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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343969
Species: Homo sapiens
RGD Object: Gene
Symbol: CBY1
Name: chibby 1, beta catenin antagonist
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CBY1decreases expressionISOCby1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CBY1 mRNAPMID:21215274
CBY1decreases phosphorylationISOCby1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased phosphorylation of CBY1 proteinPMID:23298284
CBY1increases expressionISOCby1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CBY1 mRNAPMID:33387578
CBY1multiple interactionsISOCby1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CBY1 mRNAPMID:17942748
CBY1multiple interactionsISOCby1 (Rattus norvegicus)6480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CBY1 mRNA]PMID:21215274
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