 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 4. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Rreb1 (Rattus norvegicus - Norway rat) |
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| RREB1 (Homo sapiens - human) |
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| Rreb1 (Mus musculus - house mouse) |
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| Rreb1 (Chinchilla lanigera - long-tailed chinchilla) |
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| RREB1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| RREB1 (Canis lupus familiaris - dog) |
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| Rreb1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| RREB1 (Sus scrofa - pig) |
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Position Markers| RH133262 |
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| AA859655 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 15 | 27 | 4 | 15 | 4 | 3 | 11 | 11 | 33 | 35 | 8 | 8 | ||||
| Low | 7 | 16 | 19 | 3 | 8 | 26 | 25 | 8 | ||||||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001107348 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006253812 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006253813 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006253814 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006253815 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006253816 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006253817 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008771571 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07027386 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07027387 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01090803 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01090804 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01090805 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC090027 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473977 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ222841 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001107348 ⟹ NP_001100818 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
CTCGTTCTGCCGCGGCTGCTGCGGCAGCTCTGTAACACGTCCCTAGGAGACTCGCAGGAGCAAChide sequence |
| RefSeq Acc Id: | XM_006253812 ⟹ XP_006253874 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
AGCGGGGCGGGGGGCCGAGGCGGGGGCCGGGAAGACGGCTAGGGCAACGGGGTCGCCAGCTCCThide sequence |
| RefSeq Acc Id: | XM_006253813 ⟹ XP_006253875 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GGAAACTTTTCTCCTACATACTTTCTAGTCCCTCTCGGGTCGGGAAGCACGGAGATGACCGAGChide sequence |
| RefSeq Acc Id: | XM_006253814 ⟹ XP_006253876 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GCCTTCTTCGCCCTGGTCTGTCTCTAGAAGAGGTGGGCGTGGAGGACGGAGGAGTTGGGGTCCAhide sequence |
| RefSeq Acc Id: | XM_006253815 ⟹ XP_006253877 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GTGTGTGTGTGTGTGTGTGTGTAGGTAACTATTCAAAAGATGTATCCAAAACTGAGAACAAGTChide sequence |
| RefSeq Acc Id: | XM_006253816 ⟹ XP_006253878 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
AGCGGGGCGGGGGGCCGAGGCGGGGGCCGGGAAGACGGCTAGGGCAACGGGGTCGCCAGCTCCThide sequence |
| RefSeq Acc Id: | XM_006253817 ⟹ XP_006253879 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GTCTGTGGCTTGGGTGGTAGCAGCTAGTGGATTTTGTCTTGGAAGAATGTAGAGTAGACGTTCChide sequence |
| RefSeq Acc Id: | XM_008771571 ⟹ XP_008769793 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GGAAACTTTTCTCCTACATACTTTCTAGTCCCTCTCGGGTCGGGAAGCACGGAGATGACCGAGChide sequence |
Protein Sequences| Protein RefSeqs | NP_001100818 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006253874 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006253875 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006253876 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006253877 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006253878 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006253879 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008769793 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | EDL98267 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001100818 ⟸ NM_001107348 |
| - UniProtKB: | D3ZI11 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
| RefSeq Acc Id: | XP_006253876 ⟸ XM_006253814 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K4K0 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
| RefSeq Acc Id: | XP_006253877 ⟸ XM_006253815 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K4K0 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
| RefSeq Acc Id: | XP_006253878 ⟸ XM_006253816 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | D3ZI11 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
| RefSeq Acc Id: | XP_006253874 ⟸ XM_006253812 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K4K0 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
| RefSeq Acc Id: | XP_006253875 ⟸ XM_006253813 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K4K0 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
| RefSeq Acc Id: | XP_006253879 ⟸ XM_006253817 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIhide sequence |
| RefSeq Acc Id: | XP_008769793 ⟸ XM_008771571 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | D3ZI11 (UniProtKB/TrEMBL) |
| - Sequence: |
MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKShide sequence |
TranscriptomePromoters| RGD ID: | 13700398 | |||||||||
| Promoter ID: | EPDNEW_R10921 | |||||||||
| Type: | initiation region | |||||||||
| Name: | Rreb1_1 | |||||||||
| Description: | ras responsive element binding protein 1 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 17 | 29470907 | 29470908 | G | T | snv | BBDP/WorN (KNAW) |
| 17 | 29471351 | 29471352 | C | T | snv | MR/N (KNAW), MNS/Gib (KNAW), ZF (KyushuU), LEW/NCrl (KNAW), LEW/Crl (KNAW), WKY/NHsd (KNAW), HTX/Kyo (KyushuU), BUF/MNa (KyushuU), GK/Ox (KNAW), WKY/NCrl (KNAW), ZFDM (KyushuU), BBDP/WorN (KNAW), WKY/N (KNAW) |
| 17 | 29472796 | 29472797 | A | G | snv | FHH/EurMcwi (MCW), SR/JrHsd (MCW), ACI/EurMcwi (MCW) |
Assembly: Rnor_6.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 17 | 27556702 | 27556703 | G | T | snv | BBDP/Wor (RGD) |
| 17 | 27557146 | 27557147 | C | T | snv | WKY/NCrl (RGD), MNS/Gib (RGD), MR/N (MCW), LEW/Crl (RGD), CDS, LEW/NCrlBR (RGD), GK/Ox (RGD), WKY/N (MCW), BBDP/Wor (RGD), WKY/NHsd (RGD), CDR |
| 17 | 27558591 | 27558592 | A | G | snv | SR/JrHsd (MCW) |
Assembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 17 | 33143281 | 33143282 | C | T | snv | LEW/NCrl (ICL), WKY/NHsd (ICL), BBDP/WorN (ICL), HCR/1Mco (UMich), GK/Ox (ICL), LCR/1Mco (UMich), MNS/Gib (ICL), MR/N (KNAW), LEW/Crl (ICL), WKY/N (KNAW), WKY/NCrl (ICL) |
| 17 | 33144726 | 33144727 | A | G | snv | SR/JrHsd (MCW), FHH/EurMcwi (MCW), ACI/EurMcwi (MCW) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1310904 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000015701 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000056967 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000073072 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000060218 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000079298 | ENTREZGENE, UniProtKB/TrEMBL | |
| InterPro | Znf_C2H2/integrase_DNA-bd | UniProtKB/TrEMBL |
| Znf_C2H2_sf | UniProtKB/TrEMBL | |
| KEGG Report | rno:306873 | UniProtKB/TrEMBL |
| NCBI Gene | 306873 | ENTREZGENE |
| Pfam | zf-C2H2 | UniProtKB/TrEMBL |
| PhenoGen | Rreb1 | PhenoGen |
| PROSITE | ZINC_FINGER_C2H2_1 | UniProtKB/TrEMBL |
| ZINC_FINGER_C2H2_2 | UniProtKB/TrEMBL | |
| SMART | ZnF_C2H2 | UniProtKB/TrEMBL |
| Superfamily-SCOP | SSF57667 | UniProtKB/TrEMBL |
| UniGene | Rn.37 | ENTREZGENE |
| UniProt | A0A0G2K4K0 | ENTREZGENE, UniProtKB/TrEMBL |
| D3ZI11 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2008-04-30 | Rreb1 | ras responsive element binding protein 1 | Rreb1_predicted | ras responsive element binding protein 1 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Rreb1_predicted | ras responsive element binding protein 1 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Rreb1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1310904 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-08-20 |
| Status: | ACTIVE |
