ARHGAP6 (Rho GTPase activating protein 6) - Rat Genome Database

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Gene: ARHGAP6 (Rho GTPase activating protein 6) Homo sapiens
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Symbol: ARHGAP6
Name: Rho GTPase activating protein 6
RGD ID: 1349829
HGNC Page HGNC:676
Description: Enables phospholipase activator activity and phospholipase binding activity. Involved in negative regulation of focal adhesion assembly; negative regulation of stress fiber assembly; and positive regulation of phospholipase C/protein kinase C signal transduction. Located in cytosol and mitotic spindle.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: rho GTPase-activating protein 6; rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1; RHOGAP6; RHOGAPX-1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,137,544 - 11,665,920 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,117,651 - 11,665,920 (-)EnsemblGRCh38hg38GRCh38
GRCh37X11,155,664 - 11,684,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X11,065,584 - 11,593,742 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X10,915,323 - 11,443,478NCBI
CeleraX15,283,114 - 15,812,107 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBIHuRef
CHM1_1X11,186,095 - 11,714,183 (-)NCBICHM1_1
T2T-CHM13v2.0X10,720,022 - 11,248,464 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
ARHGAP6Humanamelogenesis imperfecta  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfectaClinVar 
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:10669095 more ...
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:25741868
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:11922868 and PMID:7599636
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:15111628
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVar 
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: AMELX-related conditionClinVarPMID:28492532
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:1916828 more ...
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:1967204 and PMID:3169793
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta more ...ClinVarPMID:23251683
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:11922868 and PMID:1483698
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:11201048 and PMID:11922868
ARHGAP6Humanamelogenesis imperfecta type 1E  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfecta type 1EClinVarPMID:11839357 and PMID:11922868
ARHGAP6Humanamenorrhea  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Primary amenorrheaClinVarPMID:21681106
ARHGAP6Humanautistic disorder  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
ARHGAP6Humangenetic disease  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
ARHGAP6Humanintellectual disability  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868
ARHGAP6Humanlinear skin defects with multiple congenital anomalies 1  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: HCCS-related conditionClinVarPMID:18414213 and PMID:28492532
ARHGAP6HumanNeurodevelopmental Disorders  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
ARHGAP6Humannon-syndromic X-linked intellectual disability 104  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: INTELLECTUAL DEVELOPMENTAL DISORDER and X-LINKED 104ClinVar 
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Original Reference(s)
ARHGAP6HumanFamilial Prostate Cancer  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:29892016
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Original Reference(s)
ARHGAP6Humanmicrophthalmia  ISSArhgap6 (Mus musculus)13592920OMIM:206900 more ...MouseDO 

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Original Reference(s)
ARHGAP6Human1,2-dichloroethane affects expressionISOArhgap6 (Mus musculus)6480464ethylene dichloride affects the expression of ARHGAP6 mRNACTDPMID:28960355
ARHGAP6Human1,2-dimethylhydrazine decreases expressionISOArhgap6 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of ARHGAP6 mRNACTDPMID:22206623
ARHGAP6Human17beta-estradiol decreases expressionISOArhgap6 (Rattus norvegicus)6480464Estradiol results in decreased expression of ARHGAP6 mRNACTDPMID:32145629
ARHGAP6Human17beta-estradiol decreases expressionISOArhgap6 (Mus musculus)6480464Estradiol results in decreased expression of ARHGAP6 mRNACTDPMID:39298647
ARHGAP6Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISOArhgap6 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of ARHGAP6 mRNACTDPMID:19933214
ARHGAP6Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISOArhgap6 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ARHGAP6 mRNACTDPMID:21570461
ARHGAP6Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOArhgap6 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of ARHGAP6 mRNACTDPMID:18172886
ARHGAP6Human3,3',5,5'-tetrabromobisphenol A increases expressionISOArhgap6 (Mus musculus)6480464tetrabromobisphenol A results in increased expression of ARHGAP6 mRNACTDPMID:25172293
ARHGAP6Human4,4'-sulfonyldiphenol increases expressionISOArhgap6 (Mus musculus)6480464bisphenol S results in increased expression of ARHGAP6 mRNACTDPMID:30951980
ARHGAP6Human4,4'-sulfonyldiphenol decreases expressionISOArhgap6 (Mus musculus)6480464bisphenol S results in decreased expression of ARHGAP6 mRNACTDPMID:39298647
ARHGAP6Human7,12-dimethyltetraphene decreases expressionISOArhgap6 (Mus musculus)64804649 more ...CTDPMID:32553695
ARHGAP6Humanaflatoxin B1 decreases methylationEXP 6480464Aflatoxin B1 results in decreased methylation of ARHGAP6 geneCTDPMID:27153756
ARHGAP6Humanaflatoxin B1 decreases expressionEXP 6480464Aflatoxin B1 results in decreased expression of ARHGAP6 mRNACTDPMID:32234424
ARHGAP6HumanAflatoxin B2 alpha decreases methylationEXP 6480464aflatoxin B2 results in decreased methylation of ARHGAP6 intronCTDPMID:30157460
ARHGAP6Humanaldehydo-D-glucose increases expressionISOArhgap6 (Mus musculus)6480464Glucose results in increased expression of ARHGAP6 mRNACTDPMID:31525975
ARHGAP6Humanall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of ARHGAP6 mRNACTDPMID:21934132 and PMID:23724009
ARHGAP6Humanaristolochic acid A decreases expressionEXP 6480464aristolochic acid I results in decreased expression of ARHGAP6 mRNACTDPMID:33212167
ARHGAP6Humanbenzo[a]pyrene decreases expressionISOArhgap6 (Mus musculus)6480464Benzo(a)pyrene metabolite results in decreased expression of ARHGAP6 mRNA and Benzo(a)pyrene results in decreased expression of ARHGAP6 mRNACTDPMID:19770486 and PMID:32553695
ARHGAP6Humanbenzo[a]pyrene decreases expressionEXP 6480464Benzo(a)pyrene results in decreased expression of ARHGAP6 mRNACTDPMID:32234424
ARHGAP6Humanbenzo[a]pyrene affects methylationEXP 6480464Benzo(a)pyrene affects the methylation of ARHGAP6 exon and Benzo(a)pyrene affects the methylation of ARHGAP6 promoterCTDPMID:27901495

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Biological Process
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Object Symbol
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Term
Qualifier
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Original Reference(s)
ARHGAP6Humanactin filament organization involved_inIBAMGI:1196332 and PANTHER:PTN000290807150520179 GO_CentralGO_REF:0000033
ARHGAP6Humanactin filament organization acts_upstream_of_or_withinIEAUniProtKB:O54834 and ensembl:ENSMUSP00000033721150520179 EnsemblGO_REF:0000107
ARHGAP6Humanactin filament polymerization involved_inNAS 150520179 PMID:10699171UniProtPMID:10699171
ARHGAP6Humanfocal adhesion assembly involved_inIBAMGI:1196332 and PANTHER:PTN000290807150520179 GO_CentralGO_REF:0000033
ARHGAP6Humanfocal adhesion assembly acts_upstream_of_or_withinIEAUniProtKB:O54834 and ensembl:ENSMUSP00000033721150520179 EnsemblGO_REF:0000107
ARHGAP6Humannegative regulation of focal adhesion assembly involved_inIMP 150520179 PMID:10699171BHF-UCLPMID:10699171
ARHGAP6Humannegative regulation of stress fiber assembly involved_inIMP 150520179 PMID:10699171BHF-UCLPMID:10699171
ARHGAP6Humanpositive regulation of GTPase activity involved_inISOArhgap6 (Mus musculus)9068941 PMID:10699171BHF-UCLPMID:10699171
ARHGAP6Humanpositive regulation of intracellular signal transduction involved_inIEAUniProtKB:O54834 and ensembl:ENSMUSP00000033721150520179 EnsemblGO_REF:0000107
ARHGAP6Humanpositive regulation of phospholipase C/protein kinase C signal transduction involved_inIDA 150520179 PMID:18434237BHF-UCLPMID:18434237
ARHGAP6Humanregulation of small GTPase mediated signal transduction involved_inTAS 150520179 ReactomeReactome:R-HSA-9012999
ARHGAP6HumanRho protein signal transduction involved_inNAS 150520179 PMID:10699171UniProtPMID:10699171
ARHGAP6HumanRho protein signal transduction involved_inTAS 150520179 PMID:9417914PINCPMID:9417914
ARHGAP6Humansignal transduction involved_inIEAInterPro:IPR000198150520179 InterProGO_REF:0000002
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Cellular Component
1 to 9 of 9 rows

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
ARHGAP6Humanactin cytoskeleton located_inIEAUniProtKB:O54834 and ensembl:ENSMUSP00000033721150520179 EnsemblGO_REF:0000107
ARHGAP6Humanactin cytoskeleton located_inISSUniProtKB:O54834150520179 PMID:10699171BHF-UCLPMID:10699171
ARHGAP6Humanactin filament located_inNAS 150520179 PMID:10699171UniProtPMID:10699171
ARHGAP6Humancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
ARHGAP6Humancytoplasm located_inIMP 150520179 PMID:10699171BHF-UCLPMID:10699171
ARHGAP6Humancytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
ARHGAP6Humancytosol located_inIDA 150520179 HPAGO_REF:0000052
ARHGAP6Humancytosol located_inTAS 150520179 ReactomeReactome:R-HSA-8981637 and Reactome:R-HSA-9018806
ARHGAP6Humanmitotic spindle located_inIDA 150520179 HPAGO_REF:0000052
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Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ARHGAP6HumanGTPase activator activity enablesIEAUniProtKB:O54834 and ensembl:ENSMUSP00000033721150520179 EnsemblGO_REF:0000107
ARHGAP6HumanGTPase activator activity enablesTAS 150520179 ReactomeReactome:R-HSA-8981637 and Reactome:R-HSA-9018806
ARHGAP6HumanGTPase activator activity enablesIEAUniProtKB-KW:KW-0343150520179 UniProtGO_REF:0000043
ARHGAP6Humanphospholipase activator activity enablesIDA 150520179 PMID:18434237BHF-UCLPMID:18434237
ARHGAP6Humanphospholipase binding enablesIPIUniProtKB:P51178150520179 PMID:18434237BHF-UCLPMID:18434237
ARHGAP6HumanSH3 domain binding enablesIEAUniProtKB-KW:KW-0729150520179 UniProtGO_REF:0000043

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ARHGAP6HumanAmelogenesis imperfecta  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Amelogenesis imperfectaClinVar 
ARHGAP6HumanAutism  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
ARHGAP6HumanAutism  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
ARHGAP6HumanIntellectual disability  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868
ARHGAP6HumanIntellectual disability  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868
ARHGAP6HumanPrimary amenorrhea  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Primary amenorrheaClinVarPMID:21681106

#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8570618   PMID:9417914   PMID:10699171   PMID:12477932   PMID:12673365   PMID:18434237   PMID:19913121   PMID:19960375   PMID:20628086   PMID:21873635   PMID:22889411   PMID:23251683  
PMID:25798074   PMID:28611215   PMID:30816546   PMID:32203420   PMID:34338998   PMID:35044719   PMID:36715867   PMID:37409526   PMID:37448957   PMID:38287795   PMID:38334954  



ARHGAP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,137,544 - 11,665,920 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,117,651 - 11,665,920 (-)EnsemblGRCh38hg38GRCh38
GRCh37X11,155,664 - 11,684,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X11,065,584 - 11,593,742 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X10,915,323 - 11,443,478NCBI
CeleraX15,283,114 - 15,812,107 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBIHuRef
CHM1_1X11,186,095 - 11,714,183 (-)NCBICHM1_1
T2T-CHM13v2.0X10,720,022 - 11,248,464 (-)NCBIT2T-CHM13v2.0
Arhgap6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X167,578,091 - 168,087,436 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX167,578,095 - 168,087,431 (+)EnsemblGRCm39 Ensembl
GRCm38X168,795,094 - 169,304,440 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX168,795,099 - 169,304,435 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X165,233,031 - 165,742,367 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X164,139,204 - 164,648,540 (+)NCBIMGSCv36mm8
CeleraX151,961,093 - 152,469,567 (+)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.77NCBI
Arhgap6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X28,525,912 - 29,062,344 (-)NCBIGRCr8
mRatBN7.2X24,953,464 - 25,490,003 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX24,953,464 - 25,488,663 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X26,314,561 - 26,845,242 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX26,315,878 - 26,376,467 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X26,719,353 - 27,249,921 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X45,638,826 - 46,180,012 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX25,373,362 - 25,904,033 (-)NCBICelera
Cytogenetic MapXq13NCBI
Arhgap6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555441,620,838 - 2,095,220 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555441,619,742 - 2,095,314 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X12,939,312 - 13,464,863 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X12,942,977 - 13,468,537 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X3,767,259 - 4,291,738 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X11,058,207 - 11,582,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX11,058,207 - 11,582,115 (-)Ensemblpanpan1.1panPan2
ARHGAP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X7,704,838 - 8,188,358 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX7,706,156 - 7,951,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX7,661,628 - 8,145,052 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X7,658,026 - 8,140,930 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX7,658,031 - 7,905,288 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X7,641,326 - 8,124,919 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X7,677,568 - 8,161,294 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X7,672,129 - 8,156,977 (-)NCBIUU_Cfam_GSD_1.0
Arhgap6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,048,141 - 1,501,946 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,049,461 - 1,500,877 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,048,145 - 1,501,970 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX7,910,858 - 8,120,386 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X7,910,851 - 8,441,579 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X8,541,109 - 8,686,000 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605611,312,486 - 11,345,780 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248822,708,089 - 3,211,766 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248822,706,827 - 3,211,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in ARHGAP6
139 total Variants

1 to 10 of 375 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
NC_000023.10:g.11285049_11381288del deletion Amelogenesis imperfecta, type 1E, with snow-capped teeth [RCV000033862] ChrX:11266933..11363172 [GRCh38]
ChrX:11285049..11381288 [GRCh37]
ChrX:Xp22.2
pathogenic
NC_000023.10:g.11633731_11797224del163494 deletion Intellectual disability [RCV000656445] ChrX:11633731..11797224 [GRCh37]
ChrX:Xp22.2
likely pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10701-156003242)x3 copy number gain See cases [RCV000133911] ChrX:10701..156003242 [GRCh38]
ChrX:60701..155232907 [GRCh37]
ChrX:701..154886101 [NCBI36]
ChrX:Xp22.33-q28
pathogenic|likely pathogenic|conflicting data from submitters
NM_013427.2(ARHGAP6):c.589-13852A>G single nucleotide variant Lung cancer [RCV000102209] ChrX:11268559 [GRCh38]
ChrX:11286679 [GRCh37]
ChrX:Xp22.2
uncertain significance
NM_013427.2(ARHGAP6):c.589-141305G>A single nucleotide variant Lung cancer [RCV000102223] ChrX:11396012 [GRCh38]
ChrX:11414132 [GRCh37]
ChrX:Xp22.2
uncertain significance
NM_013427.2(ARHGAP6):c.589-156092T>C single nucleotide variant Lung cancer [RCV000102225] ChrX:11410799 [GRCh38]
ChrX:11428919 [GRCh37]
ChrX:Xp22.2
uncertain significance
NM_013427.2(ARHGAP6):c.589-162939A>T single nucleotide variant Lung cancer [RCV000102226] ChrX:11417646 [GRCh38]
ChrX:11435766 [GRCh37]
ChrX:Xp22.2
uncertain significance
NM_013427.2(ARHGAP6):c.589-178573C>T single nucleotide variant Lung cancer [RCV000102228] ChrX:11433280 [GRCh38]
ChrX:11451400 [GRCh37]
ChrX:Xp22.2
uncertain significance
NM_013427.2(ARHGAP6):c.588+174447T>C single nucleotide variant Lung cancer [RCV000102232] ChrX:11489794 [GRCh38]
ChrX:11507914 [GRCh37]
ChrX:Xp22.2
uncertain significance
GRCh38/hg38 Xp22.33-q28(chrX:3092486-155699618)x2 copy number gain See cases [RCV000050889] ChrX:3092486..155699618 [GRCh38]
ChrX:3010527..154929279 [GRCh37]
ChrX:3020527..154582473 [NCBI36]
ChrX:Xp22.33-q28
pathogenic
1 to 10 of 375 rows

Predicted Target Of
Summary Value
Count of predictions:6528
Count of miRNA genes:1351
Interacting mature miRNAs:1762
Transcripts:ENST00000303025, ENST00000337414, ENST00000380717, ENST00000380718, ENST00000380732, ENST00000380736, ENST00000413512, ENST00000489330, ENST00000491514, ENST00000495242, ENST00000534860
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597150359GWAS1246433_Hprostate carcinoma QTL GWAS1246433 (human)9e-23prostate carcinomaX1146451411464515Human
597049749GWAS1145823_Hprostate carcinoma QTL GWAS1145823 (human)1e-08prostate carcinomaX1146451411464515Human
597107922GWAS1203996_Htestosterone measurement QTL GWAS1203996 (human)4e-10testosterone measurementserum testosterone level (CMO:0000568)X1119106411191065Human
597101106GWAS1197180_Hprostate carcinoma QTL GWAS1197180 (human)1e-12prostate carcinomaX1146451411464515Human
597051006GWAS1147080_Hprostate carcinoma QTL GWAS1147080 (human)2e-13prostate carcinomaX1146451411464515Human
597150360GWAS1246434_Hprostate carcinoma QTL GWAS1246434 (human)1e-09prostate carcinomaX1144395411443955Human
597147366GWAS1243440_Hprostate carcinoma QTL GWAS1243440 (human)3e-08prostate carcinomaX1144395411443955Human
597211626GWAS1307700_Hvelopharyngeal dysfunction QTL GWAS1307700 (human)0.000002velopharyngeal dysfunctionX1129229911292300Human
597147365GWAS1243439_Hprostate carcinoma QTL GWAS1243439 (human)1e-21prostate carcinomaX1146451411464515Human
597211627GWAS1307701_Hvelopharyngeal dysfunction QTL GWAS1307701 (human)0.000003velopharyngeal dysfunctionX1155272911552730Human

1 to 10 of 17 rows
DXS1043  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,468,259 - 11,468,412UniSTSGRCh37
GRCh37X11,468,251 - 11,468,398UniSTSGRCh37
Build 36X11,378,172 - 11,378,319RGDNCBI36
CeleraX15,595,722 - 15,595,875UniSTS
CeleraX15,595,714 - 15,595,861RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,247,290 - 9,247,437UniSTS
HuRefX9,247,298 - 9,247,451UniSTS
Marshfield Genetic MapX18.37RGD
Genethon Genetic MapX17.7UniSTS
TNG Radiation Hybrid MapX2197.0UniSTS
deCODE Assembly MapX21.33UniSTS
Stanford-G3 RH MapX840.0UniSTS
GeneMap99-GB4 RH MapX83.98UniSTS
Whitehead-RH MapX7.7UniSTS
Whitehead-YAC Contig MapX UniSTS
NCBI RH MapX10.7UniSTS
GeneMap99-G3 RH MapX26.0UniSTS
D11S1905  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,192,307 - 11,192,858UniSTSGRCh37
CeleraX15,319,758 - 15,320,309UniSTS
Cytogenetic MapXp22.3UniSTS
Marshfield Genetic Map1142.55UniSTS
Marshfield Genetic Map1142.55RGD
DXS7090  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,497,394 - 11,497,585UniSTSGRCh37
Build 36X11,407,315 - 11,407,506RGDNCBI36
CeleraX15,624,857 - 15,625,048RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,276,256 - 9,276,447UniSTS
Whitehead-RH MapX9.4UniSTS
Whitehead-YAC Contig MapX UniSTS
NCBI RH MapX10.0UniSTS
RH79902  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,317,122 - 11,317,314UniSTSGRCh37
Build 36X11,227,043 - 11,227,235RGDNCBI36
CeleraX15,444,579 - 15,444,771RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
HuRefX9,096,745 - 9,096,937UniSTS
RH98500  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,155,714 - 11,155,863UniSTSGRCh37
Build 36X11,065,635 - 11,065,784RGDNCBI36
CeleraX15,283,165 - 15,283,314RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,936,170 - 8,936,319UniSTS
GeneMap99-GB4 RH MapX83.98UniSTS
AF003642  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,220,867 - 11,221,035UniSTSGRCh37
Build 36X11,130,788 - 11,130,956RGDNCBI36
CeleraX15,348,320 - 15,348,488RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,000,333 - 9,000,502UniSTS
AF003643  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,203,197 - 11,203,360UniSTSGRCh37
Build 36X11,113,118 - 11,113,281RGDNCBI36
CeleraX15,330,648 - 15,330,811RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,983,039 - 8,983,202UniSTS
AF003645  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,232,191 - 11,232,456UniSTSGRCh37
Build 36X11,142,112 - 11,142,377RGDNCBI36
CeleraX15,359,644 - 15,359,911RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,011,659 - 9,011,926UniSTS
AF003646  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,284,082 - 11,284,317UniSTSGRCh37
Build 36X11,194,003 - 11,194,238RGDNCBI36
CeleraX15,411,538 - 15,411,773RGD
Cytogenetic MapXp22.3UniSTS
AF003647  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,220,081 - 11,220,244UniSTSGRCh37
Build 36X11,130,002 - 11,130,165RGDNCBI36
CeleraX15,347,532 - 15,347,697RGD
Cytogenetic MapXp22.3UniSTS
AF003648  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,259,537 - 11,259,739UniSTSGRCh37
Build 36X11,169,458 - 11,169,660RGDNCBI36
CeleraX15,386,993 - 15,387,195RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,039,108 - 9,039,310UniSTS
AF003655  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,338,845 - 11,339,019UniSTSGRCh37
Build 36X11,248,766 - 11,248,940RGDNCBI36
CeleraX15,466,300 - 15,466,478RGD
Cytogenetic MapXp22.3UniSTS
AF003672  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,156,200 - 11,156,421UniSTSGRCh37
Build 36X11,066,121 - 11,066,342RGDNCBI36
CeleraX15,283,651 - 15,283,872RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,936,656 - 8,936,877UniSTS
AF003685  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,184,705 - 11,184,878UniSTSGRCh37
Build 36X11,094,626 - 11,094,799RGDNCBI36
CeleraX15,312,156 - 15,312,329RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,964,627 - 8,964,800UniSTS
DXF22S5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,260,594 - 11,260,787UniSTSGRCh37
Build 36X11,170,515 - 11,170,708RGDNCBI36
CeleraX15,388,050 - 15,388,243RGD
Cytogenetic MapXp22.3UniSTS
DXS1380  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,451,793 - 11,451,896UniSTSGRCh37
Build 36X11,361,714 - 11,361,817RGDNCBI36
CeleraX15,579,256 - 15,579,359RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,230,907 - 9,231,010UniSTS
DXS1445  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,581,372 - 11,581,514UniSTSGRCh37
Build 36X11,491,293 - 11,491,435RGDNCBI36
CeleraX15,708,477 - 15,708,619RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,359,477 - 9,359,619UniSTS
DXS1129  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,649,156 - 11,649,342UniSTSGRCh37
Build 36X11,559,077 - 11,559,263RGDNCBI36
CeleraX15,777,447 - 15,777,633RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,428,083 - 9,428,269UniSTS
DXS1135  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,519,985 - 11,520,256UniSTSGRCh37
Build 36X11,429,906 - 11,430,177RGDNCBI36
CeleraX15,647,828 - 15,648,099RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,299,394 - 9,299,665UniSTS
GDB:677393  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,315,324 - 11,315,473UniSTSGRCh37
Build 36X11,225,245 - 11,225,394RGDNCBI36
CeleraX15,442,781 - 15,442,930RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
HuRefX9,094,947 - 9,095,096UniSTS
SHGC-80932  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,321,091 - 11,321,382UniSTSGRCh37
Build 36X11,231,012 - 11,231,303RGDNCBI36
CeleraX15,448,547 - 15,448,838RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,100,564 - 9,100,855UniSTS
TNG Radiation Hybrid MapX2227.0UniSTS
SHGC-84186  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,451,596 - 11,451,882UniSTSGRCh37
Build 36X11,361,517 - 11,361,803RGDNCBI36
CeleraX15,579,059 - 15,579,345RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,230,710 - 9,230,996UniSTS
TNG Radiation Hybrid MapX2204.0UniSTS
RH123869  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,172,765 - 11,173,063UniSTSGRCh37
Build 36X11,082,686 - 11,082,984RGDNCBI36
CeleraX15,300,216 - 15,300,514RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,952,706 - 8,953,004UniSTS
TNG Radiation Hybrid MapX2281.0UniSTS
G62689  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,548,837 - 11,549,130UniSTSGRCh37
Build 36X11,458,758 - 11,459,051RGDNCBI36
CeleraX15,675,772 - 15,676,065RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,327,265 - 9,327,558UniSTS
TNG Radiation Hybrid MapX2182.0UniSTS
G42692  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,316,604 - 11,316,668UniSTSGRCh37
GRCh37Y6,736,503 - 6,736,567UniSTSGRCh37
Build 36X11,226,525 - 11,226,589RGDNCBI36
CeleraX15,444,061 - 15,444,125RGD
CeleraY2,479,480 - 2,479,544UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic MapYp11.2UniSTS
Cytogenetic MapXp22.31-p22.1UniSTS
HuRefX9,096,227 - 9,096,291UniSTS
HuRefY4,295,557 - 4,295,621UniSTS
DXS7543  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,164,658 - 11,164,761UniSTSGRCh37
Build 36X11,074,579 - 11,074,682RGDNCBI36
CeleraX15,292,109 - 15,292,212RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,945,114 - 8,945,217UniSTS
DXS7928  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,167,562 - 11,167,668UniSTSGRCh37
Build 36X11,077,483 - 11,077,589RGDNCBI36
CeleraX15,295,013 - 15,295,119RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,947,424 - 8,947,530UniSTS
GDB:371402  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,316,279 - 11,316,650UniSTSGRCh37
Build 36X11,226,200 - 11,226,571RGDNCBI36
CeleraX15,443,736 - 15,444,107RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
HuRefX9,095,902 - 9,096,273UniSTS
GDB:574117  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,312,849 - 11,313,028UniSTSGRCh37
Build 36X11,222,770 - 11,222,949RGDNCBI36
CeleraX15,440,306 - 15,440,485RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
HuRefX9,092,472 - 9,092,651UniSTS
GDB:574121  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,314,737 - 11,315,050UniSTSGRCh37
Build 36X11,224,658 - 11,224,971RGDNCBI36
CeleraX15,442,194 - 15,442,507RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
HuRefX9,094,360 - 9,094,673UniSTS
GDB:574132  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,316,059 - 11,316,524UniSTSGRCh37
GRCh37Y6,736,647 - 6,737,115UniSTSGRCh37
Build 36X11,225,980 - 11,226,445RGDNCBI36
CeleraX15,443,516 - 15,443,981RGD
CeleraY2,478,932 - 2,479,400UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic MapYp11.2UniSTS
Cytogenetic MapXp22.31-p22.1UniSTS
HuRefX9,095,682 - 9,096,147UniSTS
HuRefY4,295,701 - 4,296,169UniSTS
GDB:574144  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,316,632 - 11,317,187UniSTSGRCh37
Build 36X11,226,553 - 11,227,108RGDNCBI36
CeleraX15,444,089 - 15,444,644RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
HuRefX9,096,255 - 9,096,810UniSTS
GDB:574146  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,317,520 - 11,318,872UniSTSGRCh37
Build 36X11,227,441 - 11,228,793RGDNCBI36
CeleraX15,444,977 - 15,446,329RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
SHGC-108012  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,499,022 - 11,499,328UniSTSGRCh37
Build 36X11,408,943 - 11,409,249RGDNCBI36
CeleraX15,626,485 - 15,626,791RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,278,328 - 9,278,634UniSTS
TNG Radiation Hybrid MapX2189.0UniSTS
RH46956  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,317,385 - 11,317,515UniSTSGRCh37
Build 36X11,227,306 - 11,227,436RGDNCBI36
CeleraX15,444,842 - 15,444,972RGD
Cytogenetic MapXp22.31-p22.1UniSTS
Cytogenetic MapXp22.3UniSTS
GeneMap99-GB4 RH MapX83.98UniSTS
NCBI RH MapX10.0UniSTS
SHGC-105133  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,633,711 - 11,634,033UniSTSGRCh37
Build 36X11,543,632 - 11,543,954RGDNCBI36
CeleraX15,762,162 - 15,762,484RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,412,327 - 9,412,649UniSTS
TNG Radiation Hybrid MapX2141.0UniSTS
AMELX  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37Y6,736,086 - 6,736,302UniSTSGRCh37
GRCh37X11,316,869 - 11,317,085UniSTSGRCh37
Build 36X11,226,790 - 11,227,006RGDNCBI36
CeleraY2,479,745 - 2,479,961UniSTS
CeleraX15,444,326 - 15,444,542RGD
HuRefY4,295,140 - 4,295,356UniSTS
HuRefX9,096,492 - 9,096,708UniSTS
DXS7519  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,204,783 - 11,204,918UniSTSGRCh37
Build 36X11,114,704 - 11,114,839RGDNCBI36
CeleraX15,332,234 - 15,332,369RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,984,625 - 8,984,760UniSTS
Whitehead-YAC Contig MapX UniSTS
DXS9824  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,391,128 - 11,391,356UniSTSGRCh37
Build 36X11,301,049 - 11,301,277RGDNCBI36
CeleraX15,518,587 - 15,518,815RGD
HuRefX9,170,639 - 9,170,867UniSTS
DXS9825  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,371,275 - 11,371,745UniSTSGRCh37
Build 36X11,281,196 - 11,281,666RGDNCBI36
CeleraX15,498,733 - 15,499,205RGD
HuRefX9,150,578 - 9,151,050UniSTS
AFMa052zc1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,369,112 - 11,369,266UniSTSGRCh37
Build 36X11,279,033 - 11,279,187RGDNCBI36
CeleraX15,496,570 - 15,496,724RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,148,411 - 9,148,569UniSTS
Whitehead-RH MapX3.9UniSTS
Whitehead-YAC Contig MapX UniSTS
NCBI RH MapX10.0UniSTS
DXS7800  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,187,488 - 11,187,602UniSTSGRCh37
Build 36X11,097,409 - 11,097,523RGDNCBI36
CeleraX15,314,939 - 15,315,053RGD
Cytogenetic MapXp22.3UniSTS
HuRefX8,967,410 - 8,967,524UniSTS
SHGC-34710  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,270,570 - 11,270,719UniSTSGRCh37
Build 36X11,180,491 - 11,180,640RGDNCBI36
CeleraX15,398,026 - 15,398,175RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,050,364 - 9,050,513UniSTS
Stanford-G3 RH MapX828.0UniSTS
GeneMap99-GB4 RH MapX83.98UniSTS
Whitehead-RH MapX6.1UniSTS
NCBI RH MapX10.0UniSTS
GeneMap99-G3 RH MapX13.0UniSTS
DXS8202  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,281,076 - 11,281,245UniSTSGRCh37
Build 36X11,190,997 - 11,191,166RGDNCBI36
CeleraX15,408,532 - 15,408,701RGD
Cytogenetic MapXp22.3UniSTS
HuRefX9,060,665 - 9,060,834UniSTS
ARHGAP6_4363  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X11,161,513 - 11,162,315UniSTSGRCh37
Build 36X11,071,434 - 11,072,236RGDNCBI36
CeleraX15,288,964 - 15,289,766RGD
HuRefX8,941,969 - 8,942,771UniSTS
DXS1043  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXp22.3UniSTS
Marshfield Genetic MapX18.37UniSTS
Genethon Genetic MapX17.7UniSTS
deCODE Assembly MapX21.33UniSTS
GeneMap99-GB4 RH MapX83.98UniSTS
Whitehead-RH MapX7.7UniSTS
Whitehead-YAC Contig MapX UniSTS
NCBI RH MapX10.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2371 2788 2229 4909 1704 2223 3 611 1836 451 2242 7129 6355 33 3697 841 1706 1505 169 1


1 to 28 of 28 rows
RefSeq Transcripts NG_012494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001287242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_109776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB208792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC002366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC003657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF012272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF117067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF177663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF177665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY018118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 28 of 28 rows

Ensembl Acc Id: ENST00000303025   ⟹   ENSP00000302312
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,137,544 - 11,265,975 (-)Ensembl
Ensembl Acc Id: ENST00000337414   ⟹   ENSP00000338967
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,137,544 - 11,665,920 (-)Ensembl
Ensembl Acc Id: ENST00000380717   ⟹   ENSP00000370093
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,143,397 - 11,290,478 (-)Ensembl
Ensembl Acc Id: ENST00000380718   ⟹   ENSP00000370094
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,143,397 - 11,665,701 (-)Ensembl
Ensembl Acc Id: ENST00000380736   ⟹   ENSP00000370112
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,137,543 - 11,427,773 (-)Ensembl
Ensembl Acc Id: ENST00000489330
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,137,547 - 11,665,083 (-)Ensembl
Ensembl Acc Id: ENST00000491514
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,169,156 - 11,182,074 (-)Ensembl
Ensembl Acc Id: ENST00000495242   ⟹   ENSP00000435767
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,137,544 - 11,665,701 (-)Ensembl
Ensembl Acc Id: ENST00000657361   ⟹   ENSP00000499351
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX11,117,651 - 11,266,004 (-)Ensembl
RefSeq Acc Id: NM_001287242   ⟹   NP_001274171
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,137,544 - 11,427,818 (-)NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBI
CHM1_1X11,186,095 - 11,476,315 (-)NCBI
T2T-CHM13v2.0X10,720,022 - 11,010,322 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006125   ⟹   NP_006116
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,143,397 - 11,665,920 (-)NCBI
GRCh37X11,155,663 - 11,683,821 (-)RGD
Build 36X11,071,438 - 11,593,742 (-)NCBI Archive
CeleraX15,283,114 - 15,812,107 (-)RGD
HuRefX8,936,119 - 9,462,624 (-)RGD
CHM1_1X11,191,951 - 11,714,183 (-)NCBI
T2T-CHM13v2.0X10,725,875 - 11,248,464 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013423   ⟹   NP_038267
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,137,544 - 11,265,992 (-)NCBI
GRCh37X11,155,663 - 11,683,821 (-)RGD
Build 36X11,065,584 - 11,194,016 (-)NCBI Archive
CeleraX15,283,114 - 15,812,107 (-)RGD
HuRefX8,936,119 - 9,462,624 (-)RGD
CHM1_1X11,186,095 - 11,314,563 (-)NCBI
T2T-CHM13v2.0X10,720,022 - 10,848,494 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013427   ⟹   NP_038286
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,137,544 - 11,665,920 (-)NCBI
GRCh37X11,155,663 - 11,683,821 (-)RGD
Build 36X11,065,584 - 11,593,742 (-)NCBI Archive
CeleraX15,283,114 - 15,812,107 (-)RGD
HuRefX8,936,119 - 9,462,624 (-)RGD
CHM1_1X11,186,095 - 11,714,183 (-)NCBI
T2T-CHM13v2.0X10,720,022 - 11,248,464 (-)NCBI
Sequence:
RefSeq Acc Id: NR_109776
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,137,544 - 11,665,920 (-)NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBI
CHM1_1X11,186,095 - 11,714,183 (-)NCBI
T2T-CHM13v2.0X10,720,022 - 11,248,464 (-)NCBI
Sequence:
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_038286   ⟸   NM_013427
- Peptide Label: isoform 1
- UniProtKB: Q9UK81 (UniProtKB/Swiss-Prot),   Q9P1B3 (UniProtKB/Swiss-Prot),   O43437 (UniProtKB/Swiss-Prot),   B2RWQ0 (UniProtKB/Swiss-Prot),   Q9UK82 (UniProtKB/Swiss-Prot),   O43182 (UniProtKB/Swiss-Prot),   A8KAL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_038267   ⟸   NM_013423
- Peptide Label: isoform 4
- UniProtKB: O43182 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_006116   ⟸   NM_006125
- Peptide Label: isoform 3
- UniProtKB: Q59HG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001274171   ⟸   NM_001287242
- Peptide Label: isoform 6
- UniProtKB: A8KAL3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000338967   ⟸   ENST00000337414
Rho-GAP

Name Modeler Protein Id AA Range Protein Structure
AF-O43182-F1-model_v2 AlphaFold O43182 1-974 view protein structure

RGD ID:6808499
Promoter ID:HG_KWN:65989
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat
Transcripts:OTTHUMT00000055765
Position:
Human AssemblyChrPosition (strand)Source
Build 36X11,110,136 - 11,110,636 (-)MPROMDB
RGD ID:6808502
Promoter ID:HG_KWN:65990
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000353663,   NM_013423
Position:
Human AssemblyChrPosition (strand)Source
Build 36X11,193,941 - 11,194,441 (-)MPROMDB
RGD ID:13604728
Promoter ID:EPDNEW_H28548
Type:initiation region
Name:ARHGAP6_2
Description:Rho GTPase activating protein 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28550  EPDNEW_H28551  EPDNEW_H28552  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,265,992 - 11,266,052EPDNEW
RGD ID:6808498
Promoter ID:HG_KWN:65994
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:ENST00000380736
Position:
Human AssemblyChrPosition (strand)Source
Build 36X11,355,429 - 11,355,929 (-)MPROMDB
RGD ID:13604732
Promoter ID:EPDNEW_H28550
Type:multiple initiation site
Name:ARHGAP6_4
Description:Rho GTPase activating protein 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28548  EPDNEW_H28551  EPDNEW_H28552  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,398,260 - 11,398,320EPDNEW
RGD ID:13604734
Promoter ID:EPDNEW_H28551
Type:initiation region
Name:ARHGAP6_1
Description:Rho GTPase activating protein 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28548  EPDNEW_H28550  EPDNEW_H28552  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,427,786 - 11,427,846EPDNEW
RGD ID:6808501
Promoter ID:HG_KWN:65995
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:ENST00000380717,   NM_006125,   NM_013427,   OTTHUMT00000055761,   OTTHUMT00000291400
Position:
Human AssemblyChrPosition (strand)Source
Build 36X11,592,811 - 11,594,327 (-)MPROMDB
RGD ID:13604736
Promoter ID:EPDNEW_H28552
Type:initiation region
Name:ARHGAP6_3
Description:Rho GTPase activating protein 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28548  EPDNEW_H28550  EPDNEW_H28551  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X11,665,920 - 11,665,980EPDNEW


1 to 40 of 45 rows
Database
Acc Id
Source(s)
COSMIC ARHGAP6 COSMIC
Ensembl Genes ENSG00000047648 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000303025 ENTREZGENE
  ENST00000303025.10 UniProtKB/Swiss-Prot
  ENST00000337414 ENTREZGENE
  ENST00000337414.9 UniProtKB/Swiss-Prot
  ENST00000380718 ENTREZGENE
  ENST00000380718.1 UniProtKB/Swiss-Prot
  ENST00000380736.5 UniProtKB/Swiss-Prot
  ENST00000495242 ENTREZGENE
  ENST00000495242.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot
GTEx ENSG00000047648 GTEx
HGNC ID HGNC:676 ENTREZGENE
Human Proteome Map ARHGAP6 Human Proteome Map
InterPro ARHGAP6_RhoGAP UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot
  RHOGAP6/36 UniProtKB/Swiss-Prot
  RhoGAP_dom UniProtKB/Swiss-Prot
KEGG Report hsa:395 UniProtKB/Swiss-Prot
NCBI Gene 395 ENTREZGENE
OMIM 300118 OMIM
PANTHER PTHR12635 UniProtKB/Swiss-Prot
  PTHR12635:SF6 UniProtKB/Swiss-Prot
Pfam RhoGAP UniProtKB/Swiss-Prot
PharmGKB PA24960 PharmGKB
PROSITE RHOGAP UniProtKB/Swiss-Prot
SMART RhoGAP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot
UniProt A8KAL3 ENTREZGENE, UniProtKB/TrEMBL
  B2RWQ0 ENTREZGENE
  B4DN07_HUMAN UniProtKB/TrEMBL
  H7BYE6_HUMAN UniProtKB/TrEMBL
  O43182 ENTREZGENE
  O43437 ENTREZGENE
  Q59HG6 ENTREZGENE, UniProtKB/TrEMBL
  Q9P1B3 ENTREZGENE
  Q9UK81 ENTREZGENE
  Q9UK82 ENTREZGENE
  RHG06_HUMAN UniProtKB/Swiss-Prot
1 to 40 of 45 rows