WTAP (WT1 associated protein) - Rat Genome Database

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Gene: WTAP (WT1 associated protein) Chlorocebus sabaeus
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Symbol: WTAP
Name: WT1 associated protein
RGD ID: 18709519
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN mRNA processing (inferred); regulation of alternative mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nuclear membrane (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103240819; pre-mRNA-splicing regulator WTAP; Wilms tumor 1 associated protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,328,228 - 87,357,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604059,727,150 - 59,756,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WTAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,328,228 - 87,357,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604059,727,150 - 59,756,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
WTAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,726,693 - 159,756,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,725,585 - 159,756,319 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,148,149 - 160,177,351 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,068,142 - 160,097,341 (+)NCBINCBI36Build 36hg18NCBI36
Celera6160,794,229 - 160,823,430 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,617,339 - 157,646,781 (+)NCBIHuRef
CHM1_16160,410,378 - 160,439,680 (+)NCBICHM1_1
T2T-CHM13v2.06160,967,457 - 161,001,943 (+)NCBIT2T-CHM13v2.0
Wtap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,185,686 - 13,211,430 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,185,683 - 13,213,056 (-)EnsemblGRCm39 Ensembl
GRCm381712,966,799 - 12,992,543 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,966,796 - 12,994,169 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,159,665 - 13,185,405 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,815,617 - 12,835,478 (-)NCBIMGSCv36mm8
Celera1712,998,333 - 13,025,542 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.73NCBI
Wtap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,070,973 - 50,096,074 (+)NCBIGRCr8
mRatBN7.2147,665,965 - 47,691,067 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,665,965 - 47,691,065 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,214,813 - 48,239,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,202,806 - 54,227,929 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,290,329 - 48,315,430 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,942,500 - 47,967,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,942,500 - 47,967,631 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,781,701 - 51,806,726 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,891,437 - 41,917,254 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera143,351,111 - 43,376,211 (+)NCBICelera
Cytogenetic Map1q11NCBI
Wtap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543921,146,206 - 21,182,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543921,149,970 - 21,174,479 (-)NCBIChiLan1.0ChiLan1.0
WTAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25179,824,106 - 179,854,540 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,729,160 - 177,759,590 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,609,779 - 157,639,122 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,620,947 - 162,650,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,621,842 - 162,650,683 (+)Ensemblpanpan1.1panPan2
WTAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,976,523 - 49,004,536 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,976,499 - 49,003,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,818,344 - 49,846,503 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,160,699 - 49,189,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,160,693 - 49,189,019 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,043,176 - 49,071,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,914,192 - 48,942,472 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,529,308 - 49,557,423 (+)NCBIUU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0149,480,343 - 49,508,532 (+)NCBIUU_Cfam_GSD_1.0
Wtap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,966,743 - 143,997,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,227,156 - 11,249,818 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,222,513 - 11,249,432 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WTAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,622,547 - 7,651,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,622,544 - 7,651,732 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,419,861 - 9,447,657 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Wtap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248553,205,543 - 3,235,979 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248553,205,543 - 3,236,134 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: XM_008007722   ⟹   XP_008005913
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,328,513 - 87,357,868 (+)NCBI
Vero_WHO_p1.0NW_02366604059,727,497 - 59,756,923 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008007723   ⟹   XP_008005914
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,328,228 - 87,357,868 (+)NCBI
Vero_WHO_p1.0NW_02366604059,727,150 - 59,756,923 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008007724   ⟹   XP_008005915
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,328,513 - 87,350,236 (+)NCBI
Vero_WHO_p1.0NW_02366604059,727,497 - 59,749,393 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008007726   ⟹   XP_008005917
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,328,228 - 87,350,236 (+)NCBI
Vero_WHO_p1.0NW_02366604059,727,150 - 59,749,393 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008007727   ⟹   XP_008005918
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11387,328,228 - 87,350,236 (+)NCBI
Vero_WHO_p1.0NW_02366604059,727,150 - 59,749,393 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008005913 (Get FASTA)   NCBI Sequence Viewer  
  XP_008005914 (Get FASTA)   NCBI Sequence Viewer  
  XP_008005915 (Get FASTA)   NCBI Sequence Viewer  
  XP_008005917 (Get FASTA)   NCBI Sequence Viewer  
  XP_008005918 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008773.1
RefSeq Acc Id: XP_008005914   ⟸   XM_008007723
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RJI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005918   ⟸   XM_008007727
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008005917   ⟸   XM_008007726
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008005913   ⟸   XM_008007722
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RJI4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005915   ⟸   XM_008007724
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012594 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010683.1 UniProtKB/TrEMBL
InterPro WTAP UniProtKB/TrEMBL
NCBI Gene WTAP ENTREZGENE
PANTHER PRE-MRNA-SPLICING REGULATOR WTAP UniProtKB/TrEMBL
  WILMS' TUMOR 1-ASSOCIATING PROTEIN UniProtKB/TrEMBL
Pfam Wtap UniProtKB/TrEMBL
UniProt A0A0D9RJI4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 WTAP  WT1 associated protein  LOC103240819  WT1 associated protein  Symbol and/or name change 5135510 APPROVED
2020-12-08 LOC103240819  WT1 associated protein  WTAP  WT1 associated protein  Symbol and/or name change 5135510 APPROVED