Itgb5 (integrin subunit beta 5) - Rat Genome Database

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Gene: Itgb5 (integrin subunit beta 5) Ictidomys tridecemlineatus
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Symbol: Itgb5
Name: integrin subunit beta 5
RGD ID: 12615885
Description: ENCODES a protein that exhibits integrin binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell migration (ortholog); cell-matrix adhesion (ortholog); endodermal cell differentiation (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); thyroid gland disease (ortholog); FOUND IN cell leading edge (ortholog); cell surface (ortholog); focal adhesion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: integrin beta-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602126,509,750 - 126,622,528 (+)NCBI
SpeTri2.0NW_004936725417,824 - 530,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Itgb5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602126,509,750 - 126,622,528 (+)NCBI
SpeTri2.0NW_004936725417,824 - 530,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3124,761,948 - 124,901,418 (-)EnsemblGRCh38hg38GRCh38
GRCh383124,761,948 - 124,901,418 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373124,480,795 - 124,620,265 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,964,485 - 126,088,834 (-)NCBINCBI36hg18NCBI36
Build 343125,964,485 - 126,088,834NCBI
Celera3122,889,001 - 123,012,953 (-)NCBI
Cytogenetic Map3q21.2NCBI
HuRef3121,856,362 - 121,980,193 (-)NCBIHuRef
CHM1_13124,443,929 - 124,568,716 (-)NCBICHM1_1
Itgb5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,650,035 - 33,769,708 (+)NCBIGRCm39mm39
GRCm39 Ensembl1633,650,035 - 33,769,708 (+)Ensembl
GRCm381633,829,665 - 33,949,338 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,829,665 - 33,949,338 (+)EnsemblGRCm38mm10GRCm38
MGSCv371633,829,751 - 33,949,424 (+)NCBIGRCm37mm9NCBIm37
MGSCv361633,749,506 - 33,868,893 (+)NCBImm8
Celera1634,313,798 - 34,433,456 (+)NCBICelera
Cytogenetic Map16B3NCBI
Itgb5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21166,828,428 - 66,944,231 (-)NCBI
Rnor_6.0 Ensembl1170,056,500 - 70,172,372 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01170,056,500 - 70,172,164 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01173,146,146 - 73,261,215 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11168,699,866 - 68,710,334 (+)NCBI
Celera1166,279,067 - 66,394,763 (-)NCBICelera
Cytogenetic Map11q22NCBI
Itgb5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542723,850,261 - 23,939,950 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542723,851,475 - 23,952,211 (-)NCBIChiLan1.0ChiLan1.0
ITGB5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13128,762,200 - 128,873,887 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3128,762,200 - 128,877,172 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03121,863,676 - 122,013,438 (-)NCBIMhudiblu_PPA_v0panPan3
ITGB5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13327,797,204 - 27,912,558 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3327,797,667 - 27,912,584 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3327,820,964 - 27,935,930 (-)NCBI
ROS_Cfam_1.03328,033,980 - 28,149,103 (-)NCBI
UMICH_Zoey_3.13327,829,232 - 27,945,045 (-)NCBI
UNSW_CanFamBas_1.03327,873,552 - 27,988,833 (-)NCBI
UU_Cfam_GSD_1.03328,492,316 - 28,607,994 (-)NCBI
ITGB5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13135,467,798 - 135,587,483 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113135,468,111 - 135,587,483 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,042,442 - 145,111,929 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12255,944,810 - 56,070,605 (+)NCBI
ChlSab1.1 Ensembl2255,944,865 - 56,069,930 (+)Ensembl
Vero_WHO_p1.0NW_023666041110,252,879 - 110,375,605 (-)NCBI
Itgb5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624731804,272 - 914,204 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005338875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005338875   ⟹   XP_005338932
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602126,509,750 - 126,622,528 (+)NCBI
SpeTri2.0NW_004936725417,824 - 530,993 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005338932 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005338932   ⟸   XM_005338875
- UniProtKB: A0A287CYP1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
INB   Integrin_b_cyt   Integrin_B_tail   PSI   VWFA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007965 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007138 UniProtKB/TrEMBL
  ENSSTOP00000026388 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007976 UniProtKB/TrEMBL
  ENSSTOT00000034317 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro I-EGF_1 UniProtKB/TrEMBL
  Integin_beta_N UniProtKB/TrEMBL
  Integrin_beta-5 UniProtKB/TrEMBL
  Integrin_bsu UniProtKB/TrEMBL
  Integrin_bsu_cyt_dom UniProtKB/TrEMBL
  Integrin_bsu_tail UniProtKB/TrEMBL
  Integrin_bsu_tail_dom_sf UniProtKB/TrEMBL
  Integrin_bsu_VWA UniProtKB/TrEMBL
  Integrin_dom UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Itgb5 ENTREZGENE
PANTHER PTHR10082 UniProtKB/TrEMBL
  PTHR10082:SF26 UniProtKB/TrEMBL
Pfam I-EGF_1 UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/TrEMBL
  Integrin_beta UniProtKB/TrEMBL
  PSI_integrin UniProtKB/TrEMBL
PIRSF Integrin_B UniProtKB/TrEMBL
PRINTS INTEGRINB UniProtKB/TrEMBL
PROSITE INTEGRIN_BETA UniProtKB/TrEMBL
SMART INB UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
  SSF69179 UniProtKB/TrEMBL
  SSF69687 UniProtKB/TrEMBL
UniProt A0A287CYP1 ENTREZGENE, UniProtKB/TrEMBL
  I3MAS5_ICTTR UniProtKB/TrEMBL