Slc9a3 (solute carrier family 9 member A3) - Rat Genome Database

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Gene: Slc9a3 (solute carrier family 9 member A3) Chinchilla lanigera
Analyze
Symbol: Slc9a3
Name: solute carrier family 9 member A3
RGD ID: 8915665
Description: ENCODES a protein that exhibits identical protein binding (ortholog); PDZ domain binding (ortholog); phosphatidylinositol binding (ortholog); INVOLVED IN circadian rhythm (ortholog); receptor-mediated endocytosis (ortholog); regulation of intracellular pH (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant dyskeratosis congenita 2 (ortholog); congenital secretory sodium diarrhea 8 (ortholog); FOUND IN apical plasma membrane (ortholog); brush border (ortholog); brush border membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/hydrogen exchanger 3; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504228,049 - 260,650 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955504226,192 - 260,632 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc9a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504228,049 - 260,650 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955504226,192 - 260,632 (-)NCBIChiLan1.0ChiLan1.0
SLC9A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385470,456 - 524,449 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5470,456 - 524,449 (-)EnsemblGRCh38hg38GRCh38
GRCh375470,571 - 524,564 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365526,425 - 577,447 (-)NCBINCBI36Build 36hg18NCBI36
Build 345526,424 - 577,447NCBI
Celera5570,966 - 620,781 (-)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef5460,638 - 510,183 (-)NCBIHuRef
CHM1_15472,597 - 524,559 (-)NCBICHM1_1
T2T-CHM13v2.05465,265 - 518,871 (-)NCBIT2T-CHM13v2.0
Slc9a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,234,374 - 74,317,561 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,269,576 - 74,317,561 (+)EnsemblGRCm39 Ensembl
GRCm381374,086,255 - 74,169,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,121,457 - 74,169,442 (+)EnsemblGRCm38mm10GRCm38
MGSCv371374,258,963 - 74,303,512 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,587,517 - 74,632,066 (+)NCBIMGSCv36mm8
Celera1376,451,103 - 76,495,653 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
Slc9a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,953,215 - 30,996,209 (-)NCBIGRCr8
mRatBN7.2129,124,633 - 29,167,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,124,674 - 29,167,417 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,926,541 - 28,969,373 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,926,400 - 34,969,224 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,127,163 - 29,169,987 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,731,652 - 31,777,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,734,327 - 31,777,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,159,607 - 33,201,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,930,908 - 29,973,686 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,933,852 - 29,976,631 (-)NCBI
Celera127,776,582 - 27,819,219 (-)NCBICelera
Cytogenetic Map1p11NCBI
LOC100988373
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,257,212 - 112,299,973 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,258,794 - 112,305,293 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05444,720 - 500,121 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15597,897 - 646,108 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5597,897 - 647,464 (-)Ensemblpanpan1.1panPan2
SLC9A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,748,556 - 11,785,209 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,748,175 - 11,785,786 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3416,258,013 - 16,298,999 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,649,118 - 11,689,897 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,649,113 - 11,690,798 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,699,849 - 11,740,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,680,359 - 11,721,422 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,890,462 - 11,930,512 (+)NCBIUU_Cfam_GSD_1.0
Slc9a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,802,254 - 244,839,418 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815963,715 - 999,280 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815963,715 - 999,280 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC9A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,666,825 - 79,700,658 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,625,555 - 79,704,084 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103214902
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.14362,417 - 408,113 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl4365,135 - 408,033 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606427,500,607 - 27,511,358 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc9a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751256,305 - 291,178 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751254,373 - 290,218 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000006172   ⟹   ENSCLAP00000006069
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955504228,049 - 260,650 (-)Ensembl
RefSeq Acc Id: XM_005407000   ⟹   XP_005407057
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955504226,192 - 260,632 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005407001   ⟹   XP_005407058
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955504226,192 - 260,632 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407057 (Get FASTA)   NCBI Sequence Viewer  
  XP_005407058 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006069
  ENSCLAP00000006069.1
RefSeq Acc Id: XP_005407057   ⟸   XM_005407000
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UVP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005407058   ⟸   XM_005407001
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UVP0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000006069   ⟸   ENSCLAT00000006172
Protein Domains
Cation/H+ exchanger


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004296 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006172 ENTREZGENE
  ENSCLAT00000006172.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1330 UniProtKB/TrEMBL
InterPro Cation/H_exchanger UniProtKB/TrEMBL
  Cation/H_exchanger_CPA1 UniProtKB/TrEMBL
  Na/H_exchanger_3/5 UniProtKB/TrEMBL
  NaH_exchanger UniProtKB/TrEMBL
NCBI Gene Slc9a3 ENTREZGENE
PANTHER PTHR10110 UniProtKB/TrEMBL
  SODIUM/HYDROGEN EXCHANGER 3 UniProtKB/TrEMBL
Pfam Na_H_Exchanger UniProtKB/TrEMBL
PRINTS NAHEXCHNGR UniProtKB/TrEMBL
  NAHEXCHNGR3 UniProtKB/TrEMBL
UniProt A0A8C2UVP0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Slc9a3  solute carrier family 9 member A3    solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3  Symbol and/or name change 5135510 APPROVED