WNT11 (Wnt family member 11) - Rat Genome Database

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Gene: WNT11 (Wnt family member 11) Sus scrofa
Analyze
Symbol: WNT11
Name: Wnt family member 11
RGD ID: 14243631
Description: ENCODES a protein that exhibits protein kinase activator activity (inferred); signaling receptor binding (inferred); INVOLVED IN apoptotic process (ortholog); artery morphogenesis (ortholog); bicellular tight junction assembly (ortholog); PARTICIPATES IN the Wnt/calcium signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Abnormalities, Drug-Induced (ortholog); Animal Disease Models (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); FOUND IN cytoplasm (inferred); extracellular matrix (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein Wnt-11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,413,263 - 10,435,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,413,182 - 10,435,158 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2911,487,189 - 11,509,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (IEA)
apoptotic process  (IEA,ISO)
artery morphogenesis  (IEA,ISO)
atrial septum development  (IEA)
bicellular tight junction assembly  (IEA,ISO)
bone mineralization  (IEA,ISO)
canonical Wnt signaling pathway  (IEA,ISO)
cell differentiation  (ISO)
cellular response to mechanical stimulus  (IEA,ISO)
cloacal septation  (IEA)
convergent extension involved in axis elongation  (IEA,ISO)
embryonic skeletal system development  (IEA)
epithelial cell apoptotic process  (IEA,ISO)
epithelial to mesenchymal transition  (IEA,ISO)
intracellular signal transduction  (IEA)
kidney development  (IEA,ISO)
lung-associated mesenchyme development  (IEA)
maintenance of epithelial cell apical/basal polarity  (IEA,ISO)
mesenchymal cell proliferation  (IEA,ISO)
mesonephric duct development  (IEA)
negative regulation of canonical Wnt signaling pathway  (IEA,ISO)
negative regulation of fibroblast growth factor production  (IEA,ISO)
negative regulation of mesenchymal cell proliferation  (IEA,ISO)
negative regulation of stem cell proliferation  (IEA,ISO)
neuroendocrine cell differentiation  (IEA)
non-canonical Wnt signaling pathway  (IEA,ISO)
notochord morphogenesis  (IEA,ISO)
osteoblast differentiation  (IEA,ISO)
outflow tract morphogenesis  (IEA,ISO)
paraxial mesoderm formation  (IEA,ISO)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of epithelial cell apoptotic process  (IEA,ISO)
positive regulation of transforming growth factor beta2 production  (IEA,ISO)
primary heart field specification  (IEA)
response to nutrient levels  (ISO)
roof of mouth development  (IEA,ISO)
secondary heart field specification  (IEA)
secondary palate development  (IEA)
signal transduction  (IEA)
somite development  (IEA,ISO)
stem cell proliferation  (IEA,ISO)
ureteric bud morphogenesis  (IEA)
ventricular septum development  (IEA)
ventricular septum morphogenesis  (IEA,ISO)
Wnt signaling pathway  (IEA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WNT11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl910,413,263 - 10,435,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1910,413,182 - 10,435,158 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2911,487,189 - 11,509,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WNT11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381176,186,325 - 76,210,761 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1176,186,325 - 76,210,736 (-)EnsemblGRCh38hg38GRCh38
GRCh371175,897,369 - 75,917,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361175,575,018 - 75,595,222 (-)NCBINCBI36Build 36hg18NCBI36
Build 341175,575,017 - 75,595,222NCBI
Celera1173,205,187 - 73,225,391 (-)NCBICelera
Cytogenetic Map11q13.5NCBI
HuRef1172,194,546 - 72,214,753 (-)NCBIHuRef
CHM1_11175,780,888 - 75,801,091 (-)NCBICHM1_1
T2T-CHM13v2.01176,116,041 - 76,140,519 (-)NCBIT2T-CHM13v2.0
Wnt11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39798,484,293 - 98,503,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl798,484,319 - 98,504,402 (+)EnsemblGRCm39 Ensembl
GRCm38798,835,084 - 98,854,747 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl798,835,112 - 98,855,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv377105,987,355 - 106,003,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36798,714,037 - 98,728,940 (+)NCBIMGSCv36mm8
Celera799,160,445 - 99,176,286 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map753.9NCBI
Wnt11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81162,545,660 - 162,565,456 (+)NCBIGRCr8
mRatBN7.21153,134,503 - 153,154,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1153,138,197 - 153,154,294 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1161,133,836 - 161,149,936 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,314,007 - 168,330,107 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01161,187,522 - 161,203,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01163,794,136 - 163,813,756 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1163,797,660 - 163,813,756 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,997,286 - 170,016,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,125,969 - 156,142,065 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11156,213,816 - 156,216,652 (+)NCBI
Celera1151,224,671 - 151,240,729 (+)NCBICelera
Cytogenetic Map1q32NCBI
Wnt11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541415,674,940 - 15,694,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541415,674,478 - 15,694,758 (+)NCBIChiLan1.0ChiLan1.0
WNT11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2977,110,987 - 77,161,434 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,156,064 - 78,180,195 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01171,239,781 - 71,263,915 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11174,540,025 - 74,560,024 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1174,540,169 - 74,560,024 (-)Ensemblpanpan1.1panPan2
WNT11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12122,442,496 - 22,463,040 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2122,446,051 - 22,463,173 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,210,200 - 22,227,251 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02122,648,822 - 22,665,821 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2122,648,814 - 22,665,904 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12122,423,226 - 22,440,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02122,642,741 - 22,659,738 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02122,561,731 - 22,578,745 (+)NCBIUU_Cfam_GSD_1.0
Wnt11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494763,309,313 - 63,329,371 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364984,908,978 - 4,927,165 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364984,909,041 - 4,927,482 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNT11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,393,975 - 67,427,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,399,074 - 67,418,509 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604358,377,747 - 58,402,147 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wnt11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624817932,970 - 952,326 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624817931,686 - 952,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in WNT11
664 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 4 13 3 5 14 12 13 3 5 1

Sequence


Ensembl Acc Id: ENSSSCT00000024218   ⟹   ENSSSCP00000019221
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl910,413,263 - 10,431,405 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000025742   ⟹   ENSSSCP00000024313
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl910,413,263 - 10,432,383 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000073379   ⟹   ENSSSCP00000070221
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl910,413,263 - 10,435,100 (-)Ensembl
RefSeq Acc Id: XM_005667138   ⟹   XP_005667195
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,413,182 - 10,435,158 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979148   ⟹   XP_013834602
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,413,182 - 10,434,400 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979149   ⟹   XP_013834603
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,413,182 - 10,434,804 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021062532   ⟹   XP_020918191
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1910,413,182 - 10,433,499 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005667195   ⟸   XM_005667138
- UniProtKB: A0A8D1MKJ5 (UniProtKB/TrEMBL),   A0A5G2QZA2 (UniProtKB/TrEMBL),   A0A4X1UK22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834603   ⟸   XM_013979149
- UniProtKB: A0A8D1MKJ5 (UniProtKB/TrEMBL),   A0A5G2QZA2 (UniProtKB/TrEMBL),   A0A4X1UK22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834602   ⟸   XM_013979148
- UniProtKB: A0A8D1MKJ5 (UniProtKB/TrEMBL),   A0A5G2QZA2 (UniProtKB/TrEMBL),   A0A4X1UK22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918191   ⟸   XM_021062532
- UniProtKB: A0A8D1MKJ5 (UniProtKB/TrEMBL),   A0A5G2QZA2 (UniProtKB/TrEMBL),   A0A4X1UK22 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000024313   ⟸   ENSSSCT00000025742
Ensembl Acc Id: ENSSSCP00000019221   ⟸   ENSSSCT00000024218
Ensembl Acc Id: ENSSSCP00000070221   ⟸   ENSSSCT00000073379


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000022347 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025067126 UniProtKB/TrEMBL
  ENSSSCG00030074589 UniProtKB/TrEMBL
  ENSSSCG00035007177 UniProtKB/TrEMBL
  ENSSSCG00040066161 UniProtKB/TrEMBL
  ENSSSCG00045020526 UniProtKB/TrEMBL
  ENSSSCG00050044287 UniProtKB/TrEMBL
  ENSSSCG00060027602 UniProtKB/TrEMBL
  ENSSSCG00065062415 UniProtKB/TrEMBL
  ENSSSCG00070017401 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000073379 ENTREZGENE
  ENSSSCT00000073379.2 UniProtKB/TrEMBL
  ENSSSCT00025092212.1 UniProtKB/TrEMBL
  ENSSSCT00030104713.1 UniProtKB/TrEMBL
  ENSSSCT00035008909.1 UniProtKB/TrEMBL
  ENSSSCT00035008914.1 UniProtKB/TrEMBL
  ENSSSCT00035008916.1 UniProtKB/TrEMBL
  ENSSSCT00040090365.1 UniProtKB/TrEMBL
  ENSSSCT00045035024.1 UniProtKB/TrEMBL
  ENSSSCT00050060290.1 UniProtKB/TrEMBL
  ENSSSCT00060037363.1 UniProtKB/TrEMBL
  ENSSSCT00065085623.1 UniProtKB/TrEMBL
  ENSSSCT00070034352.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2460.20 UniProtKB/TrEMBL
InterPro Wnt UniProtKB/TrEMBL
  Wnt_C UniProtKB/TrEMBL
  Wnt_CS UniProtKB/TrEMBL
KEGG Report ssc:100521912 UniProtKB/TrEMBL
NCBI Gene WNT11 ENTREZGENE
PANTHER PTHR12027 UniProtKB/TrEMBL
  PTHR12027:SF7 UniProtKB/TrEMBL
Pfam wnt UniProtKB/TrEMBL
PRINTS WNTPROTEIN UniProtKB/TrEMBL
PROSITE WNT1 UniProtKB/TrEMBL
SMART WNT1 UniProtKB/TrEMBL
UniProt A0A4X1UK22 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QZA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YKZ6_PIG UniProtKB/TrEMBL
  A0A8D1CKU3_PIG UniProtKB/TrEMBL
  A0A8D1MKJ5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94966 ENTREZGENE