Cnga2 (cyclic nucleotide gated channel subunit alpha 2) - Rat Genome Database

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Gene: Cnga2 (cyclic nucleotide gated channel subunit alpha 2) Heterocephalus glaber
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Symbol: Cnga2
Name: cyclic nucleotide gated channel subunit alpha 2
RGD ID: 18921862
Description: ENCODES a protein that exhibits cGMP binding (ortholog); identical protein binding (ortholog); intracellularly cAMP-activated cation channel activity (ortholog); INVOLVED IN calcium ion transport (ortholog); membrane depolarization (ortholog); potassium ion transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH cervical cancer (ortholog); FOUND IN intracellular cyclic nucleotide activated cation channel complex (ortholog); non-motile cilium membrane (ortholog); perikaryon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclic nucleotide gated channel alpha 2; Cyclic nucleotide-gated olfactory channel
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248833,043,661 - 3,051,420 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248833,043,666 - 3,049,801 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal EnsemblX3,044,427 - 3,063,520 (+)Ensembl
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Cnga2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248833,043,661 - 3,051,420 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248833,043,666 - 3,049,801 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal EnsemblX3,044,427 - 3,063,520 (+)Ensembl
CNGA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X151,734,746 - 151,745,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX151,734,746 - 151,745,564 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37X150,903,218 - 150,914,036 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X150,653,874 - 150,664,692 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X150,573,785 - 150,584,604NCBI
CeleraX151,151,573 - 151,162,391 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX139,760,197 - 139,771,472 (+)NCBIHuRef
CHM1_1X150,778,166 - 150,789,044 (+)NCBICHM1_1
T2T-CHM13v2.0X150,003,054 - 150,013,922 (+)NCBIT2T-CHM13v2.0
Cnga2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X71,035,455 - 71,053,824 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX71,035,455 - 71,053,824 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X71,991,849 - 72,010,218 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX71,991,849 - 72,010,218 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37X69,237,214 - 69,255,557 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X68,244,595 - 68,262,938 (+)NCBIMGSCv36mm8
CeleraX62,970,984 - 62,989,303 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.15NCBI
Cnga2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X154,741,742 - 154,759,814 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX154,741,764 - 154,759,814 (+)EnsemblGRCr8
mRatBN7.2X149,696,999 - 149,715,051 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX149,696,997 - 149,715,051 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX151,891,155 - 151,909,199 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X155,425,353 - 155,443,396 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X152,966,917 - 152,984,966 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01669,878,513 - 69,899,075 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,243,659 - 69,246,983 (-)NCBIRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01669,549,195 - 69,554,983 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0170,646,269 - 70,664,968 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X157,558,962 - 157,575,781NCBIRGSC_v3.4RGSC_v3.4rn4
RGSC_v3.1X157,632,395 - 157,649,214NCBI
Cytogenetic MapXq37NCBI
Cnga2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554987,250,514 - 7,257,701 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554987,250,514 - 7,257,701 (+)NCBIChiLan1.0ChiLan1.0
CNGA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X151,806,407 - 151,813,245 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X151,810,012 - 151,816,850 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X141,315,052 - 141,324,754 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X151,272,051 - 151,281,909 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX151,275,800 - 151,281,909 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
CNGA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X119,695,898 - 119,702,791 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX119,695,898 - 119,702,446 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX105,078,713 - 105,085,373 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X121,916,523 - 121,923,183 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX121,916,523 - 121,922,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X118,636,774 - 118,643,434 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X121,119,721 - 121,126,381 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X121,002,320 - 121,008,981 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cnga2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1X3,502,915 - 3,509,238 (-)NCBImIctTri1.hap1
HiC_Itri_2X117,230,525 - 117,245,175 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367141,011,736 - 1,017,729 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367141,011,736 - 1,017,722 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNGA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX123,115,975 - 123,129,840 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X123,115,980 - 123,130,043 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CNGA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1X4,148,549 - 4,154,454 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366606564,080,980 - 64,090,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1X126,277,931 - 126,302,167 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX126,295,236 - 126,301,141 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Cnga2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v113207,995 - 214,638 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000002811   ⟹   ENSHGLP00000002757
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248833,043,666 - 3,049,801 (+)Ensembl
Naked mole-rat maternal EnsemblX3,044,427 - 3,063,520 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000003592   ⟹   ENSHGLP00000003537
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
Naked mole-rat maternal EnsemblX3,044,485 - 3,047,747 (+)Ensembl
RefSeq Acc Id: XM_004871075   ⟹   XP_004871132
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248833,043,661 - 3,051,420 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004871132 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB18680 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002757
RefSeq Acc Id: XP_004871132   ⟸   XM_004871075
- UniProtKB: G5CAW9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000002757   ⟸   ENSHGLT00000002811
Ensembl Acc Id: ENSHGLP00000003537   ⟸   ENSHGLT00000003592


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002074 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000002811 ENTREZGENE
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.5.300 UniProtKB/TrEMBL
  2.60.120.10 UniProtKB/TrEMBL
  Helix hairpin bin UniProtKB/TrEMBL
InterPro CLZ_dom UniProtKB/TrEMBL
  CNG_Cation_Channel UniProtKB/TrEMBL
  cNMP-bd-like UniProtKB/TrEMBL
  cNMP-bd_CS UniProtKB/TrEMBL
  cNMP-bd_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
KEGG Report hgl:101721848 UniProtKB/TrEMBL
NCBI Gene Cnga2 ENTREZGENE
PANTHER CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A UniProtKB/TrEMBL
  CYCLIC NUCLEOTIDE-GATED OLFACTORY CHANNEL UniProtKB/TrEMBL
Pfam CLZ UniProtKB/TrEMBL
  cNMP_binding UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PROSITE CNMP_BINDING_1 UniProtKB/TrEMBL
  CNMP_BINDING_2 UniProtKB/TrEMBL
  CNMP_BINDING_3 UniProtKB/TrEMBL
SMART cNMP UniProtKB/TrEMBL
Superfamily-SCOP SSF51206 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt G5CAW9 ENTREZGENE, UniProtKB/TrEMBL