MRPS18B (mitochondrial ribosomal protein S18B) - Rat Genome Database

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Gene: MRPS18B (mitochondrial ribosomal protein S18B) Homo sapiens
Analyze
Symbol: MRPS18B
Name: mitochondrial ribosomal protein S18B
RGD ID: 1349132
HGNC Page HGNC:14516
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in cell junction; mitochondrion; and nucleoplasm. Part of mitochondrial small ribosomal subunit.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial; C6orf14; DKFZp564H0223; HSPC183; HumanS18a; mitochondrial ribosomal protein S18-2; mitochondrial small ribosomal subunit protein bS18b; mitochondrial small ribosomal subunit protein bS18m-B; mitochondrial small ribosomal subunit protein mS40; MRP-S18-2; MRP-S18-b; MRPS18-2; mrps18-b; mS40; PTD017; S18amt; S18mt-b; small ribosomal subunit protein bS18b; small ribosomal subunit protein mS40
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: MRPS18BP1   MRPS18BP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,617,840 - 30,626,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,617,840 - 30,626,395 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,585,617 - 30,594,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,693,585 - 30,702,148 (+)NCBINCBI36Build 36hg18NCBI36
Build 34630,693,584 - 30,702,146NCBI
Celera632,183,604 - 32,192,292 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef630,385,654 - 30,394,342 (+)NCBIHuRef
CHM1_1630,587,595 - 30,596,284 (+)NCBICHM1_1
T2T-CHM13v2.0630,482,021 - 30,490,573 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
acrylamide  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
aristolochic acid A  (EXP)
atrazine  (EXP)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (EXP,ISO)
clofibric acid  (ISO)
clomipramine  (ISO)
copper(II) sulfate  (EXP)
cyproconazole  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (EXP)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
finasteride  (ISO)
flutamide  (ISO)
FR900359  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
glyphosate  (ISO)
imidacloprid  (ISO)
imipramine  (ISO)
indometacin  (EXP)
ivermectin  (EXP)
ketoconazole  (ISO)
lipopolysaccharide  (EXP)
methapyrilene  (ISO)
methidathion  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel sulfate  (EXP)
nimesulide  (ISO)
ozone  (ISO)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
tamoxifen  (ISO)
temozolomide  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
thiabendazole  (ISO)
titanium dioxide  (ISO)
triadimefon  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triptonide  (ISO)
trovafloxacin  (ISO)
tunicamycin  (EXP)
valdecoxib  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. Cavdar Koc E, etal., J Biol Chem 2001 Jun 1;276(22):19363-74. Epub 2001 Mar 02.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11042152   PMID:11402041   PMID:12477932   PMID:12706105   PMID:15231747   PMID:15342556   PMID:15489334   PMID:16189514   PMID:16196087   PMID:16702430   PMID:17086389   PMID:17353931  
PMID:18391203   PMID:19851445   PMID:20186120   PMID:20360068   PMID:20877624   PMID:21139048   PMID:21145461   PMID:21873635   PMID:22003127   PMID:22658674   PMID:22939629   PMID:23443559  
PMID:23892058   PMID:24189400   PMID:24244333   PMID:24816145   PMID:25324306   PMID:25437307   PMID:25838379   PMID:26023799   PMID:26186194   PMID:26344197   PMID:26472337   PMID:26485645  
PMID:26496610   PMID:26549023   PMID:26959119   PMID:27023846   PMID:27489352   PMID:28077445   PMID:28302793   PMID:28361860   PMID:28514442   PMID:28515276   PMID:28655764   PMID:28675297  
PMID:28712289   PMID:29128334   PMID:29229926   PMID:29395067   PMID:29396484   PMID:29568061   PMID:29721183   PMID:29802200   PMID:29845934   PMID:29955894   PMID:30021884   PMID:30033366  
PMID:30209976   PMID:30344098   PMID:30471916   PMID:30581152   PMID:30593750   PMID:30833792   PMID:31091453   PMID:31343991   PMID:31527615   PMID:31540324   PMID:31586073   PMID:31722399  
PMID:31822558   PMID:31871319   PMID:32203420   PMID:32296183   PMID:32571933   PMID:32640226   PMID:32687490   PMID:32707033   PMID:32807901   PMID:32877691   PMID:33187986   PMID:33226137  
PMID:33301849   PMID:33306668   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34591434   PMID:34732716   PMID:35013218   PMID:35140242   PMID:35256949   PMID:35271311   PMID:35384245  
PMID:35446349   PMID:35819319   PMID:35831314   PMID:35944360   PMID:36215168   PMID:36244648   PMID:36282215   PMID:36526897   PMID:36537216   PMID:36574265   PMID:36779763   PMID:36912080  
PMID:38113892  


Genomics

Comparative Map Data
MRPS18B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,617,840 - 30,626,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,617,840 - 30,626,395 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,585,617 - 30,594,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,693,585 - 30,702,148 (+)NCBINCBI36Build 36hg18NCBI36
Build 34630,693,584 - 30,702,146NCBI
Celera632,183,604 - 32,192,292 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef630,385,654 - 30,394,342 (+)NCBIHuRef
CHM1_1630,587,595 - 30,596,284 (+)NCBICHM1_1
T2T-CHM13v2.0630,482,021 - 30,490,573 (+)NCBIT2T-CHM13v2.0
Mrps18b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,221,272 - 36,227,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,221,271 - 36,227,281 (-)EnsemblGRCm39 Ensembl
GRCm381735,910,380 - 35,916,440 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,910,379 - 35,916,389 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,047,330 - 36,053,314 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,518,438 - 35,524,422 (-)NCBIMGSCv36mm8
Celera1739,419,647 - 39,425,606 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.76NCBI
Mrps18b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8202,842,978 - 2,849,065 (+)NCBIGRCr8
mRatBN7.2202,838,174 - 2,844,260 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,838,030 - 2,844,260 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,889,984 - 2,896,037 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0202,894,954 - 2,901,007 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0202,921,099 - 2,927,165 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,344,870 - 3,350,929 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,344,870 - 3,350,927 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,442,393 - 5,448,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4202,985,972 - 2,992,031 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1202,986,225 - 2,992,253 (+)NCBI
Celera20264,183 - 270,242 (+)NCBICelera
Cytogenetic Map20p12NCBI
Mrps18b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583635,697 - 641,885 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955583635,697 - 641,885 (+)NCBIChiLan1.0ChiLan1.0
MRPS18B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,175,270 - 45,184,206 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,138,461 - 41,147,399 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,360,136 - 30,368,735 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,230,124 - 31,237,970 (+)NCBIpanpan1.1PanPan1.1panPan2
MRPS18B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112435,117 - 441,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12435,180 - 441,161 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12572,758 - 579,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.012579,258 - 585,768 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12579,317 - 585,764 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112435,808 - 442,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012505,092 - 511,380 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012574,914 - 581,424 (+)NCBIUU_Cfam_GSD_1.0
Mrps18b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494633,928,495 - 33,934,850 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936837294,654 - 299,857 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936837293,792 - 300,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPS18B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,165,946 - 23,172,998 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,166,314 - 23,172,718 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2726,835,923 - 26,842,328 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRPS18B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11741,830,763 - 41,839,026 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604430,310,936 - 30,320,525 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrps18b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,069,854 - 25,076,104 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,069,857 - 25,076,044 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MRPS18B
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33
pathogenic
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33
pathogenic
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.1-21.32(chr6:28130359-32108367)x3 copy number gain not provided [RCV000745592] Chr6:28130359..32108367 [GRCh37]
Chr6:6p22.1-21.32
uncertain significance
NM_014046.4(MRPS18B):c.622C>T (p.Pro208Ser) single nucleotide variant Inborn genetic diseases [RCV003241318] Chr6:30625642 [GRCh38]
Chr6:30593419 [GRCh37]
Chr6:6p21.33
uncertain significance
NC_000006.11:g.28005012_31683185del deletion Megacolon [RCV001290055] Chr6:28005012..31683185 [GRCh37]
Chr6:6p22.1-21.33
likely pathogenic
NM_014046.4(MRPS18B):c.446G>A (p.Arg149Gln) single nucleotide variant Inborn genetic diseases [RCV002969230] Chr6:30624907 [GRCh38]
Chr6:30592684 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.217G>A (p.Val73Ile) single nucleotide variant Inborn genetic diseases [RCV002990410] Chr6:30619738 [GRCh38]
Chr6:30587515 [GRCh37]
Chr6:6p21.33
likely benign
NM_014046.4(MRPS18B):c.248G>A (p.Gly83Asp) single nucleotide variant Inborn genetic diseases [RCV002782697] Chr6:30619769 [GRCh38]
Chr6:30587546 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.43A>G (p.Met15Val) single nucleotide variant Inborn genetic diseases [RCV002784923] Chr6:30617908 [GRCh38]
Chr6:30585685 [GRCh37]
Chr6:6p21.33
likely benign
NM_014046.4(MRPS18B):c.653G>A (p.Arg218Gln) single nucleotide variant Inborn genetic diseases [RCV002699176] Chr6:30625673 [GRCh38]
Chr6:30593450 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.330T>G (p.Asp110Glu) single nucleotide variant Inborn genetic diseases [RCV002916997] Chr6:30619965 [GRCh38]
Chr6:30587742 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.265C>T (p.Arg89Trp) single nucleotide variant Inborn genetic diseases [RCV002830369] Chr6:30619786 [GRCh38]
Chr6:30587563 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.319A>G (p.Ile107Val) single nucleotide variant Inborn genetic diseases [RCV002708506] Chr6:30619954 [GRCh38]
Chr6:30587731 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.65C>T (p.Ser22Phe) single nucleotide variant Inborn genetic diseases [RCV002940402] Chr6:30617930 [GRCh38]
Chr6:30585707 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.286C>T (p.Arg96Cys) single nucleotide variant Inborn genetic diseases [RCV002935999] Chr6:30619921 [GRCh38]
Chr6:30587698 [GRCh37]
Chr6:6p21.33
uncertain significance
NM_014046.4(MRPS18B):c.392C>T (p.Thr131Met) single nucleotide variant Inborn genetic diseases [RCV003366176] Chr6:30622869 [GRCh38]
Chr6:30590646 [GRCh37]
Chr6:6p21.33
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1394
Count of miRNA genes:629
Interacting mature miRNAs:705
Transcripts:ENST00000259873, ENST00000472229, ENST00000472267, ENST00000492316, ENST00000506373
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH102456  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,593,987 - 30,594,116UniSTSGRCh37
Build 36630,701,966 - 30,702,095RGDNCBI36
Celera632,192,105 - 32,192,234RGD
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map6p21.33UniSTS
HuRef630,394,155 - 30,394,284UniSTS
GeneMap99-GB4 RH Map6118.72UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1
Medium 2439 2684 1723 622 1687 463 4357 2154 3673 417 1459 1612 175 1 1204 2788 6 2
Low 307 3 2 264 2 43 61 2 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_014046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054355242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB110933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB110934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB202094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF100761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL050361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE220785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG773408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP369345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX119957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX248507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX908728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR753328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000259873   ⟹   ENSP00000259873
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl630,617,840 - 30,626,392 (+)Ensembl
RefSeq Acc Id: ENST00000472229
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl630,617,860 - 30,626,395 (+)Ensembl
RefSeq Acc Id: ENST00000472267
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl630,617,852 - 30,626,395 (+)Ensembl
RefSeq Acc Id: ENST00000492316
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl630,617,843 - 30,620,124 (+)Ensembl
RefSeq Acc Id: NM_014046   ⟹   NP_054765
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,617,840 - 30,626,392 (+)NCBI
GRCh37630,585,275 - 30,594,174 (+)NCBI
Build 36630,693,585 - 30,702,148 (+)NCBI Archive
Celera632,183,604 - 32,192,292 (+)RGD
HuRef630,385,654 - 30,394,342 (+)RGD
CHM1_1630,587,595 - 30,596,284 (+)NCBI
T2T-CHM13v2.0630,482,021 - 30,490,573 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024446408   ⟹   XP_024302176
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,617,840 - 30,626,392 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054355242   ⟹   XP_054211217
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0630,482,021 - 30,490,573 (+)NCBI
Protein Sequences
Protein RefSeqs NP_054765 (Get FASTA)   NCBI Sequence Viewer  
  XP_024302176 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185773 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186261 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186552 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186778 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187293 (Get FASTA)   NCBI Sequence Viewer  
  XP_054211217 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD43025 (Get FASTA)   NCBI Sequence Viewer  
  AAF36103 (Get FASTA)   NCBI Sequence Viewer  
  AAH05373 (Get FASTA)   NCBI Sequence Viewer  
  AQY76936 (Get FASTA)   NCBI Sequence Viewer  
  AQY76937 (Get FASTA)   NCBI Sequence Viewer  
  BAD13699 (Get FASTA)   NCBI Sequence Viewer  
  BAD13700 (Get FASTA)   NCBI Sequence Viewer  
  BAE78614 (Get FASTA)   NCBI Sequence Viewer  
  BAG34831 (Get FASTA)   NCBI Sequence Viewer  
  BAG57427 (Get FASTA)   NCBI Sequence Viewer  
  CAH56415 (Get FASTA)   NCBI Sequence Viewer  
  EAX03304 (Get FASTA)   NCBI Sequence Viewer  
  EAX03305 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000259873
  ENSP00000259873.4
  ENSP00000383437.3
  ENSP00000383438.3
  ENSP00000390930.2
  ENSP00000397340.2
  ENSP00000397472.2
  ENSP00000397790.2
  ENSP00000398494.2
  ENSP00000398549.2
  ENSP00000398781.2
  ENSP00000402718.2
  ENSP00000414972.2
  ENSP00000415703.2
GenBank Protein Q9Y676 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_054765   ⟸   NM_014046
- UniProtKB: Q659G4 (UniProtKB/Swiss-Prot),   A6NDQ0 (UniProtKB/Swiss-Prot),   Q9BS27 (UniProtKB/Swiss-Prot),   Q9Y676 (UniProtKB/Swiss-Prot),   B0S7P4 (UniProtKB/TrEMBL),   A0A1U9X819 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024302176   ⟸   XM_024446408
- Peptide Label: isoform X1
- UniProtKB: B4DFG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000259873   ⟸   ENST00000259873
RefSeq Acc Id: XP_054211217   ⟸   XM_054355242
- Peptide Label: isoform X1
- UniProtKB: B4DFG6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y676-F1-model_v2 AlphaFold Q9Y676 1-258 view protein structure

Promoters
RGD ID:6872396
Promoter ID:EPDNEW_H9363
Type:initiation region
Name:MRPS18B_1
Description:mitochondrial ribosomal protein S18B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,617,840 - 30,617,900EPDNEW
RGD ID:6803900
Promoter ID:HG_KWN:52837
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000396492,   NM_014046,   OTTHUMT00000076556,   OTTHUMT00000076583,   OTTHUMT00000076585,   OTTHUMT00000256174,   OTTHUMT00000256239,   UC010JSC.1,   UC010JSD.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,692,981 - 30,693,667 (-)MPROMDB
RGD ID:6852776
Promoter ID:EP74203
Type:multiple initiation site
Name:HS_MRPS18B
Description:Mitochondrial ribosomal protein S18B.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,693,612 - 30,693,672EPD

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14516 AgrOrtholog
COSMIC MRPS18B COSMIC
Ensembl Genes ENSG00000203624 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000204568 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000223775 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000226111 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000227420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000229861 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000233813 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000259873 ENTREZGENE
  ENST00000259873.5 UniProtKB/Swiss-Prot
  ENST00000327800.10 UniProtKB/Swiss-Prot
  ENST00000400594.3 UniProtKB/TrEMBL
  ENST00000412451.6 UniProtKB/Swiss-Prot
  ENST00000412843.2 UniProtKB/TrEMBL
  ENST00000418070.2 UniProtKB/TrEMBL
  ENST00000426945.6 UniProtKB/Swiss-Prot
  ENST00000428224.2 UniProtKB/TrEMBL
  ENST00000430402.6 UniProtKB/Swiss-Prot
  ENST00000437247.2 UniProtKB/TrEMBL
  ENST00000440992.2 UniProtKB/TrEMBL
  ENST00000451032.6 UniProtKB/Swiss-Prot
  ENST00000454427.6 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.640.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000203624 GTEx
  ENSG00000204568 GTEx
  ENSG00000223775 GTEx
  ENSG00000226111 GTEx
  ENSG00000227420 GTEx
  ENSG00000229861 GTEx
  ENSG00000233813 GTEx
HGNC ID HGNC:14516 ENTREZGENE
Human Proteome Map MRPS18B Human Proteome Map
InterPro MRPS18B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S18_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:28973 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 28973 ENTREZGENE
OMIM 611982 OMIM
PANTHER 28S RIBOSOMAL PROTEIN S18B, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13329 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_S18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA31004 PharmGKB
Superfamily-SCOP Ribosomal_S18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JIC6_HUMAN UniProtKB/TrEMBL
  A0A1U9X819 ENTREZGENE, UniProtKB/TrEMBL
  A6NDQ0 ENTREZGENE
  B0S7P4 ENTREZGENE, UniProtKB/TrEMBL
  B4DFG6 ENTREZGENE, UniProtKB/TrEMBL
  Q659G4 ENTREZGENE
  Q9BS27 ENTREZGENE
  Q9Y676 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A6NDQ0 UniProtKB/Swiss-Prot
  Q659G4 UniProtKB/Swiss-Prot
  Q9BS27 UniProtKB/Swiss-Prot