Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor (CHEBI:77119)
Annotations: Rat: (2491) Mouse: (2486) Human: (2635) Chinchilla: (0) Bonobo: (0) Dog: (1) Squirrel: (0) Pig: (1) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor +   
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor +   
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor +   
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor +   
EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor +  
EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitor +  
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor +   
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor +   
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor +   
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189).
EC 1.1.1.205 (IMP dehydrogenase) inhibitor +   
EC 1.1.1.21 (aldehyde reductase) inhibitor +   
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor +   
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor +   
EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor +  
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor +   
EC 1.1.1.37 (malate dehydrogenase) inhibitor +  
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor +   
EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor +   

Synonyms
Related Synonyms: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitor ;   (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitors ;   9-keto-prostaglandin E2 reductase inhibitor ;   9-keto-prostaglandin E2 reductase inhibitors ;   9-ketoprostaglandin reductase inhibitor ;   9-ketoprostaglandin reductase inhibitors ;   EC 1.1.1.189 inhibitor ;   EC 1.1.1.189 inhibitors ;   PGE-9-ketoreductase inhibitor ;   PGE-9-ketoreductase inhibitors ;   PGE2 9-oxoreductase inhibitor ;   PGE2 9-oxoreductase inhibitors ;   PGE2-9-OR inhibitor ;   PGE2-9-OR inhibitors ;   PGE2-9-ketoreductase inhibitor ;   PGE2-9-ketoreductase inhibitors ;   prostaglandin 9-ketoreductase inhibitor ;   prostaglandin 9-ketoreductase inhibitors ;   prostaglandin E 9-ketoreductase inhibitor ;   prostaglandin E 9-ketoreductase inhibitors ;   prostaglandin E2-9-oxoreductase inhibitor ;   prostaglandin E2-9-oxoreductase inhibitors ;   prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitors ;   reductase, 15-hydroxy-9-oxoprostaglandin inhibitor ;   reductase, 15-hydroxy-9-oxoprostaglandin inhibitors
Xrefs: Wikipedia:Prostaglandin-E2_9-reductase

paths to the root