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Gene: TBX4 (T-box transcription factor 4) Sus scrofa

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Symbol:

TBX4

Name:

T-box transcription factor 4

RGD ID:

14168816

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN angiogenesis (inferred); embryonic hindlimb morphogenesis (inferred); embryonic limb morphogenesis (inferred); ASSOCIATED WITH Amelia, Autosomal Recessive (ortholog); arthropathy (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

T-box 4; T-box 4 protein; T-box transcription factor TBX4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TBX4 (T-box transcription factor 4)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Tbx4 (T-box 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tbx4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tbx4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TBX4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TBX4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tbx4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TBX4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tbx4 (T-box transcription factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	36,802,354 - 36,834,327 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	36,803,355 - 36,830,321 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	38,224,618 - 38,257,155 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TBX4	Pig	arthropathy	susceptibility	ISO	RGD:1319185	9068941	Small Patella Syndrome, OMIM:147891;DNA:missense mutation, nonsense mutation:exon, exon:p.G248V, p.Q62X	RGD	PMID:15106123\|REF_RGD_ID:1601422

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TBX4	Pig	Amelia, Autosomal Recessive		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Autosomal recessive amelia	ClinVar	PMID:24033266\|PMID:25741868\|PMID:28492532\|PMID:31761294\|PMID:31965066
TBX4	Pig	genetic disease		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:28492532
TBX4	Pig	hydronephrosis		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Hydronephrosis	ClinVar	PMID:25741868\|PMID:31965066
TBX4	Pig	ischiocoxopodopatellar syndrome		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Congenital coxa vara, patella aplasia and tarsal synostosis \| ClinVar more ...	ClinVar	PMID:11303519\|PMID:15106123\|PMID:16199547\|PMID:23592887\|PMID:24033266\|PMID:25741868\|PMID:27587546\|PMID:28492532\|PMID:29120062\|PMID:29631995\|PMID:29650961\|PMID:30029678\|PMID:30578397\|PMID:31151956\|PMID:31727138\|PMID:31761294\|PMID:31965066\|PMID:32079640\|PMID:32581362\|PMID:32860008\|PMID:35852389\|PMID:36085161
TBX4	Pig	Joubert syndrome 1		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Familial aplasia of the vermis	ClinVar	PMID:28492532
TBX4	Pig	Lung Agenesis		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Primary pulmonary hypoplasia	ClinVar
TBX4	Pig	megacolon		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Megacolon	ClinVar	PMID:21681106
TBX4	Pig	primary pulmonary hypertension 1		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1	ClinVar	PMID:15106123\|PMID:16199547\|PMID:17576681\|PMID:23592887\|PMID:25741868\|PMID:27587546\|PMID:28492532\|PMID:29120062\|PMID:29631995\|PMID:29650961\|PMID:30029678\|PMID:30578397\|PMID:31151956\|PMID:31727138\|PMID:31761294\|PMID:31965066\|PMID:32079640\|PMID:32348326\|PMID:32581362\|PMID:32860008\|PMID:33066286\|PMID:33971972\|PMID:34557690\|PMID:36085161\|PMID:9536098
TBX4	Pig	Pulmonary Arterial Hypertension		ISO	RGD:1319185	8554872	ClinVar Annotator: match by term: Pulmonary arterial hypertension \| ClinVar Annotator: match by term: Pulmonary more ...	ClinVar	PMID:15106123\|PMID:16199547\|PMID:23592887\|PMID:25741868\|PMID:28492532\|PMID:29120062\|PMID:29631995\|PMID:29650961\|PMID:30029678\|PMID:30578397\|PMID:31151956\|PMID:31727138\|PMID:31761294\|PMID:31965066\|PMID:32079640\|PMID:32581362\|PMID:32860008\|PMID:33066286

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TBX4	Pig	Amelia, Autosomal Recessive		ISO	RGD:1319185	7240710		OMIM
TBX4	Pig	ischiocoxopodopatellar syndrome		ISO	RGD:1319185	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TBX4	Pig	angiogenesis	involved_in	IBA	MGI:102556\|PANTHER:PTN002601228	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	angiogenesis	acts_upstream_of_or_within	IEA	UniProtKB:P70325\|ensembl:ENSMUSP00000103682	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	cell fate specification	involved_in	IBA	FB:FBgn0261963\|MGI:102539\|MGI:1201683\|MGI:98493\|PANTHER:PTN000137774\|WB:WBGene00003106\|WB:WBGene00003376\|WB:WBGene00006543\|WB:WBGene00006554\|ZFIN:ZDB-GENE-001228-1\|ZFIN:ZDB-GENE-990726-27	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	embryonic hindlimb morphogenesis	involved_in	IEA	UniProtKB:P57082\|ensembl:ENSP00000495986	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	embryonic limb morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:P70325\|ensembl:ENSMUSP00000103682	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	embryonic lung development	involved_in	IEA	UniProtKB:P57082\|ensembl:ENSP00000495986	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	limb morphogenesis	involved_in	IEA	UniProtKB:P57082\|ensembl:ENSP00000495986	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	limb morphogenesis	acts_upstream_of_or_within	IEA	UniProtKB:P70325\|ensembl:ENSMUSP00000103682	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	lung development	acts_upstream_of_or_within	IEA	UniProtKB:P70325\|ensembl:ENSMUSP00000103682	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	morphogenesis of an epithelium	acts_upstream_of_or_within	IEA	UniProtKB:P70325\|ensembl:ENSMUSP00000103682	150520179		Ensembl	GO_REF:0000107
TBX4	Pig	positive regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR046360	150520179		InterPro	GO_REF:0000002
TBX4	Pig	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR001699\|InterPro:IPR008967\|InterPro:IPR018186\|InterPro:IPR036960	150520179		InterPro	GO_REF:0000002
TBX4	Pig	regulation of transcription by RNA polymerase II	involved_in	IBA	FB:FBgn0000179\|FB:FBgn0011723\|FB:FBgn0016660\|FB:FBgn0021767\|FB:FBgn0028789\|FB:FBgn0035954\|FB:FBgn0035956\|FB:FBgn0261963\|MGI:102539\|MGI:102541\|MGI:107404\|MGI:1201683\|MGI:1277234\|MGI:1352483\|MGI:1888496\|MGI:1888984\|MGI:1891158\|MGI:1923615\|MGI:98472\|MGI:98493\|MGI:98494\|MGI:98495\|PANTHER:PTN004251338\|RGD:735203\|UniProtKB:A0A8J1KRG6\|UniProtKB:O15119\|UniProtKB:O15178\|UniProtKB:O95936\|UniProtKB:Q13207\|UniProtKB:Q99593\|UniProtKB:Q9UL17\|UniProtKB:Q9Y458\|WB:WBGene00003106\|WB:WBGene00004750\|WB:WBGene00006554\|ZFIN:ZDB-GENE-991124-7	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	skeletal system morphogenesis	involved_in	IEA	UniProtKB:P57082\|ensembl:ENSP00000495986	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TBX4	Pig	chromatin	is_active_in	IBA	MGI:102539\|MGI:1201683\|MGI:98472\|PANTHER:PTN004251338\|UniProtKB:O15178\|ZFIN:ZDB-GENE-020416-5\|ZFIN:ZDB-GENE-980526-437\|ZFIN:ZDB-GENE-990615-5	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	nucleus	located_in	IEA	InterPro:IPR018186\|InterPro:IPR036960	150520179		InterPro	GO_REF:0000002
TBX4	Pig	nucleus	is_active_in	IBA	FB:FBgn0000179\|FB:FBgn0011723\|FB:FBgn0035954\|FB:FBgn0035956\|FB:FBgn0266083\|MGI:102539\|MGI:102541\|MGI:107404\|MGI:1201683\|MGI:1277234\|MGI:1888496\|MGI:1888984\|MGI:1923615\|MGI:98472\|MGI:98493\|MGI:98494\|MGI:98495\|PANTHER:PTN004251338\|UniProtKB:O15119\|UniProtKB:O15178\|UniProtKB:O93288\|UniProtKB:O95935\|UniProtKB:Q13207\|UniProtKB:Q16650\|UniProtKB:Q8IWI9\|UniProtKB:Q8UW76\|UniProtKB:Q99593\|UniProtKB:Q9PWE8\|UniProtKB:Q9Y458\|WB:WBGene00003106\|WB:WBGene00003376\|WB:WBGene00004750\|WB:WBGene00006543\|WB:WBGene00006545\|WB:WBGene00006546\|WB:WBGene00006556\|WB:WBGene00006557\|ZFIN:ZDB-GENE-001228-1\|ZFIN:ZDB-GENE-980526-437\|ZFIN:ZDB-GENE-990615-5\|ZFIN:ZDB-GENE-991124-7	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	nucleus	located_in	IEA	UniRule:UR000400702	150520179		UniProt	GO_REF:0000104
TBX4	Pig	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
TBX4	Pig	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TBX4	Pig	DNA binding	enables	IEA	UniRule:UR000400702	150520179		UniProt	GO_REF:0000104
TBX4	Pig	DNA binding	enables	IEA	UniProtKB-KW:KW-0238	150520179		UniProt	GO_REF:0000043
TBX4	Pig	DNA-binding transcription factor activity	enables	IEA	InterPro:IPR001699\|InterPro:IPR008967\|InterPro:IPR018186\|InterPro:IPR036960\|InterPro:IPR046360	150520179		InterPro	GO_REF:0000002
TBX4	Pig	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	FB:FBgn0011723\|FB:FBgn0028789\|FB:FBgn0035956\|FB:FBgn0261963\|MGI:102541\|MGI:1277234\|MGI:1352483\|MGI:1888496\|MGI:1888984\|MGI:1891158\|MGI:1923615\|MGI:98472\|MGI:98493\|PANTHER:PTN004251338\|UniProtKB:O15119\|UniProtKB:O15178\|UniProtKB:Q13207\|UniProtKB:Q99593\|UniProtKB:Q9UL17\|UniProtKB:Q9UMR3\|ZFIN:ZDB-GENE-001228-1	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	protein binding	enables	ISO	PR:Q8BX22	9068941	PMID:16380715	MGI	PMID:16380715
TBX4	Pig	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA	MGI:102539\|MGI:102541\|MGI:107404\|MGI:1277234\|MGI:1888496\|MGI:1891158\|MGI:1923615\|MGI:98472\|MGI:98494\|MGI:98495\|PANTHER:PTN004251338\|UniProtKB:O15119\|UniProtKB:O15178\|UniProtKB:Q13207\|UniProtKB:Q99593	150520179		GO_Central	GO_REF:0000033
TBX4	Pig	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IEA	InterPro:IPR001699	150520179		InterPro	GO_REF:0000002

PMID:22301074	PMID:30032202

TBX4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	36,802,354 - 36,834,327 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	36,803,355 - 36,830,321 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	38,224,618 - 38,257,155 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TBX4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	61,452,422 - 61,485,110 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	61,452,404 - 61,485,110 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	59,529,783 - 59,562,471 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	56,888,589 - 56,916,446 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	56,888,588 - 56,916,446	NCBI
Celera	17	58,634,841 - 58,662,701 (+)	NCBI		Celera
Cytogenetic Map	17	q23.2	NCBI
HuRef	17	54,900,265 - 54,928,130 (+)	NCBI		HuRef
CHM1_1	17	59,598,306 - 59,626,165 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	62,321,267 - 62,353,953 (+)	NCBI		T2T-CHM13v2.0

Tbx4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	85,777,193 - 85,806,923 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	85,777,248 - 85,806,923 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	85,886,367 - 85,916,097 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	85,886,422 - 85,916,097 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	85,703,565 - 85,729,599 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	85,706,258 - 85,730,940 (+)	NCBI		MGSCv36	mm8
Celera	11	95,517,399 - 95,543,455 (+)	NCBI		Celera
Cytogenetic Map	11	C	NCBI
cM Map	11	51.42	NCBI

Tbx4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	71,228,145 - 71,258,222 (+)	NCBI		GRCr8
mRatBN7.2	10	70,730,686 - 70,760,829 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	70,731,163 - 70,760,825 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	75,351,118 - 75,380,785 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	74,855,915 - 74,885,582 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	70,320,562 - 70,350,228 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	73,331,864 - 73,362,784 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	73,333,119 - 73,362,783 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	73,235,103 - 73,265,118 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	74,136,416 - 74,166,080 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	74,154,279 - 74,179,007 (+)	NCBI
Celera	10	69,654,749 - 69,684,469 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

Tbx4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	2,501,827 - 2,533,136 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	2,491,525 - 2,532,948 (+)	NCBI	ChiLan1.0	ChiLan1.0

TBX4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	77,651,294 - 77,684,008 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	82,462,735 - 82,495,443 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	55,554,549 - 55,587,253 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	60,677,518 - 60,706,206 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	60,677,518 - 60,705,413 (+)	Ensembl	panpan1.1		panPan2

TBX4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	35,163,346 - 35,197,726 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	35,166,353 - 35,191,932 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	34,395,807 - 34,421,394 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	35,972,610 - 36,007,370 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	35,977,705 - 36,003,297 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	34,758,715 - 34,784,294 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	35,044,477 - 35,070,057 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	35,132,002 - 35,157,583 (-)	NCBI		UU_Cfam_GSD_1.0

Tbx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	34,221,462 - 34,247,634 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	2,827,416 - 2,852,917 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	2,823,531 - 2,853,282 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TBX4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	32,677,878 - 32,715,169 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	32,683,921 - 32,711,674 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	3,430,924 - 3,463,642 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tbx4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624871	2,366,823 - 2,390,269 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624871	2,365,836 - 2,390,269 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in TBX4
965 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

circulatory system	ectoderm	mesenchyme	mesoderm	nervous system	reproductive system
2	6	3	3	6	1


RefSeq Transcripts	NM_001246249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP340220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HQ630072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000023325 ⟹ ENSSSCP00000027576

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	36,802,354 - 36,834,327 (-)	Ensembl

RefSeq Acc Id:

NM_001246249 ⟹ NP_001233178

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	36,803,355 - 36,830,321 (-)	NCBI

Sequence:

show sequence

ATGCTGCAGGATAAGGGCCTATCGGAGAGCGAGGAGGCCTTCCGGGCCTCGGGCTCCGCGCTCGGCGAGACCAGCGCAGCCAACGCCGCCAGCGTCCCCGAGCCCGCGCTGGCCGCGCCAGGCCTCGG
CGGAGCCCCGCTCGGCAGCCCCCCGGGCACTGGCGCCGACGTCGCCACCGCTGCCGCCGCTGAGCAGACCATCGAGAACATCAAGGTGGGCCTGCATGAGAAGGAGCTCTGGAAGAAGTTCCACGAGG
CGGGCACCGAGATGATCATCACCAAGGCGGGCAGGAGGATGTTCCCCAGCTACAAGGTCAAAGTCACAGGCATGAATCCCAAGACCAAGTACATCCTGCTGATCGACATTGTCCCCGCGGATGACCAC
CGCTACAAGTTCTGTGACAACAAATGGATGGTGGCAGGGAAGGCCGAGCCAGCCATGCCAGGAAGGCTCTACGTCCACCCAGATTCTCCTGCCACTGGGGCCCACTGGATGCGGCAGCTGGTCTCCTT
CCAGAAGCTGAAGCTGACGAACAACCACCTGGACCCCTTCGGCCATATCATCCTCAACTCCATGCACAAGTACCAGCCGCGGCTCCACATCGTGAAGGCAGATGAGAACAATGCTTTTGGTTCCAAAA
ACACAGCCTTCTGCACCCACGTGTTCCCAGAGACTTCTTTCATCTCCGTGACCTCCTACCAGAACCACAAGATCACGCAGCTGAAAATTGAGAACAACCCTTTCGCCAAGGGATTCCGGGGCAGTGAT
GACAGCGACCTGCGTGTGGCCCGGCTGCAGAGCAAAGAATATCCTGTGATCTCCAAAAGCATCATGCGGCAGAGGCTCGTCTCCACGCAGCTCTCGTCCAAGCCTGACGTCAGCCCCCTGCACGGGGC
TCACCAGGCGCTCCAGCACTACCAGTACGAGAACGGGGCTCACATGCAGTTCGCCGCAGCTGAGCCACAGGACCTTCCCCTCAACACCTTTCCCGCCCAGAGGGACTCCAGCCTCTTCTATCACTGCC
TGAAAAGACGAGACAGTGCCCGCCACCTGGACTTACCCTGCAAGCGATCCTATCTGGAAGCCCCCTCCACGGTGGCGGAGGATCATTATTTCCGCTCGCCCCCTCCCTACGACCAACAGATGCTGAGC
CCCTCCTACTGCAGCGAGGTGACCCCCCGCGACGCCTGCATGTACTCGGGTTCAGGGCCCGAGATCGCCGGGGTGTCCGGGGTGGACGACTTGCCCCCGCCCCCGCTGAGCTGTAACATGTGGACGTC
CGTGTCGCCGTACACGAGCTACGGCGTTCAGACCATGGAGACTGTGCCTTACCAGTCCTTCCCCACGCACTTCACCGCCACCACTATGATGCCCCGGCTGCCCACCATCTCGGCGCAGAGCTCGCAGC
CGCCGGGGAACGCGCACTTCAGCGTCTACAATCAGCTCTCCCAGTCTCAGGTCCGAGAGCGGGGGCCCAGCGCCTCCTTCCCGAGGGAGAGGGGCCTCCCCGCCGCCGTGTGCGAGAGGAAGCCGCCC
TCGCCGCACCTGAATGCTGCCAACGAGTTCCTCTACTCGCAGAGCTTCTCCCTGTCCCGGGAAGCCTCCCTACAGTACCATTCAGGCATGGGGACTGTGGAGAACTGGACCGACGGATGA

hide sequence


Protein RefSeqs	NP_001233178	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AEI00730	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000027576
	ENSSSCP00000027576.3
	ENSSSCP00015018432.1
	ENSSSCP00025022520.1
	ENSSSCP00030018939.1
	ENSSSCP00035026822.1
	ENSSSCP00040013998.1
	ENSSSCP00045006569.1
	ENSSSCP00050034968.1
	ENSSSCP00060045969.1
	ENSSSCP00065032753.1
	ENSSSCP00070005927.1

RefSeq Acc Id:

NP_001233178 ⟸ NM_001246249

- UniProtKB:

F8SIP7 (UniProtKB/TrEMBL), A0A4X1SUF9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLQDKGLSESEEAFRASGSALGETSAANAASVPEPALAAPGLGGAPLGSPPGTGADVATAAAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDH
RYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSD
DSDLRVARLQSKEYPVISKSIMRQRLVSTQLSSKPDVSPLHGAHQALQHYQYENGAHMQFAAAEPQDLPLNTFPAQRDSSLFYHCLKRRDSARHLDLPCKRSYLEAPSTVAEDHYFRSPPPYDQQMLS
PSYCSEVTPRDACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYGVQTMETVPYQSFPTHFTATTMMPRLPTISAQSSQPPGNAHFSVYNQLSQSQVRERGPSASFPRERGLPAAVCERKPP
SPHLNAANEFLYSQSFSLSREASLQYHSGMGTVENWTDG

hide sequence

Ensembl Acc Id:

ENSSSCP00000027576 ⟸ ENSSSCT00000023325

Protein Domains

T-box

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000022980	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015034110	UniProtKB/TrEMBL
	ENSSSCG00025038724	UniProtKB/TrEMBL
	ENSSSCG00030029932	UniProtKB/TrEMBL
	ENSSSCG00035049572	UniProtKB/TrEMBL
	ENSSSCG00040024920	UniProtKB/TrEMBL
	ENSSSCG00045005781	UniProtKB/TrEMBL
	ENSSSCG00050059776	UniProtKB/TrEMBL
	ENSSSCG00060076236	UniProtKB/TrEMBL
	ENSSSCG00065054896	UniProtKB/TrEMBL
	ENSSSCG00070003850	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000023325	ENTREZGENE
	ENSSSCT00000023325.4	UniProtKB/TrEMBL
	ENSSSCT00015046608.1	UniProtKB/TrEMBL
	ENSSSCT00025052839.1	UniProtKB/TrEMBL
	ENSSSCT00030041696.1	UniProtKB/TrEMBL
	ENSSSCT00035066116.1	UniProtKB/TrEMBL
	ENSSSCT00040033970.1	UniProtKB/TrEMBL
	ENSSSCT00045009624.1	UniProtKB/TrEMBL
	ENSSSCT00050081454.1	UniProtKB/TrEMBL
	ENSSSCT00060104826.1	UniProtKB/TrEMBL
	ENSSSCT00065075218.1	UniProtKB/TrEMBL
	ENSSSCT00070007247.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.820	UniProtKB/TrEMBL
InterPro	p53-like_TF_DNA-bd	UniProtKB/TrEMBL
	T-box_DNA-bd	UniProtKB/TrEMBL
	T-box_sf	UniProtKB/TrEMBL
	TF_T-box	UniProtKB/TrEMBL
	TF_T-box_CS	UniProtKB/TrEMBL
KEGG Report	ssc:100620126	UniProtKB/TrEMBL
NCBI Gene	TBX4	ENTREZGENE
PANTHER	PTHR11267	UniProtKB/TrEMBL
	T-BOX TRANSCRIPTION FACTOR TBX4	UniProtKB/TrEMBL
Pfam	T-box	UniProtKB/TrEMBL
PRINTS	TBOX	UniProtKB/TrEMBL
PROSITE	TBOX_1	UniProtKB/TrEMBL
	TBOX_2	UniProtKB/TrEMBL
	TBOX_3	UniProtKB/TrEMBL
SMART	TBOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49417	UniProtKB/TrEMBL
UniProt	A0A4X1SUF9	ENTREZGENE, UniProtKB/TrEMBL
	F8SIP7	ENTREZGENE, UniProtKB/TrEMBL
	I3LTX7_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:93803	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-06-11	TBX4	T-box transcription factor 4	TBX4	T-box 4	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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