QKI (QKI, KH domain containing RNA binding) - Rat Genome Database

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Gene: QKI (QKI, KH domain containing RNA binding) Pan paniscus
Analyze
Symbol: QKI
Name: QKI, KH domain containing RNA binding
RGD ID: 11757653
Description: ENCODES a protein that exhibits internal N(7)-methylguanine-containing RNA reader activity (ortholog); miRNA binding (ortholog); mRNA 3'-UTR binding (ortholog); INVOLVED IN axon ensheathment (ortholog); intracellular mRNA localization (ortholog); long-chain fatty acid biosynthetic process (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH demyelinating disease (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); high grade glioma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: KH domain-containing RNA-binding protein QKI
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25183,597,079 - 183,756,086 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16181,498,349 - 181,657,357 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06161,361,413 - 161,523,414 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16166,398,884 - 166,517,389 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytoplasmic stress granule  (ISO)
cytosol  (ISO)
nucleus  (IEA,ISO)
synapse  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
QKI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25183,597,079 - 183,756,086 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16181,498,349 - 181,657,357 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06161,361,413 - 161,523,414 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16166,398,884 - 166,517,389 (+)NCBIpanpan1.1PanPan1.1panPan2
QKI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386163,414,718 - 163,578,592 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6163,414,000 - 163,578,592 (+)EnsemblGRCh38hg38GRCh38
GRCh376163,835,750 - 163,999,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366163,755,665 - 163,914,886 (+)NCBINCBI36Build 36hg18NCBI36
Celera6164,606,149 - 164,729,418 (+)NCBICelera
Cytogenetic Map6q26NCBI
HuRef6161,290,590 - 161,453,987 (+)NCBIHuRef
CHM1_16164,097,893 - 164,261,842 (+)NCBICHM1_1
T2T-CHM13v2.06164,779,884 - 164,943,697 (+)NCBIT2T-CHM13v2.0
Qki
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391710,425,480 - 10,538,706 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1710,421,530 - 10,538,783 (-)EnsemblGRCm39 Ensembl
GRCm381710,206,471 - 10,319,361 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1710,202,601 - 10,319,854 (-)EnsemblGRCm38mm10GRCm38
MGSCv371710,399,336 - 10,512,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361710,053,536 - 10,163,211 (-)NCBIMGSCv36mm8
Celera1710,252,038 - 10,337,960 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map177.75NCBI
Qki
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8152,935,357 - 53,047,338 (+)NCBIGRCr8
mRatBN7.2150,387,716 - 50,501,568 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl150,387,698 - 50,498,831 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0150,983,647 - 51,050,692 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl150,828,134 - 51,052,340 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0152,104,976 - 52,207,885 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4144,922,562 - 45,025,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera146,204,164 - 46,271,210 (+)NCBICelera
Cytogenetic Map1q11NCBI
Qki
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543917,925,229 - 18,079,727 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543917,925,205 - 18,079,727 (-)NCBIChiLan1.0ChiLan1.0
QKI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1151,800,294 - 51,956,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl151,800,309 - 51,952,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha152,642,145 - 52,797,414 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0151,975,526 - 52,138,964 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl151,977,027 - 52,136,022 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1151,867,832 - 52,023,107 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0151,727,887 - 51,883,146 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0152,356,356 - 52,511,535 (+)NCBIUU_Cfam_GSD_1.0
Qki
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946146,649,733 - 146,750,270 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648913,901,754 - 13,999,983 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648913,901,066 - 14,000,652 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
QKI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14,735,514 - 4,883,392 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114,732,575 - 4,883,386 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.216,380,698 - 6,486,326 (-)NCBISscrofa10.2Sscrofa10.2susScr3
QKI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11391,045,167 - 91,206,190 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1391,045,209 - 91,208,471 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604062,921,663 - 63,087,940 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Qki
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478515,739,187 - 15,845,024 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478515,738,231 - 15,845,051 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_034963214   ⟹   XP_034819105
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25183,597,079 - 183,756,086 (+)NCBI
NHGRI_mPanPan16181,498,349 - 181,657,357 (+)NCBI
Mhudiblu_PPA_v06161,361,413 - 161,523,414 (+)NCBI
RefSeq Acc Id: XM_034963216   ⟹   XP_034819107
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25183,597,079 - 183,756,086 (+)NCBI
NHGRI_mPanPan16181,498,349 - 181,657,357 (+)NCBI
Mhudiblu_PPA_v06161,361,488 - 161,523,414 (+)NCBI
RefSeq Acc Id: XM_034963217   ⟹   XP_034819108
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25183,597,079 - 183,756,086 (+)NCBI
NHGRI_mPanPan16181,498,349 - 181,657,357 (+)NCBI
Mhudiblu_PPA_v06161,361,413 - 161,520,523 (+)NCBI
RefSeq Acc Id: XM_034963218   ⟹   XP_034819109
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25183,597,079 - 183,756,086 (+)NCBI
NHGRI_mPanPan16181,498,349 - 181,657,357 (+)NCBI
Mhudiblu_PPA_v06161,361,413 - 161,520,523 (+)NCBI
RefSeq Acc Id: XM_034963219   ⟹   XP_034819110
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25183,597,087 - 183,752,417 (+)NCBI
NHGRI_mPanPan16181,498,690 - 181,653,694 (+)NCBI
Mhudiblu_PPA_v06161,361,827 - 161,516,858 (+)NCBI
RefSeq Acc Id: XP_034819105   ⟸   XM_034963214
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BKC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819108   ⟸   XM_034963217
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BKD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819109   ⟸   XM_034963218
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BL77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819107   ⟸   XM_034963216
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BKC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034819110   ⟸   XM_034963219
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BKD4 (UniProtKB/TrEMBL)
Protein Domains
K Homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038059 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053002.1 UniProtKB/TrEMBL
  ENSPPAT00000053007.1 UniProtKB/TrEMBL
  ENSPPAT00000053016.1 UniProtKB/TrEMBL
  ENSPPAT00000053017.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
InterPro BBP-like UniProtKB/TrEMBL
  KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  Quaking_NLS UniProtKB/TrEMBL
NCBI Gene QKI ENTREZGENE
PANTHER PROTEIN QUAKING UniProtKB/TrEMBL
  PROTEIN QUAKING UniProtKB/TrEMBL
  PTHR11208 UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
  Quaking_NLS UniProtKB/TrEMBL
SMART SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt A0A2R9BKB9_PANPA UniProtKB/TrEMBL
  A0A2R9BKC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BKD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BL77 ENTREZGENE, UniProtKB/TrEMBL