Fahd1 (fumarylacetoacetate hydrolase domain containing 1) - Rat Genome Database

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Gene: Fahd1 (fumarylacetoacetate hydrolase domain containing 1) Rattus norvegicus
Analyze
Symbol: Fahd1
Name: fumarylacetoacetate hydrolase domain containing 1
RGD ID: 1304560
Description: Predicted to enable hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; oxaloacetate decarboxylase activity; and oxaloacetate tautomerase activity. Predicted to be involved in oxaloacetate metabolic process and pyruvate metabolic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in mitochondrion. Orthologous to human FAHD1 (fumarylacetoacetate hydrolase domain containing 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acylpyruvase FAHD1, mitochondrial; fumarylacetoacetate hydrolase domain-containing protein 1; LOC302980; OAA decarboxylase; oxaloacetate decarboxylase; oxaloacetate decarboxylase, mitochondrial; oxaloacetate tautomerase FAHD1, mitochondrial; RGD1304560; similar to RIKEN cDNA 1110025H10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Alc5 Alc9
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,378,058 - 14,379,497 (-)NCBIGRCr8
mRatBN7.21013,873,539 - 13,874,978 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,873,527 - 13,875,012 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,620,597 - 18,622,036 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,109,457 - 18,110,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,608,674 - 13,610,113 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,214,518 - 14,215,957 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,214,519 - 14,215,957 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,030,533 - 14,031,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,101,624 - 14,103,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11014,101,624 - 14,103,063 (-)NCBI
Celera1013,552,748 - 13,554,187 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fahd1Ratazoospermia  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: AzoospermiaClinVar 
Fahd1Ratdevelopmental and epileptic encephalopathy 1  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 1ClinVarPMID:28492532 and PMID:30866059
Fahd1Ratepilepsy  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: EpilepsyClinVarPMID:28492532
Fahd1RatIdiopathic Generalized Epilepsy  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: Idiopathic generalized epilepsyClinVarPMID:28492532
Fahd1RatPremature Ovarian Failure 23  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: Premature ovarian failure 23ClinVarPMID:31000419 and PMID:35991565
Fahd1Ratshort-rib thoracic dysplasia 9 with or without polydactyly  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: Saldino-Mainzer syndromeClinVarPMID:28492532
Fahd1Ratspermatogenic failure 22  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spermatogenic failure 22ClinVarPMID:35991565
Fahd1Rattuberous sclerosis 2  ISOFAHD1 (Homo sapiens)8554872ClinVar Annotator: match by term: Tuberous sclerosis 2ClinVarPMID:16114042 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fahd1RatExperimental Liver Cirrhosis  ISOFAHD1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136

1 to 20 of 79 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fahd1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of FAHD1 mRNA]CTDPMID:31150632
Fahd1Rat(1->4)-beta-D-glucan multiple interactionsISOFahd1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of FAHD1 mRNACTDPMID:36331819
Fahd1Rat1,2-dimethylhydrazine decreases expressionISOFahd1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of FAHD1 mRNACTDPMID:22206623
Fahd1Rat1,2-dimethylhydrazine multiple interactionsISOFahd1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FAHD1 mRNACTDPMID:22206623
Fahd1Rat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of FAHD1 mRNACTDPMID:25380136 and PMID:30723492
Fahd1Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of FAHD1 proteinCTDPMID:32145629
Fahd1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of FAHD1 mRNACTDPMID:21215274 and PMID:33387578
Fahd1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOFahd1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of FAHD1 mRNACTDPMID:21570461
Fahd1Rat3-chloropropane-1,2-diol decreases expressionEXP 6480464alpha-Chlorohydrin analog results in decreased expression of FAHD1 proteinCTDPMID:26597043
Fahd1Rat4,4'-diaminodiphenylmethane decreases expressionEXP 64804644 and 4'-diaminodiphenylmethane results in decreased expression of FAHD1 mRNACTDPMID:25380136
Fahd1Rat4,4'-sulfonyldiphenol increases expressionISOFahd1 (Mus musculus)6480464bisphenol S results in increased expression of FAHD1 mRNACTDPMID:39298647
Fahd1Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of FAHD1 mRNACTDPMID:31881176
Fahd1Rataflatoxin B1 decreases methylationISOFAHD1 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of FAHD1 geneCTDPMID:27153756
Fahd1Ratbenzo[a]pyrene increases expressionEXP 6480464Benzo(a)pyrene results in increased expression of FAHD1 mRNACTDPMID:21839799
Fahd1Ratbenzo[a]pyrene decreases expressionISOFAHD1 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of FAHD1 mRNACTDPMID:32234424
Fahd1Ratbenzo[a]pyrene increases methylationISOFAHD1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of FAHD1 3' UTRCTDPMID:27901495
Fahd1Ratbenzo[a]pyrene diol epoxide I decreases expressionISOFAHD1 (Homo sapiens)64804647 more ...CTDPMID:19150397
Fahd1Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of FAHD1 mRNA and bisphenol A results in increased expression of FAHD1 proteinCTDPMID:25181051 and PMID:32145629
Fahd1Ratbisphenol A decreases expressionISOFAHD1 (Homo sapiens)6480464bisphenol A results in decreased expression of FAHD1 mRNACTDPMID:33670352
Fahd1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of FAHD1 mRNACTDPMID:30816183 and PMID:32528016

1 to 20 of 79 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fahd1Ratoxaloacetate metabolic process involved_inISSUniProtKB:Q6P5871600115GO_REF:0000024UniProtGO_REF:0000024
Fahd1Ratoxaloacetate metabolic process involved_inIEAUniProtKB:Q6P587 and ensembl:ENSP000003980531600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratoxaloacetate metabolic process involved_inISOFAHD1 (Homo sapiens)1624291 PMID:38287013RGDPMID:38287013

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fahd1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Fahd1Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Fahd1Ratcytosol located_inISOFAHD1 (Homo sapiens)1624291 PMID:21878618RGDPMID:21878618
Fahd1Ratcytosol located_inISSUniProtKB:Q6P5871600115GO_REF:0000024UniProtGO_REF:0000024
Fahd1Ratcytosol located_inIEAUniProtKB:Q6P587 and ensembl:ENSP000003980531600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratmitochondrion located_inISOFAHD1 (Homo sapiens)1624291 PMID:21878618RGDGO_REF:0000052 more ...
Fahd1Ratmitochondrion located_inIEAUniProtKB:Q6P587 and ensembl:ENSP000003980531600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratmitochondrion located_inIEAUniProtKB-SubCell:SL-01731600115GO_REF:0000044UniProtGO_REF:0000044
Fahd1Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Fahd1Ratmitochondrion located_inISSUniProtKB:Q6P5871600115GO_REF:0000024UniProtGO_REF:0000024
Fahd1Ratmitochondrion is_active_inIBAPANTHER:PTN000214043 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fahd1Ratnucleoplasm located_inIEAUniProtKB:Q6P587 and ensembl:ENSP000003980531600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratnucleoplasm located_inISOFAHD1 (Homo sapiens)1624291 RGDGO_REF:0000052
1 to 13 of 13 rows

Molecular Function
1 to 20 of 28 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fahd1Ratacetylpyruvate hydrolase activity enablesISOFAHD1 (Homo sapiens)1624291 PMID:21878618RGDPMID:21878618
Fahd1Ratacetylpyruvate hydrolase activity enablesIEARHEA:160971600115GO_REF:0000116RHEAGO_REF:0000116
Fahd1Ratacetylpyruvate hydrolase activity enablesIEAUniProtKB:Q6P587 and ensembl:ENSP000003980531600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratacetylpyruvate hydrolase activity enablesIBAPANTHER:PTN000214041 and UniProtKB:Q6P5871600115GO_REF:0000033GO_CentralGO_REF:0000033
Fahd1Ratacetylpyruvate hydrolase activity enablesISSUniProtKB:Q6P5871600115GO_REF:0000024UniProtGO_REF:0000024
Fahd1Ratacylpyruvate hydrolase activity enablesIEAEC:3.7.1.51600115GO_REF:0000003UniProtGO_REF:0000003
Fahd1Ratacylpyruvate hydrolase activity enablesIEARHEA:190091600115GO_REF:0000116RHEAGO_REF:0000116
Fahd1Ratcatalytic activity enablesIEAInterPro:IPR011234 and InterPro:IPR0366631600115GO_REF:0000002InterProGO_REF:0000002
Fahd1Ratfumarylpyruvate hydrolase activity enablesISSUniProtKB:Q6P5871600115GO_REF:0000024UniProtGO_REF:0000024
Fahd1Ratfumarylpyruvate hydrolase activity enablesIEARHEA:261681600115GO_REF:0000116RHEAGO_REF:0000116
Fahd1Ratfumarylpyruvate hydrolase activity enablesIEAUniProtKB:Q6P587 and ensembl:ENSP000003980531600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratfumarylpyruvate hydrolase activity enablesISOFAHD1 (Homo sapiens)1624291 PMID:21878618RGDPMID:21878618
Fahd1Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Fahd1Ratisomerase activity enablesIEAUniProtKB-KW:KW-04131600115GO_REF:0000043UniProtGO_REF:0000043
Fahd1Ratlyase activity enablesIEAUniProtKB-KW:KW-04561600115GO_REF:0000043UniProtGO_REF:0000043
Fahd1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Fahd1Ratoxaloacetate decarboxylase activity enablesISOFAHD1 (Homo sapiens)1624291 PMID:25575590RGDPMID:25575590
Fahd1Ratoxaloacetate decarboxylase activity enablesIEAUniProtKB:Q8R0F8 and ensembl:ENSMUSP000000558271600115GO_REF:0000107EnsemblGO_REF:0000107
Fahd1Ratoxaloacetate decarboxylase activity enablesISOFahd1 (Mus musculus)1624291MGI:6358775 PMID:25575590RGDPMID:25575590
Fahd1Ratoxaloacetate decarboxylase activity enablesIEARHEA:156411600115GO_REF:0000116RHEAGO_REF:0000116
1 to 20 of 28 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:12865426   PMID:14651853   PMID:15489334   PMID:18614015   PMID:21878618   PMID:25575590  



Fahd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,378,058 - 14,379,497 (-)NCBIGRCr8
mRatBN7.21013,873,539 - 13,874,978 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,873,527 - 13,875,012 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,620,597 - 18,622,036 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,109,457 - 18,110,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,608,674 - 13,610,113 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,214,518 - 14,215,957 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,214,519 - 14,215,957 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,030,533 - 14,031,972 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,101,624 - 14,103,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11014,101,624 - 14,103,063 (-)NCBI
Celera1013,552,748 - 13,554,187 (-)NCBICelera
Cytogenetic Map10q12NCBI
FAHD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,827,206 - 1,840,207 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,826,967 - 1,840,207 (+)EnsemblGRCh38hg38GRCh38
GRCh37161,877,207 - 1,890,208 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,817,226 - 1,830,173 (+)NCBINCBI36Build 36hg18NCBI36
Build 34161,817,225 - 1,818,909NCBI
Celera162,089,471 - 2,102,473 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,800,249 - 1,813,209 (+)NCBIHuRef
CHM1_1161,877,193 - 1,890,193 (+)NCBICHM1_1
T2T-CHM13v2.0161,842,993 - 1,856,076 (+)NCBIT2T-CHM13v2.0
Fahd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,067,866 - 25,069,276 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,067,866 - 25,069,338 (-)EnsemblGRCm39 Ensembl
GRCm381724,848,896 - 24,850,302 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,848,892 - 24,850,364 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,985,841 - 24,987,247 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,565,856 - 24,577,737 (-)NCBIMGSCv36mm8
Celera1725,375,861 - 25,377,266 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Fahd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544215,450,066 - 15,451,797 (-)NCBIChiLan1.0ChiLan1.0
LOC100975679
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,093,654 - 2,099,243 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,874,794 - 5,887,000 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016449,359 - 451,070 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FAHD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,082,536 - 39,084,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,070,562 - 39,083,971 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,321,707 - 40,323,374 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,399,045 - 39,400,712 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1639,075,779 - 39,077,446 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,048,338 - 39,050,005 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,527,051 - 39,528,718 (-)NCBIUU_Cfam_GSD_1.0
Fahd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,528,167 - 104,529,733 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366942,179,730 - 2,181,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAHD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,141,132 - 40,141,806 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114121,538,308 - 121,539,037 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FAHD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,731,150 - 1,732,086 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,731,239 - 1,731,913 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,351,613 - 29,352,918 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fahd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624913432,780 - 434,359 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Fahd1
4 total Variants

Predicted Target Of
Summary Value
Count of predictions:17
Count of miRNA genes:17
Interacting mature miRNAs:17
Transcripts:ENSRNOT00000019767
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat

1 to 10 of 25 rows
RH133587  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,873,671 - 13,873,891 (+)MAPPERmRatBN7.2
Rnor_6.01014,214,651 - 14,214,870NCBIRnor6.0
Rnor_5.01014,030,666 - 14,030,885UniSTSRnor5.0
RGSC_v3.41014,101,757 - 14,101,976UniSTSRGSC3.4
Celera1013,552,881 - 13,553,100UniSTS
Cytogenetic Map10q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000019767   ⟹   ENSRNOP00000019767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,873,527 - 13,875,012 (-)Ensembl
Rnor_6.0 Ensembl1014,214,519 - 14,215,957 (-)Ensembl
RefSeq Acc Id: NM_001024991   ⟹   NP_001020162
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,378,058 - 14,379,497 (-)NCBI
mRatBN7.21013,873,539 - 13,874,978 (-)NCBI
Rnor_6.01014,214,518 - 14,215,957 (-)NCBI
Rnor_5.01014,030,533 - 14,031,972 (-)NCBI
RGSC_v3.41014,101,624 - 14,103,063 (-)RGD
Celera1013,552,748 - 13,554,187 (-)RGD
Sequence:
Protein RefSeqs NP_001020162 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78950 (Get FASTA)   NCBI Sequence Viewer  
  EDM03881 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019767
  ENSRNOP00000019767.4
GenBank Protein Q6AYQ8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020162   ⟸   NM_001024991
- UniProtKB: Q6AYQ8 (UniProtKB/Swiss-Prot),   A6HCX6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019767   ⟸   ENSRNOT00000019767
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYQ8-F1-model_v2 AlphaFold Q6AYQ8 1-221 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697029
Promoter ID:EPDNEW_R7554
Type:multiple initiation site
Name:Fahd1_1
Description:fumarylacetoacetate hydrolase domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01014,215,968 - 14,216,028EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-25821 BioCyc
Ensembl Genes ENSRNOG00000014727 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019767 ENTREZGENE
  ENSRNOT00000019767.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.850.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110058 IMAGE-MGC_LOAD
InterPro Fumarylacetoacetase-like_C UniProtKB/Swiss-Prot
  Fumarylacetoacetase_C_sf UniProtKB/Swiss-Prot
KEGG Report rno:302980 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93802 IMAGE-MGC_LOAD
NCBI Gene 302980 ENTREZGENE
PANTHER ACYLPYRUVASE UniProtKB/Swiss-Prot
  ACYLPYRUVASE FAHD1, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam FAA_hydrolase UniProtKB/Swiss-Prot
PhenoGen Fahd1 PhenoGen
RatGTEx ENSRNOG00000014727 RatGTEx
Superfamily-SCOP SSF56529 UniProtKB/Swiss-Prot
UniProt A6HCX6 ENTREZGENE, UniProtKB/TrEMBL
  FAHD1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Fahd1  fumarylacetoacetate hydrolase domain containing 1  RGD1304560  similar to RIKEN cDNA 1110025H10  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1304560  similar to RIKEN cDNA 1110025H10  RGD1304560_predicted  similar to RIKEN cDNA 1110025H10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1304560_predicted  similar to RIKEN cDNA 1110025H10 (predicted)  LOC302980_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC302980_predicted  similar to RIKEN cDNA 1110025H10 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL