RPP40 (ribonuclease P/MRP subunit p40) - Rat Genome Database

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Gene: RPP40 (ribonuclease P/MRP subunit p40) Homo sapiens
Analyze
Symbol: RPP40
Name: ribonuclease P/MRP subunit p40
RGD ID: 1321008
HGNC Page HGNC:20992
Description: Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Part of multimeric ribonuclease P complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bA428J1.3; ribonuclease P (40 kD); ribonuclease P 40kDa subunit; ribonuclease P protein subunit p40; ribonuclease P, 40kD subunit; ribonuclease P/MRP 40kDa subunit; ribonuclease P1; RNase P subunit 1; RNaseP protein p40; RNASEP1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: RPP40P1   RPP40P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3864,988,426 - 5,004,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl64,994,717 - 5,004,063 (-)EnsemblGRCh38hg38GRCh38
GRCh3764,994,951 - 5,004,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3664,940,279 - 4,949,270 (-)NCBINCBI36Build 36hg18NCBI36
Build 3464,940,279 - 4,949,270NCBI
Celera66,224,004 - 6,232,997 (-)NCBICelera
Cytogenetic Map6p25.1NCBI
HuRef64,871,613 - 4,880,606 (-)NCBIHuRef
CHM1_164,997,633 - 5,006,608 (-)NCBICHM1_1
T2T-CHM13v2.064,855,789 - 4,873,023 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 68 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RPP40Human(1->4)-beta-D-glucan multiple interactionsISORpp40 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RPP40 mRNACTDPMID:36331819
RPP40Human17alpha-ethynylestradiol affects expressionISORpp40 (Mus musculus)6480464Ethinyl Estradiol affects the expression of RPP40 mRNACTDPMID:17555576
RPP40Human17alpha-ethynylestradiol increases expressionISORpp40 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of RPP40 mRNACTDPMID:17942748
RPP40Human17alpha-ethynylestradiol multiple interactionsISORpp40 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPP40 mRNACTDPMID:17942748
RPP40Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of RPP40 mRNACTDPMID:31614463
RPP40Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORpp40 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPP40 mRNACTDPMID:17942748
RPP40Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORpp40 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in increased expression of RPP40 mRNACTDPMID:33387578
RPP40Human2,4-dinitrotoluene affects expressionISORpp40 (Rattus norvegicus)64804642 and 4-dinitrotoluene affects the expression of RPP40 mRNACTDPMID:21346803
RPP40Human2,6-dinitrotoluene affects expressionISORpp40 (Rattus norvegicus)64804642 and 6-dinitrotoluene affects the expression of RPP40 mRNACTDPMID:21346803
RPP40Human2-methylcholine affects expressionEXP 6480464beta-methylcholine affects the expression of RPP40 mRNACTDPMID:21179406
RPP40Human4,4'-diaminodiphenylmethane decreases expressionISORpp40 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of RPP40 mRNACTDPMID:18648102
RPP40Human4,4'-sulfonyldiphenol increases expressionISORpp40 (Mus musculus)6480464bisphenol S results in increased expression of RPP40 mRNACTDPMID:39298647
RPP40Humanall-trans-retinoic acid decreases expressionEXP 6480464Tretinoin results in decreased expression of RPP40 mRNACTDPMID:21934132 and PMID:33167477
RPP40Humanarsane multiple interactionsEXP 6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of RPP40 mRNACTDPMID:39836092
RPP40Humanarsenic atom multiple interactionsEXP 6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of RPP40 mRNACTDPMID:39836092
RPP40HumanBenoxacor increases expressionISORpp40 (Mus musculus)6480464benoxacor results in increased expression of RPP40 mRNACTDPMID:34850242
RPP40Humanbisphenol A increases expressionISORpp40 (Mus musculus)6480464bisphenol A results in increased expression of RPP40 mRNACTDPMID:26063408
RPP40Humanbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with Fulvestrant] results in decreased methylation of RPP40 geneCTDPMID:31601247
RPP40Humanbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of RPP40 proteinCTDPMID:33376534
RPP40Humanbisphenol A decreases methylationEXP 6480464bisphenol A results in decreased methylation of RPP40 geneCTDPMID:31601247

1 to 20 of 68 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RPP40Humanendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) involved_inIBAPANTHER:PTN001034909 and PomBase:SPAC6C3.09150520179 GO_CentralGO_REF:0000033
RPP40HumanrRNA processing involved_inIEAUniProtKB-KW:KW-0698150520179 UniProtGO_REF:0000043
RPP40HumantRNA 5'-leader removal involved_inIEAInterPro:IPR013893150520179 InterProGO_REF:0000002
RPP40HumantRNA 5'-leader removal involved_inIBAPANTHER:PTN001034909 and UniProtKB:O75818150520179 GO_CentralGO_REF:0000033
RPP40HumantRNA 5'-leader removal involved_inIDA 150520179 PMID:30454648UniProtPMID:30454648
RPP40HumantRNA processing involved_inIEAUniProtKB-KW:KW-0819150520179 UniProtGO_REF:0000043

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RPP40Humanmultimeric ribonuclease P complex part_ofIDA 150520179 PMID:30454648UniProtPMID:30454648
RPP40Humanmultimeric ribonuclease P complex part_ofIBAPANTHER:PTN001034909 and UniProtKB:O75818150520179 GO_CentralGO_REF:0000033
RPP40Humannucleolar ribonuclease P complex part_ofTAS 150520179 PMID:9630247PINCPMID:9630247
RPP40Humannucleolus located_inIEAUniProtKB-SubCell:SL-0188150520179 UniProtGO_REF:0000044
RPP40Humannucleoplasm located_inTAS 150520179 ReactomeReactome:R-HSA-5696810 and Reactome:R-HSA-6791223
RPP40Humannucleus located_inTAS 150520179 PMID:9630247PINCPMID:9630247
RPP40Humannucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
RPP40Humanribonuclease MRP complex part_ofIBAPANTHER:PTN001034909 and PomBase:SPAC6C3.09150520179 GO_CentralGO_REF:0000033
RPP40Humanribonuclease P complex part_ofIEAInterPro:IPR013893150520179 InterProGO_REF:0000002
1 to 9 of 9 rows

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RPP40HumantRNA maturation pathway  TAS 9685326 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RPP40Humanribosome biogenesis pathway   IEA 6907045 KEGGhsa:03008

#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Unexpected diversity of RNase P, an ancient tRNA processing enzyme: challenges and prospects. Lai LB, etal., FEBS Lett. 2010 Jan 21;584(2):287-96. doi: 10.1016/j.febslet.2009.11.048. Epub .
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8889548   PMID:9630247   PMID:12477932   PMID:15096576   PMID:16341674   PMID:19460752   PMID:21053045   PMID:21081503   PMID:21873635   PMID:22863883   PMID:22939629   PMID:26186194  
PMID:26472758   PMID:28514442   PMID:28515276   PMID:29395067   PMID:29509190   PMID:30454648   PMID:31091453   PMID:31527615   PMID:31665637   PMID:31685992   PMID:32296183   PMID:32807901  
PMID:33961781   PMID:34079125   PMID:34373451   PMID:35271311   PMID:35831314   PMID:35850772   PMID:35944360   PMID:36215168   PMID:37267103   PMID:37536630   PMID:37866880  



RPP40
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3864,988,426 - 5,004,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl64,994,717 - 5,004,063 (-)EnsemblGRCh38hg38GRCh38
GRCh3764,994,951 - 5,004,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3664,940,279 - 4,949,270 (-)NCBINCBI36Build 36hg18NCBI36
Build 3464,940,279 - 4,949,270NCBI
Celera66,224,004 - 6,232,997 (-)NCBICelera
Cytogenetic Map6p25.1NCBI
HuRef64,871,613 - 4,880,606 (-)NCBIHuRef
CHM1_164,997,633 - 5,006,608 (-)NCBICHM1_1
T2T-CHM13v2.064,855,789 - 4,873,023 (-)NCBIT2T-CHM13v2.0
Rpp40
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391336,080,685 - 36,095,548 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1336,077,455 - 36,090,342 (-)EnsemblGRCm39 Ensembl
GRCm381335,895,104 - 35,911,565 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1335,893,472 - 35,906,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv371335,986,973 - 35,998,216 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361335,900,937 - 35,913,812 (-)NCBIMGSCv36mm8
Celera1337,009,759 - 37,021,002 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.44NCBI
Rpp40
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81729,153,203 - 29,162,241 (+)NCBIGRCr8
mRatBN7.21728,947,752 - 28,956,788 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1728,947,734 - 28,956,788 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1728,807,889 - 28,816,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01730,411,435 - 30,420,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01728,783,409 - 28,792,437 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01729,638,647 - 29,647,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1729,638,677 - 29,647,763 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01731,534,547 - 31,543,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41735,249,263 - 35,257,891 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11735,252,103 - 35,260,731 (+)NCBI
Celera1728,549,277 - 28,557,686 (+)NCBICelera
Cytogenetic Map17p12NCBI
Rpp40
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554658,540,459 - 8,550,249 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554658,540,500 - 8,550,255 (+)NCBIChiLan1.0ChiLan1.0
RPP40
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2519,623,806 - 19,632,422 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1615,627,775 - 15,636,370 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v064,828,155 - 4,838,680 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.165,015,953 - 5,024,540 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl65,015,953 - 5,024,540 (-)Ensemblpanpan1.1panPan2
RPP40
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1355,109,324 - 5,119,713 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl355,109,658 - 5,120,294 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,118,469 - 5,128,320 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0355,181,170 - 5,191,232 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl355,181,173 - 5,191,799 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1355,046,009 - 5,056,067 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0355,071,013 - 5,081,115 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0356,403,016 - 6,413,078 (-)NCBIUU_Cfam_GSD_1.0
Rpp40
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494619,202,211 - 19,211,477 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365347,471,198 - 7,480,475 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365347,471,209 - 7,480,457 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPP40
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl72,987,271 - 3,005,271 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.172,990,405 - 3,042,423 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RPP40
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11767,172,759 - 67,181,669 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1767,173,130 - 67,181,975 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660444,945,666 - 4,954,176 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpp40
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475620,233,664 - 20,243,598 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475620,233,659 - 20,242,733 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in RPP40
27 total Variants

1 to 10 of 80 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 6p25.3-25.1(chr6:163083-6062800)x1 copy number loss See cases [RCV000050686] Chr6:163083..6062800 [GRCh38]
Chr6:163083..6063033 [GRCh37]
Chr6:108083..6008032 [NCBI36]
Chr6:6p25.3-25.1
pathogenic
GRCh38/hg38 6p25.3-23(chr6:389423-13474956)x3 copy number gain See cases [RCV000051896] Chr6:389423..13474956 [GRCh38]
Chr6:389423..13475188 [GRCh37]
Chr6:334423..13583167 [NCBI36]
Chr6:6p25.3-23
pathogenic
GRCh38/hg38 6p25.3-22.3(chr6:106431-18360595)x3 copy number gain See cases [RCV000051869] Chr6:106431..18360595 [GRCh38]
Chr6:106431..18360826 [GRCh37]
Chr6:51431..18468805 [NCBI36]
Chr6:6p25.3-22.3
pathogenic
GRCh38/hg38 6p25.3-25.1(chr6:144957-5239181)x3 copy number gain See cases [RCV000051870] Chr6:144957..5239181 [GRCh38]
Chr6:144957..5239414 [GRCh37]
Chr6:89957..5184413 [NCBI36]
Chr6:6p25.3-25.1
pathogenic
GRCh38/hg38 6p25.3-25.1(chr6:162883-5979198)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052160]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052160]|See cases [RCV000052160] Chr6:162883..5979198 [GRCh38]
Chr6:162883..5979431 [GRCh37]
Chr6:107883..5924430 [NCBI36]
Chr6:6p25.3-25.1
pathogenic
GRCh38/hg38 6p25.3-25.1(chr6:163083-5875402)x1 copy number loss See cases [RCV000052161] Chr6:163083..5875402 [GRCh38]
Chr6:163083..5875635 [GRCh37]
Chr6:108083..5820634 [NCBI36]
Chr6:6p25.3-25.1
pathogenic
GRCh38/hg38 6p25.3-25.1(chr6:164633-6284237)x1 copy number loss See cases [RCV000052163] Chr6:164633..6284237 [GRCh38]
Chr6:164633..6284470 [GRCh37]
Chr6:109633..6229469 [NCBI36]
Chr6:6p25.3-25.1
pathogenic
GRCh38/hg38 6p25.3-25.1(chr6:164633-5823601)x1 copy number loss See cases [RCV000052164] Chr6:164633..5823601 [GRCh38]
Chr6:164633..5823834 [GRCh37]
Chr6:109633..5768833 [NCBI36]
Chr6:6p25.3-25.1
pathogenic
GRCh38/hg38 6p25.3-24.3(chr6:165675-9036034)x1 copy number loss See cases [RCV000052165] Chr6:165675..9036034 [GRCh38]
Chr6:165675..9036267 [GRCh37]
Chr6:110675..8981266 [NCBI36]
Chr6:6p25.3-24.3
pathogenic
GRCh38/hg38 6p25.1-24.3(chr6:4427090-8391140)x1 copy number loss See cases [RCV000052177] Chr6:4427090..8391140 [GRCh38]
Chr6:4427324..8391373 [GRCh37]
Chr6:4372323..8336372 [NCBI36]
Chr6:6p25.1-24.3
pathogenic
1 to 10 of 80 rows

Predicted Target Of
Summary Value
Count of predictions:789
Count of miRNA genes:484
Interacting mature miRNAs:524
Transcripts:ENST00000319533, ENST00000380051, ENST00000464646, ENST00000468105, ENST00000479782, ENST00000483546
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597133668GWAS1229742_Hmemory performance QTL GWAS1229742 (human)0.000004memory performance649955744995575Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
596986908GWAS1106427_Hmemory performance QTL GWAS1106427 (human)0.000004memory performance649955744995575Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
1643495BW291_HBody Weight QTL 291 (human)2.13Body weightBMI6119321359Human

RH47442  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3764,995,339 - 4,995,479UniSTSGRCh37
Build 3664,940,338 - 4,940,478RGDNCBI36
Celera66,224,063 - 6,224,203RGD
Cytogenetic Map6p25.1UniSTS
HuRef64,871,672 - 4,871,812UniSTS
GeneMap99-GB4 RH Map625.31UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1940 465 2270 7295 6461 53 3734 1 852 1744 1617 174 1


1 to 28 of 28 rows
RefSeq Transcripts NM_001286132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007059200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008487242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008487243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_926031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL359643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG430780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM015573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM827175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ220155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU607286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX951376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF583869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 28 of 28 rows

Ensembl Acc Id: ENST00000319533   ⟹   ENSP00000317998
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl64,995,047 - 5,004,036 (-)Ensembl
Ensembl Acc Id: ENST00000380051   ⟹   ENSP00000369391
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl64,994,717 - 5,004,037 (-)Ensembl
Ensembl Acc Id: ENST00000464646   ⟹   ENSP00000419431
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl64,995,078 - 5,003,658 (-)Ensembl
Ensembl Acc Id: ENST00000468105
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl64,998,688 - 5,004,047 (-)Ensembl
Ensembl Acc Id: ENST00000479782   ⟹   ENSP00000418874
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl64,998,828 - 5,004,018 (-)Ensembl
Ensembl Acc Id: ENST00000483546
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl65,001,776 - 5,004,063 (-)Ensembl
Ensembl Acc Id: ENST00000618533   ⟹   ENSP00000484334
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl64,995,049 - 5,004,063 (-)Ensembl
RefSeq Acc Id: NM_001286132   ⟹   NP_001273061
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,994,717 - 5,004,037 (-)NCBI
HuRef64,871,613 - 4,880,632 (-)NCBI
CHM1_164,997,633 - 5,006,634 (-)NCBI
T2T-CHM13v2.064,863,716 - 4,873,023 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286133   ⟹   NP_001273062
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,994,717 - 5,004,037 (-)NCBI
HuRef64,871,613 - 4,880,632 (-)NCBI
CHM1_164,997,633 - 5,006,634 (-)NCBI
T2T-CHM13v2.064,863,716 - 4,873,023 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006638   ⟹   NP_006629
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,994,717 - 5,004,037 (-)NCBI
GRCh3764,995,280 - 5,004,292 (-)NCBI
Build 3664,940,279 - 4,949,270 (-)NCBI Archive
Celera66,224,004 - 6,232,997 (-)RGD
HuRef64,871,613 - 4,880,632 (-)NCBI
CHM1_164,997,633 - 5,006,634 (-)NCBI
T2T-CHM13v2.064,863,716 - 4,873,023 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011514253   ⟹   XP_011512555
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,988,426 - 5,004,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024446309   ⟹   XP_024302077
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,988,426 - 5,004,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047418095   ⟹   XP_047274051
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,994,717 - 5,004,037 (-)NCBI
RefSeq Acc Id: XM_047418096   ⟹   XP_047274052
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,988,426 - 5,004,037 (-)NCBI
RefSeq Acc Id: XM_054354062   ⟹   XP_054210037
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.064,862,553 - 4,873,023 (-)NCBI
RefSeq Acc Id: XM_054354063   ⟹   XP_054210038
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.064,863,716 - 4,873,023 (-)NCBI
RefSeq Acc Id: XM_054354064   ⟹   XP_054210039
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.064,862,553 - 4,873,023 (-)NCBI
RefSeq Acc Id: XM_054354065   ⟹   XP_054210040
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.064,862,553 - 4,873,023 (-)NCBI
RefSeq Acc Id: XR_007059200
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,988,426 - 5,004,037 (-)NCBI
RefSeq Acc Id: XR_008487242
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.064,855,791 - 4,873,023 (-)NCBI
RefSeq Acc Id: XR_008487243
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.064,855,789 - 4,873,023 (-)NCBI
RefSeq Acc Id: XR_926031
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3864,988,426 - 5,004,037 (-)NCBI
Sequence:
1 to 5 of 16 rows
1 to 5 of 16 rows
RefSeq Acc Id: NP_006629   ⟸   NM_006638
- Peptide Label: isoform a
- UniProtKB: Q5VX97 (UniProtKB/Swiss-Prot),   Q8WVK8 (UniProtKB/Swiss-Prot),   O75818 (UniProtKB/Swiss-Prot),   X6RLL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273061   ⟸   NM_001286132
- Peptide Label: isoform b
- UniProtKB: X6RLL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273062   ⟸   NM_001286133
- Peptide Label: isoform c
- UniProtKB: A0A087X1N3 (UniProtKB/TrEMBL),   X6RLL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512555   ⟸   XM_011514253
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024302077   ⟸   XM_024446309
- Peptide Label: isoform X4
- Sequence:

Name Modeler Protein Id AA Range Protein Structure
AF-O75818-F1-model_v2 AlphaFold O75818 1-363 view protein structure

RGD ID:6804745
Promoter ID:HG_KWN:52203
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_006638,   UC003MWM.1
Position:
Human AssemblyChrPosition (strand)Source
Build 3664,949,151 - 4,949,651 (-)MPROMDB
RGD ID:6871940
Promoter ID:EPDNEW_H9134
Type:initiation region
Name:RPP40_1
Description:ribonuclease P/MRP subunit p40
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3865,004,027 - 5,004,087EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
COSMIC RPP40 COSMIC
Ensembl Genes ENSG00000124787 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000319533 ENTREZGENE
  ENST00000319533.9 UniProtKB/Swiss-Prot
  ENST00000380051 ENTREZGENE
  ENST00000380051.7 UniProtKB/Swiss-Prot
  ENST00000618533 ENTREZGENE
GTEx ENSG00000124787 GTEx
HGNC ID HGNC:20992 ENTREZGENE
Human Proteome Map RPP40 Human Proteome Map
InterPro RNase_P_Rpp40 UniProtKB/Swiss-Prot
KEGG Report hsa:10799 UniProtKB/Swiss-Prot
NCBI Gene 10799 ENTREZGENE
OMIM 606117 OMIM
PANTHER PTHR15396 UniProtKB/Swiss-Prot
  RIBONUCLEASE P PROTEIN SUBUNIT P40 UniProtKB/Swiss-Prot
Pfam Ribonuc_P_40 UniProtKB/Swiss-Prot
PharmGKB PA134911809 PharmGKB
UniProt A0A087X1N3 ENTREZGENE, UniProtKB/TrEMBL
  F8WC38_HUMAN UniProtKB/TrEMBL
  L8E9F2_HUMAN UniProtKB/TrEMBL
  O75818 ENTREZGENE
  Q5VX97 ENTREZGENE
  Q8WVK8 ENTREZGENE
  RPP40_HUMAN UniProtKB/Swiss-Prot
  X6RLL4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5VX97 UniProtKB/Swiss-Prot
  Q8WVK8 UniProtKB/Swiss-Prot
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-12 RPP40  ribonuclease P/MRP subunit p40    ribonuclease P/MRP 40kDa subunit  Symbol and/or name change 5135510 APPROVED