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Gene: CBY1 (chibby family member 1, beta catenin antagonist) Homo sapiens
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Symbol: CBY1
Name: chibby family member 1, beta catenin antagonist
Description: Exhibits beta-catenin binding activity and protein homodimerization activity. Involved in several processes, including negative regulation of Wnt signaling pathway; negative regulation of transcription, DNA-templated; and protein homotetramerization. Localizes to centriole; nucleus; and trans-Golgi network.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: arb1; ARPP-binding protein; C22orf2; CBY; chibby CTNNB1-mediated transcription inhibitor; chibby homolog 1; chibby homolog 1 (Drosophila); Chibby1; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; HS508I15A; PGEA1; PIGEA-14; PIGEA14; PKD2 interactor, golgi and endoplasmic reticulum associated 1; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa
Orthologs:
Mus musculus (house mouse) : Cby1 (chibby family member 1, beta catenin antagonist)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cby1 (chibby family member 1, beta catenin antagonist)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cby1 (chibby family member 1, beta catenin antagonist)
Pan paniscus (bonobo/pygmy chimpanzee) : CBY1 (chibby family member 1, beta catenin antagonist)
Canis lupus familiaris (dog) : CBY1 (chibby family member 1, beta catenin antagonist)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cby1 (chibby family member 1, beta catenin antagonist)
Sus scrofa (pig) : CBY1 (chibby family member 1, beta catenin antagonist)
Chlorocebus sabaeus (African green monkey) : CBY1 (chibby family member 1, beta catenin antagonist)
Heterocephalus glaber (naked mole-rat) : Cby1 (chibby family member 1, beta catenin antagonist)
more info ...
Related Pseudogenes: CBY1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2238,656,636 - 38,673,854 (+)EnsemblGRCh38hg38GRCh38
GRCh382238,656,653 - 38,673,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372239,052,658 - 39,069,859 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,382,604 - 37,399,801 (+)NCBINCBI36hg18NCBI36
Build 342237,377,157 - 37,394,353NCBI
Celera2222,859,330 - 22,876,528 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2222,018,745 - 22,036,064 (+)NCBIHuRef
CHM1_12239,011,535 - 39,028,742 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CBY1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343969
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.