP_021106196

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,350 - 1,436,391 (+)	NCBI

RefSeq Acc Id:

XM_021250538 ⟹ XP_021106197

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,349 - 1,436,391 (+)	NCBI

RefSeq Acc Id:

XM_021250539 ⟹ XP_021106198

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,351 - 1,436,391 (+)	NCBI

RefSeq Acc Id:

XM_021250540 ⟹ XP_021106199

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624903	1,412,350 - 1,436,391 (+)	NCBI


Protein RefSeqs	XP_004872689	(Get FASTA)	NCBI Sequence Viewer
	XP_004872690	(Get FASTA)	NCBI Sequence Viewer
	XP_021106185	(Get FASTA)	NCBI Sequence Viewer
	XP_021106186	(Get FASTA)	NCBI Sequence Viewer
	XP_021106187	(Get FASTA)	NCBI Sequence Viewer
	XP_021106188	(Get FASTA)	NCBI Sequence Viewer
	XP_021106189	(Get FASTA)	NCBI Sequence Viewer
	XP_021106190	(Get FASTA)	NCBI Sequence Viewer
	XP_021106191	(Get FASTA)	NCBI Sequence Viewer
	XP_021106192	(Get FASTA)	NCBI Sequence Viewer
	XP_021106194	(Get FASTA)	NCBI Sequence Viewer
	XP_021106195	(Get FASTA)	NCBI Sequence Viewer
	XP_021106196	(Get FASTA)	NCBI Sequence Viewer
	XP_021106197	(Get FASTA)	NCBI Sequence Viewer
	XP_021106198	(Get FASTA)	NCBI Sequence Viewer
	XP_021106199	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSHGLP00000007450
	ENSHGLP00000007451

RefSeq Acc Id:	XP_021106191 ⟸ XM_021250532
- Peptide Label:	isoform X7
- UniProtKB:	G5BW30 (UniProtKB/TrEMBL), A0AAX6SCC9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021106192 ⟸ XM_021250533
- Peptide Label:	isoform X8
- UniProtKB:	G5BW30 (UniProtKB/TrEMBL), A0AAX6SDV5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021106190 ⟸ XM_021250531
- Peptide Label:	isoform X6
- UniProtKB:	G5BW30 (UniProtKB/TrEMBL), A0AAX6SCP0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021106186 ⟸ XM_021250527
- Peptide Label:	isoform X2
- UniProtKB:	G5BW30 (UniProtKB/TrEMBL), A0AAX6SA36 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021106187 ⟸ XM_021250528
- Peptide Label:	isoform X3
- UniProtKB:	G5BW30 (UniProtKB/TrEMBL), A0AAX6SB56 (UniProtKB/TrEMBL)

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000005421	Ensembl, ENTREZGENE
Ensembl Transcript	ENSHGLT00000007535	ENTREZGENE
	ENSHGLT00000007536	ENTREZGENE
InterPro	Mediator_comp_sub12	UniProtKB/TrEMBL
	Mediator_Med12	UniProtKB/TrEMBL
	Mediator_Med12_catenin-bd	UniProtKB/TrEMBL
	Mediator_Med12_LCEWAV	UniProtKB/TrEMBL
NCBI Gene	Med12	ENTREZGENE
PANTHER	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12	UniProtKB/TrEMBL
	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12	UniProtKB/TrEMBL
Pfam	Med12	UniProtKB/TrEMBL
	Med12-LCEWAV	UniProtKB/TrEMBL
	Med12-PQL	UniProtKB/TrEMBL
SMART	Med12	UniProtKB/TrEMBL
UniProt	A0AAX6QDH9	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6QE50	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6S827	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6S9T5	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SA36	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SAL2	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SB56	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SBD1	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SBQ5	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SBU7	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SCC9	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SCI8	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SCP0	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SDV5	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SDW2	ENTREZGENE, UniProtKB/TrEMBL
	A0AAX6SEK4	ENTREZGENE, UniProtKB/TrEMBL
	G5BW30	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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