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Gene: Setd5 (SET domain containing 5) Mus musculus
Symbol: Setd5
Name: SET domain containing 5
Description: Exhibits histone methyltransferase activity (H3-K9 specific). Involved in covalent chromatin modification and regulation of histone acetylation. Localizes to the nucleus. Colocalizes with the Cdc73/Paf1 complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 23. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SETD5 (SET domain containing 5); INTERACTS WITH 4-hydroxyphenyl retinamide; aflatoxin B1; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900045N06Rik; C330007C20; C85544; FLJ10707; histone-lysine N-methyltransferase SETD5; MGC90828; mKIAA1757; SET domain-containing protein 5
Homo sapiens (human) : SETD5 (SET domain containing 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Setd5 (SET domain containing 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Setd5 (SET domain containing 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SETD5 (SET domain containing 5)
Canis lupus familiaris (dog) : SETD5 (SET domain containing 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Setd5 (SET domain containing 5)
Sus scrofa (pig) : SETD5 (SET domain containing 5)
Chlorocebus sabaeus (green monkey) : SETD5 (SET domain containing 5)
Heterocephalus glaber (naked mole-rat) : Setd5 (SET domain containing 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6113,077,365 - 113,153,435 (+)Ensembl
GRCm386113,077,262 - 113,153,432 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376113,027,633 - 113,103,418 (+)NCBIGRCm37mm9NCBIm37
MGSCv366113,043,416 - 113,119,201 (+)NCBImm8
Celera6114,906,553 - 114,982,234 (+)NCBICelera
Cytogenetic Map6 E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Setd5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321331
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.