Slc9a3 (solute carrier family 9 (sodium/hydrogen exchanger), member 3) - Rat Genome Database

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Gene: Slc9a3 (solute carrier family 9 (sodium/hydrogen exchanger), member 3) Mus musculus
Analyze
Symbol: Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
RGD ID: 11319
MGI Page MGI
Description: Enables PDZ domain binding activity and sodium:proton antiporter activity. Acts upstream of or within regulation of pH and sodium ion transport. Located in apical plasma membrane; brush border membrane; and vesicle. Is expressed in early conceptus; liver; metanephros; and oocyte. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8. Orthologous to human SLC9A3 (solute carrier family 9 member A3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9030624O13Rik; AI930210; NHE; NHE-; NHE-3; NHE3; sodium/hydrogen exchanger 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,234,374 - 74,317,561 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,269,576 - 74,317,561 (+)EnsemblGRCm39 Ensembl
GRCm381374,086,255 - 74,169,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,121,457 - 74,169,442 (+)EnsemblGRCm38mm10GRCm38
MGSCv371374,258,963 - 74,303,512 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,587,517 - 74,632,066 (+)NCBIMGSCv36mm8
Celera1376,451,103 - 76,495,653 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
acrylamide  (ISO)
aldosterone  (EXP)
all-trans-retinoic acid  (EXP)
ammonium chloride  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
chlorothalonil  (EXP)
choline  (EXP)
cimetidine  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
DDT  (EXP)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dimethylarsinic acid  (EXP)
enilconazole  (EXP)
folic acid  (EXP,ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
GW 4064  (EXP)
hydrogencarbonate  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
lithium atom  (ISO)
lithium hydride  (ISO)
losartan  (EXP)
mercury dichloride  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
naphthalene  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
piperine  (ISO)
procymidone  (EXP)
reactive nitrogen species  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SKF 38393  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sodium atom  (ISO)
sodium chloride  (ISO)
sotorasib  (ISO)
tamoxifen  (EXP)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
trametinib  (ISO)
tunicamycin  (EXP)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Altered expression of Na(+)/H(+) exchanger isoforms 1 and 3 in clipped and unclipped kidneys of a 2-kidney-1-clip Goldblatt model of hypertension. Khan I, etal., Nephron 2002 Oct;92(2):346-55.
2. Acute and Chronic Regulation of the Renal Na/H(+) Exchanger NHE3 in Rats with STZ-Induced Diabetes mellitus. Klisic J, etal., Nephron Physiol. 2005 Oct 19;102(2):p27-p35.
3. Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension. Leong PK, etal., Am J Physiol Renal Physiol 2002 Nov;283(5):F1142-50.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat. Riazi S, etal., Am J Nephrol. 2006;26(3):245-57. Epub 2006 Jun 2.
14. Molecular variants of the sodium/hydrogen exchanger type 3 gene and essential hypertension. Zhu H, etal., J Hypertens. 2004 Jul;22(7):1269-75.
Additional References at PubMed
PMID:8402911   PMID:8824815   PMID:9119405   PMID:9502765   PMID:9590530   PMID:9662405   PMID:10349636   PMID:10362780   PMID:10428871   PMID:10444585   PMID:10484528   PMID:10506152  
PMID:10666041   PMID:10666043   PMID:10772659   PMID:10822268   PMID:10841524   PMID:11042159   PMID:11076861   PMID:11099500   PMID:11139574   PMID:11158268   PMID:11208547   PMID:11217851  
PMID:11358967   PMID:11457720   PMID:11553519   PMID:11698654   PMID:11705743   PMID:11960774   PMID:12169661   PMID:12176733   PMID:12370192   PMID:12582007   PMID:12690468   PMID:12842825  
PMID:12911544   PMID:14500765   PMID:14633135   PMID:14962844   PMID:15113744   PMID:15284023   PMID:15550620   PMID:15604231   PMID:15780093   PMID:16141072   PMID:16141073   PMID:16141316  
PMID:16144961   PMID:16251474   PMID:16410368   PMID:16690903   PMID:16825708   PMID:17016558   PMID:17347851   PMID:17395628   PMID:17580307   PMID:18046080   PMID:18407958   PMID:18467500  
PMID:18758809   PMID:18930060   PMID:19088451   PMID:19164484   PMID:19420731   PMID:19521566   PMID:19713718   PMID:19800338   PMID:19855135   PMID:20026617   PMID:20164375   PMID:20962002  
PMID:21106755   PMID:21191106   PMID:21252044   PMID:21415416   PMID:21430287   PMID:21561868   PMID:21873635   PMID:21937605   PMID:21947296   PMID:22073226   PMID:22358497   PMID:22683701  
PMID:23054255   PMID:23086913   PMID:23508938   PMID:23548792   PMID:23677982   PMID:23764894   PMID:23784542   PMID:23863468   PMID:24018950   PMID:24029465   PMID:24072680   PMID:24233434  
PMID:24297041   PMID:24928903   PMID:25271043   PMID:25377912   PMID:25480791   PMID:25925253   PMID:26098432   PMID:26242933   PMID:26258413   PMID:26377793   PMID:26744474   PMID:26786190  
PMID:26807585   PMID:27019864   PMID:27050757   PMID:27279487   PMID:27371534   PMID:27390324   PMID:27626380   PMID:27822917   PMID:27995414   PMID:28384194   PMID:28385297   PMID:28566500  
PMID:28882822   PMID:29167115   PMID:29286340   PMID:30571224   PMID:30797621   PMID:30956978   PMID:31166707   PMID:31276916   PMID:31352824   PMID:31748650   PMID:32025032   PMID:32227118  
PMID:32557227   PMID:33904662   PMID:34822321   PMID:34823064   PMID:34978760   PMID:35635321   PMID:35719363   PMID:36042372   PMID:36555438   PMID:36916397   PMID:37350393   PMID:37471646  
PMID:37682076   PMID:38355793   PMID:38533975  


Genomics

Comparative Map Data
Slc9a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,234,374 - 74,317,561 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,269,576 - 74,317,561 (+)EnsemblGRCm39 Ensembl
GRCm381374,086,255 - 74,169,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,121,457 - 74,169,442 (+)EnsemblGRCm38mm10GRCm38
MGSCv371374,258,963 - 74,303,512 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,587,517 - 74,632,066 (+)NCBIMGSCv36mm8
Celera1376,451,103 - 76,495,653 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
SLC9A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385470,456 - 524,449 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5470,456 - 524,449 (-)EnsemblGRCh38hg38GRCh38
GRCh375470,571 - 524,564 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365526,425 - 577,447 (-)NCBINCBI36Build 36hg18NCBI36
Build 345526,424 - 577,447NCBI
Celera5570,966 - 620,781 (-)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef5460,638 - 510,183 (-)NCBIHuRef
CHM1_15472,597 - 524,559 (-)NCBICHM1_1
T2T-CHM13v2.05465,265 - 518,871 (-)NCBIT2T-CHM13v2.0
Slc9a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,953,215 - 30,996,209 (-)NCBIGRCr8
mRatBN7.2129,124,633 - 29,167,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,124,674 - 29,167,417 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,926,541 - 28,969,373 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,926,400 - 34,969,224 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,127,163 - 29,169,987 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,731,652 - 31,777,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,734,327 - 31,777,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,159,607 - 33,201,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,930,908 - 29,973,686 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,933,852 - 29,976,631 (-)NCBI
Celera127,776,582 - 27,819,219 (-)NCBICelera
Cytogenetic Map1p11NCBI
Slc9a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504228,049 - 260,650 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955504226,192 - 260,632 (-)NCBIChiLan1.0ChiLan1.0
LOC100988373
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,257,212 - 112,299,973 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,258,794 - 112,305,293 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05444,720 - 500,121 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15597,897 - 646,108 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5597,897 - 647,464 (-)Ensemblpanpan1.1panPan2
SLC9A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,748,556 - 11,785,209 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,748,175 - 11,785,786 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3416,258,013 - 16,298,999 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,649,118 - 11,689,897 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,649,113 - 11,690,798 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,699,849 - 11,740,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,680,359 - 11,721,422 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,890,462 - 11,930,512 (+)NCBIUU_Cfam_GSD_1.0
Slc9a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,802,254 - 244,839,418 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815963,715 - 999,280 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815963,715 - 999,280 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC9A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,666,825 - 79,700,658 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,625,555 - 79,704,084 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103214902
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.14362,417 - 408,113 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl4365,135 - 408,033 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606427,500,607 - 27,511,358 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc9a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751256,305 - 291,178 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751254,373 - 290,218 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc9a3
2829 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:130
Interacting mature miRNAs:136
Transcripts:ENSMUST00000036208
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse

Markers in Region
AI930210  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381374,169,322 - 74,169,404UniSTSGRCm38
MGSCv371374,306,770 - 74,306,852UniSTSGRCm37
Celera1376,498,911 - 76,498,993UniSTS
Cytogenetic Map13C1UniSTS
cM Map1343.0UniSTS
Whitehead/MRC_RH13667.43UniSTS
Slc9a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C1UniSTS
cM Map1343.0UniSTS
Slc9a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000036208   ⟹   ENSMUSP00000038142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1374,269,634 - 74,314,183 (+)Ensembl
GRCm38.p6 Ensembl1374,121,515 - 74,166,064 (+)Ensembl
Ensembl Acc Id: ENSMUST00000221410
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1374,269,576 - 74,279,010 (+)Ensembl
GRCm38.p6 Ensembl1374,121,457 - 74,130,891 (+)Ensembl
Ensembl Acc Id: ENSMUST00000221703   ⟹   ENSMUSP00000152682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1374,269,634 - 74,317,561 (+)Ensembl
GRCm38.p6 Ensembl1374,121,515 - 74,169,442 (+)Ensembl
Ensembl Acc Id: ENSMUST00000225423   ⟹   ENSMUSP00000153255
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1374,269,634 - 74,315,282 (+)Ensembl
GRCm38.p6 Ensembl1374,121,515 - 74,167,163 (+)Ensembl
RefSeq Acc Id: NM_001081060   ⟹   NP_001074529
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391374,269,532 - 74,317,561 (+)NCBI
GRCm381374,121,413 - 74,169,441 (+)NCBI
MGSCv371374,258,963 - 74,303,512 (+)RGD
Celera1376,451,103 - 76,495,653 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517021   ⟹   XP_006517084
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391374,234,374 - 74,317,561 (+)NCBI
GRCm381374,086,255 - 74,169,442 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517022   ⟹   XP_006517085
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391374,269,484 - 74,317,561 (+)NCBI
GRCm381374,121,367 - 74,169,442 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001074529   ⟸   NM_001081060
- Peptide Label: precursor
- UniProtKB: Q8BZU0 (UniProtKB/Swiss-Prot),   G3X939 (UniProtKB/Swiss-Prot),   A0A286YD40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517084   ⟸   XM_006517021
- Peptide Label: isoform X1
- UniProtKB: A0A286YD40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517085   ⟸   XM_006517022
- Peptide Label: isoform X2
- UniProtKB: Q8BZU0 (UniProtKB/Swiss-Prot),   G3X939 (UniProtKB/Swiss-Prot),   A0A286YD40 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000153255   ⟸   ENSMUST00000225423
Ensembl Acc Id: ENSMUSP00000038142   ⟸   ENSMUST00000036208
Ensembl Acc Id: ENSMUSP00000152682   ⟸   ENSMUST00000221703
Protein Domains
Cation/H+ exchanger

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3X939-F1-model_v2 AlphaFold G3X939 1-829 view protein structure

Promoters
RGD ID:8680826
Promoter ID:EPDNEW_M18444
Type:multiple initiation site
Name:Slc9a3_1
Description:Mus musculus solute carrier family 9 (sodium/hydrogen exchanger),member 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381374,121,415 - 74,121,475EPDNEW
RGD ID:6824405
Promoter ID:MM_KWN:14682
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NM_001081060
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361374,258,661 - 74,259,161 (+)MPROMDB
RGD ID:6824407
Promoter ID:MM_KWN:14684
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:UC007RET.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361374,300,811 - 74,302,112 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105064 AgrOrtholog
Ensembl Genes ENSMUSG00000036123 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000036208 ENTREZGENE
  ENSMUST00000036208.7 UniProtKB/Swiss-Prot
  ENSMUST00000221703 ENTREZGENE
  ENSMUST00000221703.2 UniProtKB/Swiss-Prot
  ENSMUST00000225423.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cation/H_exchanger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cation/H_exchanger_CPA1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/H_exchanger_3/5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NaH_exchanger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Reg_factor_effector_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:105243 UniProtKB/Swiss-Prot
MGD MGI:105064 ENTREZGENE
NCBI Gene Slc9a3 ENTREZGENE
PANTHER PTHR10110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SODIUM/HYDROGEN EXCHANGER 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Na_H_Exchanger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc9a3 PhenoGen
PRINTS NAHEXCHNGR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAHEXCHNGR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55136 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286YD40 ENTREZGENE, UniProtKB/TrEMBL
  G3X939 ENTREZGENE
  Q8BZU0 ENTREZGENE
  Q9WUJ5_MOUSE UniProtKB/TrEMBL
  SL9A3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8BZU0 UniProtKB/Swiss-Prot