Elk1 (ETS transcription factor ELK1) - Rat Genome Database

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Gene: Elk1 (ETS transcription factor ELK1) Ictidomys tridecemlineatus
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Symbol: Elk1
Name: ETS transcription factor ELK1
RGD ID: 12589631
Description: ENCODES a protein that exhibits chromatin binding (ortholog); double-stranded DNA binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to gamma radiation (ortholog); cellular response to lipid (ortholog); cellular response to testosterone stimulus (ortholog); PARTICIPATES IN adenosine signaling pathway; hypoxia inducible factor pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); anxiety disorder (ortholog); autistic disorder (ortholog); FOUND IN axon terminus (ortholog); dendrite (ortholog); mitochondrial membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ELK1, ETS transcription factor; ELK1, ETS transcription factor, transcript variant X1; ELK1, ETS transcription factor, transcript variant X2; ELK1, ETS transcription factor, transcript variant X3; ETS domain-containing protein Elk-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,561,981 - 33,577,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650213,402,728 - 13,418,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650213,402,726 - 13,418,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Elk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,561,981 - 33,577,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650213,402,728 - 13,418,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650213,402,726 - 13,418,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,635,520 - 47,650,604 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,635,520 - 47,650,604 (-)EnsemblGRCh38hg38GRCh38
GRCh37X47,494,919 - 47,510,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X47,379,864 - 47,394,964 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X47,251,173 - 47,266,274NCBI
CeleraX51,690,183 - 51,705,266 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX45,207,767 - 45,222,756 (-)NCBIHuRef
CHM1_1X47,526,023 - 47,541,139 (-)NCBICHM1_1
T2T-CHM13v2.0X47,045,421 - 47,060,507 (-)NCBIT2T-CHM13v2.0
Elk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,799,634 - 20,816,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX20,799,634 - 20,816,847 (-)EnsemblGRCm39 Ensembl
GRCm38X20,933,395 - 20,950,608 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,933,395 - 20,950,608 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X20,510,521 - 20,527,726 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X20,091,886 - 20,107,552 (-)NCBIMGSCv36mm8
CeleraX19,067,257 - 19,084,739 (-)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX16.45NCBI
Elk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X3,692,367 - 3,709,252 (+)NCBIGRCr8
mRatBN7.2X1,138,826 - 1,155,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,139,756 - 1,155,713 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,167,915 - 1,183,790 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,643,607 - 4,659,482 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X964,852 - 980,733 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,287,875 - 1,304,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,297,099 - 1,304,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,102,893 - 2,119,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,597,863 - 12,604,248 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX1,708,719 - 1,724,604 (+)NCBICelera
Cytogenetic MapXq11NCBI
Elk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516430,775 - 444,871 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955516431,081 - 444,871 (+)NCBIChiLan1.0ChiLan1.0
ELK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X49,261,994 - 49,277,081 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X49,265,366 - 49,280,456 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,071,433 - 40,086,518 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X47,967,492 - 47,982,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,967,492 - 47,982,579 (-)Ensemblpanpan1.1panPan2
ELK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,256,205 - 41,270,656 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,257,482 - 41,270,776 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,630,809 - 15,645,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X41,390,004 - 41,404,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX41,390,011 - 41,404,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X41,377,550 - 41,392,091 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,365,833 - 41,380,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X41,458,515 - 41,473,055 (-)NCBIUU_Cfam_GSD_1.0
CFP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,157,988 - 42,174,951 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,157,980 - 42,174,964 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,303,918 - 47,320,907 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103231899
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X44,812,681 - 44,827,657 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666868398 - 6,908 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624978194,992 - 208,103 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624978194,985 - 208,105 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000009930   ⟹   ENSSTOP00000008908
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493650213,402,728 - 13,418,214 (-)Ensembl
RefSeq Acc Id: XM_005324028   ⟹   XP_005324085
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X33,561,981 - 33,577,464 (-)NCBI
SpeTri2.0NW_00493650213,402,734 - 13,418,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013358019   ⟹   XP_013213473
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X33,561,981 - 33,573,379 (-)NCBI
SpeTri2.0NW_00493650213,402,732 - 13,414,307 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021725593   ⟹   XP_021581268
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X33,561,981 - 33,573,637 (-)NCBI
SpeTri2.0NW_00493650213,402,726 - 13,414,419 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040279106   ⟹   XP_040135040
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X33,561,981 - 33,571,673 (-)NCBI
RefSeq Acc Id: XP_013213473   ⟸   XM_013358019
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005324085   ⟸   XM_005324028
- Peptide Label: isoform X2
- UniProtKB: I3MEI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021581268   ⟸   XM_021725593
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040135040   ⟸   XM_040279106
- Peptide Label: isoform X2
- UniProtKB: I3MEI5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000008908   ⟸   ENSSTOT00000009930
Protein Domains
ETS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009932 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009930.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Elk1 ENTREZGENE
PANTHER ETS DOMAIN-CONTAINING PROTEIN ELK-1 UniProtKB/TrEMBL
  PTHR11849 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt I3MEI5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Elk1  ETS transcription factor ELK1    ELK1, ETS transcription factor  Symbol and/or name change 5135510 APPROVED