MED12 (mediator complex subunit 12) - Rat Genome Database

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Gene: MED12 (mediator complex subunit 12) Pan paniscus
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Symbol: MED12
Name: mediator complex subunit 12
RGD ID: 11770947
Description: ENCODES a protein that exhibits chromatin binding (ortholog); protein C-terminus binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN axis elongation involved in somitogenesis (ortholog); canonical Wnt signaling pathway (ortholog); embryonic brain development (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); angiosarcoma (ortholog); FOUND IN mediator complex (ortholog); nucleus (ortholog); ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: mediator of RNA polymerase II transcription subunit 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X70,443,467 - 70,467,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,443,667 - 70,466,942 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
MED12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X70,443,467 - 70,467,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,443,667 - 70,466,942 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBIMhudiblu_PPA_v0panPan3
MED12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX71,118,556 - 71,142,454 (+)EnsemblGRCh38hg38GRCh38
GRCh38X71,118,596 - 71,142,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,338,446 - 70,362,300 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,255,131 - 70,279,029 (+)NCBINCBI36hg18NCBI36
Build 34X70,121,593 - 70,145,168NCBI
CeleraX70,692,310 - 70,716,179 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,157,722 - 64,181,176 (+)NCBIHuRef
CHM1_1X70,231,161 - 70,255,024 (+)NCBICHM1_1
Med12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,317,697 - 100,342,540 (+)NCBIGRCm39mm39
GRCm39 EnsemblX100,317,636 - 100,341,071 (+)Ensembl
GRCm38X101,274,091 - 101,298,934 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,274,030 - 101,297,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X98,469,430 - 98,494,273 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X97,477,613 - 97,499,990 (+)NCBImm8
CeleraX88,190,265 - 88,214,981 (+)NCBICelera
Cytogenetic MapXDNCBI
Med12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X66,404,622 - 66,427,772 (+)NCBI
Rnor_6.0 EnsemblX71,174,699 - 71,197,812 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X71,174,653 - 71,197,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X72,027,135 - 72,050,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,351,546 - 89,374,489 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX66,760,730 - 66,783,673 (+)NCBICelera
Cytogenetic MapXq22NCBI
Med12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547510,687,367 - 10,710,053 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547510,687,168 - 10,710,286 (+)NCBIChiLan1.0ChiLan1.0
MED12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,487,629 - 55,508,941 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,482,013 - 55,509,992 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX46,314,714 - 46,337,057 (+)NCBI
ROS_Cfam_1.0X56,456,534 - 56,465,517 (+)NCBI
UMICH_Zoey_3.1X54,424,767 - 54,447,085 (+)NCBI
UNSW_CanFamBas_1.0X55,756,191 - 55,778,506 (+)NCBI
UU_Cfam_GSD_1.0X55,683,336 - 55,705,668 (+)NCBI
Med12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,697,933 - 46,721,139 (-)NCBI
SpeTri2.0NW_004936762460,342 - 483,264 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX57,150,578 - 57,175,352 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X57,150,884 - 57,174,367 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X64,681,038 - 64,704,523 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MED12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,915,796 - 60,939,220 (+)NCBI
ChlSab1.1 EnsemblX60,915,703 - 60,937,677 (+)Ensembl
Med12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249031,412,346 - 1,436,474 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000041914   ⟹   ENSPPAP00000019163
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX70,443,667 - 70,466,942 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041926   ⟹   ENSPPAP00000019175
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX70,443,667 - 70,466,190 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000041950   ⟹   ENSPPAP00000019198
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX70,443,667 - 70,466,190 (+)Ensembl
RefSeq Acc Id: XM_003820143   ⟹   XP_003820191
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X70,443,467 - 70,467,178 (+)NCBI
Mhudiblu_PPA_v0X60,386,821 - 60,410,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973560   ⟹   XP_008971808
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X70,443,467 - 70,467,178 (+)NCBI
Mhudiblu_PPA_v0X60,386,821 - 60,410,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973561   ⟹   XP_008971809
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X70,443,467 - 70,467,178 (+)NCBI
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034950177   ⟹   XP_034806068
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBI
RefSeq Acc Id: XM_034950178   ⟹   XP_034806069
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBI
RefSeq Acc Id: XM_034950179   ⟹   XP_034806070
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBI
RefSeq Acc Id: XM_034950180   ⟹   XP_034806071
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0X60,386,820 - 60,410,730 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_008971808   ⟸   XM_008973560
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008971809   ⟸   XM_008973561
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_003820191   ⟸   XM_003820143
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034806068   ⟸   XM_034950177
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034806071   ⟸   XM_034950180
- Peptide Label: isoform X7
RefSeq Acc Id: XP_034806069   ⟸   XM_034950178
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034806070   ⟸   XM_034950179
- Peptide Label: isoform X5
RefSeq Acc Id: ENSPPAP00000019175   ⟸   ENSPPAT00000041926
RefSeq Acc Id: ENSPPAP00000019198   ⟸   ENSPPAT00000041950
RefSeq Acc Id: ENSPPAP00000019163   ⟸   ENSPPAT00000041914
Protein Domains
Med12


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032699 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000019163 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000019175 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000019198 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041914 UniProtKB/TrEMBL
  ENSPPAT00000041926 UniProtKB/TrEMBL
  ENSPPAT00000041950 UniProtKB/TrEMBL
InterPro Mediator_Med12 UniProtKB/TrEMBL
  Mediator_Med12_catenin-bd UniProtKB/TrEMBL
  Mediator_Med12_LCEWAV UniProtKB/TrEMBL
KEGG Report pps:100993721 UniProtKB/TrEMBL
NCBI Gene MED12 ENTREZGENE
Pfam Med12 UniProtKB/TrEMBL
  Med12-LCEWAV UniProtKB/TrEMBL
  Med12-PQL UniProtKB/TrEMBL
SMART Med12 UniProtKB/TrEMBL
UniProt A0A2R9APR5_PANPA UniProtKB/TrEMBL
  A0A2R9APV7_PANPA UniProtKB/TrEMBL
  A0A2R9ATR2_PANPA UniProtKB/TrEMBL