MUC2 (mucin 2, oligomeric mucus/gel-forming) - Rat Genome Database

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Gene: MUC2 (mucin 2, oligomeric mucus/gel-forming) Sus scrofa
Analyze
Symbol: MUC2
Name: mucin 2, oligomeric mucus/gel-forming
RGD ID: 14184039
Description: ENCODES a protein that exhibits cupric ion binding (ortholog); cuprous ion binding (ortholog); extracellular matrix structural constituent (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to interleukin-1 (ortholog); cellular response to tumor necrosis factor (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); adenoma (ortholog); allergic conjunctivitis (ortholog); FOUND IN extracellular matrix (ortholog); inner mucus layer (ortholog); mucus layer (ortholog); INTERACTS WITH fumonisin B1
Type: protein-coding
RefSeq Status: MODEL
Previously known as: intestinal mucin-like protein; mucin-2; small intestinal mucin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2689,364 - 710,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12689,363 - 719,542 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140 - 7,521 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
fumonisin B1  (EXP)

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:25041765   PMID:26377360   PMID:30032202   PMID:30408134  


Genomics

Comparative Map Data
MUC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2689,364 - 710,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12689,363 - 719,542 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140 - 7,521 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MUC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,074,874 - 1,110,508 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,074,875 - 1,110,511 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,074,874 - 1,104,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,064,902 - 1,094,419 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,064,874 - 1,094,416NCBI
Cytogenetic Map11p15.5NCBI
HuRef11897,783 - 932,205 (+)NCBIHuRef
CHM1_1111,073,796 - 1,103,733 (+)NCBICHM1_1
T2T-CHM13v2.0111,144,674 - 1,182,053 (+)NCBIT2T-CHM13v2.0
Muc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,276,583 - 141,308,428 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7141,276,583 - 141,308,430 (+)EnsemblGRCm39 Ensembl
GRCm387141,690,340 - 141,754,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,690,340 - 141,754,693 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,930,517 - 148,940,598 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv377148,876,261 - 148,890,250 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,553,920 - 141,565,981 (+)NCBIMGSCv36mm8
Celera7141,484,086 - 141,510,531 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.1NCBI
Muc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81206,225,775 - 206,261,280 (+)NCBIGRCr8
mRatBN7.21196,799,494 - 196,831,740 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,799,517 - 196,831,756 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01214,663,929 - 214,693,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,664,537 - 214,693,043 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01221,581,822 - 221,611,451 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1194,430,946 - 194,458,668 (+)NCBICelera
Celera1194,458,772 - 194,461,359 (+)NCBICelera
Cytogenetic Map1q41NCBI
Muc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,108,826 - 11,135,697 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,108,826 - 11,135,697 (-)NCBIChiLan1.0ChiLan1.0
MUC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,487,647 - 3,523,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,698,364 - 2,735,182 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0111,106,716 - 1,144,489 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,143,625 - 1,180,798 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,143,625 - 1,169,741 (+)Ensemblpanpan1.1panPan2
MUC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11845,416,347 - 45,438,226 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01846,091,348 - 46,116,933 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11845,539,151 - 45,565,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01845,119,185 - 45,145,631 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,857,452 - 45,883,423 (+)NCBIUU_Cfam_GSD_1.0
Muc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947806,466 - 835,556 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493681660,499 - 91,628 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493681660,499 - 91,628 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MUC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11893,554 - 926,854 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603898,020,755 - 98,058,827 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Muc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476621,493,125 - 21,522,535 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MUC2
378 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
mesenchyme
nervous system
reproductive system
10 1 1 4 1 1

Sequence


Ensembl Acc Id: ENSSSCT00000068079   ⟹   ENSSSCP00000067835
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2689,364 - 701,911 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000086426   ⟹   ENSSSCP00000073903
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2689,364 - 710,330 (+)Ensembl
RefSeq Acc Id: XM_021082584   ⟹   XP_020938243
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12689,363 - 719,542 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020938243 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABV54142 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000067835.2
  ENSSSCP00000073903.2
RefSeq Acc Id: XP_020938243   ⟸   XM_021082584
- Sequence:
Ensembl Acc Id: ENSSSCP00000073903   ⟸   ENSSSCT00000086426
Ensembl Acc Id: ENSSSCP00000067835   ⟸   ENSSSCT00000068079
Protein Domains
VWFD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000040035 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000068079.2 UniProtKB/TrEMBL
  ENSSSCT00000086426.2 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro Mucin_vWF_Thrombospondin_sf UniProtKB/TrEMBL
  Ser_inhib-like_sf UniProtKB/TrEMBL
  TIL_dom UniProtKB/TrEMBL
  Unchr_dom_Cys-rich UniProtKB/TrEMBL
  VWF_dom UniProtKB/TrEMBL
  VWF_type-D UniProtKB/TrEMBL
  WxxW_domain UniProtKB/TrEMBL
NCBI Gene MUC2 ENTREZGENE
PANTHER EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED UniProtKB/TrEMBL
  MUCIN-2 UniProtKB/TrEMBL
Pfam Mucin2_WxxW UniProtKB/TrEMBL
  PF08742 UniProtKB/TrEMBL
  TIL UniProtKB/TrEMBL
  VWD UniProtKB/TrEMBL
PROSITE VWFD UniProtKB/TrEMBL
SMART SM00832 UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
  VWD UniProtKB/TrEMBL
Superfamily-SCOP FnI-like domain UniProtKB/TrEMBL
  SSF57567 UniProtKB/TrEMBL
UniProt A0A5G2QSD1_PIG UniProtKB/TrEMBL
  A0A5G2R9D7_PIG UniProtKB/TrEMBL
VGNC ID VGNC:111101 ENTREZGENE