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Gene: RDH8 (retinol dehydrogenase 8) Homo sapiens
Symbol: RDH8
Name: retinol dehydrogenase 8
Description: This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: photoreceptor outer segment all-trans retinol dehydrogenase; PRRDH; retinol dehydrogenase 8 (all-trans); SDR28C2; short chain dehydrogenase/reductase family 28C member 2; short chain dehydrogenase/reductase family 28C, member 2
Mus musculus (house mouse) : Rdh8 (retinol dehydrogenase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rdh8 (retinol dehydrogenase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rdh8 (retinol dehydrogenase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : RDH8 (retinol dehydrogenase 8)
Canis lupus familiaris (dog) : RDH8 (retinol dehydrogenase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rdh8 (retinol dehydrogenase 8)
Sus scrofa (pig) : RDH8 (retinol dehydrogenase 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381910,013,483 - 10,022,279 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,123,925 - 10,132,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,984,925 - 9,993,954 (+)NCBINCBI36hg18NCBI36
Build 34199,984,924 - 9,993,954NCBI
Celera1910,019,397 - 10,028,442 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,704,402 - 9,713,196 (+)NCBIHuRef
CHM1_11910,123,733 - 10,132,768 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RDH8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319361
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.