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GENE - TERM ANNOTATION REPORT

RGD ID: 621121
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk6
Name: cyclin-dependent kinase 6
Acc ID: GO:0030332
Term: cyclin binding
Definition: Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
Definition Source(s): GOC:ai
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk6 IPICcnd3 (Rattus norvegicus)1582338RGD  
Cdk6 IPICcnd2 (Rattus norvegicus)1582338RGD  
Cdk6enablesISOCDK6 (Homo sapiens)1624291RGDUniProtKB:P24385 UniProtKB:P30279 UniProtKB:P30281 PMID:8114739

PMID:8114739
Cdk6enablesIBAFB:FBgn0016131 or MGI:104772 or MGI:88357 or PANTHER:PTN000623979 or Cdk4 (Rattus norvegicus) or Cdk6 (Rattus norvegicus) or Cdk2 (Rattus norvegicus) or TAIR:locus:2064087 or UniProtKB:P11802 or UniProtKB:P24941 or UniProtKB:Q005341600115GO_CentralGO_REF:0000033

GO_REF:0000033
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