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Gene: RDH8 (retinol dehydrogenase 8) Homo sapiens
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Symbol: RDH8
Name: retinol dehydrogenase 8
Description: This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: photoreceptor outer segment all-trans retinol dehydrogenase; PRRDH; retinol dehydrogenase 8 (all-trans); SDR28C2; short chain dehydrogenase/reductase family 28C member 2; short chain dehydrogenase/reductase family 28C, member 2
Orthologs:
Mus musculus (house mouse) : Rdh8 (retinol dehydrogenase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rdh8 (retinol dehydrogenase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rdh8 (retinol dehydrogenase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : RDH8 (retinol dehydrogenase 8)
Canis lupus familiaris (dog) : RDH8 (retinol dehydrogenase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rdh8 (retinol dehydrogenase 8)
Sus scrofa (pig) : RDH8 (retinol dehydrogenase 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,013,483 - 10,022,279 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,123,925 - 10,132,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,984,925 - 9,993,954 (+)NCBINCBI36hg18NCBI36
Build 34199,984,924 - 9,993,954NCBI
Celera1910,019,397 - 10,028,442 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,704,402 - 9,713,196 (+)NCBIHuRef
CHM1_11910,123,733 - 10,132,768 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RDH8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319361
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.