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Gene: CYP27A1 (cytochrome P450 family 27 subfamily A member 1) Sus scrofa

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Symbol:

CYP27A1

Name:

cytochrome P450 family 27 subfamily A member 1

RGD ID:

14029165

Description:

ENCODES a protein that exhibits cholesterol 26-hydroxylase activity (ortholog); Hsp70 protein binding (ortholog); vitamin D 25-hydroxylase activity (ortholog); INVOLVED IN bile acid metabolic process (ortholog); cholesterol metabolic process (ortholog); vitamin D3 biosynthetic process (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; bile acid signaling pathway; cerebrotendinous xanthomatosis pathway; ASSOCIATED WITH atherosclerosis (ortholog); autism spectrum disorder (ortholog); Breast Cancer, Familial (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cytochrome P450, family 27, subfamily A, polypeptide 1; sterol 26-hydroxylase, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	120,809,959 - 120,852,192 (+)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	15	120,809,886 - 120,852,196 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	133,798,107 - 133,831,191 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atherosclerosis (ISO)

autism spectrum disorder (ISO)

Breast Cancer, Familial (ISO)

cerebrotendinous xanthomatosis (ISO)

cholestasis (ISO)

clear cell renal cell carcinoma (ISO)

coronary artery disease (ISO)

dystonia (ISO)

epilepsy (ISO)

extrahepatic cholestasis (ISO)

Gait Ataxia (ISO)

Gliosis (ISO)

hypothyroidism (ISO)

intellectual disability (ISO)

leukodystrophy (ISO)

liver cirrhosis (ISO)

Metabolic Bone Diseases (ISO)

metabolic dysfunction-associated steatohepatitis (ISO)

musculoskeletal system disease (ISO)

ovarian serous cystadenocarcinoma (ISO)

restless legs syndrome (ISO)

sarcoma (ISO)

stomach cancer (ISO)

urinary bladder cancer (ISO)

uterine corpus endometrial carcinoma (ISO)

Vision Disorders (ISO)

xanthomatosis (ISO)

Zellweger syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bile acid biosynthetic process (IEA)

bile acid metabolic process (ISO)

calcitriol biosynthetic process from calciol (IBA,IEA)

cholesterol catabolic process (IEA)

cholesterol metabolic process (IBA,ISO)

lipid metabolic process (IEA)

positive regulation of smoothened signaling pathway (IEA)

steroid metabolic process (IEA)

vitamin D3 biosynthetic process (ISO)

Cellular Component

mitochondrial inner membrane (IEA)

mitochondrion (IBA,ISO)

Molecular Function

cholestanetetraol 26-dehydrogenase activity (IEA)

cholesterol 26-hydroxylase activity (IBA,IEA,ISO)

heme binding (IEA)

Hsp70 protein binding (ISO)

iron ion binding (IEA)

monooxygenase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen (IEA)

vitamin D 25-hydroxylase activity (IBA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

bile acid biosynthetic pathway (ISO)

bile acid signaling pathway (ISO)

cerebrotendinous xanthomatosis pathway (ISO)

congenital bile acid synthesis defect pathway (ISO)

familial hypercholanemia pathway (ISO)

reverse cholesterol transport pathway (ISO)

Zellweger syndrome pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CYP27A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	120,809,959 - 120,852,192 (+)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	15	120,809,886 - 120,852,196 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	133,798,107 - 133,831,191 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CYP27A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	218,782,147 - 218,815,293 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	218,781,688 - 218,825,335 (+)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	2	219,646,870 - 219,680,016 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	219,354,949 - 219,388,259 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	219,472,209 - 219,505,520	NCBI
Celera	2	213,414,219 - 213,447,784 (+)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	211,499,575 - 211,533,141 (+)	NCBI		HuRef
CHM1_1	2	219,653,385 - 219,686,914 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	219,268,705 - 219,301,851 (+)	NCBI		T2T-CHM13v2.0

Cyp27a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	74,752,311 - 74,777,056 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	74,752,314 - 74,777,056 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	74,713,148 - 74,737,897 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	74,713,574 - 74,737,892 (+)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	1	74,760,148 - 74,784,464 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	74,646,781 - 74,671,097 (+)	NCBI		MGSCv36	mm8
Celera	1	75,268,638 - 75,292,903 (+)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	38.54	NCBI

Cyp27a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	83,712,402 - 83,743,222 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	83,713,293 - 83,743,215 (+)	Ensembl				GRCr8
mRatBN7.2	9	76,264,655 - 76,294,551 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,264,860 - 76,294,551 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	84,709,826 - 84,739,736 (+)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	89,838,774 - 89,868,679 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,224,941 - 88,254,850 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	9	87,364,125 - 87,393,859 (+)	NCBI
Lyon_Normotensive	9	83,184,432 - 83,214,167 (+)	NCBI
Lyon_Hypertensive	9	83,326,687 - 83,356,378 (+)	NCBI
F344_StmMcwi	9	85,287,283 - 85,316,977 (+)	NCBI
Rnor_6.0	9	81,968,285 - 81,998,213 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	81,968,332 - 81,998,169 (+)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	9	81,730,705 - 81,760,595 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	74,039,204 - 74,068,648 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	73,837,312 - 73,867,002 (+)	NCBI		Celera
RGSC_v3.1	9	74,186,068 - 74,215,629 (+)	NCBI
Cytogenetic Map	9	q33	NCBI

LOC102004889
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	14,601,444 - 14,647,366 (-)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955453	14,601,495 - 14,647,383 (-)	NCBI	ChiLan1.0	ChiLan1.0

CYP27A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	121,414,455 - 121,449,699 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	121,430,782 - 121,464,669 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	106,042,235 - 106,076,840 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	224,637,238 - 224,671,474 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	224,637,238 - 224,671,474 (+)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

CYP27A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	25,366,475 - 25,401,978 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	25,366,472 - 25,401,509 (+)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	26,186,269 - 26,221,708 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	25,381,673 - 25,417,125 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	25,382,000 - 25,602,692 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	25,286,426 - 25,321,814 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	25,221,115 - 25,256,548 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	25,241,871 - 25,277,345 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cyp27a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	7	180,753,433 - 180,791,214 (+)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024405303	174,870,819 - 174,907,409 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	1,213,573 - 1,250,589 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936569	1,213,700 - 1,250,181 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYP27A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	10	106,268,418 - 106,304,003 (+)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666040	94,685,776 - 94,722,151 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	10	104,682,437 - 104,723,781 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	104,682,673 - 104,726,687 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

LOC101700018
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624823	6,199,807 - 6,258,273 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624823	6,200,047 - 6,258,001 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl	25	28,719,839 - 28,779,162 (+)	Ensembl

LOC116899511
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	148,129,007 - 148,157,627 (+)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

Variants

Variants in CYP27A1
1525 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001243304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_084997925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_084997927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_084997928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_084997929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_084997930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK232936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK400072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU914509	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EF625352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01082461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JBREVY020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000017640 ⟹ ENSSSCP00000017162

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	120,812,385 - 120,852,191 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000028116 ⟹ ENSSSCP00000020985

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	15	120,809,959 - 120,852,192 (+)	Ensembl

RefSeq Acc Id:

NM_001243304 ⟹ NP_001230233

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	15	120,809,886 - 120,852,196 (+)	NCBI

Sequence:

show sequence

GAATCAGGTGACCCTGGACACAGGGCTGTTTTGTTGTTGCTGTTGTTTGTTTTACTTTTTTGTT
TGGGGGATTTTTTTTTTTTTTTTGCTCTTTCCTCGCTCAGCGCTCAGAGTCCGGGATCAACCCC
TGGGGCTCTTCGGAAAAGCCAGCAGCCAGTTTAATCTCTCCGGGCTGAGGCGTTGCGGCTTTGG
GGTGACGAGCCCGCTGAGCGTGAGGGCTGGACTCACTGGGTGAGGCCTCCAGGTCTTGGAAGCC
TCCCGGGCTACACTCCTGCCTGGAGTTCAGACCAAGCGAACTTCAAGTTCTCCACGAGAGTTCG
CCAAAGTGAAAGGTGGGGAGTCGCGGGAGAGGCGGCCATCGTCGGAGCTCTGTGGGTCCCCCTA
AGTGCCCCTGTGCATCTTCTGCCTTGGCGTTGTCCGGCCCCTTCCCGAGCCTGGAGGCTGACAG
TTGGAAAAGGGGGCTTCTGTGAGTTGGTTAAGTCCCGTTTGGAGAGACTGAAGACCGCGATGAA
ACCGGAGCAGTAAGGGGCCTGGCCAACCTTCGCCGGCCCACCCTGGGCTACCGGGGCCCTTGAA
CCCGCCCTTCCTGATTCGCCTTTGGGCGCGCTCGAGGCAGTCTGCACTCCAGATCTGAAGGTGC
CGCAGGACAAGCCATGAATAGCATGGGTGCGCTGGGTGGCGCGAGGCTGCGGTGGGCGCTGCTG
GGGACGCGAGTGCCCTTCCCTGTTCTGGGCTCACAGGGGGCCAGAGCCAAGGCCGCGATCCCCA
CCGCACTCCCGGCGGCCCAGACAGCGGAGGCTCCCGGAACCGGGCCTGGCGATCGGAGGCTGCG
GAGCTTGAAGGAGCTTTCCGGGCCAGGGCGGCTGCGCCTCTTATTCCAACTGTTAGCACAAGGC
TACGTTCTGCACTTACACCAGCTCCAGGTGCTGAACAAGGCCAAGTATGGTCCAATGTGGATAA
ACTATATAGGGCCTCAGATCCATGTGAACGTGGCCAGTGCCCCACTCCTGGAGCAAGTGATGCG
CCAAGAGGGCAAGTACCCAGTACGGAACGACATGGACCTGTGGAAGGAGCACCGGGACCTACAG
GGCCTGACCTATGGGCCCTTCACCACGGAAGGAGAGTCATGGTACCGGCTGCGCCAGGCTCTGA
ACCAGCGGATGCTGAAGCCAGCTGACGCTGCGCTCTACACCAATGCTCTGAATGAGGTGGTCGA
TGACTTCATGGTGCGACTGAACCAGCTTCGGGCAGAAAGCACCTTGGGGGACCACGTGCCCGAC
ATAGCTCACCAATTCTACTTCTTCGCCTTGGAAGCTATTTGCTACATCCTGTTTGAGAAACGCA
TTGGCTGCCTGGAGCGCTCCATCCCCCAGGACACCAAAGCCTTCGTCAGATCTGTCGGGTTCAT
GTTCCAGAACTCACTCTACGCCACCTTCCTCCCCAAGTGGACGCGTCCCCTGCTGCCCTACTGG
AGGCGATACCTGGATGGCTGGAATACCATCTTCTCTTTTGGGAAGAAGCTGATTGATCAGAAAC
TGGAGGAGATAGAGGCCCAACTGCAGGCGGGGGGCCCAGAGGAGCCCCGGATATCTGGTTACCT
GCACTTTCTGCTGACCAGCGGACAGCTCAGTCCTCGTGAGGCTGAGGGCAGCTTGCCGGAGCTG
CTCATGGCTGGAGTAGACACGACATCCAACACGCTGACATGGGCCCTGTACCATCTTTCAAAGA
ACCCAGAGATCCAGGCAGCCTTGCATGAGGAGGTGGTGGGCATGGTGCCCGCTGGGCGGGTGCC
GCAGTACAAGGACTTGGCCCACATGCCTCTGCTCAAAGCTGTGCTTAAGGAGACCCTGCGCCTC
TACCCTGTGGTGCCTGTGAACTCCAGGGTCATCACAGACAAGGAAATCGAAGTTGGTGGCTTCC
TCTTTCCCAAGAACACACAGTTTGTCTTGTGCCATTATGTGGTGTCCCGGGACCCCAGCATCTT
CCCTGAGCCTGACCGCTTCCAGCCCCAGCGCTGGCTGAGGAAGAACCAGACGGATGCTCTCAAG
GGCCAGCACCCATTTGGCTCCGTGCCCTTTGGCTACGGGGTCCGGGGTTGCCTGGGCCGCAGGA
TTGCAGAGCTGGAGATGCAGCTGCTGCTGACAAGGCTGATCCAGCAGTATGAGGTGACTCTGGC
CCCTGAGACGGGGGAAGTGACGAGTGTGGCTCGCATCGTTCTGGTTCCCAATAAGAAGGTGGGC
CTGCGTTTCCTGCAGAGACAGGGATGAGCTGGACCTCTGCCCTCCTGGGGCAGCCTCCTCTCCT
CCCTTGCTCCCTGGCACACAAGGCGGGAGAAAAAGGAGCTGCCAGGTGACAGAGGTTGGAGATG
CTCCGTGCCTCCCTGTAGAACCCTGAGCTTTTGCTGCTTTTATTATTTTGAACATCTCCCTCTC
AGATAAAAGGCCGCCTCCATGTCACACTGCTAACCTTGGGGACTATATGCAATAAAAGGGTTTT
TACTGATAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001230233	(Get FASTA)	NCBI Sequence Viewer
	XP_084854051	(Get FASTA)	NCBI Sequence Viewer
	XP_084854053	(Get FASTA)	NCBI Sequence Viewer
	XP_084854054	(Get FASTA)	NCBI Sequence Viewer
	XP_084854055	(Get FASTA)	NCBI Sequence Viewer
	XP_084854056	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABS58492	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017162.3
	ENSSSCP00000020985
	ENSSSCP00000020985.3

RefSeq Acc Id:

NP_001230233 ⟸ NM_001243304

- UniProtKB:

I3LAB7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNSMGALGGARLRWALLGTRVPFPVLGSQGARAKAAIPTALPAAQTAEAPGTGPGDRRLRSLKE
LSGPGRLRLLFQLLAQGYVLHLHQLQVLNKAKYGPMWINYIGPQIHVNVASAPLLEQVMRQEGK
YPVRNDMDLWKEHRDLQGLTYGPFTTEGESWYRLRQALNQRMLKPADAALYTNALNEVVDDFMV
RLNQLRAESTLGDHVPDIAHQFYFFALEAICYILFEKRIGCLERSIPQDTKAFVRSVGFMFQNS
LYATFLPKWTRPLLPYWRRYLDGWNTIFSFGKKLIDQKLEEIEAQLQAGGPEEPRISGYLHFLL
TSGQLSPREAEGSLPELLMAGVDTTSNTLTWALYHLSKNPEIQAALHEEVVGMVPAGRVPQYKD
LAHMPLLKAVLKETLRLYPVVPVNSRVITDKEIEVGGFLFPKNTQFVLCHYVVSRDPSIFPEPD
RFQPQRWLRKNQTDALKGQHPFGSVPFGYGVRGCLGRRIAELEMQLLLTRLIQQYEVTLAPETG
EVTSVARIVLVPNKKVGLRFLQRQG

hide sequence

Ensembl Acc Id:

ENSSSCP00000017162 ⟸ ENSSSCT00000017640

Ensembl Acc Id:

ENSSSCP00000020985 ⟸ ENSSSCT00000028116

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016199	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000017640.5	UniProtKB/TrEMBL
	ENSSSCT00000028116	ENTREZGENE
	ENSSSCT00000028116.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	CYP11_CYP27_families	UniProtKB/TrEMBL
	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
NCBI Gene	CYP27A1	ENTREZGENE
PANTHER	CYTOCHROME P450 FAMILY 27 SUBFAMILY A MEMBER 1	UniProtKB/TrEMBL
	PTHR24279	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450I	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	A7KZR6_PIG	UniProtKB/TrEMBL
	F1SRX1_PIG	UniProtKB/TrEMBL
	I3LAB7	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A8D1PCN5	UniProtKB/TrEMBL
VGNC ID	VGNC:103372	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-12-21	CYP27A1	cytochrome P450 family 27 subfamily A member 1	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB