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Gene: SLC9A5 (solute carrier family 9 member A5) Homo sapiens
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Symbol: SLC9A5
Name: solute carrier family 9 member A5
Description: Predicted to have potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to localize to the plasma membrane. Implicated in end stage renal failure; INTERACTS WITH 17beta-estradiol; 3-Iodothyronamine; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Na(+)/H(+) exchanger 5; NHE-5; NHE5; sodium/hydrogen exchanger 5; solute carrier family 9 (sodium/hydrogen exchanger), isoform 5; solute carrier family 9 (sodium/hydrogen exchanger), member 5; solute carrier family 9 member 5; solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
Orthologs:
Mus musculus (house mouse) : Slc9a5 (solute carrier family 9 (sodium/hydrogen exchanger), member 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc9a5 (solute carrier family 9 member A5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a5 (solute carrier family 9 member A5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A5 (solute carrier family 9 member A5)
Canis lupus familiaris (dog) : SLC9A5 (solute carrier family 9 member A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a5 (solute carrier family 9 member A5)
Sus scrofa (pig) : SLC9A5 (solute carrier family 9 member A5)
Chlorocebus sabaeus (African green monkey) : SLC9A5 (solute carrier family 9 member A5)
Heterocephalus glaber (naked mole-rat) : Slc9a5 (solute carrier family 9 member A5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1667,237,683 - 67,272,191 (+)Ensembl
GRCh381667,247,549 - 67,272,191 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371667,282,855 - 67,306,094 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,840,356 - 65,863,595 (+)NCBINCBI36hg18NCBI36
Build 341665,840,353 - 65,863,594NCBI
Celera1651,791,089 - 51,814,319 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1653,155,929 - 53,179,176 (+)NCBIHuRef
CHM1_11668,690,103 - 68,713,466 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC9A5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732088
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.