Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | multiple interactions | ISO | Fam114a1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of FAM114A1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of FAM114A1 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM114A1 mRNA | CTD | PMID:33387578 | 2-hydroxypropanoic acid | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of FAM114A1 mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of FAM114A1 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases methylation | ISO | FAM114A1 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of FAM114A1 gene | CTD | PMID:31601247 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of FAM114A1 mRNA | CTD | PMID:28973697 | 5-fluorouracil | affects expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Fluorouracil affects the expression of FAM114A1 mRNA | CTD | PMID:16584549 | acrolein | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of FAM114A1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of FAM114A1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | FAM114A1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FAM114A1 gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of FAM114A1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of FAM114A1 mRNA | CTD | PMID:32699268 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of FAM114A1 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FAM114A1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | FAM114A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FAM114A1 5' UTR | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of FAM114A1 protein | CTD | PMID:31163220 | bis(2-ethylhexyl) phthalate | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of FAM114A1 mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FAM114A1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of FAM114A1 protein | CTD | PMID:34186270 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FAM114A1 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of FAM114A1 mRNA | CTD | PMID:30951980 | Bisphenol B | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of FAM114A1 protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of FAM114A1 mRNA | CTD | PMID:30951980 | carbon nanotube | affects expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of FAM114A1 mRNA | CTD | PMID:25554681 | chromium(6+) | affects expression | ISO | Fam114a1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of FAM114A1 mRNA | CTD | PMID:28472532 | clofibrate | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of FAM114A1 mRNA | CTD | PMID:23811191 | copper(II) sulfate | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of FAM114A1 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FAM114A1 mRNA | CTD | PMID:20106945 | cyproconazole | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | cyproconazole results in increased expression of FAM114A1 mRNA | CTD | PMID:22334560 | dexamethasone | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of FAM114A1 mRNA | CTD | PMID:22733784 | dibutyl phthalate | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of FAM114A1 mRNA | CTD | PMID:21266533 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of FAM114A1 mRNA | CTD | PMID:25152437 | dorsomorphin | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of FAM114A1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of FAM114A1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | entinostat results in increased expression of FAM114A1 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM114A1 mRNA | CTD | PMID:27188386 | epoxiconazole | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of FAM114A1 mRNA | CTD | PMID:22334560 | epoxiconazole | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of FAM114A1 mRNA | CTD | PMID:35436446 | ethanol | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Ethanol results in increased expression of FAM114A1 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of FAM114A1 mRNA | CTD | PMID:34813904 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of FAM114A1 mRNA | CTD | PMID:24136188 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of FAM114A1 mRNA | CTD | PMID:24136188 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of FAM114A1 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Fam114a1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22206623 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of FAM114A1 mRNA | CTD | PMID:24136188 | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of FAM114A1 gene | CTD | PMID:35440735 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22129741 | ivermectin | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of FAM114A1 protein | CTD | PMID:32959892 | N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22129741 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22129741 | ochratoxin A | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | ochratoxin A results in decreased expression of FAM114A1 mRNA | CTD | PMID:30559759 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of FAM114A1 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of FAM114A1 mRNA more ... | CTD | PMID:32699268 | paracetamol | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of FAM114A1 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FAM114A1 mRNA | CTD | PMID:33387578 | paracetamol | affects expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of FAM114A1 mRNA | CTD | PMID:17562736 | phenylmercury acetate | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of FAM114A1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM114A1 mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | Fam114a1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FAM114A1 mRNA | CTD | PMID:19710929 | potassium chromate | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FAM114A1 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM114A1 mRNA | CTD | PMID:22079256 | propiconazole | increases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | propiconazole results in increased expression of FAM114A1 mRNA | CTD | PMID:21278054 and PMID:22334560 | quercetin | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of FAM114A1 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of FAM114A1 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | affects expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of FAM114A1 mRNA | CTD | PMID:29319823 | sunitinib | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of FAM114A1 mRNA | CTD | PMID:31533062 | tetrachloromethane | affects expression | ISO | Fam114a1 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of FAM114A1 mRNA | CTD | PMID:17484886 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of FAM114A1 mRNA | CTD | PMID:25729387 | topotecan | increases expression | EXP | | 6480464 | Topotecan results in increased expression of FAM114A1 mRNA | CTD | PMID:25729387 | torcetrapib | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of FAM114A1 mRNA | CTD | PMID:23228038 | trichostatin A | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FAM114A1 mRNA | CTD | PMID:24935251 | triptonide | decreases expression | ISO | Fam114a1 (Mus musculus) | 6480464 | triptonide results in decreased expression of FAM114A1 mRNA | CTD | PMID:33045310 | urethane | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of FAM114A1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FAM114A1 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FAM114A1 mRNA | CTD | PMID:37505509 | valproic acid | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM114A1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FAM114A1 mRNA | CTD | PMID:19101580 more ... | vorinostat | multiple interactions | ISO | FAM114A1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM114A1 mRNA | CTD | PMID:27188386 | vorinostat | increases expression | ISO | FAM114A1 (Homo sapiens) | 6480464 | vorinostat results in increased expression of FAM114A1 mRNA | CTD | PMID:26272509 | |