SLC6A1 (solute carrier family 6 member 1) - Rat Genome Database

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Gene: SLC6A1 (solute carrier family 6 member 1) Pan paniscus
Analyze
Symbol: SLC6A1
Name: solute carrier family 6 member 1
RGD ID: 11719554
Description: ENCODES a protein that exhibits amino acid:sodium symporter activity (ortholog); gamma-aminobutyric acid transmembrane transporter activity (ortholog); gamma-aminobutyric acid:sodium:chloride symporter activity (ortholog); INVOLVED IN associative learning (ortholog); gamma-aminobutyric acid import (ortholog); learning (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); amyotrophic lateral sclerosis (ortholog); Atrioventricular Septal Defect 2 (ortholog); FOUND IN cell surface (ortholog); GABA-ergic synapse (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2210,990,452 - 11,037,034 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1310,995,212 - 11,041,794 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0310,930,455 - 10,976,968 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1311,296,014 - 11,323,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl311,296,023 - 11,323,624 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC6A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2210,990,452 - 11,037,034 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1310,995,212 - 11,041,794 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0310,930,455 - 10,976,968 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1311,296,014 - 11,323,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl311,296,023 - 11,323,624 (+)Ensemblpanpan1.1panPan2
SLC6A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38310,992,748 - 11,039,247 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl310,992,186 - 11,039,247 (+)EnsemblGRCh38hg38GRCh38
GRCh37311,034,434 - 11,080,933 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36311,009,453 - 11,055,935 (+)NCBINCBI36Build 36hg18NCBI36
Build 34311,009,455 - 11,055,934NCBI
Celera310,969,866 - 11,016,381 (+)NCBICelera
Cytogenetic Map3p25.3ENTREZGENE
HuRef310,969,346 - 11,015,750 (+)NCBIHuRef
CHM1_1310,984,449 - 11,030,960 (+)NCBICHM1_1
T2T-CHM13v2.0310,987,230 - 11,033,712 (+)NCBIT2T-CHM13v2.0
Slc6a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396114,259,735 - 114,294,491 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6114,259,596 - 114,294,493 (+)EnsemblGRCm39 Ensembl
GRCm386114,282,635 - 114,317,525 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6114,282,635 - 114,317,532 (+)EnsemblGRCm38mm10GRCm38
MGSCv376114,232,629 - 114,267,519 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366114,248,369 - 114,283,117 (+)NCBIMGSCv36mm8
Celera6116,104,017 - 116,138,918 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.05NCBI
Slc6a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84149,004,447 - 149,037,840 (+)NCBIGRCr8
mRatBN7.24147,448,961 - 147,482,295 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4147,466,965 - 147,482,293 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4152,852,597 - 152,867,957 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04148,633,475 - 148,648,835 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04147,262,896 - 147,278,256 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04146,258,842 - 146,292,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4146,276,862 - 146,292,213 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04209,552,452 - 209,585,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44150,249,867 - 150,265,186 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14150,494,707 - 150,510,027 (+)NCBI
Celera4136,018,664 - 136,033,983 (+)NCBICelera
Cytogenetic Map4q42NCBI
Slc6a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542913,930,905 - 13,947,389 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542913,930,899 - 13,946,010 (+)NCBIChiLan1.0ChiLan1.0
SLC6A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1207,341,071 - 7,383,197 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl207,341,072 - 7,383,287 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha207,376,561 - 7,418,616 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0207,371,107 - 7,413,167 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl207,371,116 - 7,413,202 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1207,087,370 - 7,129,439 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0207,443,566 - 7,485,634 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0207,415,545 - 7,457,611 (-)NCBIUU_Cfam_GSD_1.0
Slc6a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494216,512,443 - 16,550,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366022,357,607 - 2,379,061 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366022,359,151 - 2,397,346 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1367,179,765 - 67,197,107 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11367,156,786 - 67,199,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21374,321,093 - 74,341,573 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC6A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12247,033,436 - 47,076,785 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2247,033,467 - 47,078,844 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041119,446,780 - 119,492,006 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624943631,632 - 662,902 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624943632,534 - 662,924 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000063284   ⟹   ENSPPAP00000040368
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl311,296,023 - 11,323,624 (+)Ensembl
RefSeq Acc Id: XM_008951725   ⟹   XP_008949973
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2211,010,367 - 11,037,034 (+)NCBI
NHGRI_mPanPan1311,015,127 - 11,041,794 (+)NCBI
Mhudiblu_PPA_v0310,950,306 - 10,974,997 (+)NCBI
PanPan1.1311,296,014 - 11,323,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034955788   ⟹   XP_034811679
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2210,990,467 - 11,037,034 (+)NCBI
NHGRI_mPanPan1310,995,227 - 11,041,794 (+)NCBI
Mhudiblu_PPA_v0310,930,455 - 10,976,968 (+)NCBI
RefSeq Acc Id: XM_034955789   ⟹   XP_034811680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2211,010,367 - 11,037,034 (+)NCBI
NHGRI_mPanPan1311,015,127 - 11,041,794 (+)NCBI
Mhudiblu_PPA_v0310,950,306 - 10,974,997 (+)NCBI
RefSeq Acc Id: XM_034955790   ⟹   XP_034811681
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2210,990,452 - 11,037,034 (+)NCBI
NHGRI_mPanPan1310,995,212 - 11,041,794 (+)NCBI
Mhudiblu_PPA_v0310,930,455 - 10,976,968 (+)NCBI
RefSeq Acc Id: XM_055109488   ⟹   XP_054965463
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2211,012,024 - 11,037,034 (+)NCBI
NHGRI_mPanPan1311,016,781 - 11,041,794 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008949973 (Get FASTA)   NCBI Sequence Viewer  
  XP_034811679 (Get FASTA)   NCBI Sequence Viewer  
  XP_034811680 (Get FASTA)   NCBI Sequence Viewer  
  XP_034811681 (Get FASTA)   NCBI Sequence Viewer  
  XP_054965463 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040368.1
RefSeq Acc Id: XP_008949973   ⟸   XM_008951725
- UniProtKB: A0A2R9CH47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034811679   ⟸   XM_034955788
- UniProtKB: A0A2R9CH47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811681   ⟸   XM_034955790
- UniProtKB: A0A2R9CH47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034811680   ⟸   XM_034955789
- UniProtKB: A0A2R9CH47 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000040368   ⟸   ENSPPAT00000063284
RefSeq Acc Id: XP_054965463   ⟸   XM_055109488
- UniProtKB: A0A2R9CH47 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063284.1 UniProtKB/TrEMBL
InterPro Na/ntran_symport UniProtKB/TrEMBL
  Na/ntran_symport_GABA_GAT1 UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
KEGG Report pps:100981601 UniProtKB/TrEMBL
NCBI Gene SLC6A1 ENTREZGENE
PANTHER PTHR11616 UniProtKB/TrEMBL
  SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1 UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS GAT1TRNSPORT UniProtKB/TrEMBL
  NANEUSMPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_2 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A2R9CH47 ENTREZGENE, UniProtKB/TrEMBL