RDH8 (retinol dehydrogenase 8) - Rat Genome Database

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Pathways
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Gene: RDH8 (retinol dehydrogenase 8) Chlorocebus sabaeus
Analyze
Symbol: RDH8
Name: retinol dehydrogenase 8
RGD ID: 18771606
Description: ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cycle metabolic pathway; retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: retinol dehydrogenase 8 (all-trans)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,096,680 - 9,102,770 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607410,969,558 - 10,974,970 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RDH8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,096,680 - 9,102,770 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607410,969,558 - 10,974,970 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RDH8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,013,483 - 10,022,279 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,013,249 - 10,022,279 (+)EnsemblGRCh38hg38GRCh38
GRCh371910,124,159 - 10,132,955 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,984,925 - 9,993,954 (+)NCBINCBI36Build 36hg18NCBI36
Build 34199,984,924 - 9,993,954NCBI
Celera1910,019,397 - 10,028,442 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,704,402 - 9,713,196 (+)NCBIHuRef
CHM1_11910,123,733 - 10,132,768 (+)NCBICHM1_1
T2T-CHM13v2.01910,139,673 - 10,148,469 (+)NCBIT2T-CHM13v2.0
Rdh8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,729,790 - 20,739,354 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,729,799 - 20,737,413 (+)EnsemblGRCm39 Ensembl
GRCm38920,818,494 - 20,828,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,818,503 - 20,826,117 (+)EnsemblGRCm38mm10GRCm38
MGSCv37920,622,948 - 20,630,607 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,568,906 - 20,576,565 (+)NCBIMGSCv36mm8
Celera918,087,214 - 18,094,873 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.64NCBI
Rdh8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,629,380 - 27,636,651 (+)NCBIGRCr8
mRatBN7.2819,353,191 - 19,360,462 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,353,191 - 19,360,462 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,372,628 - 23,379,896 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,670,471 - 21,677,742 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,582,880 - 19,590,157 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,835,065 - 21,842,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,835,103 - 21,842,374 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0821,891,192 - 21,898,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,837,679 - 19,844,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera820,748,500 - 20,755,674 (+)NCBICelera
Cytogenetic Map8q13NCBI
Rdh8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,388,424 - 1,392,552 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,388,385 - 1,393,209 (+)NCBIChiLan1.0ChiLan1.0
RDH8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22014,932,689 - 14,941,498 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11913,932,907 - 13,941,820 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,565,918 - 9,575,017 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,226,185 - 10,235,114 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,226,185 - 10,235,114 (+)Ensemblpanpan1.1panPan2
RDH8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12051,029,633 - 51,035,910 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2051,029,609 - 51,035,951 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,896,101 - 50,902,410 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,551,591 - 51,557,900 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,551,596 - 51,557,940 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,759,378 - 50,765,691 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,186,311 - 51,192,625 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,427,359 - 51,433,667 (-)NCBIUU_Cfam_GSD_1.0
Rdh8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,909,060 - 209,915,152 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936659439,541 - 445,645 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RDH8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl268,871,707 - 68,877,675 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1268,871,707 - 68,878,222 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,199,776 - 69,206,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rdh8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,253,995 - 2,260,315 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,254,570 - 2,259,512 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 11 3
Below cutoff 4 6 25

Sequence


Reference Sequences
RefSeq Acc Id: XM_037992267   ⟹   XP_037848195
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607410,969,558 - 10,974,970 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037848195 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003711.1
Reference Protein Sequences
RefSeq Acc Id: XP_037848195   ⟸   XM_037992267


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007448 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005491.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene RDH8 ENTREZGENE
PANTHER RETINOL DEHYDROGENASE 8 UniProtKB/TrEMBL
  RETINOL DEHYDROGENASE-RELATED UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0D9R522_CHLSB UniProtKB/TrEMBL