UNG (uracil DNA glycosylase) - Rat Genome Database

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Gene: UNG (uracil DNA glycosylase) Sus scrofa
Analyze
Symbol: UNG
Name: uracil DNA glycosylase
RGD ID: 14161097
Description: ENCODES a protein that exhibits uracil DNA N-glycosylase activity (ortholog); INVOLVED IN base-excision repair (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); Colorectal Neoplasms (ortholog); dysgammaglobulinemia (ortholog); FOUND IN mitochondrion (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: uracil-DNA glycosylase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,746,502 - 41,757,807 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,746,498 - 41,757,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,311,840 - 44,323,500 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UNGPigdysgammaglobulinemia  ISOUNG (Homo sapiens)9068941Hyper-IgM syndrome 5 and OMIM:608106RGDPMID:12958596 and REF_RGD_ID:1599705
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UNGPighereditary breast ovarian cancer syndrome  ISOUNG (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary breast ovarian cancer syndromeClinVarPMID:25741868
UNGPigimmunodeficiency with hyper IgM type 5  ISOUNG (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12958596 more ...
UNGPigX-linked hyper IgM syndrome  ISOUNG (Homo sapiens)8554872ClinVar Annotator: match by term: Hyperimmunoglobulin M syndromeClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UNGPigBloom syndrome  ISOUNG (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:2106500
UNGPigColorectal Neoplasms  ISOUNG (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15814641
UNGPighyper IgM syndrome  ISOUNG (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UNGPigimmunodeficiency with hyper IgM type 5  ISOUNG (Homo sapiens)7240710 OMIM 


Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UNGPigbase-excision repair  ISOUng (Rattus norvegicus)9068941 RGDPMID:12167490 and REF_RGD_ID:634481
UNGPigbase-excision repair involved_inIEAInterPro:IPR002043150520179 InterProGO_REF:0000002
UNGPigbase-excision repair involved_inIEAUniRule:UR000000669 and UniRule:UR000166147150520179 UniProtGO_REF:0000104
UNGPigbase-excision repair, AP site formation via deaminated base removal involved_inIEAUniProtKB:P13051 and ensembl:ENSP00000242576150520179 EnsemblGO_REF:0000107
UNGPigbase-excision repair, AP site formation via deaminated base removal involved_inIBAPANTHER:PTN000137400 more ...150520179 GO_CentralGO_REF:0000033
UNGPigDNA damage response involved_inIEAUniProtKB-KW:KW-0227150520179 UniProtGO_REF:0000043
UNGPigDNA repair involved_inIEAInterPro:IPR002043 and InterPro:IPR018085150520179 InterProGO_REF:0000002
UNGPigDNA repair involved_inIEAUniProtKB-KW:KW-0234150520179 UniProtGO_REF:0000043
UNGPigisotype switching acts_upstream_of_or_withinIEAUniProtKB:P97931 and ensembl:ENSMUSP00000031587150520179 EnsemblGO_REF:0000107
UNGPignegative regulation of apoptotic process  ISOUng (Rattus norvegicus)9068941 RGDPMID:15297456 and REF_RGD_ID:1599703
UNGPigsomatic hypermutation of immunoglobulin genes acts_upstream_of_or_withinIEAUniProtKB:P97931 and ensembl:ENSMUSP00000031587150520179 EnsemblGO_REF:0000107
UNGPigsomatic recombination of immunoglobulin gene segments acts_upstream_of_or_withinIEAUniProtKB:P97931 and ensembl:ENSMUSP00000031587150520179 EnsemblGO_REF:0000107
1 to 12 of 12 rows

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UNGPigmitochondrion located_inIEAUniProtKB:E5KTA5 more ...150520179 EnsemblGO_REF:0000107
UNGPigmitochondrion is_active_inIBAMGI:109352 more ...150520179 GO_CentralGO_REF:0000033
UNGPigmitochondrion located_inIEAUniProtKB-SubCell:SL-0173150520179 UniProtGO_REF:0000044
UNGPigmitochondrion located_inIEAUniRule:UR000166147150520179 UniProtGO_REF:0000104
UNGPigmitochondrion located_inIEAUniProtKB-KW:KW-0496150520179 UniProtGO_REF:0000043
UNGPignucleoplasm located_inIEAUniProtKB:E5KTA5 more ...150520179 EnsemblGO_REF:0000107
UNGPignucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
UNGPignucleus is_active_inIBAMGI:109352 more ...150520179 GO_CentralGO_REF:0000033
UNGPignucleus located_inIEAUniRule:UR000166147150520179 UniProtGO_REF:0000104
UNGPignucleus located_inIEAUniProtKB:P97931 and ensembl:ENSMUSP00000031587150520179 EnsemblGO_REF:0000107
UNGPignucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
1 to 11 of 11 rows

Molecular Function
1 to 13 of 13 rows

  
1 to 13 of 13 rows

PMID:14681463   PMID:22301074   PMID:30032202  



UNG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,746,502 - 41,757,807 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,746,498 - 41,757,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,311,840 - 44,323,500 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UNG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,097,597 - 109,110,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12109,097,597 - 109,126,725 (+)EnsemblGRCh38hg38GRCh38
GRCh3712109,535,402 - 109,548,797 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,019,798 - 108,033,181 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412107,998,134 - 108,011,518NCBI
Celera12109,159,338 - 109,172,962 (+)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12106,553,817 - 106,567,575 (+)NCBIHuRef
CHM1_112109,503,049 - 109,516,448 (+)NCBICHM1_1
T2T-CHM13v2.012109,072,409 - 109,086,041 (+)NCBIT2T-CHM13v2.0
Ung
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,268,427 - 114,277,382 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,268,447 - 114,277,384 (+)EnsemblGRCm39 Ensembl
GRCm385114,130,366 - 114,139,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,130,386 - 114,139,323 (+)EnsemblGRCm38mm10GRCm38
MGSCv375114,580,444 - 114,589,330 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,392,199 - 114,418,049 (+)NCBIMGSCv36mm8
Celera5111,232,303 - 111,241,182 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.97NCBI
Ung
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,145,838 - 48,154,789 (-)NCBIGRCr8
mRatBN7.21242,485,276 - 42,494,217 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,485,276 - 42,494,206 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1243,652,469 - 43,660,684 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,266,059 - 44,274,274 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,326,576 - 43,334,791 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,246,593 - 48,255,547 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,246,569 - 48,254,822 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,028,792 - 50,037,127 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,520,629 - 43,528,873 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,384,016 - 43,392,261 (-)NCBI
Celera1244,089,808 - 44,098,015 (-)NCBICelera
Cytogenetic Map12q16NCBI
Ung
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,266,989 - 10,282,196 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,266,989 - 10,282,196 (+)NCBIChiLan1.0ChiLan1.0
UNG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210117,163,347 - 117,176,365 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112117,159,745 - 117,172,766 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,674,073 - 106,687,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112110,067,882 - 110,080,891 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,067,879 - 110,080,891 (+)Ensemblpanpan1.1panPan2
UNG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,900,354 - 17,911,126 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,901,357 - 17,911,288 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,889,919 - 17,901,192 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02618,244,407 - 18,255,900 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,242,974 - 18,255,885 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,099,207 - 18,110,426 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,235,026 - 18,246,514 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,253,824 - 18,265,113 (-)NCBIUU_Cfam_GSD_1.0
Ung
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,553,145 - 144,565,155 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769910,838 - 922,726 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936769911,296 - 922,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111104,302,507 - 104,325,160 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037140,779,094 - 140,801,492 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ung
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,261,623 - 12,274,859 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,261,546 - 12,275,229 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in UNG
255 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3



Ensembl Acc Id: ENSSSCT00000010890   ⟹   ENSSSCP00000010605
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1441,746,501 - 41,757,862 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000063148   ⟹   ENSSSCP00000051637
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1441,746,502 - 41,757,807 (-)Ensembl
RefSeq Acc Id: XM_003132925   ⟹   XP_003132973
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11441,746,498 - 41,757,841 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003132973   ⟸   XM_003132925
- UniProtKB: A0A4X1STA4 (UniProtKB/TrEMBL),   A0A287B576 (UniProtKB/TrEMBL),   A0A8D0NS25 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000010605   ⟸   ENSSSCT00000010890
Ensembl Acc Id: ENSSSCP00000051637   ⟸   ENSSSCT00000063148
Uracil-DNA glycosylase-like



1 to 40 of 53 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000009938 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015043503 UniProtKB/TrEMBL
  ENSSSCG00025032568 UniProtKB/TrEMBL
  ENSSSCG00030060415 UniProtKB/TrEMBL
  ENSSSCG00035070156 UniProtKB/TrEMBL
  ENSSSCG00040004216 UniProtKB/TrEMBL
  ENSSSCG00045016340 UniProtKB/TrEMBL
  ENSSSCG00050066270 UniProtKB/TrEMBL
  ENSSSCG00055025240 UniProtKB/TrEMBL
  ENSSSCG00060077307 UniProtKB/TrEMBL
  ENSSSCG00065057972 UniProtKB/TrEMBL
  ENSSSCG00070003544 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000063148 ENTREZGENE
  ENSSSCT00000063148.3 UniProtKB/TrEMBL
  ENSSSCT00015057907.1 UniProtKB/TrEMBL
  ENSSSCT00025044281.1 UniProtKB/TrEMBL
  ENSSSCT00030084345.1 UniProtKB/TrEMBL
  ENSSSCT00035094759.1 UniProtKB/TrEMBL
  ENSSSCT00035094770.1 UniProtKB/TrEMBL
  ENSSSCT00040005471.1 UniProtKB/TrEMBL
  ENSSSCT00040005480.1 UniProtKB/TrEMBL
  ENSSSCT00045027797.1 UniProtKB/TrEMBL
  ENSSSCT00045027878.1 UniProtKB/TrEMBL
  ENSSSCT00050090271.1 UniProtKB/TrEMBL
  ENSSSCT00050090278.1 UniProtKB/TrEMBL
  ENSSSCT00055049861.1 UniProtKB/TrEMBL
  ENSSSCT00055049940.1 UniProtKB/TrEMBL
  ENSSSCT00060106354.1 UniProtKB/TrEMBL
  ENSSSCT00065079308.1 UniProtKB/TrEMBL
  ENSSSCT00065079313.1 UniProtKB/TrEMBL
  ENSSSCT00070006666.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.470.10 UniProtKB/TrEMBL
InterPro UDG_fam1 UniProtKB/TrEMBL
  Ura-DNA_Glyclase_AS UniProtKB/TrEMBL
  Uracil-DNA_glycosylase-like UniProtKB/TrEMBL
  Uracil-DNA_glycosylase-like_sf UniProtKB/TrEMBL
KEGG Report ssc:100519979 UniProtKB/TrEMBL
NCBI Gene UNG ENTREZGENE
PANTHER PTHR11264 UniProtKB/TrEMBL
  URACIL-DNA GLYCOSYLASE UniProtKB/TrEMBL
1 to 40 of 53 rows