Symbol:
RDH8
Name:
retinol dehydrogenase 8
RGD ID:
1319361
HGNC Page
HGNC:14423
Description:
Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Predicted to be involved in retinol metabolic process. Predicted to act upstream of or within visual perception. Predicted to be located in plasma membrane. Predicted to be active in cytosol.
Type:
protein-coding
RefSeq Status:
REVIEWED
Previously known as:
photoreceptor outer segment all-trans retinol dehydrogenase; PRRDH; retinol dehydrogenase 8 (all-trans); SDR28C2; short chain dehydrogenase/reductase family 28C member 2; short chain dehydrogenase/reductase family 28C, member 2
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Rdh8 (retinol dehydrogenase 8) HGNC
Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Rattus norvegicus (Norway rat):
Rdh8 (retinol dehydrogenase 8) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Chinchilla lanigera (long-tailed chinchilla):
Rdh8 (retinol dehydrogenase 8) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
RDH8 (retinol dehydrogenase 8) NCBI
Ortholog
Canis lupus familiaris (dog):
RDH8 (retinol dehydrogenase 8) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rdh8 (retinol dehydrogenase 8) NCBI
Ortholog
Sus scrofa (pig):
RDH8 (retinol dehydrogenase 8) HGNC
Ensembl, NCBI, OMA, OrthoDB, Panther
Chlorocebus sabaeus (green monkey):
RDH8 (retinol dehydrogenase 8) NCBI
Ortholog
Heterocephalus glaber (naked mole-rat):
Rdh8 (retinol dehydrogenase 8) NCBI
Ortholog
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Rdh8 (retinol dehydrogenase 8)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Rdh8 (retinol dehydrogenase 8)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
rdh8b (retinol dehydrogenase 8b)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid|ZFIN)
Danio rerio (zebrafish):
rdh8a (retinol dehydrogenase 8a)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid|ZFIN)
Xenopus tropicalis (tropical clawed frog):
rdh8
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus laevis (African clawed frog):
rdh8.L
Alliance
DIOPT (Xenbase)
Xenopus laevis (African clawed frog):
rdh8.S
Alliance
DIOPT (Xenbase)
Xenopus tropicalis (tropical clawed frog):
rasl11a
Alliance
DIOPT (InParanoid|OrthoInspector|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
XB1000829 [provisional]
Alliance
DIOPT (InParanoid|OrthoInspector|SonicParanoid)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 10,013,483 - 10,022,279 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 10,013,249 - 10,022,279 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 10,124,159 - 10,132,955 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 9,984,925 - 9,993,954 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 9,984,924 - 9,993,954 NCBI Celera 19 10,019,397 - 10,028,442 (+) NCBI Celera Cytogenetic Map 19 p13.2 NCBI HuRef 19 9,704,402 - 9,713,196 (+) NCBI HuRef CHM1_1 19 10,123,733 - 10,132,768 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 10,139,673 - 10,148,469 (+) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
RDH8 Human Autism IAGP RGD:14351810 8554872 ClinVar Annotator: match by term: Autism ClinVar PMID:21681106|PMID:30208311
RDH8 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 10,013,483 - 10,022,279 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 10,013,249 - 10,022,279 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 10,124,159 - 10,132,955 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 9,984,925 - 9,993,954 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 9,984,924 - 9,993,954 NCBI Celera 19 10,019,397 - 10,028,442 (+) NCBI Celera Cytogenetic Map 19 p13.2 NCBI HuRef 19 9,704,402 - 9,713,196 (+) NCBI HuRef CHM1_1 19 10,123,733 - 10,132,768 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 10,139,673 - 10,148,469 (+) NCBI T2T-CHM13v2.0
Rdh8 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 9 20,729,790 - 20,739,354 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 9 20,729,799 - 20,737,413 (+) Ensembl GRCm39 Ensembl GRCm38 9 20,818,494 - 20,828,058 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 9 20,818,503 - 20,826,117 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 9 20,622,948 - 20,630,607 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 9 20,568,906 - 20,576,565 (+) NCBI MGSCv36 mm8 Celera 9 18,087,214 - 18,094,873 (+) NCBI Celera Cytogenetic Map 9 A3 NCBI cM Map 9 7.64 NCBI
Rdh8 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 27,629,380 - 27,636,651 (+) NCBI GRCr8 mRatBN7.2 8 19,353,191 - 19,360,462 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 19,353,191 - 19,360,462 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 23,372,628 - 23,379,896 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 21,670,471 - 21,677,742 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 19,582,880 - 19,590,157 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 21,835,065 - 21,842,374 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 21,835,103 - 21,842,374 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 21,891,192 - 21,898,463 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 19,837,679 - 19,844,950 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 8 20,748,500 - 20,755,674 (+) NCBI Celera Cytogenetic Map 8 q13 NCBI
Rdh8 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955495 1,388,424 - 1,392,552 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955495 1,388,385 - 1,393,209 (+) NCBI ChiLan1.0 ChiLan1.0
RDH8 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 14,932,689 - 14,941,498 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 13,932,907 - 13,941,820 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 19 9,565,918 - 9,575,017 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 10,226,185 - 10,235,114 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 19 10,226,185 - 10,235,114 (+) Ensembl panpan1.1 panPan2
RDH8 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 20 51,029,633 - 51,035,910 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 20 51,029,609 - 51,035,951 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 20 50,896,101 - 50,902,410 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 20 51,551,591 - 51,557,900 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 20 51,551,596 - 51,557,940 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 20 50,759,378 - 50,765,691 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 20 51,186,311 - 51,192,625 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 20 51,427,359 - 51,433,667 (-) NCBI UU_Cfam_GSD_1.0
Rdh8
RDH8 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 2 68,871,707 - 68,877,675 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 2 68,871,707 - 68,878,222 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 2 69,199,776 - 69,206,290 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
RDH8
Rdh8
.
Predicted Target Of
Count of predictions: 1030 Count of miRNA genes: 457 Interacting mature miRNAs: 494 Transcripts: ENST00000171214, ENST00000587782, ENST00000589570, ENST00000591589 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1298499 UAE1_H Urinary albumin excretion QTL 1 (human) 2.73 0.0009 Urinary albumin excretion urine albumin:creatinine ratio (ACR) 19 1 16075902 Human 1643451 SLIPL6_H Serum lipid level QTL 6 (human) 2.19 0.0008 Lipid level 19 1 16075902 Human 1581534 BP76_H Blood pressure QTL 76 (human) 2 0.001 Blood pressure pulse pressure 19 1 16075902 Human 1581535 BP65_H Blood pressure QTL 65 (human) 3.1 0.001 Blood pressure pulse pressure 19 1 16075902 Human 2314591 INSUL4_H Insulin level QTL 4 (human) 3.8 0.000038 Insulin level fasting 19 1 16075902 Human 1298476 BP3_H Blood pressure QTL 3 (human) 2.4 Blood pressure systolic 19 1 16075902 Human
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
786
830
1332
653
1950
502
682
185
456
148
1227
2143
2279
9
1714
316
787
438
39
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000587782 ⟹ ENSP00000465773
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 19 10,020,761 - 10,022,070 (+) Ensembl
Ensembl Acc Id:
ENST00000589570
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 19 10,017,166 - 10,021,088 (+) Ensembl
Ensembl Acc Id:
ENST00000591589 ⟹ ENSP00000466058
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 19 10,013,483 - 10,022,279 (+) Ensembl
Ensembl Acc Id:
ENST00000651512 ⟹ ENSP00000498711
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 19 10,013,249 - 10,022,278 (+) Ensembl
RefSeq Acc Id:
NM_015725 ⟹ NP_056540
RefSeq Status:
REVIEWED
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 19 10,013,483 - 10,022,279 (+) NCBI GRCh37 19 10,123,925 - 10,132,954 (+) ENTREZGENE Build 36 19 9,984,925 - 9,993,954 (+) NCBI Archive HuRef 19 9,704,402 - 9,713,196 (+) ENTREZGENE CHM1_1 19 10,123,733 - 10,132,768 (+) NCBI T2T-CHM13v2.0 19 10,139,673 - 10,148,469 (+) NCBI
Sequence:
AGGGAGGGGATCAACATGGCCGCTGCACCCCGGACTGTGTTGATCTCCGGCTGCTCATCAGGAATTGGTCTGGAACTTGCAGTGCAACTGGCCCATGACCCCAAGAAGCGCTACCAGGTCGTGGCCAC
hide sequence
RefSeq Acc Id:
NP_056540 ⟸ NM_015725
- UniProtKB:
Q9NYR8 (UniProtKB/Swiss-Prot), Q9H838 (UniProtKB/Swiss-Prot), K7ELF7 (UniProtKB/TrEMBL)
- Sequence:
MNGQSQVLPGGGHESREGINMAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQ
hide sequence
Ensembl Acc Id:
ENSP00000498711 ⟸ ENST00000651512
Ensembl Acc Id:
ENSP00000465773 ⟸ ENST00000587782
Ensembl Acc Id:
ENSP00000466058 ⟸ ENST00000591589
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2018-02-13
RDH8
retinol dehydrogenase 8
RDH8
retinol dehydrogenase 8 (all-trans)
Symbol and/or name change
5135510 APPROVED
