Arhgap6 (Rho GTPase activating protein 6) - Rat Genome Database

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Gene: Arhgap6 (Rho GTPase activating protein 6) Ictidomys tridecemlineatus
Analyze
Symbol: Arhgap6
Name: Rho GTPase activating protein 6
RGD ID: 12505519
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); phospholipase activator activity (inferred); phospholipase binding (inferred); INVOLVED IN actin filament organization (ortholog); focal adhesion assembly (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1E (ortholog); amenorrhea (ortholog); FOUND IN actin cytoskeleton (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,048,141 - 1,501,946 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,049,461 - 1,500,877 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,048,145 - 1,501,970 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Arhgap6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,048,141 - 1,501,946 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,049,461 - 1,500,877 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,048,145 - 1,501,970 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,137,544 - 11,665,920 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,117,651 - 11,665,920 (-)EnsemblGRCh38hg38GRCh38
GRCh37X11,155,664 - 11,684,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X11,065,584 - 11,593,742 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X10,915,323 - 11,443,478NCBI
CeleraX15,283,114 - 15,812,107 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBIHuRef
CHM1_1X11,186,095 - 11,714,183 (-)NCBICHM1_1
T2T-CHM13v2.0X10,720,022 - 11,248,464 (-)NCBIT2T-CHM13v2.0
Arhgap6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X167,578,091 - 168,087,436 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX167,578,095 - 168,087,431 (+)EnsemblGRCm39 Ensembl
GRCm38X168,795,094 - 169,304,440 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX168,795,099 - 169,304,435 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X165,233,031 - 165,742,367 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X164,139,204 - 164,648,540 (+)NCBIMGSCv36mm8
CeleraX151,961,093 - 152,469,567 (+)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.77NCBI
Arhgap6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X28,525,912 - 29,062,344 (-)NCBIGRCr8
mRatBN7.2X24,953,464 - 25,490,003 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX24,953,464 - 25,488,663 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X26,314,561 - 26,845,242 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX26,315,878 - 26,376,467 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X26,719,353 - 27,249,921 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X45,638,826 - 46,180,012 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX25,373,362 - 25,904,033 (-)NCBICelera
Cytogenetic MapXq13NCBI
Arhgap6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555441,620,838 - 2,095,220 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555441,619,742 - 2,095,314 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X12,939,312 - 13,464,863 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X12,942,977 - 13,468,537 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X3,767,259 - 4,291,738 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X11,058,207 - 11,582,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX11,058,207 - 11,582,115 (-)Ensemblpanpan1.1panPan2
ARHGAP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X7,704,838 - 8,188,358 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX7,706,156 - 7,951,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX7,661,628 - 8,145,052 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X7,658,026 - 8,140,930 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX7,658,031 - 7,905,288 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X7,641,326 - 8,124,919 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X7,677,568 - 8,161,294 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X7,672,129 - 8,156,977 (-)NCBIUU_Cfam_GSD_1.0
ARHGAP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX7,910,858 - 8,120,386 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X7,910,851 - 8,441,579 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X8,541,109 - 8,686,000 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103231590
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X9,595,772 - 10,165,129 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX9,597,101 - 9,656,573 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605611,393,641 - 11,444,844 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248822,708,089 - 3,211,766 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248822,706,827 - 3,211,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000014043   ⟹   ENSSTOP00000012583
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364701,049,461 - 1,286,433 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000033120   ⟹   ENSSTOP00000025217
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364701,049,461 - 1,500,877 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000040190   ⟹   ENSSTOP00000031949
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364701,049,461 - 1,223,389 (-)Ensembl
RefSeq Acc Id: XM_040287666   ⟹   XP_040143600
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X1,048,141 - 1,501,946 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040143600 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012583.3
  ENSSTOP00000025217.1
  ENSSTOP00000031949.1
GenBank Protein KAG3271691 (Get FASTA)   NCBI Sequence Viewer  
  KAG3271692 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040143600   ⟸   XM_040287666
- UniProtKB: A0A287CV86 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000025217   ⟸   ENSSTOT00000033120
RefSeq Acc Id: ENSSTOP00000012583   ⟸   ENSSTOT00000014043
RefSeq Acc Id: ENSSTOP00000031949   ⟸   ENSSTOT00000040190
Protein Domains
Rho-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014042 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014043.3 UniProtKB/TrEMBL
  ENSSTOT00000033120.1 UniProtKB/TrEMBL
  ENSSTOT00000040190.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
InterPro ARHGAP6_RhoGAP UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RHOGAP6/36 UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene Arhgap6 ENTREZGENE
PANTHER PTHR12635 UniProtKB/TrEMBL
  PTHR12635:SF6 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
UniProt A0A287CV86 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DEI9_ICTTR UniProtKB/TrEMBL
  I3MM63_ICTTR UniProtKB/TrEMBL