Wtap (WT1 associated protein) - Rat Genome Database

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Gene: Wtap (WT1 associated protein) Ictidomys tridecemlineatus
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Symbol: Wtap
Name: WT1 associated protein
RGD ID: 12590723
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN mRNA modification (inferred); mRNA processing (inferred); regulation of alternative mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101963588; pre-mRNA-splicing regulator WTAP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,966,743 - 143,997,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,227,156 - 11,249,818 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,222,513 - 11,249,432 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Wtap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,966,743 - 143,997,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,227,156 - 11,249,818 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,222,513 - 11,249,432 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WTAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,726,693 - 159,756,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,725,585 - 159,756,319 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,148,149 - 160,177,351 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,068,142 - 160,097,341 (+)NCBINCBI36Build 36hg18NCBI36
Celera6160,794,229 - 160,823,430 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,617,339 - 157,646,781 (+)NCBIHuRef
CHM1_16160,410,378 - 160,439,680 (+)NCBICHM1_1
T2T-CHM13v2.06160,967,457 - 161,001,943 (+)NCBIT2T-CHM13v2.0
Wtap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,185,686 - 13,211,430 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,185,683 - 13,213,056 (-)EnsemblGRCm39 Ensembl
GRCm381712,966,799 - 12,992,543 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,966,796 - 12,994,169 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,159,665 - 13,185,405 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,815,617 - 12,835,478 (-)NCBIMGSCv36mm8
Celera1712,998,333 - 13,025,542 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.73NCBI
Wtap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,070,973 - 50,096,074 (+)NCBIGRCr8
mRatBN7.2147,665,965 - 47,691,067 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,665,965 - 47,691,065 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,214,813 - 48,239,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,202,806 - 54,227,929 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,290,329 - 48,315,430 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,942,500 - 47,967,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,942,500 - 47,967,631 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,781,701 - 51,806,726 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,891,437 - 41,917,254 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera143,351,111 - 43,376,211 (+)NCBICelera
Cytogenetic Map1q11NCBI
Wtap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543921,146,206 - 21,182,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543921,149,970 - 21,174,479 (-)NCBIChiLan1.0ChiLan1.0
WTAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25179,824,106 - 179,854,540 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,729,160 - 177,759,590 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,609,779 - 157,639,122 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,620,947 - 162,650,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,621,842 - 162,650,683 (+)Ensemblpanpan1.1panPan2
WTAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,976,523 - 49,004,536 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,976,499 - 49,003,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,818,344 - 49,846,503 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,160,699 - 49,189,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,160,693 - 49,189,019 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,043,176 - 49,071,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,914,192 - 48,942,472 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,529,308 - 49,557,423 (+)NCBIUU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0149,480,343 - 49,508,532 (+)NCBIUU_Cfam_GSD_1.0
WTAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,622,547 - 7,651,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,622,544 - 7,651,732 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,419,861 - 9,447,657 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WTAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,328,228 - 87,357,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604059,727,150 - 59,756,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wtap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248553,205,543 - 3,235,979 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248553,205,543 - 3,236,134 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000019564   ⟹   ENSSTOP00000022589
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648911,230,190 - 11,248,738 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000032004   ⟹   ENSSTOP00000031219
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648911,227,156 - 11,249,818 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000034361   ⟹   ENSSTOP00000025320
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648911,230,433 - 11,240,196 (+)Ensembl
RefSeq Acc Id: XM_005321416   ⟹   XP_005321473
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946143,970,518 - 143,997,439 (+)NCBI
SpeTri2.0NW_00493648911,222,513 - 11,249,432 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040283511   ⟹   XP_040139445
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946143,966,743 - 143,997,439 (+)NCBI
RefSeq Acc Id: XM_040283512   ⟹   XP_040139446
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946143,966,798 - 143,997,439 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005321473 (Get FASTA)   NCBI Sequence Viewer  
  XP_040139445 (Get FASTA)   NCBI Sequence Viewer  
  XP_040139446 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000022589.2
  ENSSTOP00000025320.1
  ENSSTOP00000031219.1
GenBank Protein KAG3290521 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005321473   ⟸   XM_005321416
- UniProtKB: A0A287DCF8 (UniProtKB/TrEMBL),   I3NDZ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040139445   ⟸   XM_040283511
- UniProtKB: A0A287DCF8 (UniProtKB/TrEMBL),   I3NDZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040139446   ⟸   XM_040283512
- UniProtKB: A0A287DCF8 (UniProtKB/TrEMBL),   I3NDZ2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000022589   ⟸   ENSSTOT00000019564
Ensembl Acc Id: ENSSTOP00000031219   ⟸   ENSSTOT00000032004
Ensembl Acc Id: ENSSTOP00000025320   ⟸   ENSSTOT00000034361


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026157 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000019564.2 UniProtKB/TrEMBL
  ENSSTOT00000032004.1 UniProtKB/TrEMBL
  ENSSTOT00000034361.1 UniProtKB/TrEMBL
InterPro WTAP UniProtKB/TrEMBL
NCBI Gene Wtap ENTREZGENE
PANTHER FEMALE-LETHAL(2)D HOMOLOG UniProtKB/TrEMBL
  PTHR15217 UniProtKB/TrEMBL
Pfam Wtap UniProtKB/TrEMBL
UniProt A0A287CVH0_ICTTR UniProtKB/TrEMBL
  A0A287DCF8 ENTREZGENE, UniProtKB/TrEMBL
  I3NDZ2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 Wtap  WT1 associated protein  LOC101963588  WT1 associated protein  Symbol and/or name change 5135510 APPROVED
2021-03-26 LOC101963588  WT1 associated protein  Wtap  WT1 associated protein  Symbol and/or name change 5135510 APPROVED
2017-03-08 Wtap  WT1 associated protein    Wilms tumor 1 associated protein  Symbol and/or name change 5135510 APPROVED