Wtap (WT1 associated protein) - Rat Genome Database

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Gene: Wtap (WT1 associated protein) Heterocephalus glaber
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Symbol: Wtap
Name: WT1 associated protein
RGD ID: 18904630
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN mRNA modification (inferred); mRNA processing (inferred); regulation of alternative mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Pre-mRNA-splicing regulator WTAP; Wilms tumor 1 associated protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248553,205,543 - 3,235,979 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248553,205,543 - 3,236,134 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Wtap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248553,205,543 - 3,235,979 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248553,205,543 - 3,236,134 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
WTAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,726,693 - 159,756,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,725,585 - 159,756,319 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,148,149 - 160,177,351 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,068,142 - 160,097,341 (+)NCBINCBI36Build 36hg18NCBI36
Celera6160,794,229 - 160,823,430 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,617,339 - 157,646,781 (+)NCBIHuRef
CHM1_16160,410,378 - 160,439,680 (+)NCBICHM1_1
T2T-CHM13v2.06160,967,457 - 161,001,943 (+)NCBIT2T-CHM13v2.0
Wtap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,185,686 - 13,211,430 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,185,683 - 13,213,056 (-)EnsemblGRCm39 Ensembl
GRCm381712,966,799 - 12,992,543 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,966,796 - 12,994,169 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,159,665 - 13,185,405 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,815,617 - 12,835,478 (-)NCBIMGSCv36mm8
Celera1712,998,333 - 13,025,542 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.73NCBI
Wtap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,070,973 - 50,096,074 (+)NCBIGRCr8
mRatBN7.2147,665,965 - 47,691,067 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,665,965 - 47,691,065 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,214,813 - 48,239,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,202,806 - 54,227,929 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,290,329 - 48,315,430 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,942,500 - 47,967,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,942,500 - 47,967,631 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,781,701 - 51,806,726 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,891,437 - 41,917,254 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera143,351,111 - 43,376,211 (+)NCBICelera
Cytogenetic Map1q11NCBI
Wtap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543921,146,206 - 21,182,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543921,149,970 - 21,174,479 (-)NCBIChiLan1.0ChiLan1.0
WTAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25179,824,106 - 179,854,540 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,729,160 - 177,759,590 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,609,779 - 157,639,122 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,620,947 - 162,650,683 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,621,842 - 162,650,683 (+)Ensemblpanpan1.1panPan2
WTAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,976,523 - 49,004,536 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,976,499 - 49,003,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,818,344 - 49,846,503 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,160,699 - 49,189,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,160,693 - 49,189,019 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,043,176 - 49,071,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,914,192 - 48,942,472 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,529,308 - 49,557,423 (+)NCBIUU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0149,480,343 - 49,508,532 (+)NCBIUU_Cfam_GSD_1.0
Wtap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,966,743 - 143,997,439 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,227,156 - 11,249,818 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,222,513 - 11,249,432 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WTAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,622,547 - 7,651,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,622,544 - 7,651,732 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,419,861 - 9,447,657 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WTAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,328,228 - 87,357,868 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604059,727,150 - 59,756,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000011101   ⟹   ENSHGLP00000010978
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248553,205,543 - 3,235,979 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000011102   ⟹   ENSHGLP00000010979
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248553,206,220 - 3,225,379 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000011103   ⟹   ENSHGLP00000010980
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248553,214,529 - 3,224,815 (-)Ensembl
RefSeq Acc Id: XM_004869022   ⟹   XP_004869079
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248553,205,543 - 3,235,645 (-)NCBI
RefSeq Acc Id: XM_004869023   ⟹   XP_004869080
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248553,205,543 - 3,235,962 (-)NCBI
RefSeq Acc Id: XM_004869024   ⟹   XP_004869081
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248553,210,007 - 3,235,645 (-)NCBI
RefSeq Acc Id: XM_021247779   ⟹   XP_021103438
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248553,205,543 - 3,236,134 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004869079 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869080 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869081 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103438 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB06880 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000010978
  ENSHGLP00000010979
  ENSHGLP00100034340
GenBank Protein JAO00572 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021103438   ⟸   XM_021247779
- Peptide Label: isoform X1
- UniProtKB: G5BC69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869080   ⟸   XM_004869023
- Peptide Label: isoform X1
- UniProtKB: G5BC69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869079   ⟸   XM_004869022
- Peptide Label: isoform X1
- UniProtKB: G5BC69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869081   ⟸   XM_004869024
- Peptide Label: isoform X2
- UniProtKB: A0AAX6QAY8 (UniProtKB/TrEMBL),   G5BQG5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010979   ⟸   ENSHGLT00000011102
Ensembl Acc Id: ENSHGLP00000010978   ⟸   ENSHGLT00000011101
Ensembl Acc Id: ENSHGLP00000010980   ⟸   ENSHGLT00000011103


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007879 Ensembl, ENTREZGENE
  ENSHGLG00100036567 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000011101 ENTREZGENE
  ENSHGLT00000011102 ENTREZGENE
  ENSHGLT00100042801 UniProtKB/TrEMBL
InterPro WTAP UniProtKB/TrEMBL
KEGG Report hgl:101713336 UniProtKB/TrEMBL
NCBI Gene Wtap ENTREZGENE
PANTHER FEMALE-LETHAL(2)D HOMOLOG UniProtKB/TrEMBL
  PTHR15217 UniProtKB/TrEMBL
Pfam Wtap UniProtKB/TrEMBL
UniProt A0AAX6QAY8 ENTREZGENE, UniProtKB/TrEMBL
  G5BC69 ENTREZGENE, UniProtKB/TrEMBL
  G5BQG5 ENTREZGENE, UniProtKB/TrEMBL