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Term:
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor (CHEBI:77119)
Annotations: Rat: (517) Mouse: (522) Human: (528) Chinchilla: (0) Bonobo: (0) Dog: (1) Squirrel: (0) Pig: (1)
Parent Terms Term With Siblings Child Terms
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor +   
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor +   
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor +   
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor +   
EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor +  
EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitor +  
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor +   
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor +   
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor +   
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189).
EC 1.1.1.205 (IMP dehydrogenase) inhibitor +   
EC 1.1.1.21 (aldehyde reductase) inhibitor +   
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor +   
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor +   
EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor +  
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor +   
EC 1.1.1.37 (malate dehydrogenase) inhibitor +  
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor +  
EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor +   

Synonyms
Related Synonyms: (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitor ;   (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitors ;   9-keto-prostaglandin E2 reductase inhibitor ;   9-keto-prostaglandin E2 reductase inhibitors ;   9-ketoprostaglandin reductase inhibitor ;   9-ketoprostaglandin reductase inhibitors ;   EC 1.1.1.189 inhibitor ;   EC 1.1.1.189 inhibitors ;   PGE-9-ketoreductase inhibitor ;   PGE-9-ketoreductase inhibitors ;   PGE2 9-oxoreductase inhibitor ;   PGE2 9-oxoreductase inhibitors ;   PGE2-9-OR inhibitor ;   PGE2-9-OR inhibitors ;   PGE2-9-ketoreductase inhibitor ;   PGE2-9-ketoreductase inhibitors ;   prostaglandin 9-ketoreductase inhibitor ;   prostaglandin 9-ketoreductase inhibitors ;   prostaglandin E 9-ketoreductase inhibitor ;   prostaglandin E 9-ketoreductase inhibitors ;   prostaglandin E2-9-oxoreductase inhibitor ;   prostaglandin E2-9-oxoreductase inhibitors ;   prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitors ;   reductase, 15-hydroxy-9-oxoprostaglandin inhibitor ;   reductase, 15-hydroxy-9-oxoprostaglandin inhibitors
Xrefs: Wikipedia:Prostaglandin-E2_9-reductase

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.