MRPS18B (mitochondrial ribosomal protein S18B) - Rat Genome Database

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Gene: MRPS18B (mitochondrial ribosomal protein S18B) Canis lupus familiaris
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Symbol: MRPS18B
Name: mitochondrial ribosomal protein S18B
RGD ID: 12114038
Description: ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN mitochondrial translation (inferred); translation (inferred); ASSOCIATED WITH Disease Progression (ortholog); genetic disease (ortholog); megacolon (ortholog); FOUND IN cell junction (inferred); mitochondrial small ribosomal subunit (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 28S ribosomal protein S18b, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112435,117 - 441,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12435,180 - 441,161 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12572,758 - 579,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.012579,258 - 585,768 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12579,317 - 585,764 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112435,808 - 442,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012505,092 - 511,380 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012574,914 - 581,424 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MRPS18B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112435,117 - 441,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12435,180 - 441,161 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12572,758 - 579,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.012579,258 - 585,768 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12579,317 - 585,764 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112435,808 - 442,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012505,092 - 511,380 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012574,914 - 581,424 (+)NCBIUU_Cfam_GSD_1.0
MRPS18B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,617,840 - 30,626,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,617,840 - 30,626,395 (+)EnsemblGRCh38hg38GRCh38
GRCh37630,585,617 - 30,594,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,693,585 - 30,702,148 (+)NCBINCBI36Build 36hg18NCBI36
Build 34630,693,584 - 30,702,146NCBI
Celera632,183,604 - 32,192,292 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef630,385,654 - 30,394,342 (+)NCBIHuRef
CHM1_1630,587,595 - 30,596,284 (+)NCBICHM1_1
T2T-CHM13v2.0630,482,021 - 30,490,573 (+)NCBIT2T-CHM13v2.0
Mrps18b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,221,272 - 36,227,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,221,271 - 36,227,281 (-)EnsemblGRCm39 Ensembl
GRCm381735,910,380 - 35,916,440 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,910,379 - 35,916,389 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,047,330 - 36,053,314 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,518,438 - 35,524,422 (-)NCBIMGSCv36mm8
Celera1739,419,647 - 39,425,606 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.76NCBI
Mrps18b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8202,842,978 - 2,849,065 (+)NCBIGRCr8
mRatBN7.2202,838,174 - 2,844,260 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,838,030 - 2,844,260 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,889,984 - 2,896,037 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0202,894,954 - 2,901,007 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0202,921,099 - 2,927,165 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,344,870 - 3,350,929 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,344,870 - 3,350,927 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,442,393 - 5,448,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4202,985,972 - 2,992,031 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1202,986,225 - 2,992,253 (+)NCBI
Celera20264,183 - 270,242 (+)NCBICelera
Cytogenetic Map20p12NCBI
Mrps18b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583635,697 - 641,885 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955583635,697 - 641,885 (+)NCBIChiLan1.0ChiLan1.0
MRPS18B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,175,270 - 45,184,206 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,138,461 - 41,147,399 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,360,136 - 30,368,735 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,230,124 - 31,237,970 (+)NCBIpanpan1.1PanPan1.1panPan2
Mrps18b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494633,928,495 - 33,934,850 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936837294,654 - 299,857 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936837293,792 - 300,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPS18B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,165,946 - 23,172,998 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,166,314 - 23,172,718 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2726,835,923 - 26,842,328 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRPS18B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11741,830,763 - 41,839,026 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604430,310,936 - 30,320,525 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrps18b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,069,854 - 25,076,104 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,069,857 - 25,076,044 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MRPS18B
81 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000000648   ⟹   ENSCAFP00000000593
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl12435,180 - 441,161 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012826   ⟹   ENSCAFP00845009996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl12579,317 - 585,764 (+)Ensembl
RefSeq Acc Id: XM_038491258   ⟹   XP_038347186
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.112435,808 - 442,103 (+)NCBI
RefSeq Acc Id: XM_038553432   ⟹   XP_038409360
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.012574,914 - 581,424 (+)NCBI
RefSeq Acc Id: XM_038617317   ⟹   XP_038473245
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.012505,092 - 511,380 (+)NCBI
RefSeq Acc Id: XM_038682916   ⟹   XP_038538844
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.012579,258 - 585,768 (+)NCBI
RefSeq Acc Id: XM_532057   ⟹   XP_532057
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.112435,117 - 441,406 (+)NCBI
Dog10K_Boxer_Tasha12572,758 - 579,049 (+)NCBI
Sequence:
RefSeq Acc Id: XP_532057   ⟸   XM_532057
- UniProtKB: A0A8C0KZM9 (UniProtKB/TrEMBL),   A0A8C0YYK3 (UniProtKB/TrEMBL),   A0A8I3N171 (UniProtKB/TrEMBL),   A0A8C0RF48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000000593   ⟸   ENSCAFT00000000648
RefSeq Acc Id: XP_038347186   ⟸   XM_038491258
RefSeq Acc Id: XP_038473245   ⟸   XM_038617317
RefSeq Acc Id: XP_038538844   ⟸   XM_038682916
- UniProtKB: A0A8C0KZM9 (UniProtKB/TrEMBL),   A0A8C0YYK3 (UniProtKB/TrEMBL),   A0A8I3N171 (UniProtKB/TrEMBL),   A0A8C0RF48 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038409360   ⟸   XM_038553432
- UniProtKB: A0A8C0KZM9 (UniProtKB/TrEMBL),   A0A8C0RF48 (UniProtKB/TrEMBL),   A0A8C0YYK3 (UniProtKB/TrEMBL),   A0A8I3N171 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845009996   ⟸   ENSCAFT00845012826

Promoters
RGD ID:13685324
Promoter ID:EPDNEW_C3393
Type:multiple initiation site
Name:MRPS18B_1
Description:mitochondrial ribosomal protein S18B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.112435,184 - 435,244EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000411 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030007813 UniProtKB/TrEMBL
  ENSCAFG00040014781 UniProtKB/TrEMBL
  ENSCAFG00845007249 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000000648.5 UniProtKB/TrEMBL
  ENSCAFT00030014339.1 UniProtKB/TrEMBL
  ENSCAFT00040027238.1 UniProtKB/TrEMBL
  ENSCAFT00845012826 ENTREZGENE
  ENSCAFT00845012826.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.640.10 UniProtKB/TrEMBL
InterPro MRPS18B UniProtKB/TrEMBL
  Ribosomal_S18 UniProtKB/TrEMBL
  Ribosomal_S18_sf UniProtKB/TrEMBL
KEGG Report cfa:474827 UniProtKB/TrEMBL
NCBI Gene MRPS18B ENTREZGENE
PANTHER 28S RIBOSOMAL PROTEIN S18B, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR13329 UniProtKB/TrEMBL
Pfam Ribosomal_S18 UniProtKB/TrEMBL
Superfamily-SCOP SSF46911 UniProtKB/TrEMBL
UniProt A0A8C0KZM9 ENTREZGENE
  A0A8C0RF48 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0YYK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N171 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43413 ENTREZGENE