Tfam (transcription factor A, mitochondrial) - Rat Genome Database

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Gene: Tfam (transcription factor A, mitochondrial) Heterocephalus glaber
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Symbol: Tfam
Name: transcription factor A, mitochondrial
RGD ID: 18908766
Description: ENCODES a protein that exhibits chromatin binding (ortholog); heat shock protein binding (ortholog); mitochondrial promoter sequence-specific DNA binding (ortholog); INVOLVED IN mitochondrial respiratory chain complex assembly (ortholog); mitochondrial transcription (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); Animal Disease Models (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247915,179,195 - 5,198,611 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247915,183,276 - 5,198,986 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tfam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247915,179,195 - 5,198,611 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247915,183,276 - 5,198,986 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TFAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381058,385,410 - 58,399,220 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1058,385,345 - 58,399,220 (+)EnsemblGRCh38hg38GRCh38
GRCh371060,145,170 - 60,158,980 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361059,815,182 - 59,825,903 (+)NCBINCBI36Build 36hg18NCBI36
Celera1053,410,112 - 53,420,833 (+)NCBICelera
Cytogenetic Map10q21.1NCBI
HuRef1054,133,767 - 54,148,729 (+)NCBIHuRef
CHM1_11060,426,687 - 60,440,776 (+)NCBICHM1_1
T2T-CHM13v2.01059,239,514 - 59,253,326 (+)NCBIT2T-CHM13v2.0
Tfam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391071,061,298 - 71,074,157 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1071,061,294 - 71,074,110 (-)EnsemblGRCm39 Ensembl
GRCm381071,225,468 - 71,238,328 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1071,225,464 - 71,238,280 (-)EnsemblGRCm38mm10GRCm38
MGSCv371070,688,225 - 70,700,792 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361070,620,777 - 70,633,344 (-)NCBIMGSCv36mm8
Celera1072,300,895 - 72,313,462 (-)NCBICelera
Cytogenetic Map10B5.3NCBI
cM Map1036.83NCBI
Tfam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82017,355,373 - 17,367,422 (+)NCBIGRCr8
mRatBN7.22017,356,243 - 17,368,293 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2017,356,197 - 17,368,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2018,082,918 - 18,094,966 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02017,437,916 - 17,449,964 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02017,910,581 - 17,922,629 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02018,594,057 - 18,606,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2018,594,037 - 18,606,151 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02020,760,402 - 20,772,301 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42018,100,629 - 18,112,682 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12018,114,428 - 18,126,482 (+)NCBI
Celera2018,754,951 - 18,766,964 (+)NCBICelera
Cytogenetic Map20p11NCBI
Tfam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542512,106,877 - 12,120,782 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542512,106,506 - 12,121,625 (+)NCBIChiLan1.0ChiLan1.0
TFAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2870,594,983 - 70,606,152 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11070,600,391 - 70,611,474 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01054,917,578 - 54,934,124 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11057,137,911 - 57,152,102 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1057,138,437 - 57,147,972 (+)Ensemblpanpan1.1panPan2
TFAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1410,585,320 - 10,600,664 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl410,585,480 - 10,598,058 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha410,777,843 - 10,794,098 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0410,841,889 - 10,857,973 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl410,842,146 - 10,857,106 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1410,826,103 - 10,842,176 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0410,945,723 - 10,961,973 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0411,254,972 - 11,271,059 (+)NCBIUU_Cfam_GSD_1.0
Tfam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721370,510,063 - 70,519,044 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366144,596,617 - 4,605,104 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366144,595,973 - 4,605,040 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1492,259,403 - 92,279,731 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11492,261,713 - 92,279,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214100,777,168 - 100,778,350 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TFAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1972,900,665 - 72,914,634 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl972,904,637 - 72,914,397 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604833,803,050 - 33,817,151 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013049   ⟹   ENSHGLP00000012912
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247915,179,195 - 5,198,611 (-)Ensembl
RefSeq Acc Id: XM_004858304   ⟹   XP_004858361
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247915,183,276 - 5,198,986 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004858361 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012912
  ENSHGLP00100058461
GenBank Protein JAN98261 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004858361   ⟸   XM_004858304
- UniProtKB: A0A0N8ET49 (UniProtKB/TrEMBL),   G5BLB7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000012912   ⟸   ENSHGLT00000013049


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009231 Ensembl, ENTREZGENE
  ENSHGLG00100041177 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000013049 ENTREZGENE
  ENSHGLT00100049597 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  HMGB UniProtKB/TrEMBL
KEGG Report hgl:101698418 UniProtKB/TrEMBL
NCBI Gene Tfam ENTREZGENE
PANTHER HIGH MOBILITY GROUP PROTEIN DSP1 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR A, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
  HMG_box_2 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A0N8ET49 ENTREZGENE, UniProtKB/TrEMBL
  G5BLB7 ENTREZGENE, UniProtKB/TrEMBL