Tbx4 (T-box transcription factor 4) - Rat Genome Database

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Gene: Tbx4 (T-box transcription factor 4) Heterocephalus glaber
Analyze
Symbol: Tbx4
Name: T-box transcription factor 4
RGD ID: 18901637
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN angiogenesis (ortholog); embryonic hindlimb morphogenesis (ortholog); embryonic limb morphogenesis (ortholog); ASSOCIATED WITH Amelia, Autosomal Recessive (ortholog); arthropathy (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-box 4; T-box transcription factor TBX4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248712,366,823 - 2,390,269 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248712,365,836 - 2,390,269 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tbx4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248712,366,823 - 2,390,269 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248712,365,836 - 2,390,269 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TBX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381761,452,422 - 61,485,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1761,452,404 - 61,485,110 (+)EnsemblGRCh38hg38GRCh38
GRCh371759,529,783 - 59,562,471 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361756,888,589 - 56,916,446 (+)NCBINCBI36Build 36hg18NCBI36
Build 341756,888,588 - 56,916,446NCBI
Celera1758,634,841 - 58,662,701 (+)NCBICelera
Cytogenetic Map17q23.2NCBI
HuRef1754,900,265 - 54,928,130 (+)NCBIHuRef
CHM1_11759,598,306 - 59,626,165 (+)NCBICHM1_1
T2T-CHM13v2.01762,321,267 - 62,353,953 (+)NCBIT2T-CHM13v2.0
Tbx4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,777,193 - 85,806,923 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,777,248 - 85,806,923 (+)EnsemblGRCm39 Ensembl
GRCm381185,886,367 - 85,916,097 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,886,422 - 85,916,097 (+)EnsemblGRCm38mm10GRCm38
MGSCv371185,703,565 - 85,729,599 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361185,706,258 - 85,730,940 (+)NCBIMGSCv36mm8
Celera1195,517,399 - 95,543,455 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.42NCBI
Tbx4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81071,228,145 - 71,258,222 (+)NCBIGRCr8
mRatBN7.21070,730,686 - 70,760,829 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1070,731,163 - 70,760,825 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1075,351,118 - 75,380,785 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01074,855,915 - 74,885,582 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01070,320,562 - 70,350,228 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01073,331,864 - 73,362,784 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1073,333,119 - 73,362,783 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01073,235,103 - 73,265,118 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41074,136,416 - 74,166,080 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11074,154,279 - 74,179,007 (+)NCBI
Celera1069,654,749 - 69,684,469 (+)NCBICelera
Cytogenetic Map10q26NCBI
Tbx4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554512,501,827 - 2,533,136 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554512,491,525 - 2,532,948 (+)NCBIChiLan1.0ChiLan1.0
TBX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21977,651,294 - 77,684,008 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11782,462,735 - 82,495,443 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01755,554,549 - 55,587,253 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11760,677,518 - 60,706,206 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1760,677,518 - 60,705,413 (+)Ensemblpanpan1.1panPan2
TBX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1935,163,346 - 35,197,726 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl935,166,353 - 35,191,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha934,395,807 - 34,421,394 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0935,972,610 - 36,007,370 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl935,977,705 - 36,003,297 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1934,758,715 - 34,784,294 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0935,044,477 - 35,070,057 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0935,132,002 - 35,157,583 (-)NCBIUU_Cfam_GSD_1.0
Tbx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560234,221,462 - 34,247,634 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364902,827,416 - 2,852,917 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364902,823,531 - 2,853,282 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,802,354 - 36,834,327 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,803,355 - 36,830,321 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21238,224,618 - 38,257,155 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11632,677,878 - 32,715,169 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1632,683,921 - 32,711,674 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660773,430,924 - 3,463,642 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000014447   ⟹   ENSHGLP00000014303
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248712,366,823 - 2,390,269 (-)Ensembl
RefSeq Acc Id: XM_004870379   ⟹   XP_004870436
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248712,365,836 - 2,390,269 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004870436 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB06435 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014303
Reference Protein Sequences
RefSeq Acc Id: XP_004870436   ⟸   XM_004870379
- UniProtKB: G5BAX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014303   ⟸   ENSHGLT00000014447


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010229 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014447 ENTREZGENE
Gene3D-CATH Transcription factor, T-box UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd_sf UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/TrEMBL
  T-box_sf UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/TrEMBL
NCBI Gene Tbx4 ENTREZGENE
PANTHER T-BOX PROTEIN-RELATED UniProtKB/TrEMBL
  T-BOX TRANSCRIPTION FACTOR TBX4 UniProtKB/TrEMBL
Pfam T-box UniProtKB/TrEMBL
PRINTS TBOX UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/TrEMBL
  TBOX_2 UniProtKB/TrEMBL
  TBOX_3 UniProtKB/TrEMBL
SMART TBOX UniProtKB/TrEMBL
Superfamily-SCOP p53-like transcription factors UniProtKB/TrEMBL
UniProt G5BAX4 ENTREZGENE, UniProtKB/TrEMBL