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Gene: HAND2 (heart and neural crest derivatives expressed 2) Pan paniscus

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Symbol:

HAND2

Name:

heart and neural crest derivatives expressed 2

RGD ID:

11992677

Description:

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); E-box binding (ortholog); INVOLVED IN adult heart development (ortholog); apoptotic process (ortholog); apoptotic process involved in heart morphogenesis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); atrial fibrillation (ortholog); Cardiomegaly (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

heart- and neural crest derivatives-expressed protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	171,287,522 - 171,291,148 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	171,668,587 - 171,672,033 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	165,755,000 - 165,758,735 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	177,990,362 - 177,992,861 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAND2	Bonobo	Cardiomegaly		ISO	Hand2 (Rattus norvegicus)	9068941	mRNA:altered expression:cardiac ventricle	RGD	PMID:12359233 and REF_RGD_ID:727442
HAND2	Bonobo	Cardiomegaly		ISO	Hand2 (Mus musculus)	9068941	mRNA:decreased expression:heart right ventricle	RGD	PMID:12359233 and REF_RGD_ID:727442
HAND2	Bonobo	Right Ventricular Hypertrophy		ISO	Hand2 (Rattus norvegicus)	9068941	protein:increased expression:heart right ventricle	RGD	PMID:12955401 and REF_RGD_ID:5132894

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAND2	Bonobo	dilated cardiomyopathy 1A		ISO	HAND2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dilated cardiomyopathy 1A	ClinVar	PMID:26676105
HAND2	Bonobo	genetic disease		ISO	HAND2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868 and PMID:28492532
HAND2	Bonobo	Neurodevelopmental Disorders		ISO	HAND2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAND2	Bonobo	Animal Disease Models		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:29394407
HAND2	Bonobo	atrial fibrillation		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:28416822 more ...
HAND2	Bonobo	Cardiomegaly		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:29394407
HAND2	Bonobo	congenital heart disease		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:9671575
HAND2	Bonobo	congestive heart failure		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:29394407
HAND2	Bonobo	neuroblastoma		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:30127528
HAND2	Bonobo	tetralogy of Fallot		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25093829
HAND2	Bonobo	Ventricular Remodeling		ISO	HAND2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:29394407

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAND2	Bonobo	adult heart development	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:9878849	BHF-UCL	PMID:9878849
HAND2	Bonobo	adult heart development	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:9171826	MGI	PMID:9171826
HAND2	Bonobo	apoptotic process	acts_upstream_of	ISO	MGI:3715149	9068941	PMID:19341725	MGI	PMID:19341725
HAND2	Bonobo	apoptotic process involved in heart morphogenesis	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:11784028	MGI	PMID:11784028
HAND2	Bonobo	cardiac neural crest cell development involved in outflow tract morphogenesis	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	cardiac neural crest cell migration involved in outflow tract morphogenesis	acts_upstream_of_or_within	ISO	MGI:2386570 and MGI:3803647	9068941	PMID:20144608	MGI	PMID:20144608
HAND2	Bonobo	cardiac right ventricle formation	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:11076755	BHF-UCL	PMID:11076755
HAND2	Bonobo	cartilage morphogenesis	acts_upstream_of_or_within	ISO	MGI:103577	9068941	PMID:17764670	MGI	PMID:17764670
HAND2	Bonobo	cell proliferation involved in outflow tract morphogenesis	acts_upstream_of_or_within	ISO	MGI:2386570 and MGI:3803647	9068941	PMID:20144608	MGI	PMID:20144608
HAND2	Bonobo	cellular response to retinoic acid		ISO	Hand2 (Rattus norvegicus)	9068941		RGD	PMID:16619265 and REF_RGD_ID:5131544
HAND2	Bonobo	coronary artery morphogenesis	acts_upstream_of_or_within	ISO	MGI:3715149 and MGI:4838016	9068941	PMID:21350214	MGI	PMID:21350214
HAND2	Bonobo	determination of heart left/right asymmetry	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:9576835	MGI	PMID:9576835
HAND2	Bonobo	embryonic digit morphogenesis	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:12070084	MGI	PMID:12070084
HAND2	Bonobo	embryonic skeletal system development	involved_in	ISO	MGI:105923	9068941	PMID:19017795	MGI	PMID:19017795
HAND2	Bonobo	epithelial cell apoptotic process	acts_upstream_of	ISO	MGI:3715149	9068941	PMID:19341725	MGI	PMID:19341725
HAND2	Bonobo	heart development	involved_in	ISO	Hand2 (Rattus norvegicus)	9068941	PMID:15486975	UniProt	PMID:15486975 and REF_RGD_ID:8554739
HAND2	Bonobo	heart development	acts_upstream_of_or_within	ISO	MGI:103577	9068941	PMID:15576406	MGI	PMID:15576406
HAND2	Bonobo	heart looping	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:9171826	MGI	PMID:9171826
HAND2	Bonobo	heart morphogenesis	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:11784028	MGI	PMID:11784028
HAND2	Bonobo	in utero embryonic development	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:9171826	MGI	PMID:9171826
HAND2	Bonobo	mesenchymal cell proliferation	acts_upstream_of_or_within	ISO	MGI:3715149	9068941	PMID:19341725	MGI	PMID:19341725
HAND2	Bonobo	mesenchyme development	acts_upstream_of_or_within	ISO	MGI:103577	9068941	PMID:17764670	MGI	PMID:17764670
HAND2	Bonobo	negative regulation of cardiac muscle cell apoptotic process	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	negative regulation of DNA-binding transcription factor activity	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:19144722	MGI	PMID:19144722
HAND2	Bonobo	negative regulation of epithelial cell apoptotic process	acts_upstream_of_or_within	ISO	MGI:3715149	9068941	PMID:19341725	MGI	PMID:19341725
HAND2	Bonobo	negative regulation of gene expression	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	negative regulation of osteoblast differentiation	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:19144722	MGI	PMID:19144722
HAND2	Bonobo	negative regulation of osteoblast differentiation	acts_upstream_of_or_within	ISO	MGI:2653307	9068941	PMID:19144722	MGI	PMID:19144722
HAND2	Bonobo	neural crest cell development	acts_upstream_of_or_within	ISO	MGI:1857639	9068941	PMID:9671575	MGI	PMID:9671575
HAND2	Bonobo	norepinephrine biosynthetic process	acts_upstream_of_positive_effect	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	odontogenesis of dentin-containing tooth	acts_upstream_of_or_within	ISO	MGI:103577	9068941	PMID:17764670	MGI	PMID:17764670
HAND2	Bonobo	osteoblast differentiation	acts_upstream_of	ISO	MGI:2653307	9068941	PMID:19144722	MGI	PMID:19144722
HAND2	Bonobo	outflow tract morphogenesis	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	peripheral nervous system neuron development	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:16145670	MGI	PMID:16145670
HAND2	Bonobo	positive regulation of cardiac muscle hypertrophy	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	positive regulation of cardiac muscle hypertrophy	involved_in	ISO	UniProtKB:P63328 and UniProtKB:Q02078	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	positive regulation of DNA-templated transcription	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:16145670	MGI	PMID:16145670
HAND2	Bonobo	positive regulation of DNA-templated transcription	acts_upstream_of_or_within	ISO	MGI:98510	9068941	PMID:12070084	MGI	PMID:12070084
HAND2	Bonobo	positive regulation of ERK1 and ERK2 cascade	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	positive regulation of gene expression	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	positive regulation of p38MAPK cascade	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	positive regulation of semaphorin-plexin signaling pathway	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	positive regulation of transcription by RNA polymerase II	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	positive regulation of transcription by RNA polymerase II	acts_upstream_of_or_within	ISO	MGI:98510	9068941	PMID:20144608	MGI	PMID:20144608
HAND2	Bonobo	positive regulation of transcription by RNA polymerase II	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:15486975 more ...	UniProt	PMID:15486975 more ...
HAND2	Bonobo	positive regulation of transcription by RNA polymerase II	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:11812799	BHF-UCL	PMID:11812799
HAND2	Bonobo	primary palate development	acts_upstream_of_or_within	ISO	MGI:3715149	9068941	PMID:17531968	MGI	PMID:17531968
HAND2	Bonobo	regulation of DNA-templated transcription	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:15351717	MGI	PMID:15351717
HAND2	Bonobo	regulation of secondary heart field cardioblast proliferation	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	regulation of tissue remodeling	involved_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:24161931	BHF-UCL	PMID:24161931
HAND2	Bonobo	roof of mouth development	acts_upstream_of_or_within	ISO	MGI:3715149	9068941	PMID:17531968 and PMID:19341725	MGI	PMID:17531968 and PMID:19341725
HAND2	Bonobo	suckling behavior	acts_upstream_of_or_within	ISO	MGI:3715149	9068941	PMID:17531968	MGI	PMID:17531968
HAND2	Bonobo	sympathetic nervous system development	acts_upstream_of_or_within	ISO	Hand2 (Mus musculus)	9068941	PMID:16145670	MGI	PMID:16145670
HAND2	Bonobo	thymus development	involved_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19008477	BHF-UCL	PMID:19008477
HAND2	Bonobo	tongue development	acts_upstream_of_or_within	ISO	MGI:3715149	9068941	PMID:17531968	MGI	PMID:17531968
HAND2	Bonobo	visceral serous pericardium development	acts_upstream_of_or_within	ISO	MGI:3715149 and MGI:3801682	9068941	PMID:21350214	MGI	PMID:21350214

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAND2	Bonobo	chromatin	located_in	ISO	HAND2 (Homo sapiens)	9068941	PMID:16280598 and PMID:24161931	BHF-UCL	PMID:16280598 and PMID:24161931
HAND2	Bonobo	nucleus	located_in	ISO	Hand2 (Mus musculus)	9068941	PMID:19144722	MGI	PMID:19144722
HAND2	Bonobo	protein-containing complex	part_of	ISO	HAND2 (Homo sapiens)	9068941	PMID:15486975	UniProt	PMID:15486975
HAND2	Bonobo	transcription regulator complex	part_of	ISO	Hand2 (Mus musculus)	9068941	PMID:11812799	BHF-UCL	PMID:11812799

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAND2	Bonobo	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	ISO	Hand2 (Mus musculus)	9068941	PMID:11812799	BHF-UCL	PMID:11812799
HAND2	Bonobo	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	ISO	HAND2 (Homo sapiens)	9068941	PMID:15486975	UniProt	PMID:15486975
HAND2	Bonobo	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	ISO	Hand2 (Rattus norvegicus)	9068941	PMID:11994297	BHF-UCL	PMID:11994297 and REF_RGD_ID:727369
HAND2	Bonobo	E-box binding	contributes_to	ISO	Hand2 (Mus musculus)	9068941	PMID:11812799	BHF-UCL	PMID:11812799
HAND2	Bonobo	E-box binding	enables	ISO	Hand2 (Mus musculus)	9068941	PMID:20144608	MGI	PMID:20144608
HAND2	Bonobo	E-box binding	enables	ISO	HAND2 (Homo sapiens)	9068941	PMID:15486975	UniProt	PMID:15486975
HAND2	Bonobo	minor groove of adenine-thymine-rich DNA binding	enables	ISO	HAND2 (Homo sapiens)	9068941	PMID:15486975	UniProt	PMID:15486975
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:Q96CV9	9068941	PMID:32814053	IntAct	PMID:32814053
HAND2	Bonobo	protein binding	enables	ISO	PR:P42582	9068941	PMID:12392994	MGI	PMID:12392994
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:Q99N72	9068941	PMID:15102471	IntAct	PMID:15102471
HAND2	Bonobo	protein binding	enables	ISO	PR:P15806	9068941	PMID:12070084	MGI	PMID:12070084
HAND2	Bonobo	protein binding	enables	ISO	PR:P15806 more ...	9068941	PMID:15351717	MGI	PMID:15351717
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:Q06413	9068941	PMID:15486975	UniProt	PMID:15486975
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:Q64279	9068941	PMID:10924525	BHF-UCL	PMID:10924525
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:P15806 and UniProtKB:Q64279	9068941	PMID:10924525	IntAct	PMID:10924525
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:Q15327	9068941	PMID:20599664	BHF-UCL	PMID:20599664
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:P15884	9068941	PMID:25416956 and PMID:33961781	IntAct	PMID:25416956 and PMID:33961781
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:A0A096MJY4	9068941	PMID:15486975	UniProt	PMID:15486975 and REF_RGD_ID:8554739
HAND2	Bonobo	protein binding	enables	ISO	UniProtKB:Q0D2K3 more ...	9068941	PMID:32296183	IntAct	PMID:32296183
HAND2	Bonobo	protein homodimerization activity	enables	ISO	UniProtKB:Q61039	9068941	PMID:11812799	BHF-UCL	PMID:11812799
HAND2	Bonobo	RNA polymerase II transcription regulatory region sequence-specific DNA binding	enables	ISO	HAND2 (Homo sapiens)	9068941	PMID:16280598	BHF-UCL	PMID:16280598
HAND2	Bonobo	RNA polymerase II-specific DNA-binding transcription factor binding	enables	ISO	UniProtKB:P46152	9068941	PMID:11994297	BHF-UCL	PMID:11994297 and REF_RGD_ID:727369
HAND2	Bonobo	RNA polymerase II-specific DNA-binding transcription factor binding	enables	ISO	UniProtKB:P15806-1	9068941	PMID:11812799	BHF-UCL	PMID:11812799
HAND2	Bonobo	sequence-specific DNA binding	enables	ISO	MGI:98510	9068941	PMID:12070084	MGI	PMID:12070084
HAND2	Bonobo	sequence-specific double-stranded DNA binding	enables	ISO	HAND2 (Homo sapiens)	9068941	PMID:28473536	ARUK-UCL	PMID:28473536
HAND2	Bonobo	transcription cis-regulatory region binding	contributes_to	ISO	Hand2 (Mus musculus)	9068941	PMID:11812799	BHF-UCL	PMID:11812799
HAND2	Bonobo	transcription coactivator binding	enables	ISO	UniProtKB:Q8BJ14	9068941	PMID:11994297	BHF-UCL	PMID:11994297 and REF_RGD_ID:727369
HAND2	Bonobo	transcription factor binding		ISO	Mef2c (Rattus norvegicus)	9068941		RGD	PMID:15485823 and REF_RGD_ID:5132893

PMID:22301074	PMID:30032202

HAND2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	171,287,522 - 171,291,148 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	171,668,587 - 171,672,033 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	165,755,000 - 165,758,735 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	177,990,362 - 177,992,861 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

HAND2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	173,526,091 - 173,530,229 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	173,524,969 - 173,530,229 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	174,447,242 - 174,451,380 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	174,684,227 - 174,687,953 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	174,820,849 - 174,825,309	NCBI
Celera	4	171,772,735 - 171,776,461 (-)	NCBI		Celera
Cytogenetic Map	4	q34.1	NCBI
HuRef	4	170,194,314 - 170,197,710 (-)	NCBI		HuRef
CHM1_1	4	174,424,466 - 174,428,102 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	176,865,882 - 176,870,021 (-)	NCBI		T2T-CHM13v2.0

Hand2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	57,774,018 - 57,777,552 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	57,774,018 - 57,777,668 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	57,320,983 - 57,324,517 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	57,320,983 - 57,324,633 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	59,799,780 - 59,803,314 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	60,214,046 - 60,216,006 (+)	NCBI		MGSCv36	mm8
Celera	8	59,958,813 - 59,962,384 (+)	NCBI		Celera
Cytogenetic Map	8	B2	NCBI
cM Map	8	29.8	NCBI

Hand2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	37,928,145 - 37,931,488 (-)	NCBI		GRCr8
mRatBN7.2	16	32,917,448 - 32,920,791 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	32,917,823 - 32,919,891 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	36,510,401 - 36,513,743 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	39,921,734 - 39,925,076 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	36,141,350 - 36,144,691 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	36,371,489 - 36,373,551 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	36,371,489 - 36,373,546 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	36,173,054 - 36,174,762 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	36,324,327 - 36,348,104 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	36,324,401 - 36,326,112 (-)	NCBI
Celera	16	32,856,614 - 32,879,368 (-)	NCBI		Celera
Cytogenetic Map	16	p11	NCBI

Hand2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	33,478,924 - 33,481,608 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	33,478,034 - 33,481,613 (+)	NCBI	ChiLan1.0	ChiLan1.0

HAND2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	24,140,496 - 24,143,143 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	24,141,243 - 24,152,958 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	24,791,105 - 24,793,938 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	24,303,930 - 24,306,779 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	24,304,712 - 24,306,732 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	24,249,725 - 24,252,576 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	24,141,364 - 24,144,207 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	24,290,187 - 24,293,030 (-)	NCBI		UU_Cfam_GSD_1.0

Hand2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	24,277,871 - 24,281,346 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936516	4,692,926 - 4,695,632 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936516	4,692,926 - 4,695,625 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HAND2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	16,459,971 - 16,462,207 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	16,460,089 - 16,462,979 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	17,528,431 - 17,531,096 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HAND2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	119,635,697 - 119,639,415 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	119,634,741 - 119,638,546 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	99,666,888 - 99,670,603 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hand2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	5,033,932 - 5,038,343 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	5,035,669 - 5,038,333 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_003846131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_003846131 ⟹ XP_003846179

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	3	171,287,522 - 171,291,148 (-)	NCBI
NHGRI_mPanPan1	4	171,668,587 - 171,672,033 (-)	NCBI
Mhudiblu_PPA_v0	4	165,755,000 - 165,758,735 (-)	NCBI
PanPan1.1	4	177,990,362 - 177,992,861 (-)	NCBI

Sequence:

show sequence

CCGGTGAAGCGCCGAGGCACCGCCAACCGGAAGGAGCGGCGCAGGACTCAGAGCATCAACAGCGCCTTCGCCGAACTGCGCGAGTGCATCCCCAACGTACCCGCCGACACCAAACTCTCCAAAATCAA
GACCCTGCGCCTGGCCACCAGCTACATCGCCTACCTCATGGACCTGCTGGCCAAGGACGACCAGAATGGCGAGGCGGAGGCCTTCAAGGCAGAGATCAAGAAGACCGACGTGAAAGAGGAGAAGAGGA
AGAAGGAGCTGAACGAAATCTTGAAAAGCACAGTGAGCAGCAACGACAAGAAAACCAAAGGCCGGACGGGCTGGCCGCAGCACGTCTGGGCCCTGGAGCTCAAGCAGTGAGGAGGAGGAGGAGAAGGA
GGAGGAGGAGAGCGCGAGTGAGCAGGGGCCAAGGCGCCAGATGCAGACCCAGGACTCCGGAAAAGCCGTCCGCGCTCCGCTCTGAGGACTCCTTGCATTTGGAATCATCCGGTTTATTTATGTGCAAT
TTCCTTCCCCTCTCTTTGACCCCCTTTGAGGCATCCGCTCCCCGTCTCCCCCTCCAAAAAAAAGTGGATATTTGAAGAAAAGCATTCCATATTTTAATACGAAGAGGACACTCCCGTGTGGTAAGGGA
TCCCGTCGTCTCGTAGATTCTGTGTGCGTGAATGTTCCCTCTTGGCTGTGTAGACACCAGCGTTGCCCCCCGCCAACCTACTCAACCCCTTCCAGATAAAGACAGTGGGCACTAGTGCGTTTGTGAAG
TGTATCTTTAATACTTGGCCTTTGGATATAAATATTCCTGGGTATTATAAAGTTTTATTTCAAAGCAGAAAACAGGGCCGCTAACATTTCCGTTGGGGTCGGTATCTAGTGCTATCCGTTCATCTGTG
GTCGTTCCCTCTTTGAAGATGTTTCCAACAGCCACTTGTTTTGTGCACTTCCGTCCTCTAAAACTAAATGGAATTTAATTAATATTGAAGGTGTAAACGTTGTAAGTATTCAATAAACCACTGTGTTT
TTTTTACAAAAACCCTAATCTTTTAATGGTTGATACCTCAAGAGTTTTGAAAACAAAGCTGTTATACTTGTTTTCATAATATTTAAAATATTCAGAAGTAAACTAAATTATCATGA

hide sequence


Protein RefSeqs	XP_003846179	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_003846179 ⟸ XM_003846131
- Sequence:	show sequence PVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ hide sequence

Database	Acc Id	Source(s)
NCBI Gene	HAND2	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD